By Professor Kristopher Alan Kilian

Book Chapters

LaPointe V; Kilian KA, 2023, 'Cellular signaling', in Tissue Engineering, Elsevier, pp. 109 - 135, http://dx.doi.org/10.1016/B978-0-12-824459-3.00004-4

Romanazzo S; Kilian KA, 2022, 'Geometric Cues for Directing Cell Fate', in Material-based Mechanobiology, The Royal Society of Chemistry, pp. 85 - 109, http://dx.doi.org/10.1039/9781839165375-00085

Romanazzo S; Kilian KA; Roohani I, 2021, 'iPSC bioprinting for musculoskeletal tissue', in Ipscs in Tissue Engineering, pp. 237 - 270, http://dx.doi.org/10.1016/B978-0-12-823809-7.00008-6

Kilian KA, 2015, 'Biomaterials: Incorporating ECM-Derived Molecular Features into Biomaterials', in Mimicking the Extracellular Matrix, The Royal Society of Chemistry, pp. 161 - 194, http://dx.doi.org/10.1039/9781839168956-00161

Journal articles

Huang Y; Li Z; Ranaweera CD; Jayathilaka PB; Islam MS; Ajam A; Silberstein MN; Kilian KA; Kruzic JJ, 2025, 'Stretch activated molecule immobilization in disulfide linked double network hydrogels', Acta Biomaterialia, 198, pp. 174 - 187, http://dx.doi.org/10.1016/j.actbio.2025.04.013

Taief KA; Nemec S; Middleton IA; Kilian KA; Thordarson P, 2025, 'Scrambled RGD Hexameric Peptide Hydrogel Supports Efficient Self-Assembly and Cell Activity', Chemistry A European Journal, 31, http://dx.doi.org/10.1002/chem.202404410

Doshi R; Mohanathas D; Islam MS; Ruan J; Tilley RD; Kilian KA, 2025, 'Biomimetic Hydrogels from Mixed Gellan Gum and Tryptophan Zipper Self-Assembling Peptides', ACS Macro Letters, 14, http://dx.doi.org/10.1021/acsmacrolett.5c00076

Tran HA; Maraldo A; Ho TTP; Thai MT; van Hilst Q; Joukhdar H; Kordanovski M; Sahoo JK; Hartsuk O; Santos M; Wise SG; Kaplan DL; Do TN; Kilian KA; Lim KS; Rnjak-Kovacina J, 2025, 'Probing the Interplay of Protein Self-Assembly and Covalent Bond Formation in Photo-Crosslinked Silk Fibroin Hydrogels', Small, 21, http://dx.doi.org/10.1002/smll.202407923

Hu C; Dief EM; Soliman BG; Romanazzo S; Rana S; Kilian KA; Tilley RD; Gooding JJ, 2025, 'Direct detection of microRNA in liquid biopsies from single cancer spheroids', Chemical Science, 16, pp. 8970 - 8978, http://dx.doi.org/10.1039/d5sc01036e

Islam MS; Molley TG; Jalandhra GK; Fang J; Kruzic JJ; Kilian KA, 2025, 'Magnetoactive Nanotopography on Hydrogels for Stimulated Cell Adhesion and Differentiation', Small Science, 5, http://dx.doi.org/10.1002/smsc.202400468

Putra VDL; Kilian KA; Knothe Tate ML, 2025, 'Stem cell mechanoadaptation. I. Effect of microtubule stabilization and volume changing stresses on cytoskeletal remodeling', APL Bioengineering, 9, http://dx.doi.org/10.1063/5.0231273

Putra VDL; Kilian KA; Knothe Tate ML, 2025, 'Stem cell mechanoadaptation. II. Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling', APL Bioengineering, 9, http://dx.doi.org/10.1063/5.0231287

Li Z; Ranaweera CD; Lin K; Huang Y; Molley TG; Qin L; Kruzic JJ; Kilian KA, 2025, 'Multi-step functionalization of hydrogels through mechano- and photo-responsive linkages', Materials Horizons, 12, pp. 3084 - 3090, http://dx.doi.org/10.1039/d4mh00761a

Tolentino MAK; Du EY; Silvani G; Pandzic E; Kilian KA; Gooding JJ, 2025, 'Decoding Hydrogel Porosity: Advancing the Structural Analysis of Hydrogels for Biomedical Applications', Advanced Healthcare Materials, http://dx.doi.org/10.1002/adhm.202500658

Soliman BG; Tian P; Cui J; Kilian KA; Gooding JJ, 2025, 'Interfacial Stress Regulates Plasticity and Drug Resistance at the Breast Cancer-Host Interface', Advanced Science, http://dx.doi.org/10.1002/advs.202509361

Johnson KK; Koshy P; Kopecky C; Devadason M; Holst J; Kilian KA; Sorrell CC, 2025, 'Theranostic performance of EGFR-targeted ceria-based nanoparticles on EGFR-positive cancers', Journal of Biomaterials Applications, http://dx.doi.org/10.1177/08853282251336556

Tran HA; Maraldo A; Ho TT; Thai MT; van Hilst Q; Joukhdar H; Kordanovski M; Sahoo JK; Hartsuk O; Santos M; Wise SG; Kaplan DL; Do TN; Kilian KA; Lim KS; Rnjak‐Kovacina J, 2025, 'Probing the Interplay of Protein Self‐Assembly and Covalent Bond Formation in Photo‐Crosslinked Silk Fibroin Hydrogels (Small 16/2025)', Small, 21, http://dx.doi.org/10.1002/smll.202570127

Liu Y; Islam MS; Bakker A; Li Z; Ajam A; Kruzic JJ; Kilian KA, 2024, 'Improving the bioactivity and mechanical properties of poly(ethylene glycol)-based hydrogels through a supramolecular support network', Journal of Materials Chemistry B, 13, pp. 1286 - 1295, http://dx.doi.org/10.1039/d4tb02002b

Ireland J; Kilian KA, 2024, 'The importance of matrix in cardiomyogenesis: Defined substrates for maturation and chamber specificity', Matrix Biology Plus, 24, http://dx.doi.org/10.1016/j.mbplus.2024.100160

Soliman BG; Nguyen AK; Gooding JJ; Kilian KA, 2024, 'Advancing Synthetic Hydrogels through Nature-Inspired Materials Chemistry', Advanced Materials, 36, pp. e2404235, http://dx.doi.org/10.1002/adma.202404235

Jalandhra GK; Hung TT; Kilian KA, 2024, 'Laponite Nanoclay-Loaded Microgel Suspensions as Supportive Matrices for Osteogenesis', Advanced Nanobiomed Research, 4, http://dx.doi.org/10.1002/anbr.202400024

Jalandhra GK; Kilian KA, 2024, 'Biofabrication approaches to fabricating gradients and interfaces in osteochondral tissue engineering', Current Opinion in Biomedical Engineering, 31, http://dx.doi.org/10.1016/j.cobme.2024.100544

Ajam A; Huang Y; Islam MS; Kilian KA; Kruzic JJ, 2024, 'Mechanical and biological behavior of double network hydrogels reinforced with alginate versus gellan gum', Journal of the Mechanical Behavior of Biomedical Materials, 157, http://dx.doi.org/10.1016/j.jmbbm.2024.106642

Doshi RB; Vakil D; Molley TG; Islam MS; Kilian KA; Cunningham C; Sidhu KS, 2024, 'Mesenchymal stem cell-secretome laden photopolymerizable hydrogels for wound healing', Journal of Biomedical Materials Research Part A, 112, pp. 1484 - 1493, http://dx.doi.org/10.1002/jbm.a.37697

Karimi F; Farbehi N; Ziaee F; Lau K; Monfared M; Kordanovski M; Joukhdar H; Molly TG; Nordon R; Kilian KA; Stenzel MH; Lim KS; Rnjak-Kovacina J, 2024, 'Photocrosslinked Silk Fibroin Microgel Scaffolds for Biomedical Applications', Advanced Functional Materials, 34, http://dx.doi.org/10.1002/adfm.202313354

Johnson KK; Koshy P; Kopecky C; Devadason M; Biazik J; Zheng X; Jiang Y; Wang X; Liu Y; Holst J; Yang JL; Kilian KA; Sorrell CC, 2024, 'ROS-mediated anticancer effects of EGFR-targeted nanoceria', Journal of Biomedical Materials Research Part A, 112, pp. 754 - 769, http://dx.doi.org/10.1002/jbm.a.37656

Karimi F; Farbehi N; Ziaee F; Lau K; Monfared M; Kordanovski M; Joukhdar H; Molly TG; Nordon R; Kilian KA; Stenzel MH; Lim KS; Rnjak‐Kovacina J, 2024, 'Photocrosslinked Silk Fibroin Microgel Scaffolds for Biomedical Applications (Adv. Funct. Mater. 29/2024)', Advanced Functional Materials, 34, http://dx.doi.org/10.1002/adfm.202470158

Putra VDL; Kilian KA; Knothe Tate ML, 2023, 'Biomechanical, biophysical and biochemical modulators of cytoskeletal remodelling and emergent stem cell lineage commitment', Communications Biology, 6, http://dx.doi.org/10.1038/s42003-022-04320-w

Nguyen AK; Molley TG; Kardia E; Ganda S; Chakraborty S; Wong SL; Ruan J; Yee BE; Mata J; Vijayan A; Kumar N; Tilley RD; Waters SA; Kilian KA, 2023, 'Hierarchical assembly of tryptophan zipper peptides into stress-relaxing bioactive hydrogels', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41907-1

Islam MS; Molley TG; Hung TT; Sathish CI; Putra VDL; Jalandhra GK; Ireland J; Li Y; Yi J; Kruzic JJ; Kilian KA, 2023, 'Magnetic Nanofibrous Hydrogels for Dynamic Control of Stem Cell Differentiation', ACS Applied Materials and Interfaces, 15, pp. 50663 - 50678, http://dx.doi.org/10.1021/acsami.3c07021

Moore MJ; Lam YT; Santos M; Tan RP; Yang N; Hung J; Li Z; Kilian KA; Rnjak-Kovacina J; Pitts JB; Menzel H; Wise SG, 2023, 'Evaluation of the Immune Response to Chitosan-graft-poly(caprolactone) Biopolymer Scaffolds', ACS Biomaterials Science and Engineering, 9, pp. 3320 - 3334, http://dx.doi.org/10.1021/acsbiomaterials.3c00553

Kilian K; Fischbach C; Fong ELS, 2023, 'Engineered Biomaterials for Developing the Next Generation of In Vitro Tumor Models', Advanced Healthcare Materials, 12, http://dx.doi.org/10.1002/adhm.202300411

Liu Y; Nemec S; Kopecky C; Stenzel MH; Kilian KA, 2023, 'Hydrogel Microtumor Arrays to Evaluate Nanotherapeutics', Advanced Healthcare Materials, 12, http://dx.doi.org/10.1002/adhm.202201696

Molley TG; Jiang S; Ong L; Kopecky C; Ranaweera CD; Jalandhra GK; Milton L; Kardia E; Zhou Z; Rnjak-Kovacina J; Waters SA; Toh YC; Kilian KA, 2023, 'Gas-modulating microcapsules for spatiotemporal control of hypoxia', Proceedings of the National Academy of Sciences of the United States of America, 120, pp. e2217557120, http://dx.doi.org/10.1073/pnas.2217557120

Suwannakot P; Nemec S; Peres NG; Du EY; Kilian KA; Gaus K; Kavallaris M; Gooding JJ, 2023, 'Electrostatic Assembly of Multiarm PEG-Based Hydrogels as Extracellular Matrix Mimics: Cell Response in the Presence and Absence of RGD Cell Adhesive Ligands', ACS Biomaterials Science and Engineering, 9, pp. 1362 - 1376, http://dx.doi.org/10.1021/acsbiomaterials.2c01252

Srivastava P; Romanazzo S; Kopecky C; Nemec S; Ireland J; Molley TG; Lin K; Jayathilaka PB; Pandzic E; Yeola A; Chandrakanthan V; Pimanda J; Kilian K, 2023, 'Defined Microenvironments Trigger In Vitro Gastrulation in Human Pluripotent Stem Cells', Advanced Science, 10, http://dx.doi.org/10.1002/advs.202203614

K. Johnson K; Kopecky C; Koshy P; Liu Y; Devadason M; Holst J; A. Kilian K; C. Sorrell C, 2023, 'Theranostic Activity of Ceria-Based Nanoparticles toward Parental and Metastatic Melanoma: 2D vs 3D Models', ACS Biomaterials Science and Engineering, 9, pp. 1053 - 1065, http://dx.doi.org/10.1021/acsbiomaterials.2c01258

Jalandhra GK; Molley TG; Hung TT; Roohani I; Kilian KA, 2023, 'In situ formation of osteochondral interfaces through “bone-ink” printing in tailored microgel suspensions', Acta Biomaterialia, 156, pp. 75 - 87, http://dx.doi.org/10.1016/j.actbio.2022.08.052

Molley TG; Hung TT; Kilian KA, 2022, 'Cell-Laden Gradient Microgel Suspensions for Spatial Control of Differentiation During Biofabrication', Advanced Healthcare Materials, 11, http://dx.doi.org/10.1002/adhm.202201122

Romanazzo S; Kopecky C; Jiang S; Doshi R; Mukund V; Srivastava P; Rnjak-Kovacina J; Kelly K; Kilian KA, 2022, 'Biomaterials directed activation of a cryostable therapeutic secretome in induced pluripotent stem cell derived mesenchymal stromal cells', Journal of Tissue Engineering and Regenerative Medicine, 16, pp. 1008 - 1018, http://dx.doi.org/10.1002/term.3347

Nemec S; Ganda S; Al Taief K; Kopecky C; Kuchel R; Lebhar H; Marquis CP; Thordarson P; Kilian KA, 2022, 'A Tunable Tumor Microenvironment through Recombinant Bacterial Collagen-Hyaluronic Acid Hydrogels', ACS Applied Bio Materials, 5, pp. 4581 - 4588, http://dx.doi.org/10.1021/acsabm.2c00186

Khosravanihaghighi A; Koshy P; Yasir M; Romanazzo S; Lovric V; Kilian KA; Willcox MD; Walsh WR; Sorrell CC, 2022, 'Production of Antibacterial Activity and Bone Cell Proliferation by Surface Engineering of Ga- or Mn-Doped Ceria-Coated Biomedical Titanium Alloy', Advanced Engineering Materials, 24, http://dx.doi.org/10.1002/adem.202200077

Jalandhra G; Romanazzo S; Nemec S; Roohani I; Kilian KA, 2022, 'Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs', Journal of Visualized Experiments, http://dx.doi.org/10.3791/63943-v

Jalandhra G; Romanazzo S; Nemec S; Roohani I; Kilian KA, 2022, 'Ceramic Omnidirectional Bioprinting in Cell-laden Suspensions for the Generation of Bone Analogs', Journal of Visualized Experiments, 2022, http://dx.doi.org/10.3791/63943

Zhang C; Yang B; Biazik J; Webster RF; Xie W; Tang J; Allioux F-M; Abbasi R; Mousavi M; Goldys EM; Killian KA; Chandrawati R; Esrafilzadeh D; Kalantar-Zadeh K, 2022, 'Gallium Nanodroplets are Anti-Inflammatory without Interfering with Iron Homeostasis', ACS Nano, http://dx.doi.org/10.1021/acsnano.1c10981

Huang Y; Jayathilaka PB; Islam MS; Tanaka CB; Silberstein MN; Kilian KA; Kruzic JJ; Baptiston Tanaka C, 2022, 'Structural aspects controlling the mechanical and biological properties of tough, double network hydrogels', Acta Biomaterialia, 138, pp. 301 - 312, http://dx.doi.org/10.1016/j.actbio.2021.10.044

Thavapalachandran S; Le TYL; Romanazzo S; Rashid FN; Ogawa M; Kilian KA; Brown P; Pouliopoulos J; Barry AM; Fahmy P; Kelly K; Kizana E; Chong JJH, 2021, 'Pluripotent stem cell-derived mesenchymal stromal cells improve cardiac function and vascularity after myocardial infarction', Cytotherapy, 23, pp. 1074 - 1084, http://dx.doi.org/10.1016/j.jcyt.2021.07.016

Seidlits SK; Kilian KA, 2021, 'Biomaterials for Personalized Disease Models', Acta Biomaterialia, 132, pp. 1 - 3, http://dx.doi.org/10.1016/j.actbio.2021.08.034

Jayathilaka PB; Molley TG; Huang Y; Islam MS; Buche MR; Silberstein MN; Kruzic JJ; Kilian KA, 2021, 'Force-mediated molecule release from double network hydrogels', Chemical Communications, 57, pp. 8484 - 8487, http://dx.doi.org/10.1039/d1cc02726c

Ma L; Geng J; Kolossov VL; Han Z; Pei Y; Lim SJ; Kilian KA; Smith AM, 2021, 'Antibody self-assembly maximizes cytoplasmic immunostaining accuracy of compact quantum dots', Chemistry of Materials, 33, pp. 4877 - 4889, http://dx.doi.org/10.1021/acs.chemmater.1c00164

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