By Professor William Arthur Sewell

Journal articles

Guillod P; Savvas A; Robinson PN; Nai D; Naresh KN; Ott G; Schuh A; Sewell WA; Anderson M; Matentzoglu N; Durgavarjhula D; Xu ML; Druzdzel MJ; Astle JM, 2025, 'A Systematic Approach to Prioritise Diagnostically Useful Findings for Inclusion in Electronic Health Records as Discrete Data to Improve Clinical Artificial Intelligence Tools and Genomic Research', Clinical Oncology, 39, http://dx.doi.org/10.1016/j.clon.2024.103737

Jeffrey B; Alves M; Le S; Foley E; Breit S; Sewell W, 2025, 'Tricky Ts: TRBC2 in the assessment of T cell lymphoproliferative disease by flow cytometry', Pathology, 57, pp. S26 - S26, http://dx.doi.org/10.1016/j.pathol.2024.12.124

Ho J; Walter S; Alvarado R; Grayson JW; Campbell RG; Kalish LH; Sacks R; Sewell WA; Rimmer J; Harvey RJ, 2024, 'Clinical features of responders to mepolizumab in eosinophilic chronic rhinosinusitis and the outcomes post treatment cessation', Australian Journal of Otolaryngology, 7, pp. 17 - 17, http://dx.doi.org/10.21037/ajo-23-28

Trapani D; Garcia PJ; Schroeder L; Abdul-Ghani R; Hansali A; Offutalu PN; Sewell W; Shakoor S; Yunfeng L; Hashimoto N; Moussy FG; Aceves Capri A; Fleming K, 2024, 'WHO model list of essential in vitro diagnostics: strengthening diagnostics capacity to transform health care for all', Lancet Global Health, 12, pp. e364 - e365, http://dx.doi.org/10.1016/S2214-109X(23)00568-5

Pathmanandavel K; Le S; Xie S; Alves M; Foley E; Kelleher A; Zaunders J; Carr A; Tong W; Breit S; Sewell W; Kane A, 2024, 'Novel clinical applications of functional assays to measure antigen-specific cellular immunity', Pathology, 56, pp. s27, http://dx.doi.org/10.1016/j.pathol.2023.12.101

Peng D; Kodituwakku A; Le S; Smith SABC; Qiu MR; Earls P; Field AS; Parker AJC; Law M; Milliken ST; Sewell WA, 2023, 'Factors determining whether diffuse large B-cell lymphoma samples are detected by flow cytometry', International Journal of Laboratory Hematology, 45, pp. 927 - 934, http://dx.doi.org/10.1111/ijlh.14158

Alaggio R; Amador C; Anagnostopoulos I; Attygalle AD; de Oliveira Araujo IB; Berti E; Bhagat G; Borges AM; Boyer D; Calaminici M; Chadburn A; Chan JKC; Cheuk W; Chng WJ; Choi JK; Chuang SS; Coupland SE; Czader M; Dave SS; de Jong D; Di Napoli A; Du MQ; Elenitoba-Johnson KS; Ferry J; Geyer J; Gratzinger D; Guitart J; Gujral S; Harris M; Harrison CJ; Hartmann S; Hochhaus A; Jansen PM; Karube K; Kempf W; Khoury J; Kimura H; Klapper W; Kovach AE; Kumar S; Lazar AJ; Lazzi S; Leoncini L; Leung N; Leventaki V; Li XQ; Lim MS; Liu WP; Louissaint A; Marcogliese A; Medeiros LJ; Michal M; Miranda RN; Mitteldorf C; Montes-Moreno S; Morice W; Nardi V; Naresh KN; Natkunam Y; Ng SB; Oschlies I; Ott G; Parrens M; Pulitzer M; Rajkumar SV; Rawstron AC; Rech K; Rosenwald A; Said J; Sarkozy C; Sayed S; Saygin C; Schuh A; Sewell W; Siebert R; Sohani AR; Suzuki R; Tooze R; Traverse-Glehen A; Vega F; Vergier B; Wechalekar AD; Wood B; Xerri L; Xiao W; Akinola NO; Akkari Y; Allende LM; Aozasa K; Arcaini L; Ardeshna KM; Asano N; Attarbaschi A; Bacon CM; Barrans SL; Batchelor T; Battistella M; Baughn LB; Behdad A; Berentsen S, 2023, 'Correction: “The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms” Leukemia. 2022 Jul;36(7):1720–1748 (Leukemia, (2022), 36, 7, (1720-1748), 10.1038/s41375-022-01620-2)', Leukemia, 37, pp. 1944 - 1951, http://dx.doi.org/10.1038/s41375-023-01962-5

Sit A; Alvarado R; Earls P; Rimmer J; Kalish L; Campbell R; Sewell W; Harvey RJ, 2023, 'CCAD or eCRS: Defining Eosinophilic Subpopulations in Chronic Rhinosinusitis', American Journal of Rhinology and Allergy, 37, pp. 402 - 409, http://dx.doi.org/10.1177/19458924231155012

Nguyen T; Lau A; Bier J; Cooke KC; Lenthall H; Ruiz-Diaz S; Avery DT; Brigden H; Zahra D; Sewell WA; Droney L; Okada S; Asano T; Abolhassani H; Chavoshzadeh Z; Abraham RS; Rajapakse N; Klee EW; Church JA; Williams A; Wong M; Burkhart C; Uzel G; Croucher DR; James DE; Ma CS; Brink R; Tangye SG; Deenick EK, 2023, 'Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2', The Journal of experimental medicine, 220, pp. e20221020, http://dx.doi.org/10.1084/jem.20221020

Alaggio R; Amador C; Anagnostopoulos I; Attygalle AD; Araujo IBDO; Berti E; Bhagat G; Borges AM; Boyer D; Calaminici M; Chadburn A; Chan JKC; Cheuk W; Chng WJ; Choi JK; Chuang SS; Coupland SE; Czader M; Dave SS; de Jong D; Du MQ; Elenitoba-Johnson KS; Ferry J; Geyer J; Gratzinger D; Guitart J; Gujral S; Harris M; Harrison CJ; Hartmann S; Hochhaus A; Jansen PM; Karube K; Kempf W; Khoury J; Kimura H; Klapper W; Kovach AE; Kumar S; Lazar AJ; Lazzi S; Leoncini L; Leung N; Leventaki V; Li XQ; Lim MS; Liu WP; Louissaint A; Marcogliese A; Medeiros LJ; Michal M; Miranda RN; Mitteldorf C; Montes-Moreno S; Morice W; Nardi V; Naresh KN; Natkunam Y; Ng SB; Oschlies I; Ott G; Parrens M; Pulitzer M; Rajkumar SV; Rawstron AC; Rech K; Rosenwald A; Said J; Sarkozy C; Sayed S; Saygin C; Schuh A; Sewell W; Siebert R; Sohani AR; Tooze R; Traverse-Glehen A; Vega F; Vergier B; Wechalekar AD; Wood B; Xerri L; Xiao W, 2022, 'The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms', Leukemia, 36, pp. 1720 - 1748, http://dx.doi.org/10.1038/s41375-022-01620-2

Khoury JD; Solary E; Abla O; Akkari Y; Alaggio R; Apperley JF; Bejar R; Berti E; Busque L; Chan JKC; Chen W; Chen X; Chng WJ; Choi JK; Colmenero I; Coupland SE; Cross NCP; De Jong D; Elghetany MT; Takahashi E; Emile JF; Ferry J; Fogelstrand L; Fontenay M; Germing U; Gujral S; Haferlach T; Harrison C; Hodge JC; Hu S; Jansen JH; Kanagal-Shamanna R; Kantarjian HM; Kratz CP; Li XQ; Lim MS; Loeb K; Loghavi S; Marcogliese A; Meshinchi S; Michaels P; Naresh KN; Natkunam Y; Nejati R; Ott G; Padron E; Patel KP; Patkar N; Picarsic J; Platzbecker U; Roberts I; Schuh A; Sewell W; Siebert R; Tembhare P; Tyner J; Verstovsek S; Wang W; Wood B; Xiao W; Yeung C; Hochhaus A, 2022, 'The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms', Leukemia, 36, pp. 1703 - 1719, http://dx.doi.org/10.1038/s41375-022-01613-1

Pembroke JS; Joseph JE; Smith SABC; Parker AJC; Jiang W; Sewell WA, 2022, 'Comparison of flow cytometry with other modalities in the diagnosis of myelodysplastic syndrome', International Journal of Laboratory Hematology, 44, pp. 313 - 319, http://dx.doi.org/10.1111/ijlh.13771

Sabroe RA; Lawlor F; Grattan CEH; Ardern-Jones MR; Bewley A; Campbell L; Flohr C; Leslie TA; Marsland AM; Ogg G; Sewell WAC; Hashme M; Exton LS; Mohd Mustapa MF; Ezejimofor MC, 2022, 'British Association of Dermatologists guidelines for the management of people with chronic urticaria 2021*', British Journal of Dermatology, 186, pp. 398 - 413, http://dx.doi.org/10.1111/bjd.20892

Ho J; Alvarado R; Rimmer J; Sewell WA; Walter S; Earls P; Campbell RG; Sacks R; Kalish LH; Harvey RJ, 2022, 'Comparison of Sinonasal Histopathological Changes in Biological Treatment of Eosinophilic Chronic Rhinosinusitis', American Journal of Rhinology and Allergy, 36, pp. 72 - 80, http://dx.doi.org/10.1177/19458924211021031

Ayton T; Cherepanoff S; Gottlieb D; Sewell WA; Smith S; Hooper C, 2021, 'Intraocular solitary extramedullary plasmacytoma presenting as unilateral anterior and intermediate uveitis preceded by refractory glaucoma', BMC Ophthalmology, 21, pp. 66, http://dx.doi.org/10.1186/s12886-021-01822-9

Yap JY; Moens L; Lin MW; Kane A; Kelleher A; Toong C; Wu KHC; Sewell WA; Phan TG; Hollway GE; Enthoven K; Gray PE; Casas-Martin J; Wouters C; De Somer L; Hershfield M; Bucciol G; Delafontaine S; Ma CS; Tangye SG; Meyts I, 2021, 'Intrinsic Defects in B Cell Development and Differentiation, T Cell Exhaustion and Altered Unconventional T Cell Generation Characterize Human Adenosine Deaminase Type 2 Deficiency', Journal of Clinical Immunology, 41, pp. 1915 - 1935, http://dx.doi.org/10.1007/s10875-021-01141-0

Russell AJ; Gray PE; Ziegler JB; Kim YJ; Smith S; Sewell WA; Goodnow CC, 2021, 'SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression', Proceedings of the National Academy of Sciences of the United States of America, 118, pp. e2110190118, http://dx.doi.org/10.1073/pnas.2110190118

Li W; Ho J; Grayson JW; Alvarado R; Rimmer J; Sewell WA; Campbell R; Kalish L; Sacks R; Harvey RJ, 2021, 'Evaluation of Diffuse Type 2 Dominant or Eosinophilic Chronic Rhinosinusitis with Corticosteroid Irrigation after Surgical Neosinus Cavity Formation', JAMA Otolaryngology Head and Neck Surgery, 147, pp. 360 - 367, http://dx.doi.org/10.1001/jamaoto.2020.5286

Ho J; Li W; Grayson JW; Alvarado R; Rimmer J; Sewell WA; Harvey RJ, 2021, 'Systemic medication requirement in post-surgical patients with eosinophilic chronic rhinosinusitis*', Rhinology, 59, pp. 59 - 65, http://dx.doi.org/10.4193/Rhin20.073

Paterson JA; Hwang A; Wong S; Sewell W; Joseph JE; Hamad N, 2020, 'Two Rare Cases of Severe Autoimmune Dyserythropoiesis without Any Underlying Haematological Malignancy or Autoimmune Disease', BLOOD, 136, http://dx.doi.org/10.1182/blood-2020-142281

Grayson JW; Li W; Ho J; Alvarado R; Rimmer J; Sewell WA; Harvey RJ, 2020, 'Topography of polyp recurrence in eosinophilic chronic rhinosinusitis', International Forum of Allergy and Rhinology, 10, pp. 604 - 609, http://dx.doi.org/10.1002/alr.22529

Hamizan AW; Azer M; Alvarado R; Earls P; Barham HP; Tattersall J; Rimmer J; Kalish L; Sewell WA; Harvey R, 2019, 'The Distinguishing Clinical Features of Nonallergic Rhinitis Patients', American Journal of Rhinology and Allergy, 33, pp. 524 - 530, http://dx.doi.org/10.1177/1945892419850750

Ho J; Alvarado R; Rimmer J; Sewell WA; Harvey RJ, 2019, 'Atopy in chronic rhinosinusitis: impact on quality of life outcomes', International Forum of Allergy and Rhinology, 9, pp. 501 - 507, http://dx.doi.org/10.1002/alr.22272

Hamizan A; Alvarado R; Rimmer J; Sewell WA; Barham HP; Kalish L; Harvey R, 2019, 'Nasal mucosal brushing as a diagnostic method for allergic rhinitis', Allergy and Asthma Proceedings, 40, pp. 167 - 172, http://dx.doi.org/10.2500/aap.2019.40.4209

Hamizan AW; Rimmer J; Alvarado R; Sewell WA; Tatersall J; Barham HP; Kalish L; Harvey RJ, 2019, 'Turbinate-Specific IgE in Normal and Rhinitic Patients', American Journal of Rhinology and Allergy, 33, pp. 178 - 183, http://dx.doi.org/10.1177/1945892418825224

Hamizan AW; Rimmer J; Husain S; Alvarado R; Tatersall J; Sewell W; Kalish L; Harvey RJ, 2019, 'Local specific immunoglobulin E among patients with non-allergic rhinitis: A systematic review', Rhinology, 57, pp. 10 - 20, http://dx.doi.org/10.4193/Rhin18.074

Ting YS; Smith SABC; Brown DA; Dodds AJ; Fay KC; Ma DDF; Milliken S; Moore JJ; Sewell WA, 2018, 'CD200 is a useful diagnostic marker for identifying atypical chronic lymphocytic leukemia by flow cytometry', International Journal of Laboratory Hematology, 40, pp. 533 - 539, http://dx.doi.org/10.1111/ijlh.12857

Avery DT; Kane A; Nguyen T; Lau A; Nguyen A; Lenthall H; Payne K; Shi W; Brigden H; French E; Bier J; Hermes JR; Zahra D; Sewell WA; Butt D; Elliott M; Boztug K; Meyts I; Choo S; Hsu P; Wong M; Berglund LJ; Gray P; O’Sullivan M; Cole T; Holland SM; Ma CS; Burkhart C; Corcoran LM; Phan TG; Brink R; Uzel G; Deenick EK; Tangye SG; Bier Nogueira J, 2018, 'Germline-activating mutations in PIK3CD compromise B cell development and function', Journal of Experimental Medicine, 215, pp. 2073 - 2095, http://dx.doi.org/10.1084/jem.20180010

Saricilar EC; Hamizan A; Alvarado R; Rimmer J; Sewell W; Tatersall J; Barham HP; Harvey R, 2018, 'Optimizing Protein Harvest From Nasal Brushings for Determining Local Allergy Responses', American Journal of Rhinology and Allergy, 32, pp. 244 - 251, http://dx.doi.org/10.1177/1945892418777668

Ho J; Hamizan AW; Alvarado R; Rimmer J; Sewell WA; Harvey RJ, 2018, 'Systemic Predictors of Eosinophilic Chronic Rhinosinusitis', American Journal of Rhinology and Allergy, 32, pp. 252 - 257, http://dx.doi.org/10.1177/1945892418779451

Deenick EK; Morey A; Danta M; Emmett L; Fay K; Gracie G; Ma CS; Macintosh R; Smith SABC; Sasson SC; Sewell WA; Cowley M; Tangye SG; Kelleher AD; Phan TG, 2018, 'Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency', Journal of Clinical Immunology, 38, pp. 159 - 162, http://dx.doi.org/10.1007/s10875-018-0477-z

Hamizan AW; Rimmer J; Alvarado R; Sewell WA; Kalish L; Sacks R; Harvey RJ, 2017, 'Positive allergen reaction in allergic and nonallergic rhinitis: a systematic review', International Forum of Allergy and Rhinology, 7, pp. 868 - 877, http://dx.doi.org/10.1002/alr.21988

Tran DN; Smith SABC; Brown DA; Parker AJC; Joseph JE; Armstrong N; Sewell WA, 2017, 'Polychromatic flow cytometry is more sensitive than microscopy in detecting small monoclonal plasma cell populations', Cytometry Part B Clinical Cytometry, 92, pp. 136 - 144, http://dx.doi.org/10.1002/cyto.b.21401

Christensen JM; Cheng J; Earls P; Gunton J; Sewell W; Sacks R; Harvey RJ, 2017, 'Vitamin D pathway regulatory genes encoding 1α-hydroxylase and 24-hydroxylase are dysregulated in sinonasal tissue during chronic rhinosinusitis', International Forum of Allergy and Rhinology, 7, pp. 169 - 176, http://dx.doi.org/10.1002/alr.21852

Sasson SC; McGill K; Wienholt L; Carr A; Brown DA; Kelleher AD; Breit SN; Sewell WA, 2015, 'Comparison of the Freelite serum free light chain (SFLC) assay with serum and urine electrophoresis/immunofixation and the N Latex FLC assay', Pathology, 47, pp. 564 - 569, http://dx.doi.org/10.1097/PAT.0000000000000316

Sasson SC; Smith SA; Qiu MR; Stone ECA; Sewell WA, 2015, 'Monoclonal precursor T-cell infiltrate in recurrent thymoma: a case report', Pathology, 47, pp. 375 - 377, http://dx.doi.org/10.1097/PAT.0000000000000257

Lam M; Hull L; Imrie A; Snidvongs K; Chin D; Pratt E; Kalish L; Sacks R; Earls P; Sewell W; Harvey RJ, 2015, 'Interleukin-25 and interleukin-33 as mediators of eosinophilic inflammation in chronic rhinosinusitis', American Journal of Rhinology and Allergy, 29, pp. 175 - 181, http://dx.doi.org/10.2500/ajra.2015.29.4176

Ho J; Bailey M; Zaunders J; Mrad N; Sacks R; Sewell W; Harvey RJ, 2015, 'Cellular comparison of sinus mucosa vs polyp tissue from a single sinus cavity in chronic rhinosinusitis', International Forum of Allergy & Rhinology, 5, pp. 14 - 27, http://dx.doi.org/10.1002/alr.21417

Ho J; Bailey M; Zaunders J; Mrad N; Sacks R; Sewell W; Harvey RJ, 2015, 'Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia', Clinical & Experimental Allergy, 45, pp. 394 - 403, http://dx.doi.org/10.1111/cea.12462

Tran D; Smith S; Brown D; Sewell W, 2015, 'Immunophenotyping of plasma cell and the utility of flow cytometry in plasma cell dyscrasias', Pathology, 47, pp. S94 - S95, http://dx.doi.org/10.1097/01.pat.0000461602.22967.40

Sasson SC; McGill K; Wienholt L; Carr A; Brown D; Kelleher AD; Breit SN; Sewell WA, 2015, 'Retrospective audit of the freeliteTM serum free light chain (SFLC) assay: testing patterns, concordance with serum and urine electrophoresis/immunofixation and correlation with the N latex FLC assay', Pathology, 47, pp. S94 - S94, http://dx.doi.org/10.1097/01.pat.0000461601.28805.d5

Swift J; Saing S; Rouet R; Dudgeon K; Schofield P; Sewell W; Christ D; James L, 2014, 'Identification of aggregation inhibitors of the human antibody light chain repertoire by phage display', Protein Engineering Design and Selection, 27, pp. 405 - 409, http://dx.doi.org/10.1093/protein/gzu026

Sasson S; Smith S; Sewell WA; Morey A; Danta M; Emmett L; Kelleher AD; Fay K; Phan T, 2014, 'MONOCLONAL B-CELL POPULATION OF INDETERMINANT MALIGNANT POTENTIAL IN THE SETTING OF ATYPICAL CVID ASSOCIATED WITH LYMPHADENOPATHY AND SPLENOMEGALY', INTERNAL MEDICINE JOURNAL, 44, pp. 33 - 33, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342722800109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Wang Y; Jackson KJL; Davies J; Chen Z; Gaeta BA; Rimmer J; Sewell WA; Collins AM, 2014, 'IgE-associated IGHV genes from venom and peanut allergic individuals lack mutational evidence of antigen selection', Plos One, 9, http://dx.doi.org/10.1371/journal.pone.0089730

Sewell WA, 2014, 'Flow cytometry - clinical cases', Pathology, 46, pp. S37 - S37, http://dx.doi.org/10.1097/pat.0000000000000059

Agrawal S; Smith SABC; Tangye SG; Sewell WA, 2013, 'Transitional B cell subsets in human bone marrow', Clinical and Experimental Immunology, 174, pp. 53 - 59, http://dx.doi.org/10.1111/cei.12149

Fisher VJ; Sewell WA; Holding S, 2013, '922 Predictive Value of Anti-Mitochondrial Antibodies for Development of Cholestasis and Primary Biliary Cirrhosis', Gastroenterology, 144, pp. S - 966, http://dx.doi.org/10.1016/s0016-5085(13)63588-x

Lam M; Hull L; McLachlan RH; Snidvongs K; Chin D; Pratt E; Kalish LH; Sacks R; Earls P; Sewell WA; Harvey RJ, 2013, 'Clinical severity and epithelial endotypes in chronic rhinosinusitis', International Forum of Allergy and Rhinology, 3, pp. 121 - 128, http://dx.doi.org/10.1002/alr.21082

Fuller T; Kodituwakku A; Smith S; Earls P; Sewell W, 2013, 'Correlation of flow cytometric and cytological analysis of fine needle aspirates in the diagnosis of haematological malignancies', Pathology, 45, pp. S97 - S97, http://dx.doi.org/10.1097/01.pat.0000426993.90859.bc

Jackson KJ; Wang Y; Gaeta BA; Pomat W; Siba PM; Sewell WA; Collins AM, 2012, 'Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells', Immunogenetics, 64, pp. 3 - 14, http://dx.doi.org/10.1007/s00251-011-0559-z

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