By Professor Peter Gunning

Conference Abstracts

Rynkiewicz M; Stehn J; Gunning P; Lehman W, 2014, 'Structure of the Anti-Cancer Compound TR100 Target-Sites on Tpm3.1 Tropomyosin', in BIOPHYSICAL JOURNAL, CELL PRESS, CA, San Francisco, Vol. 112, pp. 560A - 560A, presented at 58th Annual Meeting of the Biophysical-Society, CA, San Francisco, 15 February 2014 - 19 February 2014, http://dx.doi.org/10.1016/j.bpj.2016.11.3019

Kee AJ; Tran L; Yang L; Genel F; Weigert R; Gunning P; Hardeman E, 2013, 'Identification of a novel Golgi-associated actin filament population that is important for maintaining Golgi morphology', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348702023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Stehn JR; Haass NK; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Han MH; Hill TA; McCluskey A; Palmer S; Hardeman EC; Weninger W; Cripe TR; Gunning P, 2012, 'Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1827

Segueira VB; Stehn JR; Haass N; Bonello T; Guven K; Desouza M; Schevzov G; Kottyan G; McCluskey A; Bischof L; Palmer S; Hardeman EC; Allanson M; Reeve V; Weninger W; Cripe TP; Gunning P, 2012, 'Improving the specificity of drugs which target the actin cytoskeleton for cancer therapy', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-5230

Maytum R; Gunning P; Lin J; Copeland O; Bayliss C; Marston S, 2011, 'Analysis of Tropomyosin (Tm) Isoforms in Heart Muscle by LC/MS and Western Blotting Demonstrates Previously Uncharacterised High-Level Expression of gamma Tm', in BIOPHYSICAL JOURNAL, CELL PRESS, MD, Baltimore, Vol. 100, pp. 371 - 371, presented at 55th Annual Meeting of the Biophysical-Society, MD, Baltimore, 05 March 2011 - 09 March 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306288603140&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Gunning P; Weinberger R; Schevzov G; Percival J; Hannan A; Dufour C; Qin H; Ferguson V; Jeffrey P, 1996, 'Spatial segregation of microfilament isoforms in neurons and cycling fibroblasts.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 7, pp. 1972 - 1972, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996WB01801969&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Patents

Gunning P; Stehn J; McCluskey A; Butler T; Dixon I, 2007, Compounds for treating Cancer, Australia, Patent No. Australian Provisional Patent Application No 2007906570

Gunning P; Stehn J; Schevzov G, 2005, Identification of compounds for the treatment of proliferative disorders, Australia, Patent No. Australian Provisional Patent Application No 2004906888

Preprints

Latham SL; O’Donnell YEI; Girgis-Cook O; Clearwater MS; Bryce NS; Mok ETY; Lynn SA; Ni J; Alfred S; Leong KH; Quek L-E; Murphy KJ; Pantarelli C; Dragutinovic I; Naeini MM; Thiel C; Cadell A; Phimmachanh M; Sharma R; Millar E; Han JZR; Hastings JF; Köhler M; Brummer T; Young A; O’Toole S; Oakes SR; Hardeman E; Lock J; Kolch W; Taft MH; Nobis M; Goldstein L; Timpson P; Parker BL; Holst J; Gunning PW; Cox TR; Morris JC; Croucher DR, 2025, A selective inhibitor of oncogenic JNK signalling perturbs metastatic outgrowth of triple-negative breast cancer through metabolic blockade, http://dx.doi.org/10.1101/2025.04.16.649243

Genoud S; Chaichim C; Porto RR; Tomanic T; Stefen H; Paric E; Sarkar S; Yoo D; Gao W; Hardeman EC; Gunning PW; Karl T; Power J; Fath T, 2025, Knock-out of Tpm4.2/actin filaments alters neuronal signaling, neurite outgrowth and behavioral phenotypes in mice, http://dx.doi.org/10.1101/2025.04.10.648285

Gan WJ; Giri R; Begun J; Abud HE; Hardeman EC; Gunning PW; Yap AS; Noordstra I, 2024, A truncation mutant of adenomatous polyposis coli (APC) impairs apical cell extrusion through elevated epithelial tissue tension, http://dx.doi.org/10.1101/2024.03.06.583801

Heydecker M; Shitara A; Chen D; Tran D; Masedunskas A; Tora M; Ebrahim S; Appaduray MA; Galeano Niño JL; Bhardwaj A; Narayan K; Hardeman EC; Gunning PW; Weigert R, 2023, Spatial and Temporal Coordination of Force-generating Actin-based Modules Drives Membrane Remodeling In Vivo., http://dx.doi.org/10.1101/2023.12.04.569944

Mann Z; Lim F; Verma S; Nanavati B; Davies J; Begun J; Hardeman E; Gunning P; Subramanyam D; Yap A; Duszyc K, 2023, Pre-existing tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia, http://dx.doi.org/10.1101/2023.08.31.555652

Kumari R; Ven K; Chastney M; Peränen J; Aaron J; Almeida-Souza L; Kremneva E; Poincloux R; Chew T-L; Gunning P; Ivaska J; Lappalainen P, 2023, Specialized actin nanoscale layers control focal adhesion turnover, http://dx.doi.org/10.1101/2023.02.15.528622

Zhao X; Alibhai D; Walsh T; Tarassova N; Englert M; Birol S; Li Y; Williams C; Neal C; Burkard P; Aitken E; Waller A; Ballester-Beltran J; Gunning P; Hardeman E; Agbani E; Nieswandt B; Hers I; Ghevaert C; Poole A, 2022, Highly efficient platelet generation in lung vasculature reproduced by microfluidics, http://dx.doi.org/10.21203/rs.3.rs-2306404/v1

Redpath GMI; Rae J; Yao Y; Ruan J; Cagigas ML; Whan R; Hardeman EC; Gunning PW; Ananthanarayanan V; Parton RG; Ariotti NA, 2022, Precision super-resolution cryo-correlative light and electron microscopy for rapidin situstructural analyses of optogenetically-positioned organelles, http://dx.doi.org/10.1101/2022.11.22.516823

Kokkinos J; Sharbeen G; Ignacio RM; Pandzic E; Youkhana J; Boyer C; Haghighi K; Gunawarman M; Goldstein D; Gebski V; Pajic M; Pitiyarachchi O; Davis M; Schulstad G; Arkell OSM; Kopecky C; Gonzales-Aloy E; Erkan M; Morton J; Kavallaris M; Gunning P; Hardeman E; Johns A; Gill A; Whan R; Mawson A; Australian Pancreatic Cancer Genome Initiative ; McCarroll J; Phillips P, 2022, βIII-Tubulin is a Brake on Extrinsic Cell-Death in Pancreatic Cancer, http://dx.doi.org/10.1101/2022.09.29.510034

Zhao X; Alibhai D; Walsh T; Tarassova N; Birol S; Williams C; Neil C; Aitken E; Waller A; Ballester-Beltran J; Gunning P; Hardeman E; Agbani E; Hers I; Ghevaert C; Poole A, 2021, Platelet generation from circulating megakaryocytes is triggered in the lung vasculature, http://dx.doi.org/10.1101/2021.11.01.466743

Zhao X; Alibhai D; Walsh T; Tarassova N; Birol S; Williams C; Neil C; Aitken E; Waller A; Ballester-Beltran J; Gunning P; Hardeman E; Agbani E; Hers I; Ghevaert C; Poole A, 2021, Platelet generation from circulating megakaryocytes is triggered in the lung vasculature, http://dx.doi.org/10.21203/rs.3.rs-690639/v1

Rae J; Ferguson C; Ariotti N; Webb R; Cheng H-H; Mead J; Riches J; Hunter DJB; Martel N; Baltos J; Christopoulos A; Bryce N; Cagigas ML; Fonseka S; Hardeman E; Gunning P; Gambin Y; Hall T; Parton R, 2020, APEX-Gold: A genetically-encoded particulate marker for robust 3D electron microscopy, http://dx.doi.org/10.1101/2020.10.06.328831

Abouelezz A; Stefen H; Segerstråle M; Micinski D; Minkeviciene R; Hardeman E; Gunning P; Hoogenraad C; Taira T; Fath T; Hotulainen P, 2019, Tropomyosin Tpm3.1 is required to maintain the structure and function of the axon initial segment, http://dx.doi.org/10.1101/711614

Redpath GMI; Rae J; Yao Y; Ruan J; Cagigas ML; Whan R; Hardeman EC; Gunning PW; Ananthanarayanan V; Parton RG; Ariotti N, Precision Super-Resolution Cryo-Correlative Light and Electron Microscopy for Rapid <i>in situ</i> Structural Analyses of Optogenetically-Positioned Organelles, http://dx.doi.org/10.2139/ssrn.4309027

Abouelezz A; Stefen H; Segerstråle M; Micinski D; Minkeviciene R; Hardeman EC; Gunning PW; Hoogenraad CC; Taira T; Fath T; Hotulainen P, Tropomyosin Tpm3.1 is Required to Maintain the Structure and Function of the Axon Initial Segment, http://dx.doi.org/10.2139/ssrn.3448139

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