By Professor Georgina Hold

Journal articles

Williams AJ; Paramsothy R; Wu N; Ghaly S; Leach S; Paramsothy S; Corte C; O'Brien C; Burke C; Wark G; Samocha-Bonet D; Lambert K; Ahlenstiel G; Wasinger V; Dutt S; Pavli P; Grimm M; Lemberg D; Connor S; Leong R; Hold G, 2021, 'Australia IBD Microbiome (AIM) Study: Protocol for a multicentre longitudinal prospective cohort study', BMJ Open, 11, http://dx.doi.org/10.1136/bmjopen-2020-042493

Susic D; Davis G; O'Sullivan AJ; McGovern E; Harris K; Roberts LM; Craig ME; Mangos G; Hold GL; El-Omar EM; Henry A, 2020, 'Microbiome Understanding in Maternity Study (MUMS), an Australian prospective longitudinal cohort study of maternal and infant microbiota: study protocol', BMJ Open, 10, pp. e040189, http://dx.doi.org/10.1136/bmjopen-2020-040189

Link A; Hold G, 2020, 'First Case of Covid-19 in the United States', The New England journal of medicine, 382, pp. e53, http://dx.doi.org/10.1056/NEJMc2004794

Bezawada N; Phang TH; Hold GL; Hansen R, 2020, 'Autism Spectrum Disorder and the Gut Microbiota in Children: A Systematic Review', Annals of Nutrition and Metabolism, 76, pp. 16 - 29, http://dx.doi.org/10.1159/000505363

Rajilic-Stojanovic M; Figueiredo C; Smet A; Hansen R; Kupcinskas J; Rokkas T; Andersen L; Machado JC; Ianiro G; Gasbarrini A; Leja M; Gisbert JP; Hold GL, 2020, 'Systematic review: gastric microbiota in health and disease', Alimentary Pharmacology and Therapeutics, 51, pp. 582 - 602, http://dx.doi.org/10.1111/apt.15650

Ormsby MJ; Johnson SA; Carpena N; Meikle LM; Goldstone RJ; McIntosh A; Wessel HM; Hulme HE; McConnachie CC; Connolly JPR; Roe AJ; Hasson C; Boyd J; Fitzgerald E; Gerasimidis K; Morrison D; Hold GL; Hansen R; Walker D; Smith DGE; Wall DM, 2020, 'Propionic Acid Promotes the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli', Cell Reports, 30, pp. 2297 - 2305.e5, http://dx.doi.org/10.1016/j.celrep.2020.01.078

Keller JJ; Vehreschild MJGT; Hvas CL; Jorgensen SMD; Kupciskas J; Link A; Mulder CJJ; Goldenberg SD; Arasaradnam R; Sokol H; Gasbarrini A; Hoegenauer C; Terveer EM; Kuijper EJ; Arkkila P; Gasbarrini A; Gridnyev O; Megraud F; Kump PK; Nakov R; Goldenberg SD; Satokari R; Tkatch S; Sanguinetti M; Sokol H; Cammarota G; Dorofeev A; Keller JJ; Hoegenauer C; Gubska O; Ianiro G; Mattila E; Ooijevaar RE; Arasaradnam R; Sarin SK; Sood A; Putignani L; Alric L; Arkkila P; Hvas CL; Jorgensen SMD; Kuijper EJ; Kupciskas J; Link A; Mulder CJJ; Williams HRT; Goorhuis A; Verspaget HW; Terveer EM; Hold GL; Tilg H; Ponsioen CY, 2019, 'Stool for fecal microbiota transplantation should be classified as a transplant product and not as a drug', UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, 7, pp. 1408 - 1410, http://dx.doi.org/10.1177/2050640619887579

Gemmell M; Berry S; Mukhopadhya I; Gong L; Hansen R; Hold G, 2019, 'Draft genome sequences of a Campylobacter curvus and three Campylobacter ureolyticus strains isolated from human colonic mucosal tissue', Microbiota in Health and Disease, 1, pp. e148 - e148, http://dx.doi.org/10.26355/mhd_201911_148

Rokkas T; Gisbert JP; Gasbarrini A; Hold GL; Tilg H; Malfertheiner P; Megraud F; O'Morain C, 2019, 'A network meta-analysis of randomized controlled trials exploring the role of fecal microbiota transplantation in recurrent Clostridium difficile infection', United European Gastroenterology Journal, 7, pp. 1051 - 1063, http://dx.doi.org/10.1177/2050640619854587

Hold GL; Allen-Vercoe E, 2019, 'Gut microbial biofilm composition and organisation holds the key to CRC', Nature Reviews Gastroenterology and Hepatology, 16, pp. 329 - 330, http://dx.doi.org/10.1038/s41575-019-0148-4

Ormsby MJ; Logan M; Johnson SA; McIntosh A; Fallata G; Papadopoulou R; Papachristou E; Hold GL; Hansen R; Ijaz UZ; Russell RK; Gerasimidis K; Wall DM, 2019, 'Inflammation associated ethanolamine facilitates infection by Crohn's disease-linked adherent-invasive Escherichia coli', Ebiomedicine, 43, pp. 325 - 332, http://dx.doi.org/10.1016/j.ebiom.2019.03.071

Mukhopadhya I; Segal JP; Carding SR; Hart AL; Hold GL, 2019, 'The gut virome: the ‘missing link’ between gut bacteria and host immunity?', Therapeutic Advances in Gastroenterology, 12, http://dx.doi.org/10.1177/1756284819836620

Hsu T; Gemmell MR; Franzosa EA; Berry S; Mukhopadhya I; Hansen R; Michaud M; Nielsen H; Miller WG; Nielsen H; Bajaj-Elliott M; Huttenhower C; Garrett WS; Hold GL, 2019, 'Comparative genomics and genome biology of Campylobacter showae', Emerging Microbes and Infections, 8, pp. 827 - 840, http://dx.doi.org/10.1080/22221751.2019.1622455

Hold GL; Hansen R, 2019, 'Impact of the gastrointestinal microbiome in health and disease: Co-evolution with the host immune system', , 421, pp. 303 - 318, http://dx.doi.org/10.1007/978-3-030-15138-6_12

Bond A; Greenwood R; Lewis S; Corfe B; Sarkar S; O’Toole P; Rooney P; Burkitt M; Hold G; Probert C, 2019, 'Volatile organic compounds emitted from faeces as a biomarker for colorectal cancer', Alimentary Pharmacology and Therapeutics, 49, pp. 1005 - 1012, http://dx.doi.org/10.1111/apt.15140

Mahalhal A; Burkitt M; Duckworth C; Hold G; Campbell B; Pritchard M; Probert C, 2019, 'Long-term iron deficiency and iron supplementation exacerbate acute DSS-induced colitis and are associated with significant dysbiosis', , http://dx.doi.org/10.1101/585174

Hansen R; Gibson S; De Paiva Alves E; Goddard M; MacLaren A; Karcher AM; Berry S; Collie-Duguid ESR; El-Omar E; Munro M; Hold GL, 2018, 'Adaptive response of neonatal sepsis-derived Group B Streptococcus to bilirubin', Scientific Reports, 8, pp. 6470, http://dx.doi.org/10.1038/s41598-018-24811-3

Gemmell MR; Berry S; Mukhopadhya I; Hansen R; Nielsen HL; Bajaj-Elliott M; Nielsen H; Hold GL, 2018, 'Comparative genomics of Campylobacter concisus: Analysis of clinical strains reveals genome diversity and pathogenic potential', Emerging Microbes and Infections, 7, http://dx.doi.org/10.1038/s41426-018-0118-x

Ianiro G; Maida M; Burisch J; Simonelli C; Hold G; Ventimiglia M; Gasbarrini A; Cammarota G, 2018, 'Efficacy of different faecal microbiota transplantation protocols for Clostridium difficile infection: A systematic review and meta-analysis', United European Gastroenterology Journal, 6, pp. 1232 - 1244, http://dx.doi.org/10.1177/2050640618780762

McIlroy JR; Nalagatla N; Hansen R; Hart A; Hold GL, 2018, 'Faecal microbiota transplantation as a treatment for inflammatory bowel disease: A national survey of adult and paediatric gastroenterologists in the UK', Frontline Gastroenterology, 9, pp. 250 - 255, http://dx.doi.org/10.1136/flgastro-2017-100936

Mahalhal A; Williams JM; Johnson S; Ellaby N; Duckworth CA; Burkitt MD; Liu X; Hold GL; Campbell BJ; Mark Pritchard D; Probert CS, 2018, 'Oral iron exacerbates colitis and influences the intestinal microbiome', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0202460

Kupcinskas J; Hold GL, 2018, 'Other Helicobacters and the gastric microbiome', Helicobacter, 23, http://dx.doi.org/10.1111/hel.12521

Garg M; Hendy P; Ding JN; Shaw S; Hold G; Hart A, 2018, 'The effect of Vitamin D on intestinal inflammation and faecal microbiota in patients with ulcerative colitis', Journal of Crohn S and Colitis, 12, pp. 963 - 972, http://dx.doi.org/10.1093/ecco-jcc/jjy052

Kennedy NA; Lamb CA; Berry SH; Walker AW; Mansfield J; Parkes M; Simpkins R; Tremelling M; Nutland S; Parkhill J; Probert C; Hold GL; Lees CW, 2018, 'The impact of NOD2 variants on fecal microbiota in Crohn's disease and controls without gastrointestinal disease', Inflammatory Bowel Diseases, 24, pp. 583 - 592, http://dx.doi.org/10.1093/ibd/izx061

Segal JP; Oke S; Hold GL; Clark SK; Faiz OD; Hart AL, 2018, 'Systematic review: ileoanal pouch microbiota in health and disease', Alimentary Pharmacology and Therapeutics, 47, pp. 466 - 477, http://dx.doi.org/10.1111/apt.14454

McIlroy J; Nalagatla N; Hansen R; Hart A; Hold G, 2018, 'P659 FMT as a treatment for IBD: A national survey of gastroenterologists in the UK', Journal of Crohn's and Colitis, 12, pp. S443 - S444, http://dx.doi.org/10.1093/ecco-jcc/jjx180.786

Douglas GM; Hansen R; Jones CMA; Dunn KA; Comeau AM; Bielawski JP; Tayler R; El-Omar EM; Russell RK; Hold GL; Langille MGI; Limbergen JV, 2018, 'Multi-omics differentially classify disease state and treatment outcome in pediatric Crohn's disease', Microbiome, 6, pp. 13, http://dx.doi.org/10.1186/s40168-018-0398-3

Brunner K; John CM; Phillips NJ; Alber DG; Gemmell MR; Hansen R; Nielsen HL; Hold GL; Bajaj-Elliott M; Jarvis GA, 2018, 'Novel Campylobacter concisus lipooligosaccharide is a determinant of inflammatory potential and virulence', Journal of Lipid Research, 59, pp. 1893 - 1905, http://dx.doi.org/10.1194/jlr.M085860

McIlroy J; Ianiro G; Mukhopadhya I; Hansen R; Hold GL, 2018, 'Review article: the gut microbiome in inflammatory bowel disease—avenues for microbial management', Alimentary Pharmacology and Therapeutics, 47, pp. 26 - 42, http://dx.doi.org/10.1111/apt.14384

Lawler M; Alsina D; Adams RA; Anderson AS; Brown G; Fearnhead NS; Fenwick SW; Halloran SP; Hochhauser D; Hull MA; Koelzer VH; McNair AGK; Monahan KJ; Näthke I; Norton C; Novelli MR; Steele RJC; Thomas AL; Wilde LM; Wilson RH; Tomlinson I; Bowel Cancer UK Critical Research Gaps in Colorectal Cancer Initiative , 2018, 'Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer.', Gut, 67, pp. 179 - 193, http://dx.doi.org/10.1136/gutjnl-2017-315333

Mahalhal A; Williams J; Johnson S; Ellaby N; Duckworth C; Burkitt M; Liu X; Hold G; Campbell B; Pritchard M; Probert C, 2018, 'Oral iron exacerbates colitis and influences the intestinal microbiome', , http://dx.doi.org/10.1101/385997

Boyle SE; Cotton SC; Myint PK; Hold GL, 2017, 'The influence of early research experience in medical school on the decision to intercalate and future career in clinical academia: A questionnaire study', BMC Medical Education, 17, pp. 245, http://dx.doi.org/10.1186/s12909-017-1066-1

Maida M; Macaluso FS; Ianiro G; Mangiola F; Sinagra E; Hold G; Maida C; Cammarota G; Gasbarrini A; Scarpulla G, 2017, 'Screening of colorectal cancer: present and future', Expert Review of Anticancer Therapy, 17, pp. 1131 - 1146, http://dx.doi.org/10.1080/14737140.2017.1392243

Berry SH; El-Omar EM; Hold GL; Mukhopadhya A, 2017, 'THE EFFECT OF LACTULOSE ON THE FAECAL MICROBIOTA OF PATIENTS WITH MINIMAL HEPATIC ENCEPHALOPATHY', GASTROENTEROLOGY, 152, pp. S1049 - S1049, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000403140304299&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Mukhopadhya I; Murdoch H; Berry S; Hunt A; Iturriza-Gomara M; Smith-Palmer A; Cameron JC; Hold GL, 2017, 'Changing molecular epidemiology of rotavirus infection after introduction of monovalent rotavirus vaccination in Scotland', Vaccine, 35, pp. 156 - 163, http://dx.doi.org/10.1016/j.vaccine.2016.11.028

Watt E; Gemmell MR; Berry S; Glaire M; Farquharson F; Louis P; Murray GI; El-Omar E; Hold GL, 2016, 'Extending colonic mucosal microbiome analysis-assessment of colonic lavage as a proxy for endoscopic colonic biopsies', Microbiome, 4, pp. 61, http://dx.doi.org/10.1186/s40168-016-0207-9

Mukhopadhya I; Murray GI; Duncan L; Yuecel R; Shattock R; Kelly C; Iannelli F; Pozzi G; El-Omar EM; Hold GL; Hijazi K, 2016, 'Transporters for antiretroviral drugs in colorectal CD4+ T cells and circulating α4β7 integrin CD4+ T cells: Implications for HIV microbicides', Molecular Pharmaceutics, 13, pp. 3334 - 3340, http://dx.doi.org/10.1021/acs.molpharmaceut.6b00351

Hold GL, 2016, 'Gastrointestinal Microbiota and Colon Cancer', Digestive Diseases, 34, pp. 244 - 250, http://dx.doi.org/10.1159/000443358

Mukhopadhya I; Murray GI; Berry S; Thomson J; Frank B; Gwozdz G; Ekeruche-Makinde J; Shattock R; Kelly C; Iannelli F; Pozzi G; El-Omar EM; Hold GL; Hijazi K, 2016, 'Drug transporter gene expression in human colorectal tissue and cell lines: Modulation with antiretrovirals for microbicide optimization', Journal of Antimicrobial Chemotherapy, 71, pp. 372 - 386, http://dx.doi.org/10.1093/jac/dkv335

Marchesi JR; Adams DH; Fava F; Hermes GDA; Hirschfield GM; Hold G; Quraishi MN; Kinross J; Smidt H; Tuohy KM; Thomas LV; Zoetendal EG; Hart A, 2016, 'The gut microbiota and host health: A new clinical frontier', Gut, 65, pp. 330 - 339, http://dx.doi.org/10.1136/gutjnl-2015-309990

Porter R; Murray GI; Petty R; El-Omar EM; Hold G; McLean MH, 2016, 'HMGB1 AS A PROGNOSTIC BIOMARKER IN THE PROGRESSION OF BARRETT'S OESOPHAGUS', GUT, 65, pp. A133 - A133, http://dx.doi.org/10.1136/gutjnl-2016-312388.239

Hansen R; Scott KP; Khan S; Martin JC; Berry SH; Stevenson M; Okpapi A; Munro MJ; Hold GL, 2015, 'First-Pass Meconium Samples from Healthy Term Vaginally-Delivered Neonates: An Analysis of the Microbiota', Plos One, 10, http://dx.doi.org/10.1371/journal.pone.0133320

Hijazi K; Cuppone AM; Smith K; Stincarelli MA; Ekeruche-Makinde J; De Falco G; Hold GL; Shattock R; Kelly CG; Pozzi G; Iannelli F, 2015, 'Expression of genes for drug transporters in the human female genital tract and modulatory effect of antiretroviral drugs', Plos One, 10, http://dx.doi.org/10.1371/journal.pone.0131405

Basavaraju U; Shebl FM; Palmer AJ; Berry S; Hold GL; El-Omar EM; Rabkin CS, 2015, 'Cytokine gene polymorphisms, cytokine levels and the risk of colorectal neoplasia in a screened population of Northeast Scotland', European Journal of Cancer Prevention, 24, pp. 296 - 304, http://dx.doi.org/10.1097/CEJ.0000000000000087

Mukhopadhya I; Hansen R; Meharg C; Thomson JM; Russell RK; Berry SH; El-Omar EM; Hold GL, 2015, 'The fungal microbiota of de-novo paediatric inflammatory bowel disease', Microbes and Infection, 17, pp. 304 - 310, http://dx.doi.org/10.1016/j.micinf.2014.12.001

Hijazi K; Lowe T; Meharg C; Berry SH; Foley J; Hold GL, 2015, 'Mucosal microbiome in patients with recurrent aphthous stomatitis', Journal of Dental Research, 94, pp. 87 - 94, http://dx.doi.org/10.1177/0022034514565458

Hold GL; Garrett WS, 2015, 'Gut microbiota: Microbiota organization-a key to understanding CRC development', Nature Reviews Gastroenterology and Hepatology, 12, pp. 128 - 129, http://dx.doi.org/10.1038/nrgastro.2015.25

Connors J; Hansen R; Dunn KA; Langille MG; Russell RK; Otley AR; MacIntyre B; El-Omar E; Bielawski JP; Hold GL; Van Limbergen J, 2015, '169 Assessment of Community Structure and Predictive Functional Profiling of the Mucosa-Associated Microbiome Implicates Alterations in Benzoate Metabolism in ‘de novo’ IBD After Pouch-Surgery and in Treatment-Naïve Pediatric IBD', Gastroenterology, 148, pp. S - 45, http://dx.doi.org/10.1016/s0016-5085(15)30158-x

Liu JZ; van Sommeren S; Huang H; Ng SC; Alberts R; Takahashi A; Ripke S; Lee JC; Jostins L; Shah T; Abedian S; Cheon JH; Cho J; Dayani NE; Franke L; Fuyuno Y; Hart A; Juyal RC; Juyal G; Kim WH; Morris AP; Poustchi H; Newman WG; Midha V; Orchard TR; Vahedi H; Sood A; Sung JY; Malekzadeh R; Westra H-J; Yamazaki K; Yang S-K; International Multiple Sclerosis Genetics Consortium ; International IBD Genetics Consortium ; Barrett JC; Alizadeh BZ; Parkes M; Bk T; Daly MJ; Kubo M; Anderson CA; Weersma RK, 2015, 'Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.', Nat Genet, 47, pp. 979 - 986, http://dx.doi.org/10.1038/ng.3359

Khan S; Hansen R; Scott KP; Martin JC; Berry SH; Stevenson M; Okapapi A; Hold GL; Munro M, 2015, 'G116(P) The human gut is probably sterile at birth', Archives of Disease in Childhood, 100, pp. A50.3 - A51, http://dx.doi.org/10.1136/archdischild-2015-308599.115

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