By Emeritus Professor William Ledger

Journal articles

Costello MF; Garad RM; Hart R; Homer H; Johnson L; Jordan C; Mocanu E; Qiao J; Rombauts L; Teede HJ; Vanky E; Venetis CA; Ledger WL, 2019, 'A Review of Second- and Third-line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome', Medical Sciences Basel Switzerland, 7, http://dx.doi.org/10.3390/medsci7070075

Anazodo A; Ledger W, 2019, 'Assessing and Supporting Adolescent Boys Having Fertility Preservation', In: Woodruff T., Shah D., Vitek W. (eds) Textbook of Oncofertility Research and Practice., pp. 507 - 512, http://dx.doi.org/10.1007/978-3-030-02868-8_53

Rodriguez Paris V; Solon-Biet S; Edwards M; Cox M; Ledger W; Gilchrist R; Simpson S; Handelsman D; Walters K, 2019, 'MON-231 Dietary Interventions Can Ameliorate Polycystic Ovary Syndrome (PCOS) Traits in a PCOS Mouse Model', Journal of the Endocrine Society, 3, http://dx.doi.org/10.1210/js.2019-mon-231

Aflatounian A; Edwards M; Gilchrist R; Bertoldo M; Ledger W; Handelsman D; Walters K, 2019, 'OR08-2 Androgen Receptor- Vs Estrogen Receptor-Mediated Actions in the Development of Distinct Clinical Polycystic Ovary Syndrome (PCOS) Phenotypes', Journal of the Endocrine Society, 3, http://dx.doi.org/10.1210/js.2019-or08-2

Bertoldo MJ; Caldwell ASL; Riepsamen AH; Lin D; Gonzalez MB; Robker RL; Ledger WL; Gilchrist RB; Handelsman DJ; Walters KA, 2019, 'A hyperandrogenic environment causes intrinsic defects that are detrimental to follicular dynamics in a PCOS mouse model', Endocrinology, 160, pp. 699 - 715, http://dx.doi.org/10.1210/en.2018-00966

Richani D; Constance K; Lien S; Agapiou D; Stocker WA; Hedger MP; Ledger WL; Thompson JG; Robertson DM; Mottershead DG; Walton KL; Harrison CA; Gilchrist RB, 2019, 'Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro', Endocrinology, 160, pp. 853 - 862, http://dx.doi.org/10.1210/en.2018-01026

Weddell S; Jones GL; Duffy S; Hogg C; Johnson S; Ledger W, 2019, 'Home ovulation test use and stress during subfertility evaluation: Subarm of a randomized controlled trial', Women S Health, 15, http://dx.doi.org/10.1177/1745506519838363

Crawford GE; Ledger WL, 2019, 'In vitro fertilisation/intracytoplasmic sperm injection beyond 2020', BJOG an International Journal of Obstetrics and Gynaecology, 126, pp. 237 - 243, http://dx.doi.org/10.1111/1471-0528.15526

Hardy T; Ledger W; Scott H, 2019, '28. KARYOMAPPING USING WHOLE GENOME SEQUENCING DATA: PRECLINICAL VALIDATION OF A PERSONALISED APPROACH TO PGT-M', Reproductive BioMedicine Online, 39, pp. e43 - e44, http://dx.doi.org/10.1016/j.rbmo.2019.04.081

Walters KA; Gilchrist RB; Ledger WL; Teede HJ; Handelsman DJ; Campbell RE, 2018, 'New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins', Trends in Endocrinology and Metabolism, 29, pp. 841 - 852, http://dx.doi.org/10.1016/j.tem.2018.08.005

Vogt KS; Hughes J; Wilkinson A; Mahmoodi N; Skull J; Wood H; McDougall S; Slade P; Greenfield DM; Pacey A; Ledger W; Jones GL, 2018, 'Preserving fertility in women with cancer (PreFer): Decision-making and patient-reported outcomes in women offered egg and embryo freezing prior to cancer treatment', Psycho Oncology, 27, pp. 2725 - 2732, http://dx.doi.org/10.1002/pon.4866

Anazodo A; Paula L; Logan S; Saunders C; Travaglia J; Gerstl B; Bradford N; Cohn R; Birdsall M; Barr R; Suzuki N; Seido T; Marinho R; Xiao S; Qiang-Hua C; Mahajan N; Patil M; Gunasheela D; Smith K; Sender L; Melo C; Almeida-Santos T; Salama M; Appiah L; Su I; Lane S; Woodruff T; Pacey A; Anderson RA; Shenfield F; Ledger W; Sullivan E, 2018, 'How can we improve oncofertility care for patients? A systematic scoping review of current international practice and models of care.', Human Reproduction Update, 25, pp. 159 - 179, http://dx.doi.org/10.1093/humupd/dmy038

Ledger W, 2018, 'Preface – Vol. 53', Best Practice and Research Clinical Obstetrics and Gynaecology, 53, pp. 1 - 2, http://dx.doi.org/10.1016/j.bpobgyn.2018.10.005

Deans R; Vancaillie T; Ledger W; Liu J; Abbott JA, 2018, 'Live birth rate and obstetric complications following the hysteroscopic management of intrauterine adhesions including Asherman syndrome', Human Reproduction, 33, pp. 1847 - 1853, http://dx.doi.org/10.1093/humrep/dey237

Bertoldo MJ; Walters KA; Ledger WL; Gilchrist RB; Mermillod P; Locatelli Y, 2018, 'In-vitro regulation of primordial follicle activation: challenges for fertility preservation strategies', Reproductive Biomedicine Online, 36, pp. 491 - 499, http://dx.doi.org/10.1016/j.rbmo.2018.01.014

Storr A; Venetis C; Cooke S; Kilani S; Ledger W, 2018, 'Time-lapse algorithms and morphological selection of day-5 embryos for transfer: a preclinical validation study', Fertility and Sterility, 109, pp. 276 - 283.e3, http://dx.doi.org/10.1016/j.fertnstert.2017.10.036

Ledger WL, 2017, 'The HFEA should be regulating add-on treatments for IVF/ICSI', BJOG an International Journal of Obstetrics and Gynaecology, 124, pp. 1850, http://dx.doi.org/10.1111/1471-0528.14670

Jones G; Hughes J; Mahmoodi N; Smith E; Skull J; Ledger W, 2017, 'What factors hinder the decision-making process for women with cancer and contemplating fertility preservation treatment?', Human Reproduction Update, 23, pp. 433 - 457, http://dx.doi.org/10.1093/humupd/dmx009

McCredie S; Ledger W; Venetis CA, 2017, 'Anti-Müllerian hormone kinetics in pregnancy and post-partum: a systematic review', Reproductive Biomedicine Online, 34, pp. 522 - 533, http://dx.doi.org/10.1016/j.rbmo.2017.02.005

Rodgers RJ; Reid GD; Koch J; Deans R; Ledger WL; Friedlander M; Gilchrist RB; Walters KA; Abbott JA, 2017, 'The safety and efficacy of controlled ovarian hyperstimulation for fertility preservation in women with early breast cancer: A systematic review', Human Reproduction, 32, pp. 1033 - 1045, http://dx.doi.org/10.1093/humrep/dex027

Patanwala IY; Lamvu G; Ledger WJ; Witzeman K; Marvel R; Rapkin A; Bongiovanni AM; Feranec J; Witkin SS, 2017, 'Catechol-O-methyltransferase gene polymorphism and vulvar pain in women with vulvodynia', American Journal of Obstetrics and Gynecology, 216, pp. 395 - 395.e6, http://dx.doi.org/10.1016/j.ajog.2016.10.020

Ledger WL, 2017, 'A history of mental illness, but not of conception with assisted reproductive technology, puts patients at increased risk of severe postnatal depression', BJOG an International Journal of Obstetrics and Gynaecology, 124, pp. 443, http://dx.doi.org/10.1111/1471-0528.13792

Storr A; Venetis CA; Cooke S; Kilani S; Ledger W, 2017, 'Inter-observer and intra-observer agreement between embryologists during selection of a single Day 5 embryo for transfer: A multicenter study', Human Reproduction, 32, pp. 307 - 314, http://dx.doi.org/10.1093/humrep/dew330

Nasioudis D; Linhares IM; Ledger WJ; Witkin SS, 2017, 'Bacterial vaginosis: a critical analysis of current knowledge', BJOG an International Journal of Obstetrics and Gynaecology, 124, pp. 61 - 69, http://dx.doi.org/10.1111/1471-0528.14209

Chambers GM; Wand H; Macaldowie A; Chapman MG; Farquhar CM; Bowman M; Molloy D; Ledger W, 2016, 'Population trends and live birth rates associated with common ART treatment strategies', Human Reproduction, 31, pp. 2632 - 2641, http://dx.doi.org/10.1093/humrep/dew232

Anazodo AC; Stern CJ; Mclachlan RI; Gerstl B; Agresta F; Cohn RJ; Jayasinghe Y; Wakefield CE; Daly G; Chan D; Gilbert L; Kemertzis M; Orme LM; Wand H; Viney R; Gillam L; Deans R; Jetti M; Wu J; Chapman M; Ledger W; Sullivan EA, 2016, 'A study protocol for the australasian oncofertility registry: Monitoring referral patterns and the uptake, quality, and complications of fertility preservation strategies in Australia and New Zealand', Journal of Adolescent and Young Adult Oncology, 5, pp. 215 - 225, http://dx.doi.org/10.1089/jayao.2015.0062

Anazodo AC; Gerstl B; Stern CJ; Mclachlan RI; Agresta F; Jayasinghe Y; Cohn RJ; Wakefield CE; Chapman M; Ledger W; Sullivan EA, 2016, 'Utilizing the experience of consumers in consultation to develop the australasian oncofertility consortium charter', Journal of Adolescent and Young Adult Oncology, 5, pp. 232 - 239, http://dx.doi.org/10.1089/jayao.2015.0056

McCullough K; Ledger W, 2016, 'Anti-Müllerian hormone is all you need: An assisted reproductive technology perspective in diagnosing polycystic ovary syndrome', Women S Health, 12, pp. 263 - 265, http://dx.doi.org/10.2217/whe-2016-0005

Wang X; Gook DA; Walters KA; Anazodo A; Ledger WL; Gilchrist RB, 2016, 'Improving fertility preservation for girls and women by coupling oocyte in vitro maturation with existing strategies', Women S Health, 12, pp. 275 - 278, http://dx.doi.org/10.2217/whe-2016-0019

Robertson DM; Gilchrist RB; Ledger WL; Baerwald A, 2016, 'Random start or emergency IVF/in vitro maturation: A new rapid approach to fertility preservation', Women S Health, 12, pp. 339 - 349, http://dx.doi.org/10.2217/whe-2015-0001

Lim HJ; Ledger W, 2016, 'Targeted therapy in ovarian cancer', Women S Health, 12, pp. 363 - 378, http://dx.doi.org/10.2217/whe.16.4

Jones GL; Jacques RM; Thompson J; Wood HJ; Hughes J; Ledger W; Alazzam M; Radley SC; Tidy JA, 2016, 'The impact of surgery for vulval cancer upon health-related quality of life and pelvic floor outcomes during the first year of treatment: a longitudinal, mixed methods study', Psycho Oncology, pp. 656 - 662, http://dx.doi.org/10.1002/pon.3992

Ledger W; Johnson MH, 2016, 'One plus one equals two: Why fetal reduction is always a second-best solution', Reproductive Biomedicine Online, 32, pp. 467 - 468, http://dx.doi.org/10.1016/j.rbmo.2016.03.002

Ledger WL; Turner MJ, 2016, 'Implementation of the findings of a national enquiry into the misdiagnosis of miscarriage in the Republic of Ireland: impact on quality of clinical care', Fertility and sterility, 105, pp. 417 - 422, http://dx.doi.org/10.1016/j.fertnstert.2015.11.002

Ledger WL; Turner MJ, 2016, 'Implementation of the findings of a national enquiry into the misdiagnosis of miscarriage in the Republic of Ireland: impact on quality of clinical care', Fertility and Sterility, 105, pp. 417 - 422, http://dx.doi.org/10.1016/j.fertnstert.2015.11.002

Ledger W, 2016, 'A history of mental illness, but not of conception with assisted reproductive technology, puts patients at increased risk of severe postnatal depression', BJOG: An International Journal of Obstetrics and Gynaecology, http://dx.doi.org/10.1111/1471-0528.13792

Ledger WL, 2016, 'Superfertility is more prevalent in obese women with recurrent early pregnancy miscarriage', BJOG an International Journal of Obstetrics and Gynaecology, 123, pp. 223, http://dx.doi.org/10.1111/1471-0528.13815

Jones G; Carlton J; Weddell S; Johnson S; Ledger WL, 2015, 'Women's experiences of ovulation testing: A qualitative analysis', Reproductive Health, 12, http://dx.doi.org/10.1186/s12978-015-0103-y

Beghini J; Linhares IM; Giraldo PC; Ledger WJ; Witkin SS, 2015, 'Differential expression of lactic acid isomers, extracellular matrix metalloproteinase inducer, and matrix metalloproteinase-8 in vaginal fluid from women with vaginal disorders', BJOG an International Journal of Obstetrics and Gynaecology, 122, pp. 1580 - 1585, http://dx.doi.org/10.1111/1471-0528.13072

Ledger W, 2015, 'Letter to the editor', Journal of Assisted Reproduction and Genetics, 32, pp. 1161, http://dx.doi.org/10.1007/s10815-015-0526-y

Storr A; Venetis CA; Cooke S; Susetio D; Kilani S; Ledger W, 2015, 'Morphokinetic parameters using time-lapse technology and day 5 embryo quality: a prospective cohort study', Journal of Assisted Reproduction and Genetics, 32, pp. 1151 - 1160, http://dx.doi.org/10.1007/s10815-015-0534-y

Coughlan C; Clarke H; Cutting R; Saxton J; Waite S; Ledger W; Li T; Pacey AA, 2015, 'Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage', Asian Journal of Andrology, 17, pp. 681 - 685, http://dx.doi.org/10.4103/1008-682X.144946

Riepsamen A; Wu L; Lau L; Listijono D; Ledger W; Sinclair DA; Homer H, 2015, 'Erratum: Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes (PLoS ONE (2015) 10:5 (e0126194) DOI:10.1371/journal.pone.0126194)', Plos One, 10, pp. e0126194, http://dx.doi.org/10.1371/journal.pone.0126194

Riepsamen A; Wu L; Lau L; Listijono D; Ledger W; Sinclair D; Homer H, 2015, 'Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes', Plos One, 10, pp. e0130058, http://dx.doi.org/10.1371/journal.pone.0130058

Aitchison LP; Flint J; Nesbitt-Hawes E; Ledger W; Abbott J, 2015, 'a feasibility study determining surgical ergonomics in a live surgical setting', Journal of Minimally Invasive Gynecology, 22, pp. 626 - 630, http://dx.doi.org/10.1016/j.jmig.2015.01.022

Refaat B; Dalton E; Ledger WL, 2015, 'Ectopic pregnancy secondary to in vitro fertilisation-embryo transfer: Pathogenic mechanisms and management strategies', Reproductive Biology and Endocrinology, 13, http://dx.doi.org/10.1186/s12958-015-0025-0

Scholten I; Chambers GM; Van Loendersloot L; Van Der Veen F; Repping S; Gianotten J; Hompes PGA; Ledger W; Mol BWJ, 2015, 'Impact of assisted reproductive technology on the incidence of multiple-gestation infants: A population perspective', Fertility and Sterility, 103, pp. 179 - 183, http://dx.doi.org/10.1016/j.fertnstert.2014.09.033

Nesbitt-Hawes EM; Campbell N; Maley PE; Won H; Hooshmand D; Henry A; Ledger W; Abbott JA, 2015, 'The Surgical Treatment of Severe Endometriosis Positively Affects the Chance of Natural or Assisted Pregnancy Postoperatively', Biomed Research International, 2015, pp. 438790, http://dx.doi.org/10.1155/2015/438790

Atkinson P; Koch J; Ledger WL, 2014, 'GnRH agonist trigger and a freeze-all strategy to prevent ovarian hyperstimulation syndrome: A retrospective study of OHSS risk and pregnancy rates', Australian and New Zealand Journal of Obstetrics and Gynaecology, 54, pp. 581 - 585, http://dx.doi.org/10.1111/ajo.12277

Metwally M; Preece R; Thomas J; Ledger W; Li TC, 2014, 'A proteomic analysis of the endometrium in obese and overweight women with recurrent miscarriage: Preliminary evidence for an endometrial defect', Reproductive Biology and Endocrinology, 12, http://dx.doi.org/10.1186/1477-7827-12-75

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