By Emeritus Professor William Ledger

Journal articles

Sandhu S; Hickey M; Lew R; Hammarberg K; Braat S; Agresta F; Parle A; Allingham C; Ledger W; Fisher J; Johnson L; Michelmore J; Summers F; Hart R; Norman RJ; Lieberman D; Anderson RA; Peate M, 2023, 'The development and phase 1 evaluation of a Decision Aid for elective egg freezing', BMC Medical Informatics and Decision Making, 23, http://dx.doi.org/10.1186/s12911-023-02178-4

Mihalas BP; Frost ER; Kadam KM; Sucquart IE; Sirigeri P; Ledger WL; Gilchrist RB, 2023, 'A strong foundation for the next generation', Molecular Reproduction and Development, 90, pp. 773, http://dx.doi.org/10.1002/mrd.23709

Venetis C; Choi SKY; Jorm L; Zhang X; Ledger W; Lui K; Havard A; Chapman M; Norman RJ; Chambers GM, 2023, 'Risk for Congenital Anomalies in Children Conceived With Medically Assisted Fertility Treatment', Annals of Internal Medicine, 176, pp. 1308 - 1320, http://dx.doi.org/10.7326/M23-0872

Strout N; Pasic L; Hicks C; Chua XY; Tashvighi N; Butler P; Liu Z; El-Assaad F; Holmes E; Susic D; Samaras K; Craig ME; Davis GK; Henry A; Ledger WL; El-Omar EM, 2023, 'The MothersBabies Study, an Australian Prospective Cohort Study Analyzing the Microbiome in the Preconception and Perinatal Period to Determine Risk of Adverse Pregnancy, Postpartum, and Child-Related Health Outcomes: Study Protocol', International Journal of Environmental Research and Public Health, 20, pp. 6736, http://dx.doi.org/10.3390/ijerph20186736

Sandhu S; Hickey M; Braat S; Hammarberg K; Lew R; Fisher J; Ledger W; Peate M; Agresta F; Lieberman D; Anderson R; Norman R; Hart R; Johnson L; Michelmore J; Parle A; Summers F; Allingham C, 2023, 'Information and decision support needs: A survey of women interested in receiving planned oocyte cryopreservation information', Journal of Assisted Reproduction and Genetics, 40, pp. 1265 - 1280, http://dx.doi.org/10.1007/s10815-023-02796-x

Shamsa A; Gilchrist RB; Robertson DM; Rodgers RJ; Donoghoe MW; Ledger WL; Abbott JA; Riepsamen AH, 2023, 'Oocyte-Secreted Serum Biomarkers GDF9 and BMP15 in Women with Endometriosis', Reproductive Sciences, 30, pp. 1521 - 1527, http://dx.doi.org/10.1007/s43032-022-01107-6

McCredie S; An B; McShane M; Ledger W; Venetis CA, 2023, 'Serum anti-Müllerian hormone (AMH) concentration during pregnancy: a longitudinal study', Reproduction and Fertility, 4, http://dx.doi.org/10.1530/RAF-22-0128

Riepsamen AH; Donoghoe MW; Indran IR; Hechtman L; Robertson DM; Gilchrist RB; Ledger WL; Yong EL, 2023, 'Serum GDF9 and BMP15 as potential markers of ovarian function in women with and without polycystic ovary syndrome', Clinical Endocrinology, 98, pp. 567 - 577, http://dx.doi.org/10.1111/cen.14851

Aflatounian A; Paris VR; Richani D; Edwards MC; Cochran BJ; Ledger WL; Gilchrist RB; Bertoldo MJ; Wu LE; Walters KA, 2022, 'Declining muscle NAD+ in a hyperandrogenism PCOS mouse model: Possible role in metabolic dysregulation', Molecular Metabolism, 65, http://dx.doi.org/10.1016/j.molmet.2022.101583

Xiong T; Paris VR; Edwards MC; Hu Y; Cochran BJ; Rye KA; Ledger WL; Padmanabhan V; Handelsman DJ; Gilchrist RB; Walters KA, 2022, 'Androgen signaling in adipose tissue, but less likely skeletal muscle, mediates development of metabolic traits in a PCOS mouse model', American Journal of Physiology - Endocrinology and Metabolism, 323, pp. E145 - E158, http://dx.doi.org/10.1152/ajpendo.00418.2021

Habibalahi A; Campbell JM; Bertoldo MJ; Mahbub SB; Goss DM; Ledger WL; Gilchrist RB; Wu LE; Goldys EM, 2022, 'Unique Deep Radiomic Signature Shows NMN Treatment Reverses Morphology of Oocytes from Aged Mice', Biomedicines, 10, http://dx.doi.org/10.3390/biomedicines10071544

Choi SKY; Venetis C; Ledger W; Havard A; Harris K; Norman RJ; Jorm LR; Chambers GM, 2022, 'Population-wide contribution of medically assisted reproductive technologies to overall births in Australia: Temporal trends and parental characteristics', Human Reproduction, 37, pp. 1047 - 1058, http://dx.doi.org/10.1093/humrep/deac032

Campbell JM; Mahbub SB; Bertoldo MJ; Habibalahi A; Goss DM; Ledger WL; Gilchrist RB; Wu LE; Goldys EM, 2022, 'Multispectral autofluorescence characteristics of reproductive aging in old and young mouse oocytes', Biogerontology, 23, pp. 237 - 249, http://dx.doi.org/10.1007/s10522-022-09957-y

Li HWR; Nelson SMG; Ledger WL, 2022, 'Editorial: Clinical Applications of Anti-Mullerian Hormone and Its Measurement in Reproductive Medicine and Women’s Health', Frontiers in Endocrinology, 13, http://dx.doi.org/10.3389/fendo.2022.879053

Crespi S; Hu XH; Johnson B; Griesinger G; Ledger WL; Heisel O; Kolibianakis EM, 2022, 'Patient burden and healthcare resource utilization of regimens for ovarian stimulation', Reproductive Biomedicine Online, 44, pp. 573 - 581, http://dx.doi.org/10.1016/j.rbmo.2021.03.019

Nesbitt-Hawes EM; Dietz HP; Ledger WL; Abbott JA, 2022, 'Four-dimensional ultrasound biometry following botulinum toxin type A injection to the pelvic floor', Neurourology and Urodynamics, 41, pp. 375 - 382, http://dx.doi.org/10.1002/nau.24833

XIONG T; PARIS VRODRIGUEZ; EDWARDS MC; COCHRAN BJ; RYE K-A; LEDGER WL; PADMANABHAN V; HANDELSMAN DJ; GILCHRIST RB; WALTERS KA, 2022, 'Androgen Actions in Adipose Tissue, But Not Skeletal Muscle, are Involved in the Development of Metabolic PCOS Features in a Mouse Model', Fertility & Reproduction, 04, pp. 169 - 169, http://dx.doi.org/10.1142/s2661318222740814

GILCHRIST RB; RICHANI D; CULLINAN R; DALATI S; TILIA L; ANAZODO A; LEDGER WL; RODGERS RJ, 2022, 'Application of Ex-Vivo In Vitro Maturation (IVM) to Fertility Preservation in Cancer Patients', Fertility & Reproduction, 04, pp. 133 - 133, http://dx.doi.org/10.1142/s2661318222740450

HABIBALAHI A; BERTOLDO MJ; MAHBUB SB; CAMPBELL JM; GOSS DM; LEDGER WL; GILCHRIST RB; WU LE; GOLDYS EM, 2022, 'Assessment of Oocyte Quality Using Deep Radiomic Signature of Oocyte Morphology in the Mouse', Fertility & Reproduction, 04, pp. 135 - 135, http://dx.doi.org/10.1142/s2661318222740474

BIGGS S; LEWIS S; KENNEDY J; CHAMBERS G; MCLACHLAN R; O’BRYAN M; von SALDERN S; HART R; KHASHABA S; LEDGER W; NICOL C; ROMBAUTS L; STERN K; YAZDANI A; HALLIDAY J, 2022, 'Opportunities and Challenges Arising from the Australian Male Infertility Exposure (AMIE) Study', Fertility & Reproduction, 04, pp. 174 - 174, http://dx.doi.org/10.1142/s2661318222740851

HABIBALAHI A; CULLINAN R; TILLIA L; DALATI S; MAHBUB SB; CAMPBELL JM; RIEPSAMEN A; GILCHRIST RB; LEDGER WL; GOLDYS EM, 2022, 'Prediction of Progression from Oocyte to Useable Blastocyst Using Deep Radiomic Signatures: Preliminary Results', Fertility & Reproduction, 04, pp. 136 - 136, http://dx.doi.org/10.1142/s2661318222740486

RIEPSAMEN AH; DONOGHOE MW; INDRAN IR; LIEN S; HECHTMAN L; ROBERTSON DM; GILCHRIST RB; YONG E-L; LEDGER WL, 2022, 'Serum GDF9 and BMP15 as Markers of Ovarian Function in Healthy Women and Women with Polycystic Ovary Syndrome', Fertility & Reproduction, 04, pp. 141 - 141, http://dx.doi.org/10.1142/s266131822274053x

Ko JKY; Kan A; Leung P; Lee VCY; Li RHW; Ledger W; Ng EHY, 2021, 'Comparison of the number of oocytes obtained after ovarian stimulation between Chinese and Caucasian women undergoing in vitro fertilization using a standardized stimulation regime', Journal of Ovarian Research, 14, http://dx.doi.org/10.1186/s13048-021-00928-4

Rodgers RJ; Abbott JA; Walters KA; Ledger WL, 2021, 'Translational Physiology of Anti-Müllerian Hormone: Clinical Applications in Female Fertility Preservation and Cancer Treatment', Frontiers in Endocrinology, 12, pp. 689532, http://dx.doi.org/10.3389/fendo.2021.689532

Riepsamen AH; Donoghoe MW; Baerwald A; Pankhurst MW; Lien S; Chong YH; Robertson DM; Ledger WL; Gilchrist RB, 2021, 'Exploratory analysis of serum concentrations of oocyte biomarkers growth differentiation factor 9 and bone morphogenetic protein 15 in ovulatory women across the menstrual cycle', Fertility and Sterility, 116, pp. 546 - 557, http://dx.doi.org/10.1016/j.fertnstert.2021.02.001

Paris VR; Edwards MC; Aflatounian A; Bertoldo MJ; Ledger WL; Handelsman DJ; Gilchrist RB; Walters KA, 2021, 'Pathogenesis of reproductive and metabolic PCOSTraits in a mouse model', Journal of the Endocrine Society, 5, http://dx.doi.org/10.1210/jendso/bvab060

Li HWR; Robertson DM; Burns C; Ledger WL, 2021, 'Challenges in Measuring AMH in the Clinical Setting', Frontiers in Endocrinology, 12, http://dx.doi.org/10.3389/fendo.2021.691432

Riepsamen AH; Donoghoe MW; Baerwald A; Pankhurst MW; Lien S; Chong YH; Robertson DM; Ledger WL; Gilchrist RB, 2021, 'Serum Concentrations of GDF9 and BMP15 Across the Menstrual Cycle', Journal of the Endocrine Society, 5, pp. A734 - A735, http://dx.doi.org/10.1210/jendso/bvab048.1494

Chambers GM; Choi SKY; Irvine K; Venetis C; Harris K; Havard A; Norman RJ; Lui K; Ledger W; Jorm LR, 2021, 'A bespoke data linkage of an IVF clinical quality registry to population health datasets; methods and performance', International Journal of Population Data Science, 6, pp. 1679, http://dx.doi.org/10.23889/ijpds.v6i1.1679

Shyamsunder A; Hardy T; Yazdani A; Polyakov A; Norman R; Hart R; Agresta F; Rombauts L; Boothroyd C; Chapman M; Sweeten P; Somerville E; Jose R; Wand H; Ledger WL, 2021, 'Higher Doses of FSH Used for Superovulation Do Not Adversely Affect Embryonic Ploidy: A Randomized Controlled Trial (STimulation Resulting in Embryonic Aneuploidy using Menopur (STREAM) Trial)', Fertility & Reproduction, 03, pp. 108 - 114, http://dx.doi.org/10.1142/s2661318221500146

Rodriguez Paris V; Solon-Biet SM; Senior AM; Edwards MC; Desai R; Tedla N; Cox MJ; Ledger WL; Gilchrist RB; Simpson SJ; Handelsman DJ; Walters KA, 2020, 'Defining the impact of dietary macronutrient balance on PCOS traits', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-19003-5

Ombelet W; van Eekelen R; McNally A; Ledger W; Doody K; Farquhar C, 2020, 'Should couples with unexplained infertility have three to six cycles of intrauterine insemination with ovarian stimulation or in vitro fertilization as first-line treatment?', Fertility and Sterility, 114, pp. 1141 - 1148, http://dx.doi.org/10.1016/j.fertnstert.2020.10.029

Chambers GM; Keller E; Choi S; Khalaf Y; Crawford S; Botha W; Ledger W, 2020, 'Funding and public reporting strategies for reducing multiple pregnancy from fertility treatments', Fertility and Sterility, 114, pp. 715 - 721, http://dx.doi.org/10.1016/j.fertnstert.2020.08.1405

Makeyeva Y; Nicol C; Ledger WL; Ryugo DK, 2020, 'Immunocytochemical Localization of Olfactory-signaling Molecules in Human and Rat Spermatozoa', Journal of Histochemistry and Cytochemistry, 68, pp. 491 - 513, http://dx.doi.org/10.1369/0022155420939833

Aflatounian A; Edwards MC; Paris VR; Bertoldo MJ; Desai R; Gilchrist RB; Ledger WL; Handelsman DJ; Walters KA, 2020, 'Androgen signaling pathways driving reproductive and metabolic phenotypes in a PCOS mouse model', Journal of Endocrinology, 245, pp. 381 - 395, http://dx.doi.org/10.1530/JOE-19-0530

Paris VR; Kaakoush NO; Solon-Biet SM; Edwards MC; Ledger WL; Gilchrist RB; Simpson SJ; Handelsman DJ; Walters KA, 2020, 'MON-022 Dissecting the Interplay Between Diet and PCOS Pathology on Gut Microbiota in a PCOS Mouse Model', Journal of the Endocrine Society, 4, http://dx.doi.org/10.1210/jendso/bvaa046.568

Cox MJ; Edwards MC; Aflatounian A; Paris VR; Ledger WL; Gilchrist RB; Handelsman DJ; Walters KA, 2020, 'SAT-018 Androgen Actions in Adipose Tissue and the Brain Are Key Mediators in the Development of Polycystic Ovary Syndrome', Journal of the Endocrine Society, 4, http://dx.doi.org/10.1210/jendso/bvaa046.088

Alshehre SM; Duffy S; Jones G; Ledger WL; Metwally M, 2020, 'A prospective, single-centre, single-arm, open label study of the long term use of a gonadotropin releasing hormone agonist (Triptorelin SR, 11.25 mg) in combination with Tibolone add-back therapy in the management of chronic cyclical pelvic pain', Reproductive Biology and Endocrinology, 18, http://dx.doi.org/10.1186/s12958-020-00586-z

Wang Y; Logan S; Stern K; Wakefield CE; Cohn RJ; Agresta F; Jayasinghe Y; Deans R; Segelov E; McLachlan RI; Gerstl B; Sullivan E; Ledger WE; Anazodo A, 2020, 'Supportive oncofertility care, psychological health and reproductive concerns: a qualitative study', Supportive Care in Cancer, 28, pp. 809 - 817, http://dx.doi.org/10.1007/s00520-019-04883-1

Raymer J; Guan Q; Norman RJ; Ledger W; Chambers GM, 2020, 'Projecting future utilization of medically assisted fertility treatments', Population Studies, 74, pp. 23 - 38, http://dx.doi.org/10.1080/00324728.2019.1676461

Cox MJ; Edwards MC; Paris VR; Aflatounian A; Ledger WL; Gilchrist RB; Padmanabhan V; Handelsman DJ; Walters KA, 2020, 'Androgen Action in Adipose Tissue and the Brain are Key Mediators in the Development of PCOS Traits in a Mouse Model', Endocrinology (United States), 161, pp. 1 - 15, http://dx.doi.org/10.1210/ENDOCR/BQAA061

Rozen G; Rogers P; Chander S; Anderson R; McNally O; Umstad M; Winship A; Hutt K; Teh WT; Dobrotwir A; Hart R; Ledger W; Stern K, 2020, 'Clinical summary guide: Reproduction in women with previous abdominopelvic radiotherapy or total body irradiation', Human Reproduction Open, 2020, http://dx.doi.org/10.1093/hropen/hoaa045

Ataman LM; Rodrigues JK; Marinho RM; Caetano JPJ; Chehin MB; Alves da Motta EL; Serafini P; Suzuki N; Furui T; Takae S; Sugishita Y; Morishige KI; Almeida-Santos T; Melo C; Buzaglo K; Irwin K; Hamish Wallace W; Anderson RA; Mitchell RT; Telfer EE; Adiga SK; Anazodo A; Stern C; Sullivan E; Jayasinghe Y; Orme L; Cohn R; McLachlan R; Deans R; Agresta F; Gerstl B; Ledger WL; Robker RL; de Meneses e Silva JM; Melo e Silva LHF; Lunardi FO; Lee JR; Suh CS; de Vos M; van Moer E; Stoop D; Vloeberghs V; Smitz J; Tournaye H; Wildt L; Winkler-Crepaz K; Andersen CY; Smith BM; Smith K; Woodruff TK, 2020, 'Creating a global community of practice for oncofertility', Journal of Global Oncology, 6, pp. 317 - 330, http://dx.doi.org/10.1200/JGO.2015.000307

Ataman LM; Rodrigues JK; Marinho RM; Caetano JPJ; Chehin MB; Alves da Motta EL; Serafini P; Suzuki N; Furui T; Takae S; Sugishita Y; Morishige K-I; Almeida-Santos T; Melo C; Buzaglo K; Irwin K; Wallace WH; Anderson RA; Mitchell RT; Telfer EE; Adiga SK; Anazodo A; Stern C; Sullivan E; Jayasinghe Y; Orme L; Cohn R; McLachlan R; Deans R; Agresta F; Gerstl B; Ledger WL; Robker RL; de Meneses E Silva JM; Melo E Silva LHF; Lunardi FO; Lee JR; Suh CS; De Vos M; Van Moer E; Stoop D; Vloeberghs V; Smitz J; Tournaye H; Wildt L; Winkler-Crepaz K; Andersen CY; Smith BM; Smith K; Woodruff TK, 2020, 'Creating a Global Community of Practice for Oncofertility.', JCO Glob Oncol, 6, pp. 317 - 330, http://dx.doi.org/10.1200/GO.22.00007

Ledger W, 2019, 'Preimplantation genetic screening should be used in all in vitro fertilisation cycles in women over the age of 35 years: AGAINST: Pre-implantation genetic screening should not be used in all IVF cycles in women over the age of 35 years', BJOG an International Journal of Obstetrics and Gynaecology, 126, pp. 1555, http://dx.doi.org/10.1111/1471-0528.15942

Anazodo A; Laws P; Logan S; Saunders C; Travaglia J; Gerstl B; Bradford N; Cohn R; Birdsall M; Barr R; Suzuki N; Takae S; Marinho R; Xiao S; Chen QH; Mahajan N; Patil M; Gunasheela D; Smith K; Sender L; Melo C; Almeida-Santos T; Salama M; Appiah L; Su I; Lane S; Woodruff TK; Pacey A; Anderson RA; Shenfield F; Sullivan E; Ledger W, 2019, 'The Development of an International Oncofertility Competency Framework: A Model to Increase Oncofertility Implementation', Oncologist, 24, pp. e1450 - e1459, http://dx.doi.org/10.1634/theoncologist.2019-0043

Chambers GM; Harrison C; Raymer J; Raymer AKP; Britt H; Chapman M; Ledger W; Norman RJ, 2019, 'Infertility management in women and men attending primary care - Patient characteristics, management actions and referrals', Human Reproduction, 34, pp. 2173 - 2183, http://dx.doi.org/10.1093/humrep/dez172

Costello M; Garad R; Hart R; Homer H; Johnson L; Jordan C; Mocanu E; Qiao J; Rombauts L; Teede HJ; Vanky E; Venetis C; Ledger W, 2019, 'A Review of First Line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome', Medical Sciences Basel Switzerland, 7, http://dx.doi.org/10.3390/medsci7090095

Fraison E; Crawford G; Casper G; Harris V; Ledger W, 2019, 'Pregnancy following diagnosis of premature ovarian insufficiency: a systematic review', Reproductive Biomedicine Online, 39, pp. 467 - 476, http://dx.doi.org/10.1016/j.rbmo.2019.04.019

Riepsamen AH; Chan K; Lien S; Sweeten P; Donoghoe MW; Walker G; Fraison EHJ; Stocker WA; Walton KL; Harrison CA; Ledger WL; Robertson DM; Gilchrist RB, 2019, 'Serum Concentrations of Oocyte-Secreted Factors BMP15 and GDF9 during IVF and in Women with Reproductive Pathologies', Endocrinology, 160, pp. 2298 - 2313, http://dx.doi.org/10.1210/en.2019-00264

Back to profile page