By Professor Jelena Rnjak-Kovacina

Journal articles

Tran HA; Maraldo A; Ho TTP; Thai MT; van Hilst Q; Joukhdar H; Kordanovski M; Sahoo JK; Hartsuk O; Santos M; Wise SG; Kaplan DL; Do TN; Kilian KA; Lim KS; Rnjak-Kovacina J, 2025, 'Probing the Interplay of Protein Self-Assembly and Covalent Bond Formation in Photo-Crosslinked Silk Fibroin Hydrogels', Small, 21, http://dx.doi.org/10.1002/smll.202407923

Major GS; Joukhdar H; Choi YS; Rnjak-Kovacina J; Wise SG; Ju LA; Cox TR; Xu C; Yeo GC; Young JL; Lim KS, 2025, 'Photochemistry as a tool for dynamic modulation of hydrogel mechanics', Cell Reports Physical Science, 6, http://dx.doi.org/10.1016/j.xcrp.2024.102366

Jiang S; Zhang A; Akhavan B; Whitelock J; Bilek MM; Wise SG; Lord MS; Rnjak-Kovacina J, 2025, 'Biofunctionalization of electrospun silk scaffolds with perlecan for vascular tissue engineering', Biomaterials Science, http://dx.doi.org/10.1039/d5bm00364d

Jalandhra GK; Srethbhakdi L; Davies J; Nguyen CC; Phan PT; Och Z; Ashok A; Lim KS; Phan HP; Do TN; Lovell NH; Rnjak-Kovacina J, 2025, 'Materials Advances in Devices for Heart Disease Interventions', Advanced Materials, http://dx.doi.org/10.1002/adma.202420114

van Hilst QVC; Doan VK; Soliman BG; Li Y; Wang Y; Liu S; Lau K; Joukhdar H; He Q; Hsu CW; Xu C; Rnjak-Kovacina J; Woodfield TBF; Crowley JD; Lim KS, 2025, 'The Potential of Ruthenium(II) Tris-Bidentate Complexes as Multifunctional Photo-Initiators', Macromolecular Materials and Engineering, http://dx.doi.org/10.1002/mame.202400458

Farbehi N; Alinejad-Rokny H; Chtanova T; Rnjak-Kovacina J, 2025, 'Spatial and single-cell transcriptomics unravel the complex interplay between the body and medical implants', Cell Biomaterials, pp. 100099 - 100099, http://dx.doi.org/10.1016/j.celbio.2025.100099

Braxton T; Lim K; Alcala-Orozco C; Joukhdar H; Rnjak-Kovacina J; Iqbal N; Woodfield T; Wood D; Brockett C; Yang XB, 2024, 'Mechanical and Physical Characterization of a Biphasic 3D Printed Silk-Infilled Scaffold for Osteochondral Tissue Engineering', ACS Biomaterials Science and Engineering, 10, pp. 7606 - 7618, http://dx.doi.org/10.1021/acsbiomaterials.4c01865

Santos M; Michael PL; Mitchell TC; Lam YT; Robinson TM; Moore MJ; Tan RP; Rnjak-Kovacina J; Lim KS; Wise SG, 2024, 'On-Demand Bioactivation of Inert Materials With Plasma-Polymerized Nanoparticles', Advanced Materials, 36, http://dx.doi.org/10.1002/adma.202311313

Jiang S; Yang N; Tan RP; Moh ESX; Fu L; Packer NH; Whitelock JM; Wise SG; Rnjak-Kovacina J; Lord MS, 2024, 'Tuning Recombinant Perlecan Domain V to Regulate Angiogenic Growth Factors and Enhance Endothelialization of Electrospun Silk Vascular Grafts', Advanced Healthcare Materials, 13, http://dx.doi.org/10.1002/adhm.202400855

Karimi F; Farbehi N; Ziaee F; Lau K; Monfared M; Kordanovski M; Joukhdar H; Molly TG; Nordon R; Kilian KA; Stenzel MH; Lim KS; Rnjak-Kovacina J, 2024, 'Photocrosslinked Silk Fibroin Microgel Scaffolds for Biomedical Applications', Advanced Functional Materials, 34, http://dx.doi.org/10.1002/adfm.202313354

Vuong TNAM; Bartolf-Kopp M; Andelovic K; Jungst T; Farbehi N; Wise SG; Hayward C; Stevens MC; Rnjak-Kovacina J, 2024, 'Integrating Computational and Biological Hemodynamic Approaches to Improve Modeling of Atherosclerotic Arteries', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202307627

Major GS; Doan VK; Longoni A; Bilek MMM; Wise SG; Rnjak-Kovacina J; Yeo GC; Lim KS, 2024, 'Mapping the microcarrier design pathway to modernise clinical mesenchymal stromal cell expansion', Trends in Biotechnology, 42, pp. 859 - 876, http://dx.doi.org/10.1016/j.tibtech.2024.01.001

Vettori L; Tran HA; Mahmodi H; Filipe EC; Wyllie K; Liu Chung Ming C; Cox TR; Tipper J; Kabakova IV; Rnjak-Kovacina J; Gentile C, 2024, 'Silk fibroin increases the elasticity of alginate-gelatin hydrogels and regulates cardiac cell contractile function in cardiac bioinks', Biofabrication, 16, http://dx.doi.org/10.1088/1758-5090/ad4f1b

Maraldo A; Rnjak-Kovacina J; Marquis C, 2024, 'Tyrosine – a structural glue for hierarchical protein assembly', Trends in Biochemical Sciences, 49, pp. 633 - 648, http://dx.doi.org/10.1016/j.tibs.2024.03.014

Longoni A; Arnold S; Major GS; Jiang A; Wise LM; Hooper GJ; Kieser D; Woodfield TBF; Rnjak-Kovacina J; Lim KS, 2024, 'GELATIN AND VEGF INCORPORATION IN PVA-TYRAMINE HYDROGELS AS A STRATEGY TO ENHANCE VASCULAR INFILTRATION AND TREAT AVASCULAR NECROSIS', Orthopaedic Proceedings, 106-B, pp. 15 - 15, http://dx.doi.org/10.1302/1358-992x.2024.8.015

Ho TTP; Tran HA; Doan VK; Maitz J; Li Z; Wise SG; Lim KS; Rnjak-Kovacina J, 2024, 'Natural Polymer-Based Materials for Wound Healing Applications', Advanced Nanobiomed Research, 4, http://dx.doi.org/10.1002/anbr.202300131

Major G; Ahn M; Cho WW; Santos M; Wise J; Phillips E; Wise SG; Jang J; Rnjak-Kovacina J; Woodfield T; Lim KS, 2024, 'Programming temporal stiffness cues within extracellular matrix hydrogels for modelling cancer niches', Materials Today Bio, 25, http://dx.doi.org/10.1016/j.mtbio.2024.101004

Jiang S; Wise SG; Kovacic JC; Rnjak-Kovacina J; Lord MS, 2024, 'Biomaterials containing extracellular matrix molecules as biomimetic next-generation vascular grafts', Trends in Biotechnology, 42, pp. 369 - 381, http://dx.doi.org/10.1016/j.tibtech.2023.09.009

Ho MH; van Hilst Q; Cui X; Ramaswamy Y; Woodfield T; Rnjak-Kovacina J; Wise SG; Lim KS, 2024, 'From Adhesion to Detachment: Strategies to Design Tissue-Adhesive Hydrogels', Advanced Nanobiomed Research, 4, http://dx.doi.org/10.1002/anbr.202300090

Ho MH; van Hilst Q; Cui X; Ramaswamy Y; Woodfield T; Rnjak-Kovacina J; Wise SG; Lim KS, 2024, 'From Adhesion to Detachment: Strategies to Design Tissue-Adhesive Hydrogels', ADVANCED NANOBIOMED RESEARCH, 4, http://dx.doi.org/10.1002/anbr.202470021

Longoni A; Major GS; Jiang S; Farrugia BL; Kieser DC; Woodfield TBF; Rnjak-Kovacina J; Lim KS, 2023, 'Pristine gelatin incorporation as a strategy to enhance the biofunctionality of poly(vinyl alcohol)-based hydrogels for tissue engineering applications', Biomaterials Science, 12, pp. 134 - 150, http://dx.doi.org/10.1039/d3bm01172k

Kim HN; Elgundi Z; Lin X; Fu L; Tang F; Moh ESX; Jung MS; Chandrasekar K; Bartlett-Tomasetig F; Foster C; Packer NH; Whitelock JM; Rnjak-Kovacina J; Lord MS, 2023, 'Engineered short forms of perlecan enhance angiogenesis by potentiating growth factor signalling', Journal of Controlled Release, 362, pp. 184 - 196, http://dx.doi.org/10.1016/j.jconrel.2023.08.052

Grant AJ; Yang N; Moore MJ; Lam YT; Michael PL; Chan AHP; Santos M; Rnjak-Kovacina J; Tan RP; Wise SG, 2023, 'Selective NLRP3 Inflammasome Inhibitor MCC950 Suppresses Inflammation and Facilitates Healing in Vascular Materials', Advanced Science, 10, http://dx.doi.org/10.1002/advs.202300521

Moore MJ; Lam YT; Santos M; Tan RP; Yang N; Hung J; Li Z; Kilian KA; Rnjak-Kovacina J; Pitts JB; Menzel H; Wise SG, 2023, 'Evaluation of the Immune Response to Chitosan-graft-poly(caprolactone) Biopolymer Scaffolds', ACS Biomaterials Science and Engineering, 9, pp. 3320 - 3334, http://dx.doi.org/10.1021/acsbiomaterials.3c00553

Lau K; Fu L; Zhang A; Akhavan B; Whitelock J; Bilek MM; Lord MS; Rnjak-Kovacina J, 2023, 'Recombinant perlecan domain V covalently immobilized on silk biomaterials via plasma immersion ion implantation supports the formation of functional endothelium', Journal of Biomedical Materials Research Part A, 111, pp. 825 - 839, http://dx.doi.org/10.1002/jbm.a.37525

Tran HA; Hoang TT; Maraldo A; Do TN; Kaplan DL; Lim KS; Rnjak-Kovacina J, 2023, 'Emerging silk fibroin materials and their applications: New functionality arising from innovations in silk crosslinking', Materials Today, 65, pp. 244 - 259, http://dx.doi.org/10.1016/j.mattod.2023.03.027

Thai MT; Phan PT; Tran HA; Nguyen CC; Hoang TT; Davies J; Rnjak-Kovacina J; Phan HP; Lovell NH; Do TN, 2023, 'Advanced Soft Robotic System for In Situ 3D Bioprinting and Endoscopic Surgery', Advanced Science, 10, pp. 2205656, http://dx.doi.org/10.1002/advs.202205656

Joukhdar H; Och Z; Tran H; Heu C; Vasquez GM; Sultana N; Stevens M; Dokos S; Lim KS; Lord MS; Rnjak-Kovacina J, 2023, 'Imparting Multi-Scalar Architectural Control into Silk Materials Using a Simple Multi-Functional Ice-Templating Fabrication Platform', Advanced Materials Technologies, 8, http://dx.doi.org/10.1002/admt.202201642

Molley TG; Jiang S; Ong L; Kopecky C; Ranaweera CD; Jalandhra GK; Milton L; Kardia E; Zhou Z; Rnjak-Kovacina J; Waters SA; Toh YC; Kilian KA, 2023, 'Gas-modulating microcapsules for spatiotemporal control of hypoxia', Proceedings of the National Academy of Sciences of the United States of America, 120, pp. e2217557120, http://dx.doi.org/10.1073/pnas.2217557120

Soliman BG; Longoni A; Wang M; Li W; Bernal PN; Cianciosi A; Lindberg GCJ; Malda J; Groll J; Jungst T; Levato R; Rnjak-Kovacina J; Woodfield TBF; Zhang YS; Lim KS, 2023, 'Programming Delayed Dissolution Into Sacrificial Bioinks For Dynamic Temporal Control of Architecture within 3D-Bioprinted Constructs', Advanced Functional Materials, 33, http://dx.doi.org/10.1002/adfm.202210521

Soliman BG; Longoni A; Wang M; Li W; Bernal PN; Cianciosi A; Lindberg GCJ; Malda J; Groll J; Jungst T; Levato R; Rnjak‐Kovacina J; Woodfield TBF; Zhang YS; Lim KS, 2023, 'Programming Delayed Dissolution Into Sacrificial Bioinks For Dynamic Temporal Control of Architecture within 3D‐Bioprinted Constructs (Adv. Funct. Mater. 8/2023)', Advanced Functional Materials, 33, http://dx.doi.org/10.1002/adfm.202370047

Rnjak-Kovacina J; Choi YS; Lim KS, 2022, 'Biofabrication Applications', Advanced Healthcare Materials, 11, http://dx.doi.org/10.1002/adhm.202202934

Amin ML; Deng K; Tran HA; Singh R; Rnjak-Kovacina J; Thorn P, 2022, 'Glucose-Dependent Insulin Secretion from β Cell Spheroids Is Enhanced by Embedding into Softer Alginate Hydrogels Functionalised with RGD Peptide', Bioengineering, 9, http://dx.doi.org/10.3390/bioengineering9120722

Romanazzo S; Kopecky C; Jiang S; Doshi R; Mukund V; Srivastava P; Rnjak-Kovacina J; Kelly K; Kilian KA, 2022, 'Biomaterials directed activation of a cryostable therapeutic secretome in induced pluripotent stem cell derived mesenchymal stromal cells', Journal of Tissue Engineering and Regenerative Medicine, 16, pp. 1008 - 1018, http://dx.doi.org/10.1002/term.3347

Karimi F; Lau K; Kim HN; Och Z; Lim KS; Whitelock J; Lord M; Rnjak-Kovacina J, 2022, 'Surface Biofunctionalization of Silk Biomaterials Using Dityrosine Cross-Linking', ACS Applied Materials and Interfaces, 14, pp. 31551 - 31566, http://dx.doi.org/10.1021/acsami.2c03345

Moore MJ; Tan RP; Yang N; Rnjak-Kovacina J; Wise SG, 2022, 'Bioengineering artificial blood vessels from natural materials', Trends in Biotechnology, 40, pp. 693 - 707, http://dx.doi.org/10.1016/j.tibtech.2021.11.003

Man K; Joukhdar H; Manz XD; Brunet MY; Jiang LH; Rnjak-Kovacina J; Yang XB, 2022, 'Bone tissue engineering using 3D silk scaffolds and human dental pulp stromal cells epigenetic reprogrammed with the selective histone deacetylase inhibitor MI192', Cell and Tissue Research, 388, pp. 565 - 581, http://dx.doi.org/10.1007/s00441-022-03613-0

Lau K; Heu C; Moore MJ; Zhang A; Akhavan B; Wise SG; Bilek MMM; Lord MS; Rnjak-Kovacina J, 2022, 'Effect of plasma ion immersion implantation on physiochemical and biological properties of silk towards creating a versatile biomaterial platform', Materials Today Advances, 13, http://dx.doi.org/10.1016/j.mtadv.2022.100212

Soliman BG; Major GS; Atienza-Roca P; Murphy CA; Longoni A; Alcala-Orozco CR; Rnjak-Kovacina J; Gawlitta D; Woodfield TBF; Lim KS, 2022, 'Development and Characterization of Gelatin-Norbornene Bioink to Understand the Interplay between Physical Architecture and Micro-Capillary Formation in Biofabricated Vascularized Constructs', Advanced Healthcare Materials, 11, http://dx.doi.org/10.1002/adhm.202101873

Soliman BG; Major GS; Atienza‐Roca P; Murphy CA; Longoni A; Alcala‐Orozco CR; Rnjak‐Kovacina J; Gawlitta D; Woodfield TBF; Lim KS, 2022, 'Development and Characterization of Gelatin‐Norbornene Bioink to Understand the Interplay between Physical Architecture and Micro‐Capillary Formation in Biofabricated Vascularized Constructs (Adv. Healthcare Mater. 2/2022)', Advanced Healthcare Materials, 11, http://dx.doi.org/10.1002/adhm.202270007

Lam YT; Tan RP; Michael PL; Lau K; Yang N; Rnjak-Kovacina J; Wise SG, 2021, 'Bioengineering silk into blood vessels', Biochemical Society Transactions, 49, pp. 2271 - 2286, http://dx.doi.org/10.1042/BST20210359

Polonchuk L; Surija L; Lee MH; Sharma P; Ming CLC; Richter F; Ben-Sefer E; Rad MA; Sarmast HMS; Al Shamery W; Tran HA; Vettori L; Haeusermann F; Filipe EC; Rnjak-Kovacina J; Cox T; Tipper J; Kabakova I; Gentile C, 2021, 'Towards engineering heart tissues from bioprinted cardiac spheroids', Biofabrication, 13, http://dx.doi.org/10.1088/1758-5090/ac14ca

Lau K; Waterhouse A; Akhavan B; Gao L; Kim HN; Tang F; Whitelock JM; Bilek MM; Lord MS; Rnjak-Kovacina J, 2021, 'Biomimetic silk biomaterials: Perlecan-functionalized silk fibroin for use in blood-contacting devices', Acta Biomaterialia, 132, pp. 162 - 175, http://dx.doi.org/10.1016/j.actbio.2021.02.014

Monfared M; Mawad D; Rnjak-Kovacina J; Stenzel MH, 2021, '3D bioprinting of dual-crosslinked nanocellulose hydrogels for tissue engineering applications', Journal of Materials Chemistry B, 9, pp. 6163 - 6175, http://dx.doi.org/10.1039/d1tb00624j

Joukhdar H; Seifert A; Jüngst T; Groll J; Lord MS; Rnjak-Kovacina J, 2021, 'Ice Templating Soft Matter: Fundamental Principles and Fabrication Approaches to Tailor Pore Structure and Morphology and Their Biomedical Applications', Advanced Materials, 33, http://dx.doi.org/10.1002/adma.202100091

Yang N; Moore MJ; Michael PL; Santos M; Lam YT; Bao S; Ng MKC; Rnjak-Kovacina J; Tan RP; Wise SG, 2021, 'Silk Fibroin Scaffold Architecture Regulates Inflammatory Responses and Engraftment of Bone Marrow-Mononuclear Cells', Advanced Healthcare Materials, 10, http://dx.doi.org/10.1002/adhm.202100615

Longoni A; Li J; Lindberg GCJ; Rnjak-Kovacina J; Wise LM; Hooper GJ; Woodfield TBF; Kieser DC; Lim KS, 2021, 'Strategies for inclusion of growth factors into 3D printed bone grafts', Essays in Biochemistry, 65, pp. 569 - 585, http://dx.doi.org/10.1042/EBC20200130

Chandrasekar K; Farrugia BL; Johnson L; Marks D; Irving D; Elgundi Z; Lau K; Kim HN; Rnjak-Kovacina J; Bilek MM; Whitelock JM; Lord MS, 2021, 'Effect of Recombinant Human Perlecan Domain V Tethering Method on Protein Orientation and Blood Contacting Activity on Polyvinyl Chloride', Advanced Healthcare Materials, 10, http://dx.doi.org/10.1002/adhm.202100388

Yan Y; Travaglini L; Lau K; Rnjak-Kovacina J; Ta D; Eslami M; Yang S; Lauto A; Officer DL; Mawad D, 2021, 'Impact of Sterilization on a Conjugated Polymer-Based Bioelectronic Patch', ACS Applied Polymer Materials, 3, pp. 2541 - 2552, http://dx.doi.org/10.1021/acsapm.1c00131

Baptista M; Joukhdar H; Alcala-Orozco CR; Lau K; Jiang S; Cui X; He S; Tang F; Heu C; Woodfield TBF; Lim KS; Rnjak-Kovacina J, 2020, 'Silk fibroin photo-lyogels containing microchannels as a biomaterial platform for: In situ tissue engineering', Biomaterials Science, 8, pp. 7093 - 7105, http://dx.doi.org/10.1039/d0bm01010c

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