By Professor Minoti Vivek Apte

Journal articles

Apte MV; Norton ID; Haber PS; Wilson JS, 1998, 'Alcohol and the pancreas (Review)', Addiction Biology, pp. 137 - 150

Norton ID; Apte MV; Lux O; Haber PS; Pirola RC; Wilson JS, 1998, 'Chronic ethanol administration causes oxidative stress in the rat pancreas', Journal of Laboratory and Clinical Medicine, 131, pp. 442 - 446, http://dx.doi.org/10.1016/S0022-2143(98)90145-7

Norton ID; Apte MV; Dixson H; Trent RJ; Haber PS; Pirola RC; Wilson JS, 1998, 'Cystic fibrosis genotypes and alcoholic pancreatitis', Journal of Gastroenterology and Hepatology, 13, pp. 496 - 499, http://dx.doi.org/10.1111/j.1440-1746.1998.tb00675.x

Norton ID; Apte MV; Haber PS; Mccaughan GW; Pirola RC; Wilson JS, 1998, 'Cytochrome P4502E1 is present in rat pancreas and is induced by chronic ethanol administration', Gut, 42, pp. 426 - 430, http://dx.doi.org/10.1136/gut.42.3.426

Haber PS; Norton ID; Norris MD; Apte MV; Pirola RC; Roberts-Thomson IC; Wilson JS, 1998, 'Is the 5T mutation in intron 8 of the cystic fibrosis gene associated with alcoholic pancreatitis?', Gastroenterology, 114, pp. A466 - A466, http://dx.doi.org/10.1016/s0016-5085(98)81884-2

Haber PS; Apte MV; Applegate TL; Norton ID; Korsten MA; Pirola R; Wilson JS, 1998, 'Metabolism of ethanol by rat pancreatic acinar cells', Journal of Laboratory and Clinical Medicine, 132, pp. 203 - 294, http://linkinghub.elsevier.com/retrieve/pii/S0022-2143(98)90042-7

Apte MV; Haber PS; Applegate TL; Norton ID; Mccaughan GW; Korsten MA; Pirola RC; Wilson JS, 1998, 'Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture', Gut, pp. 128 - 133, http://dx.doi.org/10.1136/gut.43.1.128

Keogh G; Haber PS; Apte MV; Moran CC; Mccaughan GW; Pirola RC; Wilson JS, 1998, 'Stellate Cells and Pancreatic Fibrosis', Australian and New Zealand Journal of Surgery, pp. A87

Apte MV; Norton ID; Haber PS; Applegate TL; Mccaughan GW; Korsten MA; Pirola RC; Wilson JS, 1998, 'The effect of ethanol on pancreatic enzymes - a dietary artefact?', Biochimica et Biophysica ACTA, 1379, pp. 314 - 324, http://dx.doi.org/10.1016/S0304-4165(97)00109-8

Apte MV; Wilson JS; Korsten MA, 1997, 'Alcohol-related pancreatic damage', Alcohol Research and Health, pp. 13 - 20

Apte MV; Norton ID; Haber PS; Mccaughan GW; Korsten MA; Pirola RC; Wilson JS, 1997, 'Chronic ethanol administration decreases rat pancreatic GP2 content', Biochimica et Biophysica ACTA, 1336, pp. 89 - 98, http://dx.doi.org/10.1016/S0304-4165(97)00015-9

Apte MV; Wilson JS; Mccaughan GW; Korsten MA; Pirola RC, 1996, 'Both ethanol and protein deficiency increase mRNA levels for pancreatic lithostathine', Life Sciences, 58, pp. 485 - 492, http://dx.doi.org/10.1016/0024-3205(95)02313-5

APTE M; NORTON I; HABER P; MCCAUGHAN G; KORSTEN M; PIROLA R; WILSON J, 1995, 'CHRONIC ETHANOL ADMINISTRATION INCREASES GENE-EXPRESSION OF GP2 IN RAT PANCREAS', GASTROENTEROLOGY, 108, pp. A342 - A342, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995QT86301355&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Apte MV; Wilson JS; Korsten MA; Mccaughan GW; Haber PS; Pirola RC, 1995, 'Effects of ethanol and protein deficiency on pancreatic digestive and lysosomal enzymes.', Gut, 36, pp. 287 - 293, http://dx.doi.org/10.1136/gut.36.2.287

Apte MV; Wilson JS; Mccaughan GW; Korsten MA; Haber PS; Norton ID; Pirola RC, 1995, 'Ethanol-induced alterations in messenger RNA levels correlate with glandular content of pancreatic enzymes', Journal of Laboratory and Clinical Medicine, 125, pp. 634 - 640

Haber PS; Wilson JS; Apte MV; Korsten MA; Pirola R, 1995, 'Individual susceptibility to alcoholic pancreatitis - still an enigma', Journal of Laboratory and Clinical Medicine, 125, pp. 305 - 312

APTE M; WILSON J; MCCAUGHAN G; KORSTEN M; HABER P; PIROLA R, 1994, 'ETHANOL-INDUCED ALTERATIONS IN GENE-EXPRESSION CORRELATE WITH GLANDULAR CONTENT OF PANCREATIC-ENZYMES', GASTROENTEROLOGY, 106, pp. A283 - A283, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NH90901123&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Haber PS; Wilson JS; Apte MV; Korsten MA; Pirola RC, 1994, 'Chronic ethanol consumption increases the fragility of rat pancreatic zymogen granules', Gut, 35, pp. 1474 - 1478, http://dx.doi.org/10.1136/gut.35.10.1474

Haber PS; Wilson JS; Apte MV; Hall W; Goumas K; Pirola RC, 1994, 'Lipid intolerance does not account for susceptibility to alcoholic and gallstone pancreatitis', Gastroenterology, 106, pp. 742 - 748, http://dx.doi.org/10.1016/0016-5085(94)90710-2

Apte MV; Norton ID; Wilson JS, 1994, 'Ethanol induced acinar cell injury', Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement., 2, pp. 365 - 368

APTE M; WILSON J; HABER P; KORSTEN M; MCCAUGHAN G; PIROLA R, 1993, 'ETHANOL AND DIETARY-PROTEIN DEFICIENCY ALTER GENE-EXPRESSION OF PANCREATIC DIGESTIVE ENZYMES', GASTROENTEROLOGY, 104, pp. A293 - A293, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993KX95701164&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Haber PS; Wilson JS; Apte MV; Pirola RC, 1993, 'Fatty acid ethyl esters increase rat pancreatic lysosomal fragility', Journal of Laboratory and Clinical Medicine, 121, pp. 759 - 764

Wilson JS; Apte MV; Thomas MC; Haber PS; Pirola RC, 1992, 'Effects of ethanol, acetaldehyde and cholesteryl esters on pancreatic lysosomes', Gut, 33, pp. 1099 - 1104, http://dx.doi.org/10.1136/gut.33.8.1099

Korsten MA; Wilson JS; Lieber CS, 1990, 'Interactive effect of dietary-protein and ethanol on rat pancreas - protein-synthesis and enzyme-secretion', Gastroenterology, 99, pp. 229 - 236, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1990DH80400031&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Wilson JS; Korsten MA; Apte MV; Thomas MC; Haber PS; Pirola RC, 1990, 'Both ethanol consumption and protein deficiency increase the fragility of pancreatic lysosomes', Journal of Laboratory and Clinical Medicine, 115, pp. 749 - 755

Bhagwandeen BS; Apte M; Manwarring L; Dickeson J, 1987, 'Endotoxin induced hepatic necrosis in rats on an alcohol diet', Journal of Pathology, 152, pp. 47 - 53, http://dx.doi.org/10.1002/path.1711520107

Bhagwandeen SB; Apte M; Manwarring L, 1987, 'Hepatitis provoked by endotoxin in rats on a prolonged ethanol diet', Medical Science Research, 15, pp. 303 - 304

Bhagwandeen SB; Apte M; Banathy LJ, 1985, 'Alcohol related hepatic lesions in young victims of road traffic accidents in Australia', IRCS Medical Science, 13, pp. 985 - 986

Apte M; Bhagwandeen SB; Husband AJ; Manwarring L, 1984, 'Circulating T-cells and T-cell subsets in rats on a prolonged ethanol diet', IRCS Medical Science, 12, pp. 902 - 903

Conference Papers

Hosen SMZ; Xu Z; Mekapogu AR; Perera C; Goldstein D; Pirola R; Wilson J; Buckley BJ; Ranson M; Apte M, 2023, 'Inhibition of urokinase plasminogen activator combined with gemcitabine enhances immune regulation and eradicates metastasis in pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 31 - 32

Sarkar R; Khan T; Binang H; Xu Z; Hosen SMZ; Mekapogu AR; Hoehn K; Horadagoda N; Pirola R; Wilson J; Perera C; Apte M, 2023, 'Pancreatic cancer-related diabetes: Impaired glucose tolerance and insulin signaling may drive progression of pancreatic intraepithelial neoplasms to overt cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 29 - 30

Xu Z; Rajan P; Lee B; Mekapogu AR; Perera C; Cohen-Hyams T; Killingsworth M; Husain S; Pirola R; Wilson J; Habtezion A; Pandol S; Apte M, 2023, 'Stellate cell and macrophage interaction may exacerbate alcoholic chronic pancreatitis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 38 - 39

Perera C; Hossain MJ; Mekapogu AR; Hosen SMZ; Rajan P; Xu Z; Greenfield J; Hoehn K; Horadagoda N; Chari S; Pirola R; Wilson J; Apte MV, 2022, 'Su1261: PANCREATIC CANCER-RELATED DIABETES: A HIGH FRUCTOSE DIET FED TO TRANSGENIC, KRASLSL-G12D/+; PDXCRE/+ (KC) MICE, IS ASSOCIATED WITH PANCREATIC STELLATE CELL ACTIVATION AND ACCELERATED CANCER PROGRESSION', in Gastroenterology, Elsevier BV, http://dx.doi.org/10.1016/s0016-5085(22)61328-3

Mekapogu A; Xu Z; Pothula S; Perera C; Pang T; Hosen SMS; Damalanka V; Mahoney V; Janekta J; Klampfer L; Goldstein D; Pirola R; Wilson J; Apte M; Perera C, 2021, 'Hepatocyte growth factor/c-MET inhibition plus chemotherapy improves tumor immunity and eliminates metastasis in pancreatic cancer', Virtual, presented at Australian Gastroenterology Week, Virtual, 10 August 2021

Mekapogu AR; Xu Z; Pothula S; Perera C; Pang T; Hosen SMZ; Damalanka VC; Mahoney M; Janetka JW; Klampfer L; Goldstein D; Pirola R; Wilson J; Apte MV, 2021, 'HEPATOCYTE GROWTH FACTOR/ C-MET PATHWAY INHIBITION COMBINED WITH CHEMOTHERAPY RETARDS PRECURSOR PANINS AND POTENTIATES LOCAL IMMUNITY IN A TRANSGENIC MODEL OF EARLY PANCREATIC CANCER', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, ELECTR NETWORK, pp. S45 - S45, presented at Society-for-Surgery-of-the-Alimentary-Tract Annual Meeting at Digestive Disease Week (DDW), ELECTR NETWORK, 21 May 2021 - 23 May 2021, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000649085000104&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Mekapogu AR; Xu Z; Pothula S; Perera C; Pang T; Hosen SMZ; Damalanka VC; Mahoney M; Janetka JW; Klampfer L; Goldstein D; Pirola R; Wilson J; Apte MV, 2021, '184 HEPATOCYTE GROWTH FACTOR/ C-MET PATHWAY INHIBITION COMBINED WITH CHEMOTHERAPY RETARDS PRECURSOR PANINS AND POTENTIATES LOCAL IMMUNITY IN A TRANSGENIC MODEL OF EARLY PANCREATIC CANCER', in Gastroenterology, Elsevier BV, pp. S - 45, http://dx.doi.org/10.1016/s0016-5085(21)00855-6

Hosen SMZ; Haar J; Xu Z; Perera C; Buckley BJ; Mekapogu AR; Pang TC; Pothula S; Ranson M; Goldstein D; Pirola R; Wilson J; Apte M, 2021, 'Targeting the urokinase plasminogen activator (uPA) pathway inhibits pancreatic cancer progression', in Pancreatology, Elsevier BV, pp. S73 - S73, http://dx.doi.org/10.1016/j.pan.2021.05.196

Main N; Yee C; Budzinska M; Cheng R; Au M; Tu T; Nicoll A; Apte M; Herath C; Shackel N, 2020, 'The balance between hepatocyte apoptosis and autophagy is mediated by the secretion of microRNA-192-5p', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 29 - 30, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000589476200039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'Pancreatic cancer-related diabetes: Do pancreatic stellate cell and cancer cell derived exosomes play a role?', in Pancreratology, presented at European Pancreatic Club

Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'I. Pancreatic Stellate Cell and Cancer Cell Derived Exosomes Impair Beta Cell Function: Implications for Pancreatic Cancer Related Diabetes', in Gastroenterology, Elsevier, Chicago, USA, presented at Digestive Disease Week, Chicago, USA, 02 May 2020, http://dx.doi.org/10.1016/S0016-5085(20)31245-2

Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte MV, 2020, 'PANCREATIC STELLATE CELL AND CANCER CELL DERIVED EXOSOMES IMPAIR BETA CELL FUNCTION: IMPLICATIONS FOR PANCREATIC CANCER RELATED DIABETES', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, TX, Austin, pp. S221 - S221, presented at Crohn's and Colitis Congress, TX, Austin, 23 January 2020 - 25 January 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000540349500565&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Pang T; Mekapogu AR; Xu Z; Pothula S; Goldstein D; Pirola R; Wilson J; Becker T; Apte M, 2020, 'Characterization of circulating pancreatic stellate cells in pancreatic cancer by single-cell transcriptomic analysis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 161 - 162

Mekapogu A; Xu Z; Pothula S; Perera C; Pang T; Hosen Z; Janetka J; Damalanka V; Mahoney M; Klampfer L; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'Inhibition of both the ligand and receptor of the hepatocyte growth factor/c-MET pathway, in combination with chemotherapy, retards progression of PanIN lesions in KPC mice', in Pancreatology, Elsevier BV, pp. S39 - S40, http://dx.doi.org/10.1016/j.pan.2020.07.049

Pang TC; Xu Z; Mekapogu AR; Pothula S; Goldstein D; Pirola R; Wilson J; Apte M, 2019, 'A Novel Adjuvant Treatment Approach in Pancreatic Cancer Via Hepatocyte Growth Factor (HGF)/c-MET Inhibition', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1504 - 1504, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000505712800433&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Xu Z; Pang T; Pothula S; Mekapogu A; Perera C; Murakami T; Goldstein D; Pirola R; Wilson J; Apte M, 2019, 'Inhibition of Hepatocyte Growth Factor (HGF) Signaling Pathway in Combination With Chemotherapy Reduces Tumour Burden in an Orthotopic Model of Advanced Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1551 - 1551, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000505712800617&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Geleta B; Park KC; Jansson PJ; Apte M; Richardson DR; Kovacevic Z, 2019, 'A novel therapeutic approach to inhibit the bidirectional oncogenic crosstalk between pancreatic cancer cells and the surrounding stroma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, MA, Boston, presented at AACR Special Conference on Pancreatic Cancer - Advances in Science and Clinical Care, MA, Boston, 06 September 2019 - 09 September 2019, http://dx.doi.org/10.1158/1538-7445.PANCA19-A16

Xu Z; Pang T; Pothula S; Mekapogu A; Perera C; Murakami T; Goldstein D; Pirola R; Wilson J; Apte M, 2019, 'Inhibition of hepatocyte growth factor signaling pathway in combination with chemotherapy reduces tumor burden in an orthotopic model of advanced pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 37 - 38, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000483843100057&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Pang T; Xu Z; Mekapogu A; Pothula S; Goldstein D; Pirola R; Wilson J; Apte M, 2019, 'Establishment of a novel adjuvant model of orthotopic pancreatic cancer: Effects of HGF-cMET inhibition on disease progression', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 35 - 36

Xu Z; Buckley BJ; Pothula S; Pang T; Goldstein D; Pirola RC; Wilson JS; Kelso MJ; Ranson M; Apte MV, 2018, 'Amiloride Analogues as Inhibitors of Human Urokinase Plasminogen Activator and Anti-Pancreatic Cancer Agents', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1434 - 1434, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449304600277&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Pang T; Xu Z; Pothula S; Yang MH; Becker T; Goldstein D; Heeschen C; Pirola R; Wilson J; Apte MV, 2018, 'WORLD-FIRST IDENTIFICATION OF CIRCULATING PANCREATIC STELLATE CELLS IN METASTATIC PANCREATIC CANCER', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. S114 - S114, presented at Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week, DC, Washington, 02 June 2018 - 05 June 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000450011100327&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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