By Professor Minoti Vivek Apte

Book Chapters

Apte MV; Pirola RC; Wilson JS, 2023, 'Fibrogenesis in the Pancreas', in , Wiley, pp. 86 - 97, http://dx.doi.org/10.1002/9781119876007.ch9

Pang T; Xu Z; Perera C; Apte MV, 2023, 'Tumor Microenvironment', in , Wiley, pp. 942 - 950, http://dx.doi.org/10.1002/9781119876007.ch123

Wilson JS; Pirola RC; Apte MV, 2023, 'Epidemiology and Etiology of Alcohol-Induced Pancreatitis', in Pancreas an Integrated Textbook of Basic Science Medicine and Surgery Fourth Edition, pp. 107 - 118

Apte MV; Pirola RC; Wilson JS, 2023, 'Fibrogenesis in the Pancreas: The Role of Pancreatic Stellate Cells', in Pancreas an Integrated Textbook of Basic Science Medicine and Surgery Fourth Edition, pp. 86 - 97

Pang T; Xu Z; Perera C; Apte MV, 2023, 'Tumor Microenvironment: Immune Cells and Immunosuppressive Functions of Carcinoma-associated Fibroblasts and Macrophages', in The Pancreas: an Integrated Textbook of Basic Science, Medicine, and Surgery, Fourth Edition, Wiley, pp. 942 - 950, http://dx.doi.org/10.1002/9781119876007.ch123

Wilson JS; Pirola RC; Apte MV, 2021, 'Alcoholic Chronic Pancreatitis and the Impact of Alcohol and Smoking Cessation in Chronic Pancreatitis', in Clinical Pancreatology for Practising Gastroenterologists and Surgeons Second Edition, pp. 185 - 192, http://dx.doi.org/10.1002/9781119570097.ch25

Wilson J; Pirola R; Apte M, 2018, 'Epidemiology and Etiology of Alcohol‐Induced Pancreatitis', in The Pancreas An Integrated Textbook of Basic Science, Medicine, and Surgery, John Wiley & Sons, pp. 135 - 145

Apte M; Pirola R; Wilson J, 2018, 'Fibrogenesis of the pancreas - Role of stellate cells', in The Pancreas An Integrated Textbook of Basic Science, Medicine, and Surgery, John Wiley & Sons, pp. 106 - 116

Apte MV; Pirola RC; Wilson JS, 2018, 'Fibrogenesis in the Pancreas', in , Wiley, pp. 106 - 116, http://dx.doi.org/10.1002/9781119188421.ch10

Wilson JS; Pirola RC; Apte MV, 2018, 'Epidemiology and Etiology of Alcohol-Induced Pancreatitis', in Pancreas an Integrated Textbook of Basic Science Medicine and Surgery Third Edition, pp. 133 - 145, http://dx.doi.org/10.1002/9781119188421.ch13

Apte MV; Xu Z; Pirola R; Wilson JS, 2017, 'Pancreatic Stellate Cells: What do they tell us about chronic pancreatitis?', in Pancreatitis Medical and Surgical Management, John Wiley & Sons, pp. 143 - 151

Apte MV; Xu Z; Pirola RC; Wilson JS, 2017, 'Part C: Pancreatic stellate cells: What do they tell us about chronic pancreatitis?', in Pancreatitis Medical and Surgical Management, pp. 143 - 151

Apte M; Pirola R; Wilson JS, 2016, 'Alcohol and the Pancreas', in Pancreatitis, University of Michigan Library, pp. 133 - 146

Apte MV; Pirola RC; Wilson JS, 2015, 'Chapter 16 - Pancreatic Stellate Cells', in Ghandi C; Pinzani M (ed.), Stellate Cells in Health and Disease, Academic Press (imprint of Elsevier), London, pp. 271 - 306, http://dx.doi.org/10.1016/B978-0-12-800134-9.00016-6

Apte M, 2012, 'Preface', in , pp. 179, http://dx.doi.org/10.1016/j.pan.2012.05.010

Apte MV; Pirola RM; Wilson JS, 2012, 'Stellate Cells and the Pancreas', in Nageshwar Reddy D (ed.), Recent Advances in the Pancreas, Reed Elsevier, India, pp. 54 - 87

Apte MV; Pirola RC; Wilson JS, 2009, 'Etiopathogenesis and epidemiology of alcohol-induced acute pancreatitis', in The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery: Second Edition, Blackwell Publishing Ltd., pp. 143 - 153, http://dx.doi.org/10.1002/9781444300123.ch13

Apte MV; Pirola RC; Wilson JS, 2008, 'Etiopathogenesis and epidemiology of alcohol-induced acute pancreatitis', in Beger H-G; Buchler M; Kozarek R; Lerch M; Neoptolemos J; Warshaw A; Whitcomb D; Shiratori K (ed.), Pancreas : An integrated textbook of basic science, medicine and surgery, Blackwell Publishing, pp. 145 - 153

Wilson JS; Apte MV, 2005, 'The importance of keeping in touch: regulation of cell-cell contact in the exocrine pancreas', in Gut, B M J Publishing Group, London, England, pp. 1358 - 1359

Apte M; Wilson J, 2004, 'What’s New in Pancreatic Stellate Cell Biology?', in Pancreatic Disease, Springer London, pp. 203 - 225, http://dx.doi.org/10.1007/978-1-85233-904-3_17

Apte MV; Wilson JS, 2003, 'Chronic pancreatitis: How and why is fibrosis initiated?', in Permert J; Herrington M; Te A (ed.), Controversies in Pancreatology, Carlsson Communications, Stockholm, AB, pp. 80 - 92

Apte MV; Wilson JS, 2001, 'Experimental models of Pancreatic fibrogenesis and the role of stellate cell', in Buchler M; Friess H; Uhl W; Malfertheiner P (ed.), Experimental models of Pancreatic fibrogenesis and the role of stellate cell, Blackwell Science, Heidelberg, pp. 113 - 133

Journal articles

Lin Z; Pandol S; Apte M; Jiang Y, 2025, 'Navigating chronic pancreatitis pain: a pathophysiological and therapeutic overview', Frontiers in Physiology, 16, http://dx.doi.org/10.3389/fphys.2025.1622845

Jeon CY; Ye Y; Papachristou GI; Buxbaum JL; Pisegna JR; Cherpitel CJ; Adeniran EA; Apte M; Chang E; Dasyam AK; Jalluri GD; Lansky CA; Lugea A; Shah ZK; Waldron RT; Pandol SJ; Yadav D, 2025, 'Differential impact of recent heavy drinking on first and recurrent acute pancreatitis', Alcohol Clinical and Experimental Research, 49, pp. 1053 - 1063, http://dx.doi.org/10.1111/acer.70030

Apte M, 2025, 'PDAC: advances in tumour microenvironment, microbiome and AI: Pancreatic cancer in 2024', Nature Reviews Gastroenterology and Hepatology, 22, pp. 96 - 97, http://dx.doi.org/10.1038/s41575-024-01030-y

Porter G; Norris MD; Apte M; Merlot AM, 2025, 'Spatial profiling of endoplasmic reticulum stress markers in tumor associated cells predicts patient outcomes in pancreatic cancer', Neoplasia United States, 60, http://dx.doi.org/10.1016/j.neo.2024.101115

Binang H; Sarkar R; Wong W; Hardikar A; Xu Z; Rajan P; Pirola R; Wilson J; Perera C; Apte M, 2025, 'Tu1376: PICALM IN PANCREATIC STELLATE CELL AND CANCER CELL COCULTURE-DERIVED EXOSOMAL CARGO – MEDIATOR OF PANCREATIC CANCER-RELATED DIABETES?', Gastroenterology, 169, http://dx.doi.org/10.1016/s0016-5085(25)04128-9

Perera CJ; Hosen SZ; Khan T; Fang H; Mekapogu AR; Xu Z; Falasca M; Chari ST; Wilson JS; Pirola R; Greening DW; Apte MV, 2024, 'Proteomic profiling of small extracellular vesicles derived from mouse pancreatic cancer and stellate cells: Role in pancreatic cancer', Proteomics, 24, http://dx.doi.org/10.1002/pmic.202300067

Turner RC; Salomoni S; Neale RE; Neil A; Barreto SG; Ooi CY; Croagh D; Wilson JS; Pang T; Apte M, 2024, 'The epidemiology of acute pancreatitis in Tasmania over a 12-year period: Is this a disease of disadvantage?', Pancreatology, 24, pp. 522 - 527, http://dx.doi.org/10.1016/j.pan.2024.04.010

Apte M, 2023, 'A journey to and with the stars: The pancreatic stellate cell story', Pancreatology, 23, pp. 893 - 899, http://dx.doi.org/10.1016/j.pan.2023.10.024

Sarkar R; Xu Z; Perera CJ; Apte MV, 2023, 'Emerging role of pancreatic stellate cell-derived extracellular vesicles in pancreatic cancer', Seminars in Cancer Biology, 93, pp. 114 - 122, http://dx.doi.org/10.1016/j.semcancer.2023.05.007

Mastracci TL; Apte M; Amundadottir LT; Alvarsson A; Artandi S; Bellin MD; Bernal-Mizrachi E; Caicedo A; Campbell-Thompson M; Cruz-Monserrate Z; Ouaamari AE; Gaulton KJ; Geisz A; Goodarzi MO; Hara M; Hull-Meichle RL; Kleger A; Klein AP; Kopp JL; Kulkarni RN; Muzumdar MD; Naren AP; Oakes SA; Olesen SS; Phelps EA; Powers AC; Stabler CL; Tirkes T; Whitcomb DC; Yadav D; Yong J; Zaghloul NA; Pandol SJ; Sander M, 2023, 'Erratum to: Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings (Diabetes 2023; 72: 433–448)', Diabetes, 72, pp. 1173, http://dx.doi.org/10.2337/db23-er08

Mekapogu AR; Xu Z; Pothula S; Perera C; Pang T; Hosen SMZ; Damalanka V; Janetka J; Goldstein D; Pirola R; Wilson J; Apte M, 2023, 'HGF/c-Met pathway inhibition combined with chemotherapy increases cytotoxic T-cell infiltration and inhibits pancreatic tumour growth and metastasis', Cancer Letters, 568, http://dx.doi.org/10.1016/j.canlet.2023.216286

Binang HB; Perera CJ; Apte MV, 2023, 'Role of Pancreatic Tumour-Derived Exosomes and Their Cargo in Pancreatic Cancer-Related Diabetes', International Journal of Molecular Sciences, 24, pp. 10203, http://dx.doi.org/10.3390/ijms241210203

Mastracci TL; Apte M; Amundadottir LT; Alvarsson A; Artandi S; Bellin MD; Bernal-Mizrachi E; Caicedo A; Campbell-Thompson M; Cruz-Monserrate Z; Ouaamari AE; Gaulton KJ; Geisz A; Goodarzi MO; Hara M; Hull-Meichle RL; Kleger A; Klein AP; Kopp JL; Kulkarni RN; Muzumdar MD; Naren AP; Oakes SA; Olesen SS; Phelps EA; Powers AC; Stabler CL; Tirkes T; Whitcomb DC; Yadav D; Yong J; Zaghloul NA; Pandol SJ; Sander M, 2023, 'Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings', Diabetes, 72, pp. 433 - 448, http://dx.doi.org/10.2337/db22-0942

Hosen SMZ; Uddin MN; Xu Z; Buckley BJ; Perera C; Pang TCY; Mekapogu AR; Moni MA; Notta F; Gallinger S; Pirola R; Wilson J; Ranson M; Goldstein D; Apte M, 2022, 'Metastatic phenotype and immunosuppressive tumour microenvironment in pancreatic ductal adenocarcinoma: Key role of the urokinase plasminogen activator (PLAU)', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.1060957

Mastracci TL; Apte M; Amundadottir LT; Alvarsson A; Artandi S; Bellin MD; Bernal-Mizrachi E; Caicedo A; Campbell-Thompson M; Cruz-Monserrate Z; El Ouaamari A; Gaulton KJ; Geisz A; Goodarzi MO; Hara M; Hull-Meichle RL; Kleger A; Klein AP; Kopp JL; Kulkarni RN; Muzumdar MD; Naren AP; Oakes SA; Olesen SS; Phelps EA; Powers AC; Stabler CL; Tirkes T; Whitcomb DC; Yadav D; Yong J; Zaghloul NA; Sander M; Pandol SJ, 2022, 'Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings', Pancreas, 51, pp. 1061 - 1073, http://dx.doi.org/10.1097/MPA.0000000000002170

Channon LM; Tyma VM; Xu Z; Greening DW; Wilson JS; Perera CJ; Apte MV, 2022, 'Small extracellular vesicles (exosomes) and their cargo in pancreatic cancer: Key roles in the hallmarks of cancer', Biochimica Et Biophysica Acta Reviews on Cancer, 1877, pp. 188728, http://dx.doi.org/10.1016/j.bbcan.2022.188728

Geleta B; Tout FS; Lim SC; Sahni S; Jansson PJ; Apte MV; Richardson DR; Kovacevic Z, 2022, 'Targeting Wnt/tenascin C-mediated cross talk between pancreatic cancer cells and stellate cells via activation of the metastasis suppressor NDRG1', Journal of Biological Chemistry, 298, http://dx.doi.org/10.1016/j.jbc.2022.101608

Perera CJ; Falasca M; Chari ST; Greenfield JR; Xu Z; Pirola RC; Wilson JS; Apte MV, 2021, 'Role of pancreatic stellate cell-derived exosomes in pancreatic cancer-related diabetes: A novel hypothesis', Cancers, 13, pp. 5224, http://dx.doi.org/10.3390/cancers13205224

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496

Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker T; Corley S; Wilkins MR; Goldstein D; Pirola R; Wilson J; Apte M, 2021, 'Hgf/c-met inhibition as adjuvant therapy improves outcomes in an orthotopic mouse model of pancreatic cancer', Cancers, 13, pp. 2763, http://dx.doi.org/10.3390/cancers13112763

Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z, 2021, 'Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma', FASEB Journal, 35, http://dx.doi.org/10.1096/fj.202002279R

Pang TCY; Po JW; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2021, 'Circulating tumour cells in pancreatic cancer: A systematic review and meta-analysis of clinicopathological implications', Pancreatology, 21, pp. 103 - 114, http://dx.doi.org/10.1016/j.pan.2020.11.022

Pothula SP; Xu Z; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Targeting hgf/c-met axis in pancreatic cancer', International Journal of Molecular Sciences, 21, pp. 1 - 18, http://dx.doi.org/10.3390/ijms21239170

Xu Z; Pothula S; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Reply letter to comments on: Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis', British Journal of Cancer, 123, pp. 1466, http://dx.doi.org/10.1038/s41416-020-1004-6

Santoso F, 2020, 'Message from rector', ACM International Conference Proceeding Series

Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'An Orthotopic Resectional Mouse Model of Pancreatic Cancer', Journal of Visualized Experiments, http://dx.doi.org/10.3791/61726-v

Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'An orthotopic resectional mouse model of pancreatic cancer', Journal of Visualized Experiments, 2020, pp. 1 - 13, http://dx.doi.org/10.3791/61726

Xu Z; Pang TCY; Liu AC; Pothula SP; Mekapogu AR; Perera CJ; Murakami T; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis', British Journal of Cancer, 122, pp. 1486 - 1495, http://dx.doi.org/10.1038/s41416-020-0782-1

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