By Scientia Professor Anthony D Kelleher

Journal articles

Venturi V; Chin HY; Asher TE; Ladell K; Scheinberg P; Bornstein E; Van Bockel D; Kelleher AD; Douek DC; Price DA; Davenport MP, 2009, 'TCR β-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV', Journal of Immunology, 181, pp. 7853 - 7862, http://dx.doi.org/10.4049/jimmunol.181.11.7853

Reddy SMR; Center RJ; Suzuki K; Gorry P; Kelleher A; Purcell DF, 2009, 'P12-01. Construction and characterization of recombinant envelope glycoproteins derived from HIV-1 pre-seroconversion strains as potential vaccine immunogens', Retrovirology, 6, pp. P167, http://dx.doi.org/10.1186/1742-4690-6-S3-P167

Reddy SMR; Center RJ; Suzuki K; Gorry P; Kelleher A; Purcell DF, 2009, 'Construction and characterization of recombinant envelope glycoproteins derived from HIV-1 pre-seroconversion strains as potential vaccine immunogens', RETROVIROLOGY, 6, http://dx.doi.org/10.1186/1742-4690-6-S3-P167

Swaminathan S; Zaunders J; Wilkinson J; Suzuki K; Kelleher AD, 2009, 'Does the presence of anti-HIV miRNAs in monocytes explain their resistance to HIV-1 infection?', Blood, 113, pp. 5029 - 5030, http://dx.doi.org/10.1182/blood-2009-01-196741

Munier CM; Zaunders J; Ip S; Cooper DA; Kelleher AD, 2009, 'A culture amplified multi-parametric intracellular cytokine assay (CAMP-ICC) for enhanced detection of antigen specific T-cell responses', Journal of Immunological Methods, 345, pp. 1 - 16

Byakwaga H; Murray JM; Petoumenos K; Kelleher AD; Law MG; Boyd MA; Emery S; Mallon PW; Cooper DA, 2009, 'Evolution of CD4+T cell count in HIV-1-infected adults receiving antiretroviral therapy with sustained long-term virological suppression', AIDS Research and Human Retroviruses, 25, pp. 569 - 576

Zaunders J; Munier ML; Seddiki N; Pett SL; Ip S; Bailey M; Xu Y; Brown KJ; Dyer W; Kim MS; De Rose R; Kent SJ; Jiang L; Breit SN; Emery S; Cunningham AL; Cooper DA; Kelleher AD, 2009, 'High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40)', Journal of Immunology, 183, pp. 2827 - 2836, http://dx.doi.org/10.4049/jimmunol.0803548

Matthews PM; Leslie A; Katzourakis A; Crawford H; Payne R; Prendergast A; Power KA; Kelleher AD; Klenerman P; Carlson J; Heckerman D; Ndung''u T; Walker BD; Allen TM; Pybus O; Goulder PJ, 2009, 'HLA Footprints on human immunodeficiency virus tp 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering', Journal of Virology, 83, pp. 4605 - 4615, http://dx.doi.org/10.1128/JVI.02017-08

Matthews PM; Leslie A; Katzourakis A; Crawford H; Payne R; Prendergast A; Power KA; Kelleher AD; Klenerman P; Carlson J; Heckerman D; Ndung''u T; Walker BD; Allen TM; Pybus O; Goulder PJ, 2009, 'HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering', Journal of Virology, 83, pp. 4605 - 4615, http://jvi.asm.org/content/85/9/4635

Streeck H; Jolin J; Qi YC; Yassine-Diab B; Johnson ; Kwon D; Addo M; Brumme C; Routy J; Little S; Jessen H; Kelleher AD; Hecht FM; Sekaly R; Rosenberg E; Walker BD; Carrington M; Altfeld M, 2009, 'Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells', Journal of Virology, 83, pp. 7641 - 7648

Seddiki N; Sasson SC; Santner-Nanan B; Munier M; Van Bockel DJ; Ip S; Marriott D; Pett SL; Nanan R; Cooper DA; Zaunders J; Kelleher AD, 2009, 'Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease', European Journal of Immunology, 39, pp. 391 - 403, http://dx.doi.org/10.1002/eji.200838630

Yamagishi M; Ishida T; Miyake A; Cooper DA; Kelleher AD; Suzuki K; Watanabe T, 2009, 'Retroviral delivery of promoter-targeted shRNA induces long-term silencing of HIV-1 transcription', Microbes and Infection, 11, pp. 500 - 508

Suzuki K; Kelleher AD, 2009, 'Transcriptional regulation by promoter targeted RNAs', Current Topics in Medicinal Chemistry, 9, pp. 1079 - 1087

Schneidewind A; Brumme Z; Brumme C; Power KA; Reyor L; O Sullivan K; Gladden A; Hempel U; Kuntzen T; Wang YE; Oniangue-Ndza C; Jessen H; Markowitz M; Rosenberg E; Sekaly R; Kelleher AD; Walker BD; Allen TM, 2009, 'Transmission and long-term stability of compensated CD8 escape mutations', Journal of Virology, 83, pp. 3993 - 3997

Weatherall CJ; Kelleher AD; Cooper DA, 2009, 'Trials and tribulations of HIV vaccines', Future Hiv Therapy, 3, pp. 145 - 160

Hamilton AR; Kelleher AD; Marriott D, 2009, 'Unusual association of diseases/symptoms: A case of severe visceral leishmaniasis resulting from travel to Greece', BMJ Case Reports, http://dx.doi.org/10.1136/bcr.06.2009.2036

Pantazis N; Touloumi G; Vanhems P; Gill J; Bucher HC; Porter K; CASCADE Collaboration , 2008, 'The effect of antiretroviral treatment of different durations in primary HIV infection.', AIDS, 22, pp. 2441 - 2450, http://dx.doi.org/10.1097/QAD.0b013e328319ea4e

Pett SL; Zaunders J; Bailey M; Cooper DA; MacRae K; Emery S; Kelleher A, 2008, 'Changes in CCR5+ cells and antigen-specific CD4+ T-cells during monotherapy with a CCR5 antagonist SCH532706 compared with combination therapy', Journal of the International AIDS Society, 11, http://dx.doi.org/10.1186/1758-2652-11-s1-p297

Jarrin I; Geskus R; Bhaskaran K; Prins M; Perez-Hoyos S; Muga R; Hernández-Aguado I; Meyer L; Porter K; Amo JD; Bucher H; Chêne G; Pillay D; Rosinska M; Sabin C; Touloumi G; del Amo J; Pillay D; Sabin C; Touloumi G; Porter K; Walker S; Babiker A; Darbyshire J; de Luca A; Fisher M; Goujard C; Muga R; Kaldor J; Kelleher T; Gelgor L; Ramacciotti T; Cooper D; Smith D; Gill J; Bruun Jørgensen L; Nielsen C; Pedersen C; Lutsar I; Dabis F; Thiebaut R; Masquelier B; Costagliola D; Vanhems P; Boufassa F; Hamouda O; Kucherer C; Pantazis N; Hatzakis A; Paraskevis D; Karafoulidou A; Rezza G; Dorrucci M; Longo B; Balotta C; van Asten L; van der Bij A; Coutinho R; Sannes M; Brubakk O; Eskild A; Bruun JN; Camacho R; Smolskaya T; Tor J; de Olalla PG; Caylà J; del Romero J; Belda J; Rickenbach M; Francioli P; Malyuta R; Brettle R; Delpech V; Lattimore S; Murphy G; Parry J; Gill N; Lee C; Johnson A; Phillips A; Babiker A, 2008, 'Gender differences in HIV progression to AIDS and death in industrialized countries: Slower disease progression following HIV seroconversion in women', American Journal of Epidemiology, 168, pp. 532 - 540, http://dx.doi.org/10.1093/aje/kwn179

Bhaskaran K; Hamouda O; Sannes M; Boufassa F; Johnson AM; Lambert PC; Porter K; CASCADE Collaboration , 2008, 'Changes in the risk of death after HIV seroconversion compared with mortality in the general population.', JAMA, 300, pp. 51 - 59, http://dx.doi.org/10.1001/jama.300.1.51

Seddiki N; Kelleher AD, 2008, 'Regulatory T cells in HIV infection: Who's suppressing what?', Current Infectious Disease Reports, 10, pp. 252 - 258, http://dx.doi.org/10.1007/s11908-008-0041-8

Seddiki N; Kelleher AD, 2008, 'Regulatory T cells in HIV infection: Who's suppressing what?', Current HIV AIDS Reports, 5, pp. 20 - 26, http://dx.doi.org/10.1007/s11904-008-0004-6

McElrath MJ; De Rosa SC; Moodie Z; Dubey S; Kierstead L; Janes H; Defawe OD; Carter DK; Hural J; Akondy R; Buchbinder SP; Robertson MN; Mehrotra DV; Self SG; Corey L; Shiver JW; Casimiro DR, 2008, 'HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis', Lancet, 372, pp. 1894 - 1905, http://dx.doi.org/10.1016/S0140-6736(08)61592-5

Santner-Nanan B; Seddiki N; Zhu E; Quent V; Kelleher AD; Fazekas de St Groth B; Nanan R, 2008, 'Accelerated age-dependent transition of human regulatory T cells to effector memory phenotype', International Immunology, 20, pp. 375 - 383, http://dx.doi.org/10.1093/intimm/dxm151

Suzuki K; Juelich T; Lim H; Ishida T; Watanebe T; Cooper DA; Rao S; Kelleher AD, 2008, 'Closed chromatin architecture is induced by an RNA duplex targeting the HIV-1 promoter region', The Journal of Biological Chemistry, 283, pp. 23353 - 23363

Kelleher AD; Purcell D, 2008, 'Controlling HIV infection HIV co-receptor gets the finger', Immunology and Cell Biology, 86, pp. 641 - 642

Mallon PW; Sedwell R; Rogers GJ; Nolan D; Unemori P; Hoy JF; Samaras K; Kelleher AD; Emery S; Cooper DA; Carr AD, 2008, 'Effect of Rosiglitazone on Peroxisome Proliferator-Activated Receptor gamma Gene Expression in Human Adipose Tissue Is Limited by Antiretroviral Drug-Induced Mitochondrial Dysfunction', Journal of Infectious Diseases, 198, pp. 1794 - 1803

Chessman D; Kostenko L; Lethborg T; Purcell A; Williamson N; Chen Z; Kjer-Nielsen L; Mifsud N; Tait B; Holdsworth R; Almeida C; Nolan D; Macdonalds W; Archbold J; Kelleher AD; Marriott D; Mallal SA; Bharadwaj M; Rossjohn J; McCluskey J, 2008, 'Human leukocyte antigen class I-restricted activation of CD8(+) T cells provides the immunogenetic basis of a systemic drug hypersensitivity', Immunity, 28, pp. 822 - 832, http://dx.doi.org/10.1016/j.immuni.2008.04.020

Mason R; De Rose R; Seddiki N; Kelleher AD; Kent SJ, 2008, 'Low pre-infection levels and loss of central memory CD4+T cells may predict rapid progression in SIV-infected pigtail macaques', Virology, 381, pp. 11 - 15

Brumme Z; Brumme C; Carlson J; Streeck H; John M; Eichbaum Q; Block B; Baker B; Kadie C; Markowitz M; Jessen H; Kelleher AD; Rosenberg E; Kaldor JM; Yuki Y; Carrington M; Allen TM; Mallal SA; Altfeld M; Heckerman D; Walker BD, 2008, 'Marked epitope- and allele- specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection', Journal of Virology, 82, pp. 9216 - 9227

Lim H; Suzuki K; Cooper DA; Kelleher AD, 2008, 'Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro', Molecular Therapy, 16, pp. 565 - 570, http://dx.doi.org/10.1038/sj.mt.6300380

Seddiki N; Kelleher AD, 2008, 'Regulatory T cell abnormalities are associated with aberrant CD4+ T cell responses in patients with immune inflammatory syndrome (IRIS)', Clinical Immunology, 127, pp. S126 - S127, http://dx.doi.org/10.1016/j.ctim.2008.03.359

Burton C; Goodall R; Samri A; Autran B; Kelleher AD; Poli G; Pantaleo G; Gotch F; Imami N, 2008, 'Restoration of anti-tetanus toxoid responses in patients initiating highly active antiretroviral therapy with or without a boost immunization: an INITIO substudy', Clinical and Experimental Immunology, 152, pp. 252 - 257, http://dx.doi.org/10.1111/j.1365-2249.2008.03611.x

De Rose R; Mason RS; Loh L; Peut V; Smith MZ; Fernandez CS; Alcantara S; amarasena T; Reece J; Seddiki N; Kelleher AD; Zaunders J; Kent SJ, 2008, 'Safety, immunogenicity and efficacy of peptide-pulsed cellular immunotherapy in macaques.', Journal of Medical Primatology, 37, pp. 69 - 78

Streeck H; Van Bockel DJ; Kelleher AD, 2008, 'T-cell responses in primary HIV-1 infection. .', Current opinion in HIV & AIDS, 3, pp. 52 - 59

Venturi V; Chin HY; Asher TE; Ladell K; Scheinberg P; Bornstein E; van Bockel D; Kelleher AD; Douek DC; Price DA; Davenport MP, 2008, 'TCR beta-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV', Journal of Immunology, 181, pp. 7853 - 7862

Falster KA; Gelgor L; Shaik A; Zablotska Manos I; Prestage G; Grierson J; Thorpe R; Pitts M; Anderson JS; Chuah J; Mulhall BP; Petoumenos K; Kelleher AD; Law MG, 2008, 'Trends in antiretroviral treatment use and treatment response in three Australian states in the first decade of combination antiretroviral treatment', Sexual Health, 5, pp. 141 - 154

Lewin S; Murray JM; Solomon A; Wightman F; Cameron P; Purcell DJ; Zaunders J; Grey PA; Bloch M; Smith DE; Cooper DA; Kelleher AD, 2008, 'Virologic determinants of success after structured treatment interruptions in antiretrovirals in acute HIV-1 infection', JAIDS: Journal of Acquired Immune Deficiency Syndromes, 47, pp. 140 - 147

Zaunders J; Jing J; Leipold M; Maecker H; Kelleher AD; Koch I, 2007, 'Computationally efficient multidimensional analysis of complex flow cytometry data using second order polynomial histograms', Cytometry Part A, 89, pp. 44 - 58, http://dx.doi.org/10.1002/cyto.a.22704

Munier CM; Kelleher AD, 2007, 'Acutely dysregulated, chronically disabled by the enemy within: T-cell responses to HIV-1 infection', Immunology and Cell Biology, 85, pp. 6 - 15

Murray JM; Emery S; Kelleher AD; Law MG; Chen J; Hazuda DJ; Nguyen BT; Teppler H; Cooper DA, 2007, 'Antiretroviral therapy with the integrase inhibitor raltegravir alters decay kinetics of HIV, significantly reducing the second phase', AIDS, 21, pp. 2315 - 2321

Schneidewind A; Brockman M; Yang R; Adam RI; Li B; Le Gall S; Rinaldo C; Craggs SL; Allgaier RL; Power KA; Kuntzen T; Tung C; LaBute MX; Mueller SC; Harrer T; Mcmichael AJ; Goulder PJ; Aiken CM; Brander C; Kelleher AD; Allen TM, 2007, 'Escape from the Dominant HLA-B27-Restricted Cytotoxic T-Lymphocyte Response in Gag Is Associated with a Dramatic Reduction in Human Immunodeficiency Virus Type 1 Replication', Journal of Virology, 81, pp. 12382 - 12393

Emery S; Kelleher AD; Workman C; Puls R; Bloch MT; Baker D; Hoy JF; Ip S; Nalliah K; Ward L; Law MG; Cooper DA, 2007, 'Influence of IFN gamma co-expression on the safety and antiviral efficacy of recombinant fowlpox virus HIV therapeutic vaccines following interruption of antiretroviral therapy', Human Vaccines, 3, pp. 260 - 267

Lin BB; Gladden A; Altfeld M; Kaldor JM; Cooper DA; Kelleher AD; Allen TM, 2007, 'Rapid Reversion of Sequence Polymorphisms Dominates Early Human Immunodeficiency Virus Type 1 Evolution', Journal of Virology, 81, pp. 193 - 201

Streeck H; Lichterfeld M; Alter G; Meier A; Teigen N; Yassine-Diab B; Sidhu H; Little S; Kelleher AD; Routy J; Rosenberg E; Sekaly R; Walker BD; Altfeld M, 2007, 'Recognition of a defined region within p24 Gag by CD8(+) T cells during primary human immunodeficiency virus type I infection in individuals expressing protective HLA class I alleles', Journal of Virology, 81, pp. 7725 - 7731

Dyer W; Pett SL; Sullivan JS; Emery S; Cooper DA; Kelleher AD; Lloyd AR; Lewin S, 2007, 'Substantial improvements in performance indicators achieved in a peripheral blood mononuclear cell cryopreservation quality assurance program using single donor samples', Clinical and Vaccine Immunology, 14, pp. 52 - 59

Venturi V; Chin H; Asher T; Ladell K; Scheinberg P; Bornstein E; Van Bockel DJ; Kelleher AD; Douek DC; Price DA; Davenport MP, 2007, 'T cell receptor b-chain sharing in human CD8+ T cell responses to cytomegalovirus and Epstein-Barr virus', Journal of Immunology, 181, pp. 7853 - 7862

Samri A; Goodall RL; Burton C; Imami N; Pantaleo G; Kelleher AD; Poli G; Gotch F; Autran B, 2007, 'Three-year immune reconstitution in PI-sparing and PI-containing antiretroviral regimens in advanced HIV-1 disease', Antiviral Therapy, 12, pp. 553 - 558

Kaufmann D; Kavanagh D; Pereyra F; Zaunders J; Mackey E; Miura T; Palmer S; Brockman M; Rathod A; Piechocka-Trocha A; Baker B; Zhu B; Le Gall S; Waring M; Ahern R; Moss K; Kelleher AD; Coffin J; Freeman G; Rosenberg E; Walker BD, 2007, 'Upregulation of CTLA-4 by HIV-specific CD4(+) T cells correlates with disease progression and defines a reversible immune dysfunction', Nature Immunology, 8, pp. 1246 - 1254

van Bockel D; Price DA; Asher TE; Venturi V; Suzuki K; Warton K; Davenport MP; Cooper DA; Douek DC; Kelleher AD, 2007, 'Validation of RNA-based molecular clonotype analysis for virus-specific CD8+ T-cells in formaldehyde-fixed specimens isolated from peripheral blood', Journal of Immunological Methods, 326, pp. 127 - 138, http://dx.doi.org/10.1016/j.jim.2007.07.016

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