By Dr John Walter Frew

Book Chapters

Grand D; Frew JW; Hawkes JE, 2023, '17 Epigenetics', in Atopic Dermatitis : Inside Out Or Outside in, Elsevier, pp. 168 - 178, http://dx.doi.org/10.1016/b978-0-323-84744-5.00017-6

Pham JP; Frew JW, 2023, 'Management of Immunosuppressed Dermatology Patients During COVID-19', in Updates in Clinical Dermatology, Springer Nature Switzerland, pp. 109 - 120, http://dx.doi.org/10.1007/978-3-031-45586-5_11

Grand D; Frew JW; Hawkes JE, 2022, 'Epigenetics', in Atopic Dermatitis Inside Out or Outside in, pp. 168 - 178, http://dx.doi.org/10.1016/B978-0-323-84744-5.00017-6

Frew JW, 2022, 'Follicular Occlusion and Inflammation', in A Comprehensive Guide to Hidradenitis Suppurativa, pp. 89 - 99, http://dx.doi.org/10.1016/B978-0-323-77724-7.00010-3

Lasschuit JWJ; Snaith JR; Frew JW, 2021, 'The skin and diabetes', in Skin and the Heart, pp. 283 - 298, http://dx.doi.org/10.1007/978-3-030-54779-0_18

Lasschuit JWJ; Snaith JR; Frew JW, 2021, 'The skin and diabetes', in Skin and the Heart, pp. C1, http://dx.doi.org/10.1007/978-3-030-54779-0_29

Lasschuit JWJ; Snaith JR; Frew JW, 2021, 'Correction to: The Skin and Diabetes', in Skin and the Heart, Springer International Publishing, pp. C1 - C1, http://dx.doi.org/10.1007/978-3-030-54779-0_29

Frew JW; Navrazhina K; Krueger JG, 2020, 'Hidradenitis Suppurativa (HS) and other disorders of ‘follicular occlusion’', in Stiehm S Immune Deficiencies Inborn Errors of Immunity, pp. 773 - 786, http://dx.doi.org/10.1016/B978-0-12-816768-7.00033-8

Grand D; Navrazhina K; Frew JW; Hawkes JE, 2020, 'Research Pipeline I: Oral Therapeutics for Psoriasis', in Advances in Psoriasis A Multisystemic Guide Second Edition, pp. 291 - 302, http://dx.doi.org/10.1007/978-3-030-54859-9_23

Frew JW; Murrell DF, 2015, 'Autoimmune Blistering Diseases and Corticosteroid Use: A Review of the Evidence', in Blistering Diseases: Clinical Features, Pathogenesis, Treatment, Springer Link, pp. 459 - 468, http://dx.doi.org/10.1007/978-3-662-45698-9_46

Frew JW; Chams Davatchi C; Murrell DF, 2015, 'Cyclophosphamide in Autoimmune Blistering Diseases: Safety, Efficacy and Evidence Base', in Blistering Diseases: Clinical Features, Pathogenesis, Treatment, Springer Link, pp. 507 - 513, http://dx.doi.org/10.1007/978-3-662-45698-9_51

Murrell DF; Frew JW, 2015, 'Living with Epidermolysis Bullosa: Reviewing the Impact on Individuals' Quality of Life', in Blistering Diseases: Clinical Features, Pathogenesis, Treatment, Springer Link, pp. 711 - 717, http://dx.doi.org/10.1007/978-3-662-45698-9_74

Journal articles

Ingram JR; Fujita H; Gottlieb AB; Lev-Tov H; Prens E; Sayed CJ; Shi VY; Szepietowski JC; Takahashi K; Frew JW; Lambert J; Davis L; Oh T; Rolleri R; Saintmard M-H; Orenstein LAV, 2025, 'Bimekizumab Pain Outcomes in Patients with Hidradenitis Suppurativa: Pooled 48-Week Results from BE HEARD I&II Phase 3 Randomized Clinical Trials', PAIN AND THERAPY, http://dx.doi.org/10.1007/s40122-025-00779-7

Aghajani M; Frew JW, 2025, 'New Findings in Hidradenitis Suppurativa Pathophysiology: Focus on B Cells, BAFF, BTK, and SYK', CURRENT DERMATOLOGY REPORTS, 14, http://dx.doi.org/10.1007/s13671-025-00487-7

Byrd AS; Moreau JM; Petukhova L; Frew J, 2025, 'Differentiating the Role of Inflammation in Hidradenitis Suppurativa from that in other Inflammatory Skin Diseases', Journal of Investigative Dermatology, 145, pp. 2417 - 2427, http://dx.doi.org/10.1016/j.jid.2025.04.009

Aghajani M; Maye E; Burrell K; Kok C; Frew JW, 2025, 'Evaluating the quality and readability of online information about hidradenitis suppurativa: a systematic review', Clinical and Experimental Dermatology, 50, pp. 1937 - 1944, http://dx.doi.org/10.1093/ced/llaf236

Bouazzi D; Nielsen SM; Hagan PG; Botvid S; Hove LS; Prens EP; Christensen R; Jemec GBE; GHiSA Group ; Knecht-Gurwin K; Szepietowski JC; Anaba EL; Chehad AS; Zobiri S; Serradj A; Bhuiyan MSI; Noor T; Guillem P; Parvizi MM; Saki N; Alpsoy E; Vardar C; Kanni T; Giamarellos-Bourboulis EJ; Frew JW; Al Maharbi WHA; van Huijstee JC; Aarts P; Dewi ST; Febriana SA; Indrastuti N; Suryawati N; Pangastuti M; Adji A; Akhyar G; Nopriyati N; Hazlianda CP; Reyes-Baraona F; Matas C; Saeed H; Moodley A; Binamer Y; Kamil MAA; Jocic I; Mijuskovic Z; Mallawaarachchi K; Gangani C; Tusheva I; Boshkovski VB; Hu D; Geng S; Medianfar CE; Saunte DML; Chandran NS; van der Zee HH; Zouboulis CC; Benhadou F; Villumsen B; Alavi A; Ibekwe PU; Hamzavi IH; Ingram JR; Naik HB; Garg A; Boer J, 2025, 'Prevalence of Hidradenitis Suppurativa: A Meta-Analysis of Global Hidradenitis Suppurativa Atlas Studies.', JAMA Dermatol, 161, pp. 1022 - 1028, http://dx.doi.org/10.1001/jamadermatol.2025.2373

Sholji T; Islam R; Pham J; Burrell K; Kok C; Frew JW, 2025, 'Quantifying time to medical and/or surgical therapy after diagnosis of hidradenitis suppurativa and pilonidal sinus disease: A propensity-matched real-world cohort analysis', Journal of the European Academy of Dermatology and Venereology, 39, pp. e671 - e672, http://dx.doi.org/10.1111/jdv.20494

Westerkam LL; Santiago-Soltero K; Charrow A; Frew JW; Sayed CJ, 2025, 'Safety and efficacy of biologics in patients with Down syndrome and hidradenitis suppurativa: A retrospective cohort study', Clinical and Experimental Dermatology, 50, pp. 1431 - 1433, http://dx.doi.org/10.1093/ced/llaf090

Sholji T; Islam R; Pham J; Kok C; Frew JW, 2025, 'Malignancy risk differs between hidradenitis suppurativa and pilonidal sinus disease', Journal of the American Academy of Dermatology, 92, pp. 1381 - 1382, http://dx.doi.org/10.1016/j.jaad.2025.01.076

Flora A; Pham J; Woods JA; Radzeika M; Dickson H; Malone M; Frew JW, 2025, 'The Clinical and Molecular Response of Pyoderma Gangrenosum to IL-23 Blockade: Result from a Proof-of-Concept Open-Label Clinical Trial', Journal of Investigative Dermatology, 145, pp. 1396 - 1406.e6, http://dx.doi.org/10.1016/j.jid.2024.10.602

Johns M; Kunst H; Tng V; Frew J; Kok C; Lee S; Bonilla GM, 2025, 'Comparison of Keratinocyte Cancer Tumour and Defect Sizes Treated by Mohs Micrographic Surgery: Sydney Versus Outside Metropolitan Sydney', Australasian Journal of Dermatology, 66, pp. e148 - e154, http://dx.doi.org/10.1111/ajd.14453

Stewart TJ; Chan CWJ; Shah H; Frew J, 2025, 'Infectious complications of Stevens-Johnson syndrome and toxic epidermal necrolysis: A systematic review and meta-analysis', International Journal of Dermatology, 64, pp. 830 - 848, http://dx.doi.org/10.1111/ijd.17527

Stewart TJ; Shah H; Frew J, 2025, 'Systematic review and meta-analysis of non-SCORTEN predictors of mortality in Stevens-Johnson syndrome and toxic epidermal necrolysis', International Journal of Dermatology, 64, pp. 849 - 860, http://dx.doi.org/10.1111/ijd.17529

Hashemi-Arend A; Lowes MA; Frew JW; Krueger J; Gierbolini A; Nayim M; Samanoglu M; Mbye PM; Shahriar F; Tobin JN; Kost RG, 2025, 'Full spectrum town halls for hidradenitis suppurativa: A model for advancing clinician-patient-researcher engagement in clinical and translational research', Journal of Clinical and Translational Science, 9, http://dx.doi.org/10.1017/cts.2025.62

Pham J; Frew JW, 2025, 'Hidradenitis Suppurativa: Pathogenesis and Inflammatory Pathways', Dermatologic Clinics, 43, pp. 179 - 191, http://dx.doi.org/10.1016/j.det.2024.12.004

Frew J; Smith A; Penas PF; Ellis E; Foley P; Rubel D; McMeniman E; Marshman G; Saunders H; Veysey E; Nicolopolous J; Spelman L; Gebauer K, 2025, 'Australasian hidradenitis suppurativa management guidelines', Australasian Journal of Dermatology, 66, pp. 75 - 89, http://dx.doi.org/10.1111/ajd.14388

Frew JW, 2025, 'Unravelling the complex pathogenesis of hidradenitis suppurativa', British Journal of Dermatology, 192, pp. i3 - i14, http://dx.doi.org/10.1093/bjd/ljae238

Pham J; Flora A; Kozera EK; Medianfar CE; Bouazzi D; Christensen R; Jemec GBE; Frew JW, 2025, 'Diagnostic Accuracy of a Questionnaire Screening Test in Assessing the Prevalence of Hidradenitis Suppurativa in Sydney, Australia', Dermatology, http://dx.doi.org/10.1159/000540455

Greenlund L; Herzog C; Wendland Z; Rypka K; Frew JW; Kirby JS; Alavi A; Khalid B; Lowes MA; Garg A; Marzano AV; Zouboulis CC; Tzellos T; Jaleel T; Goldfarb N, 2025, 'Discrepancies in hidradenitis suppurativa lesion characterization by providers and patients', Journal of the European Academy of Dermatology and Venereology, 39, pp. 210 - 220, http://dx.doi.org/10.1111/jdv.19999

Lam T; Gruzmark F; Ondreyka J; Lenczowski J; Harris-Tryon TA; Frew J; Lev-Tov H, 2025, 'Food as Medicine in Hidradenitis Suppurativa: A Review of Dietary Effects on Hidradenitis Suppurativa Pathogenesis', Integrative and Complementary Therapies, http://dx.doi.org/10.1177/27683192251376656

Wortsman X; Alfageme F; Dini V; García-Martínez FJ; Caposiena Caro RD; Frew J; Gonzalez C; Hamzavi IH; Kohli I; Krajewski PK; Kuyumllian M; Liu J; Mandava A; Nazzaro G; O'Brien E; Oranges T; Pelizzari M; Rezende J; Romani J; Sigrist R; Taleb E; Zattar L; Zavariz J; Martorell A, 2025, 'International consensus statement on the use of ultrasound in hidradenitis suppurativa', Journal of the European Academy of Dermatology and Venereology, http://dx.doi.org/10.1111/jdv.20600

Stewart TJ; Farrell JA; Cook D; Frew JW, 2025, 'Prevalence and predictors of posttraumatic stress disorder in Stevens Johnson syndrome and toxic epidermal necrolysis', Journal of the European Academy of Dermatology and Venereology, http://dx.doi.org/10.1111/jdv.20891

Pham J; Sholji T; Islam R; Burrell K; Kok C; Frew JW, 2025, 'Sequencing of Biologic Therapy in Hidradenitis Suppurativa: A Real-World Analysis of Treatment in Over 15,000 Patients', JEADV Clinical Practice, http://dx.doi.org/10.1002/jvc2.70083

Sampath AJ; Westerkam LL; Blum FR; Alhusayen R; Bechara FG; Caffrey J; Carmona-Rivera C; Chandran NS; George R; Goldberg SR; Gudjonsson JE; Hansen SL; Ingram JR; Kirby B; Marzano AV; Matusiak Ł; Orgill DP; Prens E; van der Zee HH; van Straalen KR; Zouboulis CC; Byrd AS; Frew JW; Lowes MA; Naik HB; Sokumbi O; Mi QS; Miedema JR; Googe PB; Sayed CJ, 2025, 'Standardized Protocols for Clinical and Histopathological Characterization of Hidradenitis Suppurativa Tissue Specimens', Journal of Investigative Dermatology, 145, pp. 50 - 55, http://dx.doi.org/10.1016/j.jid.2024.02.041

Aghajani M; Lu JT; Frew JW; Sebaratnam DF, 2025, 'The evolving genetic landscape of ILVEN: A comprehensive review', Journal of the European Academy of Dermatology and Venereology, http://dx.doi.org/10.1111/jdv.70098

Smith A; Frew J, 2025, 'Time to Recognise Psoriasis as a Cardiovascular Risk Modifier in National Guidance', Australasian Journal of Dermatology, http://dx.doi.org/10.1111/ajd.14587

Frew J; Flora A; Pham J; Woods J; Radzieta M; Dickson H; Malone M, 2025, '61257 The Clinical and Molecular Response of Pyoderma Gangrenosum to Interleukin 23 Blockade: Result from a proof-of-concept open-label clinical trial', Journal of the American Academy of Dermatology, 93, pp. AB313 - AB313, http://dx.doi.org/10.1016/j.jaad.2025.05.1236

Frew J; Pham J; Sholji T; Guttman L; Allen T, 2025, '61380 Predictors of wound healing after surgical deroofing in Hidradenitis Suppurativa', Journal of the American Academy of Dermatology, 93, pp. AB72 - AB72, http://dx.doi.org/10.1016/j.jaad.2025.05.292

Porter ML; Kirby B; Krueger JG; Bechara FG; Frew JW; Sayed CJ; Pinter A; Szepietowski JC; Bertolini M; Reich K; Kimball AB, 2025, '62297 Resolution of deep dermal inflammatory lesions with the Nanobody sonelokimab in moderate-to-severe hidradenitis suppurativa (HS): preclinical results and outcomes from the Phase 2 MIRA trial', Journal of the American Academy of Dermatology, 93, pp. AB290 - AB290, http://dx.doi.org/10.1016/j.jaad.2025.05.1146

Sayed CJ; Kirby B; Frew JW; Porter ML; Ingram JR; Prens E; Charrow AP; Gooderham MJ; Savage L; Reich K; Bechara FG, 2025, '62305 IHS4-100 responses and other IHS4 outcomes with the IL-17A- and IL-17F-inhibiting Nanobody sonelokimab in patients with moderate-to-severe hidradenitis suppurativa (HS): Week 24 results from the Phase 2 MIRA trial', Journal of the American Academy of Dermatology, 93, pp. AB221 - AB221, http://dx.doi.org/10.1016/j.jaad.2025.05.878

Tzellos T; Sayed CJ; Gottlieb AB; Becherel P-A; Kirby B; Asai J; Frew JW; Pansar I; Rolleri R; Tilt N; Porter ML, 2025, '64414 Bimekizumab impact on draining tunnel reduction over 2 years in moderate to severe hidradenitis suppurativa: Results from BE HEARD EXT', Journal of the American Academy of Dermatology, 93, pp. AB137 - AB137, http://dx.doi.org/10.1016/j.jaad.2025.05.546

Aghajani M; Pham J; Sholji T; Burrell K; Kok C; Frew JW, 2025, 'Originator versus Biosimilar Adalimumab in Hidradenitis Suppurativa: A multi-centre real world analysis of clinical response, maintenance of response and switching', JAAD International, http://dx.doi.org/10.1016/j.jdin.2025.05.023

Tseng H; Frew JW; Murrell DF, 2025, 'Viral Infections as Triggers in Autoimmune Blistering Diseases: A Systematic Review of Associations and Mechanisms', JAAD International, http://dx.doi.org/10.1016/j.jdin.2025.09.007

Frew JW, 2024, 'Intrinsic factors in the pathogenesis of hidradenitis suppurativa: Genetics, hormones, and the microbiome', Journal of the American Academy of Dermatology, 91, pp. S12 - S16, http://dx.doi.org/10.1016/j.jaad.2024.08.052

Pham J; Sholji T; Guttman L; Allan T; Frew JW, 2024, 'Predictors of wound healing after surgical deroofing in Hidradenitis Suppurativa', Australasian Journal of Dermatology, 65, pp. 636 - 641, http://dx.doi.org/10.1111/ajd.14375

Wu K; Larney C; Marshman G; Spelman L; Rubel D; Mcmeniman E; Veysey E; Saunders H; Frew JW, 2024, 'Quality-of-life evaluation in hidradenitis suppurativa in Australia: Validation and outcomes of the HiSQOL questionnaire', Australasian Journal of Dermatology, 65, pp. 630 - 635, http://dx.doi.org/10.1111/ajd.14370

Pham J; Flora A; Guttman L; Allan T; Chandran NS; Frew JW, 2024, 'Response to adalimumab in Caucasian and Asian patients with hidradenitis suppurativa: A retrospective cohort study of an Australian cohort stratified by patient-reported ethnicity', Australasian Journal of Dermatology, 65, pp. 560 - 566, http://dx.doi.org/10.1111/ajd.14343

van As N; Griffin C; Tree A; Patel J; Ostler P; van der Voet H; Loblaw A; Chu W; Ford D; Tolan S; Jain S; Camilleri P; Kancherla K; Frew J; Chan A; Naismith O; Armstrong J; Staffurth J; Martin A; Dayes I; Wells P; Price D; Williamson E; Pugh J; Manning G; Brown S; Burnett S; Hall E, 2024, 'Phase 3 Trial of Stereotactic Body Radiotherapy in Localized Prostate Cancer', NEW ENGLAND JOURNAL OF MEDICINE, 391, pp. 1413 - 1425, http://dx.doi.org/10.1056/NEJMoa2403365

Alavi A; Prens EP; Kimball AB; Frew JW; Krueger JG; Mukhopadhyay S; Gao H; Ranganathan U; Ivanoff NB; Hernandez Daly AC; Zouboulis CC, 2024, 'Proof-of-concept study exploring the effect of spesolimab in patients with moderate-to-severe hidradenitis suppurativa: A randomized double-blind placebo-controlled clinical trial', British Journal of Dermatology, 191, pp. 508 - 518, http://dx.doi.org/10.1093/bjd/ljae144

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