By Professor Christopher John Ormandy

Journal articles

Linderman GJ; Wittlin S; Naylor MJ; Santamaria M; Zhang J; Starr R; Hilton D; Alexander WS; Ormandy CJ; Visvader J, 2001, 'SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor deficient mice.', Genes and Development, 15, pp. 1631 - 1639

Binart N; Ormandy CJ; Kelly PA, 2000, 'Mammary gland development and the prolactin receptor', Advances in Experimental Medicine and Biology, 480, pp. 85 - 92

Binart N; Helloco C; Ormandy CJ; Barra J; Cle Ment-Lacroix P; Baran N; Kelly PA, 2000, 'Rescue of Preimplantatory Egg Development and Embryo Implantation in Prolactin Receptor-Deficient Mice after Progesterone Administration.', Endocrinology, 141, pp. 2691 - 2697, http://dx.doi.org/10.1210/endo.141.7.7568

Binart N; Helloco C; Ormandy CJ; Barra J; Clément-Lacroix P; Baran N; Kelly PA, 2000, 'Rescue of preimplantatory egg development and embryo implantation in prolactin receptor-deficient mice after progesterone administration.', Endocrinology, 141, pp. 2691 - 2697, http://dx.doi.org/10.1210/endo.141.7.7568

Goffin V; Binart N; Clément-Lacroix P; Bouchard B; Bole-Feysot C; Edery M; Lucas BK; Touraine P; Pezet A; Maaskant R; Pichard C; Helloco C; Baran N; Favre H; Bernichtein S; Allamando A; Ormandy C; Kelly PA, 1999, 'From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models', Genetic Analysis Biomolecular Engineering, 15, pp. 189 - 201, http://dx.doi.org/10.1016/S1050-3862(99)00025-X

Bouchard B; Ormandy CJ; Di Santo JP; Kelly PA, 1999, 'Immune system development and function in prolactin receptor-deficient mice', Journal of Immunology, 163, pp. 576 - 582, http://dx.doi.org/10.4049/jimmunol.163.2.576

Cle Ment-Lacroix P; Ormandy C; Lepescheux LN; Ammann P; Damotte D; Goffin V; Bouchard B; Amling M; Gaillard-Kelly M; Binart N; Baron R; Kelly PA, 1999, 'Osteoblasts Are a New Target for Prolactin: Analysis of Bone Formation in Prolactin Receptor Knockout Mice* *This work was supported in part by grants from Hoechst Marion Roussel, Inc.', Endocrinology, 140, pp. 96 - 105, http://dx.doi.org/10.1210/endo.140.1.6436

Clement-Lacroix P; Ormandy C; Lepescheux L; Ammann P; Damotte D; Goffin V; Bouchard B; Amling M; Gaillard-Kelly M; Binart N; Baron R; Kelly PA, 1999, 'Osteoblasts Are a New Target for Prolactin', Obstetrical & Gynecological Survey, 54, pp. 383 - 384, http://dx.doi.org/10.1097/00006254-199906000-00018

Clément-Lacroix P; Ormandy C; Lepescheux L; Ammann P; Damotte D; Goffin V; Bouchard B; Amling M; Gaillard-Kelly M; Binart N; Baron R; Kelly PA, 1999, 'Osteoblasts are a new target for prolactin: analysis of bone formation in prolactin receptor knockout mice.', Endocrinology, 140, pp. 96 - 105, http://dx.doi.org/10.1210/endo.140.1.6436

Brisken C; Kaur S; Chavarria TE; Binart N; Sutherland RL; Weinberg RA; Kelly P; Ormandy CJ, 1999, 'Prolactin controls mammary gland development via direct and indirect mechanisms', Developmental Biology, pp. 96 - 106

Wynick D; Small CJ; Bacon A; Holmes FE; Norman M; Ormandy CJ; Kilic E; Kerr NCH; Ghatei M; Talamantes F; Bloom SR; Pachnis V, 1998, 'Galanin regulates prolactin release and lactotroph proliferation', Proceedings of the National Academy of Sciences of the United States of America, 95, pp. 12671 - 12676, http://dx.doi.org/10.1073/pnas.95.21.12671

Lucas BK; Ormandy CJ; Binart N; Bridges RS; Kelly PA, 1998, 'Null Mutation of the Prolactin Receptor Gene Produces a Defect in Maternal Behavior', Endocrinology, 139, pp. 4102 - 4107, http://dx.doi.org/10.1210/endo.139.10.6243

Goffin V; Bouchard B; Ormandy CJ; Weimann E; Ferrag F; Touraine P; Bole-Feysot C; Maaskant RA; Clement-Lacroix P; Edery M; Binart N; Kelly PA, 1998, 'Prolactin: A hormone at the crossroads of neuroimmunoendocrinology', Annals of the New York Academy of Sciences, 840, pp. 498 - 509, http://dx.doi.org/10.1111/j.1749-6632.1998.tb09588.x

Ormandy CJ; Binart N; Helloco C; Kelly PA, 1998, 'Mouse prolactin receptor gene: Genomic organization reveals alternative promoter usage and generation of isoforms via alternative 3'-exon splicing', DNA and Cell Biology, 17, pp. 761 - 770, http://dx.doi.org/10.1089/dna.1998.17.761

Lucas BK; Ormandy CJ; Binart N; Bridges RS; Kelly PA, 1998, 'Null mutation of the prolactin receptor gene produces a defect in maternal behavior', Endocrinology, 139, pp. 4102 - 4107, http://dx.doi.org/10.1210/endo.139.10.6243

Ormandy CJ; Lee CC; Ormandy HF; Fantl V; Shine J; Peters G; Sutherland RL, 1998, 'Amplification, expression and steroid regulation of the preprogalanin gene in human breast cancer', Cancer research, pp. 1353 - 1357

Ormandy CJ; Hui R; Sutherland RL, 1998, 'Galanin and 11q13 amplification in human breast cancer', Biotech Lab Int, pp. 14 - 16

Kelly PA; Ormandy CJ; Bôle-Feysot C; Maaskant R; Freemark M; Binart N, 1998, 'Prolactin receptors and embryonic development: Gene expression and knockout studies', Placenta, 19, pp. 13 - 21, http://dx.doi.org/10.1016/s0143-4004(98)80003-9

Bignon C; Binart N; Ormandy C; Schuler LA; Kelly PA; Djiane J, 1997, 'Long and short forms of the ovine prolactin receptor: cDNA cloning and genomic analysis reveal that the two forms arise by different alternative splicing mechanisms in ruminants and in rodents', Journal of Molecular Endocrinology, 19, pp. 109 - 120, http://dx.doi.org/10.1677/jme.0.0190109

Ormandy CJ; Camus A; Barra J; Damotte D; Lucas B; Buteau H; Edery M; Brousse N; Babinet C; Binart N; Kelly PA, 1997, 'Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse', Genes and Development, 11, pp. 167 - 178, http://dx.doi.org/10.1101/gad.11.2.167

Ormandy CJ; Binart N; Kelly PA, 1997, 'Mammary gland development in prolactin receptor knockout mice.', Journal of Mammary Gland Biology and Neoplasia, 2, pp. 355 - 364, http://dx.doi.org/10.1023/A:1026395229025

Ormandy CJ; Hall R; Manning DL; Robertson JF; Blamey RW; Kelly P; Nicholson RI; Sutherland RL, 1997, 'Coexpression and cross-regulation of the prolactin receptor and sex steroid hormone receptors in Breast cancer', Journal of Clinical Endocrinology and Metabolism, pp. 3692 - 3699

Binart N; Ormandy C; Kelly PA, 1997, 'Le récepteur de la prolactine : une molécule-clé de la reproduction ?', médecine/sciences, 13, pp. 734 - 734, http://dx.doi.org/10.4267/10608/451

Lee CSL; DeFazio A; Ormandy CJ; Sutherland RL, 1996, 'Inverse regulation of oestrogen receptor and epidermal growth factor receptor genbe expression in MCF-7 breast cancer cells treated with phorbol ester', Journal of Steroid Biochemistry and Molecular Biology, 58, pp. 267 - 275, http://dx.doi.org/10.1016/0960-0760(96)00039-8

Møldrup A; Ormandy C; Nagano M; Murthy K; Banville D; Tronche F; Kelly PA, 1996, 'Differential promoter usage in prolactin receptor gene expression: hepatocyte nuclear factor 4 binds to and activates the promoter preferentially active in the liver.', Mol Endocrinol, 10, pp. 661 - 671, http://dx.doi.org/10.1210/mend.10.6.8776726

Manning DL; McClelland RA; Knowlden JM; Bryant S; Gee JMW; Green CD; Robertson JF; Blamey RW; Sutherland RL; Ormandy CJ; Nicholson RI, 1995, 'Differential expression of oestrogen regulated genes in breast cancer', Acta Oncologica, 34, pp. 641 - 646, http://dx.doi.org/10.3109/02841869509094041

Kelly PA; Edery M; Finidori J; Postel-Vinay MC; Gougon L; Ali S; Dinerstein H; Sotiropoulos A; Lochnan H; Ferrag F; Lebrun JJ; Ormandy C; Buteau H; Esposito N; Vincent V; Möldrup A, 1994, 'Receptor Domains Involved in Signal Transduction of Prolactin and Growth Hormone', Proceedings of the Society for Experimental Biology and Medicine, 206, pp. 280 - 283, http://dx.doi.org/10.3181/00379727-206-43759

Ormandy CJ; Sutherland RL, 1993, 'At the cutting edge - Mechanisms of prolactin receptor regulation in mammary gland', Molecular and Cellular Endocrinology, 91, http://dx.doi.org/10.1016/0303-7207(93)90247-H

Roman SD; Clarke CL; Ormandy CJ, 1993, 'Estradiol Induction of Retinoic Acid Receptors in Human Breast Cancer Cells', Cancer Research, 53, pp. 5940 - 5945

Ormandy CJ; Sutherland RL, 1993, 'Mechanisms of prolactin receptor regulation in mammary gland', Molecular and Cellular Endocrinology, 91, pp. C1 - C6, http://dx.doi.org/10.1016/0303-7207(93)90247-H

Ormandy CJ; Lee CSL; Kelly PA; Sutherland RL, 1993, 'Regulation of prolactin receptor expression by the tumour promoting phorbol ester 12‐O‐tetradecanoylphorbol‐13‐acetate in human breast cancer cells', Journal of Cellular Biochemistry, 52, pp. 47 - 56, http://dx.doi.org/10.1002/jcb.240520108

Ormandy CJ; de Fazio A; Kelly PA; Sutherland RL, 1992, 'Coordinate regulation of oestrogen and prolactin receptor expression by sodium butyrate in human breast cancer cells', Biochemical and Biophysical Research Communications, 182, pp. 740 - 745, http://dx.doi.org/10.1016/0006-291X(92)91794-Q

Ormandy CJ; Clarke CL; Kelly PA; Sutherland RL, 1992, 'Androgen regulation of prolactin‐receptor gene expression in MCF‐7 and MDA‐MB‐453 human breast cancer cells', International Journal of Cancer, 50, pp. 777 - 782, http://dx.doi.org/10.1002/ijc.2910500519

Ormandy CJ; Graham J; Kelly PA; Clarke CL; Sutherland RL, 1992, 'The Effect of Progestins on Prolactin Receptor Gene Transcription in Human Breast Cancer Cells', DNA and Cell Biology, 11, pp. 721 - 726, http://dx.doi.org/10.1089/dna.1992.11.721

Ormandy CJ; De Fazio A; Kelly PA; Sutherland RL, 1992, 'Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells', Endocrinology, 131, pp. 982 - 984, http://dx.doi.org/10.1210/endo.131.2.1639037

Ormandy CJ; de Fazio A; Kelly PA; Sutherland RL, 1992, 'Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells.', Endocrinology, 131, pp. 982 - 984, http://dx.doi.org/10.1210/endo.131.2.1639037

Ormandy CJ; Clarke CL; Sutherland RL, 1990, 'Solubilization and characterization of a lactogenic receptor from human placental chorion membranes', Journal of Cellular Biochemistry, 43, pp. 1 - 15, http://dx.doi.org/10.1002/jcb.240430102

Teh TC; Ormandy CJ; Surus AS; Sutherland RL; Chapman GE, 1988, 'Human growth hormone binds to lactogenic receptors in bovine, ovine and rat adrenals', Hormone and Metabolic Research, 20, pp. 278 - 281, http://dx.doi.org/10.1055/s-2007-1010815

Conference Papers

Ortega DG; Ledger A; Roden D; Cho C; Allerdice S; Lee H; Valdes-Mora F; Salomon R; Oakes S; Ormandy C, 2014, 'THE ETS TRANSCRIPTION FACTOR ELF5 IS A KEY DETERMINANT OF THE LETHAL PHENOTYPE IN LUMINAL BREAST CANCER, DRIVING THE ACQUISITION OF ANTIESTROGEN RESISTANCE AND METASTATIC ACTIVITY', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 16 - 17, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

O'Toole S; Swarbrick A; Millar E; McLeod D; McNeil C; Qiu M; Lopez-Knowles E; Caldon E; Oakes S; Ormandy C; Morey A; Musgrove E; Henshall S; Sutherland R, 2009, 'Aberrent hedgehog signaling is an early event in breast cancer development.', in Cancer Research, American Association for Cancer Research (AACR), pp. 24 - 24, http://dx.doi.org/10.1158/0008-5472.sabcs-24

O Toole SJ; Swarbrick A; Millar E; McLeod D; Mcneil CM; Qiu MR; Lopez-Knowles E; Caldon E; Oakes SR; Ormandy CJ; Morey AL; Musgrove EA; Henshall SM; Sutherland RL, 2009, 'Aberrent hedgehog signaling is an early event in breast cancer development', in Cancer research, American Association Cancer Research, Philadelphia, PA, pp. 70S - 70S

Bhandari M; Kawamoto M; Thomas A; Carati C; Ormandy CJ; Toouli J; Saccone GT, 2007, 'Galanin knockout mice are less susceptible to caerulein-induced acute pancreatitis', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A250 - A250, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000245927602142&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Williams E; Chaffer C; Oakes SR; Ormandy CJ; Blick T; Thompson E, 2007, 'Mesenchymal to epithetial transition in the establishment of secondary tumours: insights from a bladder carcinoma progression series', in Clinical and Experimental Metastasis, Kluwer Academic Publ, pp. 262 - 262

Williams ED; Chaffer CL; Oakes SR; Ormandy CJ; Blick T; Thompson EW, 2006, 'Mesenchymal to epithelial transition in the establishment of secondary tumors: Insights from a bladder carcinoma progression series', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606204397&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

ClementLacroix P; Ormandy CJ; Lepescheux L; Goffin V; Bouhard B; Amling M; Binart N; GaillardKelly M; Baron R; Kelly PA, 1997, 'Analysis of bone from prolactin receptor knockout mice: Influence of prolactin in normal murine osteoblasts.', in JOURNAL OF BONE AND MINERAL RESEARCH, BLACKWELL SCIENCE INC, pp. 156 - 156, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XP62700156&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts

Gallego-Ortega D; Ledger A; Roden D; Cho C; Allerdice SL; Lee HJ; Valdes-Mora F; Lee B; Kaplan W; Salomon R; Piggin C; Rabinovich B; Millar E; Chtanova T; Swarbrick A; Clark S; Ormandy C, 2015, 'The ETS transcription factor ELF5 drives metastasis via angiogenesis and recruitment of Gr-1+ CD11b+ myeloid derived suppressor cells in luminal breast cancer', in Clinical and Experimental Metastasis, Springer Verlag (Germany), Vol. 32, pp. 203 - 203, presented at MRS 15th International biennial congress of the metastasis research society

Nair R; Teo WS; Ye S; McFarland A; Harvey K; Roden D; Junankar S; Baker L; Yang J; Fluke N; Millar E; Mellick A; Naylor M; Ormandy C; Lakhani S; O'Toole S; Swarbrick A, 2015, 'The Inhibitor of Differentiation proteins mediate tumour-initiating properties and metastasis in breast cancer', in CLINICAL & EXPERIMENTAL METASTASIS, SPRINGER, Vol. 32, pp. 224 - 224, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351601900129&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Byrne FL; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2012, 'Stathmin suppression influences ROCK signaling and reduces cell invasion and metastasis in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1444

Reports

Ormandy CJ, 2004, Discovery of Novel Mammary Developmental and Cancer Genes Using ENU Mutagenesis, Defense Technical Information Center, http://dx.doi.org/10.21236/ada431370, https://doi.org/10.21236/ada431370

Preprints

Saunus JM; De Luca XM; Northwood K; Raghavendra A; Hasson A; McCart Reed AE; Lim M; Lal S; Vargas AC; Kutasovic JR; Dalley AJ; Miranda M; Kalaw E; Kalita-de Croft P; Gresshoff I; Al-Ejeh F; Gee JMW; Ormandy C; Khanna KK; Beesley J; Chenevix-Trench G; Green AR; Rakha EA; Ellis IO; Nicolau DV; Simpson PT; Lakhani SR, 2021, Epigenome erosion drives neural crest-like phenotypic mimicry in triple-negative breast cancer and other SOX10+ malignancies, http://dx.doi.org/10.1101/2021.03.30.437624

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