Bio: Dr Joyce Chiu has a long-standing interest in the molecular control of protein functions by redox switches. She developed proteomic methods for detection of redox modifications in proteins and pioneered the discovery of force-redox regulation of integrin de-adhesion in clot formation and inflammation. Her expertise in redox enzymes also contributed to the discovery of a new class of anti-thrombotic compounds and is an inventor of a bioactive factor for bone formation. Joyce's work has been published in the top-tier biomedical journals, including eLife, Blood, and Circulation Research as first, senior or corresponding author. Her contributions to her research field led to the award of the Helen and Robert Ellis Postdoctoral Fellowship (2017-2019) and the Professor Tony Basten Postdoctoral Fellowship (2018) from the Sydney Medical School Foundation. Joyce received the Outstanding Young Scientist Award from the Joint Symposium of the Asian Pacific Society of Thrombosis and Haemostasis and Japanese Society of Thrombosis and Haemostasis in 2021 and an Oral Communication Award from the 15th World Congress on Inflammation in 2022. Joyce was invited to speak at the Gordon Research Seminar for Phagocytes and the NSW Cardiovascular Research Network Rising Stars Seminar Series in 2023. Her research contributions are internationally recognised as evident by her nomination and election to full membership of the prestigious scientific research honour society, Sigma Xi, in 2024. Joyce is currently an editor for the journal, Bio-protocol, and a reviewer for peer-reviewed journals, including Nature Communications, ACS Biochemistry, and Biochemical Pharmacology.

Research interest: Cardiovascular disease is the leading cause of death worldwide, accounting for >30% of all deaths per year. Thrombosis, or clot formation in the arteries or veins, obstructs blood flow and underlies the pathology of heart attack, stroke, and deep vein thrombosis. Using cross-disciplinary approaches, including proteomics, microfluidics, animal models, and computational biology, Joyce discovered novel force-redox mechanisms in clot formation and immune-cell migration. Her current research focuses on (i) the redox control of G protein-coupled receptors in platelets, (ii) the mechanics of immune-cell migration in blood flow, and (iii) the development of novel inhibitors against redox enzymes.