By Professor Naresh Kumar

Journal articles

Dobrowolski JC; Somphol K; Santoso M; Duong H; Gardner CR; Kumar N; Black DSC, 2017, 'Methanal extrusion in ipso-substitution reactions of hydroxymethylindoles', Australian Journal of Chemistry, 70, pp. 1188 - 1195, http://dx.doi.org/10.1071/CH17257

Wenholz DS; Zeng M; Ma C; Mielczarek M; Yang X; Bhadbhade M; Black DSC; Lewis PJ; Griffith R; Kumar N, 2017, 'Small molecule inhibitors of bacterial transcription complex formation', Bioorganic and Medicinal Chemistry Letters, 27, pp. 4302 - 4308, http://dx.doi.org/10.1016/j.bmcl.2017.08.036

Nizalapur S; Kimyon O; Yee E; Bhadbhade MM; Manefield M; Willcox M; Black DS; Kumar N, 2017, 'Synthesis and biological evaluation of novel acyclic and cyclic glyoxamide based derivatives as bacterial quorum sensing and biofilm inhibitors', Organic and Biomolecular Chemistry, 15, pp. 5743 - 5755, http://dx.doi.org/10.1039/c7ob01011g

Biswas NN; Yu TT; Kimyon Ö; Nizalapur S; Gardner CR; Manefield M; Griffith R; Black DSC; Kumar N, 2017, 'Synthesis of antimicrobial glucosamides as bacterial quorum sensing mechanism inhibitors', Bioorganic and Medicinal Chemistry, 25, pp. 1183 - 1194, http://dx.doi.org/10.1016/j.bmc.2016.12.024

Kandemir H; Sengul IF; Kumar N; Black DSC, 2017, 'Synthesis of imine and amine-linked macrocycles containing tris-indoles', Australian Journal of Chemistry, 70, pp. 1196 - 1201, http://dx.doi.org/10.1071/CH17264

Yee EMH; Brandl MB; Black DSC; Vittorio O; Kumar N, 2017, 'Synthesis of isoflavene-thiosemicarbazone hybrids and evaluation of their anti-tumor activity', Bioorganic and Medicinal Chemistry Letters, 27, pp. 2454 - 2458, http://dx.doi.org/10.1016/j.bmcl.2017.04.002

Maharajan K; Hallinan JTPD; Sitoula P; Pang YH; Zaw AS; Kumar N, 2017, 'Unusual presentation of osteoblastoma as vertebra plana—a case report and review of literature', Spine Journal, 17, pp. e1 - e5, http://dx.doi.org/10.1016/j.spinee.2016.09.009

Abhishek KS; Chakravarti A; Baveja CP; Kumar N; Siddiqui O; Kumar S, 2017, 'Association of interleukin-2, -4 and -10 with dengue severity.', Indian J Pathol Microbiol, 60, pp. 66 - 69, http://dx.doi.org/10.4103/0377-4929.200027

Kumar N; Ahmed Q; Lee VKM; Zaw AS; Goy R; Wong HK, 2016, 'Are we ready for the use of intraoperative salvaged blood in metastatic spine tumour surgery?', European Spine Journal, 25, pp. 3997 - 4007, http://dx.doi.org/10.1007/s00586-015-4112-x

Kumar N; Zaw AS; Khoo BL; Nandi S; Lai Z; Singh G; Lim CT; Thiery JP, 2016, 'Intraoperative cell salvage in metastatic spine tumour surgery reduces potential for reinfusion of viable cancer cells', European Spine Journal, 25, pp. 4008 - 4015, http://dx.doi.org/10.1007/s00586-016-4478-4

Kumar N; Tan B; Zaw AS; Khine HE; Maharajan K; Lau LL; Rajendran PC; Gopinathan A, 2016, 'The role of preoperative vascular embolization in surgery for metastatic spinal tumours', European Spine Journal, 25, pp. 3962 - 3970, http://dx.doi.org/10.1007/s00586-016-4494-4

Chen R; Cole N; Dutta D; Kumar N; Willcox M; Chen R, 2016, 'Antimicrobial activity of immobilized lactoferrin and lactoferricin', Journal of Biomedical Materials Research Part B: Applied Biomaterials, 105, pp. 2612 - 2617, http://dx.doi.org/10.1002/jbm.b.33804

Dutta D; Vijay AJAY; Kumar NARESH; Willcox M, 2016, 'Melimine-coated Antimicrobial Contact Lenses Reduce Microbial Keratitis in an Animal Model', Investigative Ophthalmology and Visual Science

Kimyon O; Uluturk ZI; Nizalapur S; Lee M; Kutty SK; Beckmann S; Kumar N; Manefield M, 2016, 'N-Acetylglucosamine Inhibits LuxR, LasR and CviR Based Quorum Sensing Regulated Gene Expression Levels', FRONTIERS IN MICROBIOLOGY, 7, http://dx.doi.org/10.3389/fmicb.2016.01313

Kimyon Ö; Ulutürk ZI; Nizalapur S; Lee M; Kutty SK; Beckmann S; Kumar N; Manefield M, 2016, 'N-acetylglucosamine inhibits LuxR, LasR and CviR based quorum sensing regulated gene expression levels', Frontiers in Microbiology, 7, http://dx.doi.org/10.3389/fmicb.2016.01313

Sutton SK; Carter DR; Kim P; Tan O; Arndt GM; Zhang XD; Baell J; Noll BD; Wang S; Kumar N; McArthur GA; Cheung BB; Marshall GM; Arndt G, 2016, 'A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner', Oncotarget, 7, pp. 52166 - 52178, http://dx.doi.org/10.18632/oncotarget.10700

Bingul M; Tan O; Gardner CR; Sutton SK; Arndt GM; Marshall GM; Cheung BB; Kumar N; Black DSC; Arndt G, 2016, 'Synthesis, characterization and anti-cancer activity of hydrazide derivatives incorporating a quinoline moiety', Molecules, 21, pp. 916, http://dx.doi.org/10.3390/molecules21070916

Kandemir H; Sengul IF; Kumar N; Black DSC, 2016, 'Synthesis of a 7-(aminomethyl)indole and related bis-indole derivatives', Arkivoc, 2016, pp. 288 - 295, http://dx.doi.org/10.3998/ark.5550190.p009.587

Kumar N; Zaw AS; Khine HE; Maharajan K; Wai KL; Tan B; Mastura S; Goy R, 2016, 'Blood Loss and Transfusion Requirements in Metastatic Spinal Tumor Surgery: Evaluation of Influencing Factors', Annals of Surgical Oncology, 23, pp. 2079 - 2086, http://dx.doi.org/10.1245/s10434-016-5092-8

Nizalapur S; Ho KKK; Kimyon Ö; Yee E; Berry T; Manefield M; Cranfield CG; Willcox M; Black DSC; Kumar N, 2016, 'Synthesis and biological evaluation of N-naphthoyl-phenylglyoxamide-based small molecular antimicrobial peptide mimics as novel antimicrobial agents and biofilm inhibitors', Organic and Biomolecular Chemistry, 14, pp. 3623 - 3637, http://dx.doi.org/10.1039/c6ob00298f

Chen R; Willcox MDP; Ho KKK; Smyth D; Kumar N, 2016, 'Antimicrobial peptide melimine coating for titanium and its in vivo antibacterial activity in rodent subcutaneous infection models', Biomaterials, 85, pp. 142 - 151, http://dx.doi.org/10.1016/j.biomaterials.2016.01.063

Thach O; Mielczarek M; Ma C; Kutty SK; Yang X; Black DSC; Griffith R; Lewis PJ; Kumar N, 2016, 'From indole to pyrrole, furan, thiophene and pyridine: Search for novel small molecule inhibitors of bacterial transcription initiation complex formation', Bioorganic and Medicinal Chemistry, 24, pp. 1171 - 1182, http://dx.doi.org/10.1016/j.bmc.2016.01.040

Dutta D; Kumar NARESH; Willcox M, 2016, 'Antimicrobial activity of four cationic peptides immobilised to poly-hydroxyethylmethacrylate', Biofouling, http://dx.doi.org/10.1080/08927014.2015.1129533

Biswas NN; Kutty SK; Iskander GM; Mielczarek M; Bhadbhade MM; Gardner CR; Black DSC; Kumar N, 2016, 'Synthesis of brominated novel N-heterocycles: New scaffolds for antimicrobial discovery', Tetrahedron, 72, pp. 539 - 546, http://dx.doi.org/10.1016/j.tet.2015.12.018

Al-Eisawi Z; Stefani C; Jansson PJ; Arvind A; Sharpe PC; Basha MT; Iskander GM; Kumar N; Kovacevic Z; Lane DJR; Sahni S; Bernhardt PV; Richardson DR; Kalinowski DS, 2016, 'Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2-Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe): Lysosomal Membrane Permeabilization', Journal of Medicinal Chemistry, 59, pp. 294 - 312, http://dx.doi.org/10.1021/acs.jmedchem.5b01399

Bingul M; Kumar N; Black DS, 2016, 'Synthesis and reactions of new 2-hydroxymethyldimethoxyindoles', Tetrahedron, 72, pp. 234 - 239, http://dx.doi.org/10.1016/j.tet.2015.11.038

Dobrowolski JC; Katen A; Fraser BH; Bhadbhade M; Black DSC; Kumar N, 2016, 'A general and efficient synthesis of 5,6-dihydrodibenzo[b,h][1,6]naphthyridine derivatives', Tetrahedron Letters, 57, pp. 5442 - 5445, http://dx.doi.org/10.1016/j.tetlet.2016.10.067

Nguyen TK; Selvanayagam R; Ho KKK; Chen R; Kutty SK; Rice SA; Kumar N; Barraud N; Duong HTT; Boyer C, 2016, 'Co-delivery of nitric oxide and antibiotic using polymeric nanoparticles', Chemical Science, 7, pp. 1016 - 1027, http://dx.doi.org/10.1039/c5sc02769a

Nizalapur S; Kimyon Ö; Biswas NN; Gardner CR; Griffith R; Rice SA; Manefield M; Willcox M; Black DSC; Kumar N, 2016, 'Design, synthesis and evaluation of N-aryl-glyoxamide derivatives as structurally novel bacterial quorum sensing inhibitors', Organic and Biomolecular Chemistry, 14, pp. 680 - 693, http://dx.doi.org/10.1039/c5ob01973g

Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Gaus K; Yee E; Kumar N; Duong H; Fleming C; Haber M; Norris M; Boyer C; Kavallaris M, 2016, 'Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth', Oncotarget, 7, pp. 47479 - 47493, http://dx.doi.org/10.18632/oncotarget.10201

Kimyon Ö; Das T; Ibugo AI; Kutty SK; Ho KK; Tebben J; Kumar N; Manefield M, 2016, 'Serratia secondary metabolite prodigiosin inhibits Pseudomonas aeruginosa biofilm development by producing reactive oxygen species that damage biological molecules', Frontiers in Microbiology, 7, http://dx.doi.org/10.3389/fmicb.2016.00972

Tan JJH; Zaw AS; Malhotra R; Wai KL; Tan JYH; Kumar N, 2016, 'Survival prognostication in patients with skeletal metastases from nasopharyngeal carcinoma: An evaluation of the Scandinavian sarcoma group, Katagiri and Bauer scoring systems', Annals of the Academy of Medicine Singapore, 45, pp. 51 - 60

Kandemir H; Sengul IF; Gardner CR; Werry EL; Barron ML; Kassiou M; Kumar N; Black DSC, 2016, 'Synthesis of 7,7′-linked-bis-indoles via 7-tryptamines', Heterocycles, 93, pp. 333 - 346, http://dx.doi.org/10.3987/COM-15-S(T)55

Bansal S; Kumar N; Kochhar AM; Ghai R, 2016, 'Alopecia universalis in a patient with Sheehan's syndrome.', Indian Dermatol Online J, 7, pp. 58 - 59, http://dx.doi.org/10.4103/2229-5178.174322

Biswas NN; Kutty SK; Iskander GM; Mielczarek M; Bhadbhade MM; Gardner CR; Black DS; Kumar N, 2016, 'ChemInform Abstract: Synthesis of Brominated Novel N‐Heterocycles: New Scaffolds for Antimicrobial Discovery.', ChemInform, 47, http://dx.doi.org/10.1002/chin.201620030

Khan NA; Kumar N; Daga MK, 2016, 'Effect of Dietary Supplementation on Body Composition, Pulmonary Function and Health-Related Quality of Life in Patients with Stable COPD.', Tanaffos, 15, pp. 225 - 235, https://www.ncbi.nlm.nih.gov/pubmed/28469679

Khan NA; Daga MK; Ahmad I; Mawari G; Kumar S; Kumar N; Husain SA, 2016, 'Evaluation of BODE index and its relationship with systemic inflammation mediated by proinflammatory biomarkers in patients with COPD.', J Inflamm Res, 9, pp. 187 - 198, http://dx.doi.org/10.2147/JIR.S108783

Taunk A; Kit Ho KK; Iskander G; Willcox MDP; Kumar N, 2016, 'Surface Immobilization of Antibacterial Quorum Sensing Inhibitors by Photochemical Activation', Journal of Biotechnology & Biomaterials, 6, http://dx.doi.org/10.4172/2155-952x.1000238

Kumar N; Tan J; Tan KA; Zaw AS; Tan G; Kumar N; Kumar A, 2016, 'The accuracy of prognostic scoring systems in predicting survival of lung cancer patients with spinal metastases', The Spine Journal, 16, pp. S89 - S90, http://dx.doi.org/10.1016/j.spinee.2016.01.138

Goh WK; Gardner CR; Chandra Sekhar KVG; Biswas NN; Nizalapur S; Rice SA; Willcox M; Black DS; Kumar N, 2015, 'Synthesis, quorum sensing inhibition and docking studies of 1,5-dihydropyrrol-2-ones', Bioorganic and Medicinal Chemistry, 23, pp. 7366 - 7377, http://dx.doi.org/10.1016/j.bmc.2015.10.025

Mielczarek M; Bhadbhade M; Chen R; Kumar N; Black DSC, 2015, 'Bromination of 2,7′-bi-indolyls and quinazolin-7-ones', Tetrahedron, 71, pp. 8925 - 8942, http://dx.doi.org/10.1016/j.tet.2015.09.064

Chen Y; Cass SL; Kutty SK; Yee EMH; Chan DSH; Gardner CR; Vittorio O; Pasquier E; Black DSC; Kumar N, 2015, 'Synthesis, biological evaluation and structure-activity relationship studies of isoflavene based Mannich bases with potent anti-cancer activity', Bioorganic and Medicinal Chemistry Letters, 25, pp. 5377 - 5383, http://dx.doi.org/10.1016/j.bmcl.2015.09.027

Hong KKC; Ball GE; Black DS; Kumar N, 2015, 'The Mosaic of Rottlerin', Journal of Organic Chemistry, 80, pp. 10668 - 10674, http://dx.doi.org/10.1021/acs.joc.5b01827

Singh AK; Kumar N; Sharma P; Singh S, 2015, 'Pleomorphic adenoma involving minor salivary glands of upper lip: A rare phenomenon', Journal of Cancer Research and Therapeutics, 11, pp. 1068 - 1070, http://dx.doi.org/10.4103/0973-1482.148682

Kutty SK; Barraud N; Ho KKK; Iskander GM; Griffith R; Rice SA; Bhadbhade M; Willcox MDP; Black DS; Kumar N, 2015, 'Hybrids of acylated homoserine lactone and nitric oxide donors as inhibitors of quorum sensing and virulence factors in Pseudomonas aeruginosa', Organic and Biomolecular Chemistry, 13, pp. 9850 - 9861, http://dx.doi.org/10.1039/c5ob01373a

Kumar N; Zaw AS; Reyes MR; Malhotra R; Wu PH; Makandura MC; Thambiah J; Liu GKP; Wong HK, 2015, 'Versatility of Percutaneous Pedicular Screw Fixation in Metastatic Spine Tumor Surgery: A Prospective Analysis', Annals of Surgical Oncology, 22, pp. 1604 - 1611, http://dx.doi.org/10.1245/s10434-014-4178-4

Mielczarek M; Thomas RV; Ma C; Kandemir H; Yang X; Bhadbhade M; Black DS; Griffith R; Lewis PJ; Kumar N, 2015, 'Synthesis and biological activity of novel mono-indole and mono-benzofuran inhibitors of bacterial transcription initiation complex formation', Bioorganic and Medicinal Chemistry, 23, pp. 1763 - 1775, http://dx.doi.org/10.1016/j.bmc.2015.02.037

Iskander G; Wood K; Eiffe E; Yee EMH; Black DSC; Kumar N, 2015, 'Ritter reactions of isoflavanols: A facile route to 4-amidoisoflavans', Tetrahedron Letters, 56, pp. 1941 - 1943, http://dx.doi.org/10.1016/j.tetlet.2015.02.072

Das T; Kutty SK; Tavallaie R; Ibugo AI; Panchompoo J; Sehar S; Aldous L; Yeung AWS; Thomas SR; Kumar N; Gooding JJ; Manefield M; Amaye I, 2015, 'Phenazine virulence factor binding to extracellular DNA is important for Pseudomonas aeruginosa biofilm formation', Scientific Reports, 5, pp. 8398, http://dx.doi.org/10.1038/srep08398

Biswas NN; Kutty SK; Barraud N; Iskander GM; Griffith R; Rice SA; Willcox M; Black DS; Kumar N, 2015, 'Indole-based novel small molecules for the modulation of bacterial signalling pathways', Organic and Biomolecular Chemistry, 13, pp. 925 - 937, http://dx.doi.org/10.1039/c4ob02096k

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