By Professor Sally Dunwoodie

Journal articles

Kusumi K; Dunwoodie SL; Krumlauf R, 2001, 'Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system', Mechanisms of Development, 100, pp. 141 - 144, http://dx.doi.org/10.1016/S0925-4773(00)00514-1

Harrison SM; Houzelstein D; Dunwoodie SL; Beddington RSP, 2000, 'Sp5, a new member of the Sp1 family, is dynamically expressed during development and genetically interacts with Brachyury', Developmental Biology, 227, pp. 358 - 372, http://dx.doi.org/10.1006/dbio.2000.9878

Shioda T; Lechleider RJ; Dunwoodie SL; Li H; Yahata T; De Caestecker MP; Fenner MH; Roberts AB; Isselbacher KJ, 1998, 'Transcriptional activating activity of Smad4: Roles of SMAD hetero-oligomerization and enhancement by an associating transactivator', Proceedings of the National Academy of Sciences of the United States of America, 95, pp. 9785 - 9790, http://dx.doi.org/10.1073/pnas.95.17.9785

Dunwoodie SL; Rodriguez TA; Beddington RSP, 1998, 'Msg1 and mrg1, founding members of a gene family, show distinct patterns of gene expression during mouse embryogenesis', Mechanisms of Development, 72, pp. 27 - 40, http://dx.doi.org/10.1016/S0925-4773(98)00011-2

Dunwoodie SL; Henrique D; Harrison SM; Beddington RSP, 1997, 'Mouse Dll3: A novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo', Development, 124, pp. 3065 - 3076

Sturm KS; Berger CN; Zhou SX; Dunwoodie SL; Tan SS; Tam PPL, 1997, 'Unrestricted lineage differentiation of parthenogenetic ES cells', Development Genes and Evolution, 206, pp. 377 - 388, http://dx.doi.org/10.1007/s004270050067

Harrison SM; Dunwoodie SL; Arkell RM; Lehrach H; Beddington RSP, 1995, 'Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo', Development, 121, pp. 2479 - 2489

Dunwoodie SL; Joya JE; Arkell RM; Hardeman EC, 1994, 'Multiple regions of the human cardiac actin gene are necessary for maturation-based expression in striated muscle', Journal of Biological Chemistry, 269, pp. 12212 - 12219, http://dx.doi.org/10.1016/s0021-9258(17)32703-5

Sutherland CJ; Elsom VL; Gordon ML; Dunwoodie SL; Hardeman EC, 1991, 'Coordination of skeletal muscle gene expression occurs late in mammalian development', Developmental Biology, 146, pp. 167 - 178, http://dx.doi.org/10.1016/0012-1606(91)90457-E

Conference Papers

Tarr I; Hesselson S; Iismaa S; Troup M; Young P; Mishra K; Wong C; Junday K; Humphreys D; Dunwoodie S; Fatkin D; Muller D; Graham RM; Giannoulatou E, 2021, 'Disease-Specific and Comorbidity-Related Polygenic Risk in Spontaneous Coronary Artery Dissection', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000752020004372&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Blue GM; Ip E; Sholler GF; Harvey RP; Giannoulatou E; Dunwoodie SL; Winlaw DS, 2019, 'Whole Genome Sequencing Provides Insight Into the Genetic Composition Underlying CHD Severity', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, PA, Philadelphia, presented at Scientific Sessions of the American-Heart-Association, PA, Philadelphia, 16 November 2019 - 18 November 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000529998004425&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Page DJ; Miossec MJ; Williams SG; Monaghan RM; Fotiou E; Cordell HJ; Sutcliffe L; Topf A; Bourgey M; Bourque G; Eveleigh R; Dunwoodie SL; Winlaw DS; Bhattacharya S; Breckpot J; Devriendt K; Gewillig M; Brook D; Setchfield K; Bu'Lock FA; O'Sullivan J; Stuart G; Bezzina C; Mulder BJM; Postma AV; Bentham JR; Baron M; Bhaskar SS; Black GC; Newman WG; Hentges KE; Lathrop M; Santibanez-Koref M; Keavney BD, 2019, 'IDENTIFICATION OF THE MAJOR GENETIC CONTRIBUTORS TO TETRALOGY OF FALLOT', in HEART, BMJ PUBLISHING GROUP, ENGLAND, Manchester, pp. A182 - A183, presented at Annual Conference of the British-Cardiovascular-Society (BCS) - Digital Health Revolution, ENGLAND, Manchester, 03 June 2019 - 05 June 2019, http://dx.doi.org/10.1136/heartjnl-2019-BCS.226

Blue GM; Ip E; Walker K; Kirk EP; Loughran-Fowlds A; Sholler GF; Dunwoodie SL; Harvey RP; Giannoulatou E; Badawi N; Winlaw DS, 2017, 'Genetic Variants Explaining Neurodevelopmental Disorders in Patients With Congenital Heart Disease - Are We Ready for the Clinic?', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, CA, Anaheim, presented at Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, CA, Anaheim, 11 November 2017 - 15 November 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000437035905488&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Fisher RE; Chapman G; Dunwoodie SL; Kusumi K, 2016, 'The Application of Iodine-Enhanced Micro-CT Scanning Protocols to Analyze Multiple Tissue Types and Organ Systems in Mouse Embryos with Short-term Gestational Hypoxia', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, CA, San Diego, presented at Experimental Biology Meeting, CA, San Diego, 02 April 2016 - 06 April 2016

Fisher RE; Chapman G; Dunwoodie SL; Kusumi K, 2016, 'The Application of Iodine-Enhanced Micro-CT Scanning Protocols to Analyze Multiple Tissue Types and Organ Systems in Mouse Embryos with Short-term Gestational Hypoxia', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 April 2016 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444004137&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Fisher RE; Chapman G; Dunwoodie SL; Kusumi K, 2016, 'The Application of Iodine-Enhanced Micro-CT Scanning Protocols to Analyze Multiple Tissue Types and Organ Systems in Mouse Embryos with Short-term Gestational Hypoxia', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 April 2016 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444004645&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Fisher RE; Chapman G; Dunwoodie SL; Kusumi K, 2016, 'The Application of Iodine-Enhanced Micro-CT Scanning Protocols to Analyze Multiple Tissue Types and Organ Systems in Mouse Embryos with Short-term Gestational Hypoxia', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 April 2016 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444001286&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Du J; Chen Y; Li Q; Wang Z; Dunwoodie S; Bunting KD; Yang Y-C, 2011, 'Cited2 Regulates Hematopoietic Stem Cell Quiescence Through HIF-1 alpha Dependent and Independent Pathways', in BLOOD, AMER SOC HEMATOLOGY, CA, San Diego, pp. 416 - 417, presented at 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, CA, San Diego, 10 December 2011 - 13 December 2011

Cantley J; Davenport A; Dunwoodie SL; Biden TJ, 2011, 'Deletion of the Cited2 gene in beta cells causes impaired insulin secretion and glucose intolerance in mice', in DIABETOLOGIA, SPRINGER, PORTUGAL, Lisbon, pp. S21 - S21, presented at 47th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), PORTUGAL, Lisbon, 12 September 2011 - 16 September 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000307671300035&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Artap S; Lopes Floro K; Saga Y; Hamada H; Sparrow DB; Dunwoodie SL, 2009, 'Cited2 transactivates Nodal expression in the left lateral plate mesoderm through interaction with FoxH1', in Mechanisms of Development, Elsevier Science BV, Amsterdam, Netherlands, pp. S188 - S188, presented at 16th International Society of Developmental Biologists Congress, Edinburgh, http://dx.doi.org/10.1016/j.mod.2009.06.453

Stevens S; Gonzalez D; Pratt S; Dunwoodie SL; Loomes K; Kusumi K, 2008, 'Notch pathway mutants display craniofacial birth defects and disrupt expression of the pharyngeal arch gene Barx1', in Developmental Biology, Academic Press Inc Elsevier Science, San Diego, Ca, USA, pp. 585 - 586, presented at Society for Developmental Biology 67th Annual Meeting Program, http://dx.doi.org/10.1016/j.ydbio.2008.05.421

Kusumi K; Stevens SA; Mimoto MS; Dunwoodie SL; Loomes KM, 2003, 'Dll3-Notch1 double mutant mice are a model for congenital scoliosis and craniofacial disorders.', in AMERICAN JOURNAL OF HUMAN GENETICS, UNIV CHICAGO PRESS, CALIFORNIA, LOS ANGELES, pp. 172 - 172, presented at Annual Meeting of the American-Society-of-Human-Genetics, CALIFORNIA, LOS ANGELES, 04 November 2003 - 08 November 2003, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000185599700052&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sparrow DB; Withington SL; Scott AN; Preis J; Rodriguez T; Beddington RSP; Dunwoodie SL, 2003, 'Cited1 is required for normal placental development in mouse.', in DEVELOPMENTAL BIOLOGY, ACADEMIC PRESS INC ELSEVIER SCIENCE, MASSACHUSETTS, BOSTON, pp. 558 - 558, presented at 62nd Annual Meeting of the Society-for-Development-Biology, MASSACHUSETTS, BOSTON, 30 July 2003 - 02 August 2003, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000184373300465&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Capra V; De Marco P; Moroni A; Merello E; Raso A; Dunwoodie S; Carna A, 2002, 'CITED2 is not a major determinant of human NTDs.', in AMERICAN JOURNAL OF HUMAN GENETICS, UNIV CHICAGO PRESS, MARYLAND, BALTIMORE, pp. 468 - 468, presented at 52nd Annual Meeting of the American-Society-of-Human-Genetics, MARYLAND, BALTIMORE, 15 October 2002 - 19 October 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000178025801743&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts

McGrath-Cadell L; Hesselson S; Tarr I; Iismaa SE; Bax M; Junday K; Dunwoodie SE; Fatkin D; Kovacic J; Muller DWM; Giannoulatou E; Graham RM, 2021, 'Spontaneous Coronary Artery Dissection (SCAD) and a family history of aortic artery dissection, a case series', in EUROPEAN HEART JOURNAL, OXFORD UNIV PRESS, Vol. 42, pp. 2787 - 2787, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000720456903088&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McGrath-Cadell L; Hesselson S; Iismaa SE; Mishra K; Wong CMY; Fatkin D; Dunwoodie SL; Harvey R; Holloway CJ; Muller DWM; Giannoulatou E; Graham RM, 2019, 'Familial clustering of spontaneous coronary artery dissection', in EUROPEAN HEART JOURNAL, OXFORD UNIV PRESS, FRANCE, Paris, Vol. 40, pp. 3414 - 3414, presented at Congress of the European-Society-of-Cardiology (ESC) / World Congress of Cardiology, FRANCE, Paris, 31 August 2019 - 04 September 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000507313003083&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Dunwoodie SL, 2018, 'THE ROLE OF GENETIC AND ENVIRONMENTAL FACTORS IN CAUSING CONGENITAL MALFORMATION', in AMERICAN JOURNAL OF MEDICAL GENETICS PART A, WILEY, CANADA, Banff, Vol. 179, pp. 686 - 686, presented at 39th Annual David W Smith Workshop on Malformations and Morphogenesis, CANADA, Banff, 24 August 2018 - 29 August 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000462676800054&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Dunwoodie S, 2017, 'Gestational stress causes heart defects by inducing the unfolded protein response', in MECHANISMS OF DEVELOPMENT, ELSEVIER SCIENCE BV, SINGAPORE, Natil Univ Singapore, Singapore, Vol. 145, pp. S17 - S17, presented at 18th International Congress of Developmental Biology, SINGAPORE, Natil Univ Singapore, Singapore, 18 June 2017 - 22 June 2017, http://dx.doi.org/10.1016/j.mod.2017.04.572

Moreau JLM; Shi H; O'Reilly VC; Bewes TR; Yam MX; Chapman BE; Grieve SM; Stocker R; Graham RM; Chapman G; Sparrow DB; Dunwoodie SL, 2017, 'Gestational stress induces the unfolded protein response, resulting in heart defects', in MECHANISMS OF DEVELOPMENT, ELSEVIER SCIENCE BV, SINGAPORE, Natil Univ Singapore, Singapore, Vol. 145, pp. S67 - S68, presented at 18th International Congress of Developmental Biology, SINGAPORE, Natil Univ Singapore, Singapore, 18 June 2017 - 22 June 2017, http://dx.doi.org/10.1016/j.mod.2017.04.152

Preprints

Ward AO; Schonrock N; McCann AJ; Phanor SK; Kock KH; Kurland JV; Wu F; Murray NJ; Walshe J; Alankarage D; Dunwoodie SL; Meunier FA; Francois M; Bulyk ML; Ramialison M; Harvey RP, 2025, NKX2-5 congenital heart disease mutations show diverse loss and gain of epigenomic, biochemical and chromatin search functions underpinning pathogenicity., http://dx.doi.org/10.1101/2025.06.20.659510

Wiszniak S; Alankarage D; Lohraseb I; Marchant C; Secker G; Parker W; Toubia J; White M; Piltz S; Tondl M; Giannoulatou E; Winlaw D; Blue GM; Tam PPL; Thomas P; Harvey N; Dunwoodie SL; Schwarz Q, 2025, Neural crest cell derived DKK1 modulates Wnt signalling in the second heart field to orchestrate cardiac outflow tract development, http://dx.doi.org/10.1101/2025.03.27.645622

, 2025, Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects, http://dx.doi.org/10.7554/eLife.97649

Bozon K; Cuny H; Sheng DZ; Martin EMMA; Sipka A; Young P; Humphreys DT; Dunwoodie SL, 2025, Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects, http://dx.doi.org/10.7554/elife.97649.2

Gudkov M; Thibaut L; Monger S; Das D; Congenital Heart Disease Synergy Study group ; Winlaw D; Dunwoodie S; Giannoulatou E, 2025, Benchmarking of variant pathogenicity prediction methods using a population genetics approach, http://dx.doi.org/10.1101/2025.03.16.643565

Bozon K; Cuny H; Sheng DZ; Martin EMMA; Young P; Humphreys DT; Dunwoodie SL, 2024, Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects, http://dx.doi.org/10.7554/elife.97649.1

Bozon K; Cuny H; Sheng D; Martin E; Sipka A; Young P; Humphreys D; Dunwoodie S, 2024, Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects, http://dx.doi.org/10.1101/2024.05.07.592899

Shen S; Werner T; Lukowski SW; Andersen S; Sun Y; Shim WJ; Mizikovsky D; Kobayashi S; Outhwaite J; Chiu HS; Chen X; Chapman G; Martin EMMA; Xia D; Pham D; Su Z; Kim D; Yang P; Tan MC; Sinniah E; Zhao Q; Negi S; Redd MA; Powell JE; Dunwoodie SL; Tam PPL; Bodén M; Ho JWK; Nguyen Q; Palpant NJ, 2022, A pluripotent stem cell atlas of multilineage differentiation revealsTMEM88as a developmental regulator of mammalian blood pressure, http://dx.doi.org/10.1101/2022.10.12.511862

Marjaneh MM; Kirk E; Patrick R; Alankerage D; Humphreys D; Del Monte-Nieto G; Cornejo-Paramo P; Janbandhu V; Doan T; Dunwoodie S; Wong E; Moran C; Martin ICA; Thomson P; Harvey R, 2022, Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line, http://dx.doi.org/10.1101/2022.10.31.514499

Page DJ; Miossec MJ; Williams SG; Fotiou E; Monaghan RM; Cordell HJ; Sutcliffe L; Topf A; Bourgey M; Bourque G; Eveleigh R; Dunwoodie SL; Winlaw DS; Bhattacharya S; Breckpot J; Devriendt K; Gewillig M; Brook D; Setchfield K; Bu’Lock FA; O’Sullivan J; Stuart G; Bezzina C; Mulder BJM; Postma AV; Bentham JR; Baron M; Bhaskar SS; Black GC; Newman WG; Hentges KE; Lathrop M; Santibanez-Koref M; Keavney BD, 2018, Deleterious genetic variants inNOTCH1are a major contributor to the incidence of non-syndromic Tetralogy of Fallot, http://dx.doi.org/10.1101/300905

Other

Saunders DN; Hird S; Withington SL; Dunwoodie SL; Henderson M; Biben C; Sutherland RL; Ormandy CJ; Watts CK, 2004, Edd, the murine ortholog of the hyperplastic discs (hyd) gene, isessential for yolk sac vascularization and chorioallantoic fusion (vol24, pg 7225, 2004), American Society for Microbiology, http://dx.doi.org/10.1128/MCB.24.20.9262.2004

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