By Professor Georgina Hold

Journal articles

Goddard M; Hansen R; Karcher AM; Munro MJ; Berry SH; Stevenson MH; El-Omar E; Hold GL, 2011, 'Bilirubin Has Anti-Bacterial Properties Against Gram-Positive Bacteria: A Potential Benefit of Physiological Jaundice?', Gastroenterology, 140, pp. S - 941, http://dx.doi.org/10.1016/s0016-5085(11)63902-4

Mukhopadhya I; Thomson JM; Hansen R; Berry SH; El-Omar E; Hold GL, 2011, 'Detection of Campylobacter Concisus in Colonic Biopsies From Adult Patients With Ulcerative Colitis', Gastroenterology, 140, pp. S - 268, http://dx.doi.org/10.1016/s0016-5085(11)61073-1

Hansen R; Mukhopadhya I; Russell RK; Bisset WM; Berry SH; Thomson JM; El-Omar E; Hold GL, 2011, 'The Role of the Microaerophilic Colonic Microbiota in De-Novo Paediatric Inflammatory Bowel Disease', Gastroenterology, 140, pp. S - 512, http://dx.doi.org/10.1016/s0016-5085(11)62122-7

Hansen R; Cameron FL; Hold GL; El-Omar EM; Russell RK, 2010, 'Inflammatory bowel disease', Paediatrics and Child Health, 20, pp. 473 - 478, http://dx.doi.org/10.1016/j.paed.2010.04.005

Ng MTH; Van't Hof R; Crockett JC; Hope ME; Berry S; Thomson J; McLean MH; McColl KEL; El-Omar EM; Hold GL, 2010, 'Increase in NF-κB binding affinity of the variant C allele of the toll-like receptor 9 -1237T/C polymorphism is associated with Helicobacter pylori-induced gastric disease', Infection and Immunity, 78, pp. 1345 - 1352, http://dx.doi.org/10.1128/IAI.01226-09

Hansen R; Thomson JM; El-Omar EM; Hold GL, 2010, 'The role of infection in the aetiology of inflammatory bowel disease', Journal of Gastroenterology, 45, pp. 266 - 276, http://dx.doi.org/10.1007/s00535-009-0191-y

FitzGerald MP; Wehmeier S; Gangloff M; Gay N; Berry SH; Ferguson GP; El-Omar E; Hold GL, 2010, 'S1640 Can Helicobacter pylori Lipopolysaccharide Lipid a Composition Affect Its Ability to Induce an Inflammatory Response Through Toll Like Receptor 4', Gastroenterology, 138, pp. S - 244, http://dx.doi.org/10.1016/s0016-5085(10)61110-9

Saunders KA; Crockett JC; Berry SH; El-Omar E; Hold GL, 2010, 'S1641 Impact of the TLR4 Asp299Gly Polymorphism on Induction of the Inflammatory Response Following H. pylori Infection', Gastroenterology, 138, pp. S - 244, http://dx.doi.org/10.1016/s0016-5085(10)61111-0

Ng MT; Rabkin CS; Lochhead P; Lissowska J; Vaughan TL; Gammon M; Risch H; Chow W-H; Hold GL; El-Omar E, 2010, 'T2009 Assessment of Novel Genetic Polymorphisms and Risk of Upper Gastrointestinal Carcinoma', Gastroenterology, 138, pp. S - 612, http://dx.doi.org/10.1016/s0016-5085(10)62822-3

Basavaraju U; Shebl FM; Palmer AJ; Hold GL; Rabkin CS; El-Omar E, 2010, 'T2012 Cytokine Gene Polymorphisms, Cytokine Levels and Risk of Colorectal Neoplasia in the Screened Population of Northeast Scotland', Gastroenterology, 138, pp. S - 613, http://dx.doi.org/10.1016/s0016-5085(10)62825-9

El-Sakka NE; Hold GL; El-Omar E, 2010, 'W1738 Role of TLR4 in Carcinogenesis and Tumor Progression of Colorectal Cancer', Gastroenterology, 138, pp. S - 730, http://dx.doi.org/10.1016/s0016-5085(10)63358-6

Hold GL; Untiveros P; Saunders KA; El-Omar EM, 2009, 'Role of host genetics in fibrosis', Fibrogenesis and Tissue Repair, 2, pp. 6, http://dx.doi.org/10.1186/1755-1536-2-6

Hansen R; Hold GL; Berry SH; El Sakka NE; Thomson J; Bisset WM; Mahdi G; Murray GI; Helms PJ; El-Omar E, 2009, 'Are non-Pylori Helicobacter Organisms Associated with Paediatric Ulcerative Colitis? A Retrospective Observational Study', SCOTTISH MEDICAL JOURNAL, 54, pp. 54 - 55, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000272538800039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hold GL; Rabkin CS; Gammon MD; Berry SH; Smith MG; Lissowska J; Risch HA; Chow WH; Ashley G Mowat N; Vaughan TL; El-Omar EM, 2009, 'CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations', European Journal of Cancer Prevention, 18, pp. 117 - 119, http://dx.doi.org/10.1097/CEJ.0b013e3283101292

Hansen R; El-Sakka NE; Berry SH; Thomson JM; Bisset WM; Mahdi G; Murray GI; Helms PJ; Hold G; El-Omar EM, 2009, 'W1180 Are Non-Pylori Helicobacter Organisms Associated with Paediatric Ulcerative Colitis? Retrospective Observational Study', Gastroenterology, 136, pp. A - 671, http://dx.doi.org/10.1016/s0016-5085(09)63093-6

McLean MH; Murray GI; Fyfe N; Hold GL; Mowat NAG; El-Omar EM, 2008, 'COX-2 expression in sporadic colorectal adenomatous polyps is linked to adenoma characteristics', Histopathology, 52, pp. 806 - 815, http://dx.doi.org/10.1111/j.1365-2559.2008.03038.x

Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'A single nucleotide polymorphism in the TLR9 promoter (TLR9-1237T/C) increases the affinity of NF-kappa B protein binding and enhances transcriptional activity upon H-pylori infection', GASTROENTEROLOGY, 134, pp. A567 - A567, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101504189&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'Role of chronic inflammation in sporadic colorectal neoplasia', GASTROENTEROLOGY, 134, pp. A293 - A294, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101502155&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'Variable detection of entero-hepatic Helicobacter species in colonic mucosal pinch biopsies by different molecular techniques', GASTROENTEROLOGY, 134, pp. A655 - A655, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101504599&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hold GL; El-Omar EM, 2008, 'Genetic aspects of inflammation and cancer', Biochemical Journal, 410, pp. 225 - 235, http://dx.doi.org/10.1042/BJ20071341

El-Omar EM; Ng MT; Hold GL, 2008, 'Polymorphisms in Toll-like receptor genes and risk of cancer', Oncogene, 27, pp. 244 - 252, http://dx.doi.org/10.1038/sj.onc.1210912

McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'S1996 Role of Chronic Inflammation in Sporadic Colorectal Neoplasia', Gastroenterology, 134, http://dx.doi.org/10.1016/s0016-5085(08)61366-9

Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'T1807 A Single Nucleotide Polymorphism in the TLR9 Promoter (TLR9 −1237T/C) Increases the Affinity of NF-κB Protein Binding and Enhances Transcriptional Activity Upon H. pylori Infection', Gastroenterology, 134, pp. A - 567, http://dx.doi.org/10.1016/s0016-5085(08)62648-7

Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'W1208 Variable Detection of Entero-Hepatic Helicobacter Species in Colonic Mucosal Pinch Biopsies By Different Molecular Techniques', Gastroenterology, 134, pp. A - 655, http://dx.doi.org/10.1016/s0016-5085(08)63058-9

Hold GL; Rabkin CS; Chow WH; Smith MG; Gammon MD; Risch HA; Vaughan TL; McColl KEL; Lissowska J; Zatonski W; Schoenberg JB; Blot WJ; Mowat NAG; Fraumeni JF; El-Omar EM, 2007, 'A Functional Polymorphism of Toll-Like Receptor 4 Gene Increases Risk of Gastric Carcinoma and Its Precursors', Gastroenterology, 132, pp. 905 - 912, http://dx.doi.org/10.1053/j.gastro.2006.12.026

Smith MG; Hold GL; Tahara E; El-Omar EM, 2006, 'Cellular and molecular aspects of gastric cancer', World Journal of Gastroenterology, 12, pp. 2979 - 2990, http://dx.doi.org/10.3748/wjg.v12.i19.2979

Macarthur M; Sharp L; Hold GL; Little J; El-Omar EM, 2005, 'The role of cytokine gene polymorphisms in colorectal cancer and their interaction with aspirin use in the Northeast of Scotland', Cancer Epidemiology Biomarkers and Prevention, 14, pp. 1613 - 1618, http://dx.doi.org/10.1158/1055-9965.EPI-04-0878

Garza-González E; Bosques-Padilla FJ; El-Omar E; Hold G; Tijerina-Menchaca R; Maldonado-Garza HJ; Pérez-Pérez GI, 2005, 'Role of the polymorphic IL-1B, IL-1RN and TNF-A genes in distal gastric cancer in Mexico', International Journal of Cancer, 114, pp. 237 - 241, http://dx.doi.org/10.1002/ijc.20718

Hope ME; Hold GL; Kain R; El-Omar EM, 2005, 'Sporadic colorectal cancer - Role of the commensal microbiota', FEMS Microbiology Letters, 244, pp. 1 - 7, http://dx.doi.org/10.1016/j.femsle.2005.01.029

Hird HJ; Hold GL; Chisholm J; Reece P; Russell VJ; Brown J; Goodier R; MacArthur R, 2005, 'Development of a method for the quantification of haddock (Melanogrammus aeglefinus) in commercial products using real-time PCR', European Food Research and Technology, 220, pp. 633 - 637, http://dx.doi.org/10.1007/s00217-004-1050-y

Maxwell FJ; Duncan SH; Hold G; Stewart CS, 2004, 'Isolation, growth on prebiotics and probiotic potential of novel bifidobacteria from pigs', Anaerobe, 10, pp. 33 - 39, http://dx.doi.org/10.1016/j.anaerobe.2003.11.005

Macarthur M; Hold GL; El-Omar EM, 2004, 'Inflammation and Cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy', American Journal of Physiology Gastrointestinal and Liver Physiology, 286, pp. G515 - G520, http://dx.doi.org/10.1152/ajpgi.00475.2003

Strömpl C; Hold GL; Lünsdorf H; Graham J; Gallacher S; Abraham WR; Moore ERB; Timmis KN, 2003, 'Oceanicaulis alexandrii gen. nov., sp. nov., a novel stalked bacterium isolated from a culture of the dinoflagellate Alexandrium tamarense (Lebour) Balech', International Journal of Systematic and Evolutionary Microbiology, 53, pp. 1901 - 1906, http://dx.doi.org/10.1099/ijs.0.02635-0

Calo-Mata P; Sotelo CG; Pérez-Martín RI; Rehbein H; Hold GL; Russell VJ; Pryde S; Quinteiro J; Rey-Méndez M; Rosa C; Santos AT, 2003, 'Identification of gadoid fish species using DNA-based techniques', European Food Research and Technology, 217, pp. 259 - 264, http://dx.doi.org/10.1007/s00217-003-0735-y

Hold GL; Schwiertz A; Aminov RI; Blaut M; Flint HJ, 2003, 'Oligonucleotide probes that detect quantitatively significant groups of butyrate-producing bacteria in human feces', Applied and Environmental Microbiology, 69, pp. 4320 - 4324, http://dx.doi.org/10.1128/AEM.69.7.4320-4324.2003

Garza-González E; Hold G; Pérez-Pérez GI; Bosques-Padilla FJ; Tijerina-Menchaca R; Maldonado-Garza HJ; el-Omar E, 2003, 'Role of polymorphism of certain cytokines in gastric cancer in Mexico. Preliminary results', Revista De Gastroenterologia De Mexico, 68, pp. 107 - 112

Troost E; Hold GL; Smith MG; Chow WH; Rabkin CS; McColl KEL; El-Omar EM, 2003, 'The role of interleukin-1beta and other potential genetic markers as indicators of gastric cancer risk.', Canadian Journal of Gastroenterology Journal Canadien De Gastroenterologie, 17 Suppl B, http://dx.doi.org/10.1155/2003/397060

Pryde SE; Duncan SH; Hold GL; Stewart CS; Flint HJ, 2002, 'The microbiology of butyrate formation in the human colon', FEMS Microbiology Letters, 217, pp. 133 - 139, http://dx.doi.org/10.1016/S0378-1097(02)01106-0

Pryde S, 2002, 'The microbiology of butyrate formation in the human colon', FEMS Microbiology Letters, 217, pp. 133 - 139, http://dx.doi.org/10.1016/s0378-1097(02)01106-0

Rehbein H; Sotelo CG; Perez-Martin RI; Chapela-Garrido MJ; Hold GL; Russell VJ; Pryde SE; Santos AT; Rosa C; Quinteiro J; Rey-Mendez M, 2002, 'Differentiation of raw or processed eel by PCR-based techniques: Restriction fragment length polymorphism analysis (RFLP) and single strand conformation polymorphism analysis (SSCP)', European Food Research and Technology, 214, pp. 171 - 177, http://dx.doi.org/10.1007/s00217-001-0457-y

Duncan SH; Hold GL; Harmsen HJM; Stewart CS; Flint HJ, 2002, 'Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov', International Journal of Systematic and Evolutionary Microbiology, 52, pp. 2141 - 2146, http://dx.doi.org/10.1099/ijs.0.02241-0

Duncan SH, 2002, 'Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov', INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 52, pp. 2141 - 2146, http://dx.doi.org/10.1099/ijs.0.02241-0

Duncan SH; Hold GL; Barcenilla A; Stewart CS; Flint HJ, 2002, 'Roseburia intestinalis sp. nov., a novel saccharolytic, butyrate-producing bacterium from human faeces', International Journal of Systematic and Evolutionary Microbiology, 52, pp. 1615 - 1620, http://dx.doi.org/10.1099/ijs.0.02143-0

Duncan SH; Hold GL; Barcenilla A; Stewart CS; Flint HJ, 2002, 'Roseburia intestinalis sp. nov., a novel saccharolytic, butyrate-producing bacterium from human faeces.', International Journal of Systematic and Evolutionary Microbiology, 52, pp. 1615 - 1620, http://dx.doi.org/10.1099/00207713-52-5-1615

Hold GL; Pryde SE; Russell VJ; Furrie E; Flint HJ, 2002, 'Assessment of microbial diversity in human colonic samples by 16S rDNA sequence analysis', FEMS Microbiology Ecology, 39, pp. 33 - 39, http://dx.doi.org/10.1016/S0168-6496(01)00190-8

Schwiertz A; Hold GL; Duncan SH; Gruhl B; Collins MD; Lawson PA; Flint HJ; Blaut M, 2002, 'Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces', Systematic and Applied Microbiology, 25, pp. 46 - 51, http://dx.doi.org/10.1078/0723-2020-00096

Chapela MJ; Sotelo CG; Calo-Mata P; Pérez-Martín RI; Rehbein H; Hold GL; Quinteiro J; Rey-Méndez M; Rosa C; Santos AT, 2002, 'Identification of Cephalopod Species (Ommastrephidae and Loliginidae) in Seafood Products by Forensically Informative Nucleotide Sequencing (FINS)', Journal of Food Science, 67, pp. 1672 - 1676, http://dx.doi.org/10.1111/j.1365-2621.2002.tb08703.x

Hold G, 2002, 'Assessment of microbial diversity in human colonic samples by 16S rDNA sequence analysis', FEMS Microbiology Ecology, 39, pp. 33 - 39, http://dx.doi.org/10.1016/s0168-6496(01)00190-8

Rehbein H; Sotelo CG; Perez-Martin RI; Chapela-Garrido MJ; Hold GL; Russell VJ; Pryde SE; Santos AT; Rosa C; Quinteiro J; Rey-Mendez M, 2002, 'Differentiation of raw or processed eel by PCR-based techniques: restriction fragment length polymorphism analysis (RFLP) and single strand conformation polymorphism analysis (SSCP)', EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 214, pp. 171 - 177, http://dx.doi.org/10.1007/s00217-001-0457-y

Quinteiro J; Vidal R; Izquierdo M; Sotelo CG; Chapela MJ; Pérez-Martín RI; Rehbein H; Hold GL; Russell VJ; Pryde SE; Rosa C; Santos AT; Rey-Méndez M, 2001, 'Identification of hake species (Merluccius genus) using sequencing and PCR-RFLP analysis of mitochondrial DNA control region sequences', Journal of Agricultural and Food Chemistry, 49, pp. 5108 - 5114, http://dx.doi.org/10.1021/jf010421f

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