By Professor Herbert Herzog

Journal articles

Balasubramaniam A; Mullins D; Lin S; Zhai W; Tao Z; Dhawan V; Guzzi M; Knittel J; Slack K; Herzog H; Parker E, 2006, 'Neuropeptide Y (NPY) Y-4 receptor selective agonists based on NPY(32-36): Development of an anorectic Y-4 receptor selective agonist with picomolar affinity', Journal of Medicinal Chemistry, 49, pp. 2661 - 2665

Tu B; Jiao Y; Herzog H; Nadler JV, 2006, 'Neuropeptide Y regulates recurrent mossy fiber synaptic transmission less effectively in mice than in rats: correlation with Y2 receptor plasticity', Neuroscience, 143, pp. 1085 - 1094

Boey D; Lin SC; Karl T; Baldock P; Lee NJ; Enriquez R; Couzens M; Slack K; Dallmann R; Sainsbury A; Herzog H, 2006, 'Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity', Diabetologia, 49, pp. 1360 - 1370

Wultsch T; Painsipp E; Donner S; Sperk G; Herzog H; Peskar B; Holzer P, 2006, 'Selective increase of dark phase water intake in neuropeptide-Y Y2 and Y4 receptor knockout mice', Behavioural Brain Research, 168, pp. 255 - 260

Doyle K; Hort Y; Shine J; Herzog H, 2006, 'The role of neuropeptide Y in the neuroproliferation of adult olfactory stem cells', CYTOMETRY PART A, 69A, pp. 407 - 408

Sainsbury A; Bergen H; Boey D; Bamming D; Cooney GJ; Lin S; Couzens M; Stroth N; Lee NJ; Lindner D; Singewald N; Karl T; Dury L; Enriquez R; Slack K; Sperk G; Herzog H, 2006, 'Y2Y4 receptor double knockout protects against obesity due to a high-fat diet or Y1 receptor deficiency in mice', Diabetes, 55, pp. 19 - 26

Molero JC; Jensen TE; Withers PC; Couzens M; Herzog H; Thien CBF; Langdon WY; Walder K; Murphy MA; Bowtell DDL; Hardeman E; Ghoddusi M; James DE; Cooney GJ, 2005, 'Erratum: c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action (Journal of Clinical Investigation (2004) 114 (1326-1333) (doi:10.1172/JCI200421480))', Journal of Clinical Investigation, 115, pp. 476, http://dx.doi.org/10.1172/JCI200521480C1

Wheway JE; MacKay CR; Newton R; Sainsbury A; Boey D; Herzog H; Mackay F, 2005, 'A fundamental bimodal role for neuropeptide Y1 receptor in the immune system', Journal of Experimental Medicine, 202, pp. 1527 - 1538

Baldock P; Allison SJ; Sainsbury A; Enriquez R; Herzog H; Gardiner EM; Eisman JA, 2005, 'Central regulation of cortical bone: Opposing effects of Y2 receptor and leptin pathways', Journal of Bone and Mineral Research, 20, pp. S413 - S414

Lin S; Boey D; Couzens M; Lee NALNA; Sainsbury A; Herzog H, 2005, 'Compensatory changes in [125I]-PYY binding in Y receptor knockout mice suggest the potential existence of further Y receptor(s)', Neuropeptides, 39, pp. 21 - 28, http://www.sciencedirect.com/science/article/B6WNR-4DVW1TJ-1/2/d0dbc6cc22317a81a0a2ba01096a4767

Painsipp E; Wultsch T; Sperk G; Herzog H; Holzer R, 2005, 'Differential changes in stress-induced hyperthermia, depression-like behaviour and defaecation by NPY-Y2 and-Y4 receptor gene knockout', Behavioural Pharmacology, 16, pp. S90 - S90

Wultsch T; Painsipp E; Thoeringer C; Herzog H; Sperk G; Holzer P, 2005, 'Endogenous neuropeptide Y depresses the afferent signaling of gastric acid challenge to the mouse brainstem via neuropeptide Y type Y2 and Y4 receptors', Neuroscience, 136, pp. 1097 - 1107

Molero JC; Jensen T; Withers P; Couzens M; Herzog H; Thien C; Langdon WY; Walder K; Murphy M; Bowtell D; Hardeman E; Ghoddusi M; James DE; Cooney GJ, 2005, 'Erratum: c-Cbl-deficient mice have reduced adiposity, higher energy expenditure,and improved peripheral insulin action (vol 114, pg 1326, 2004)', Journal of Clinical Investigation, 115, pp. 476 - 476, http://dx.doi.org/10.1172/JCI21480C1

Baldock P; Sainsbury A; Allison SJ; Lin E; Couzens M; Boey D; Enriquez R; During M; Herzog H; Gardiner EM, 2005, 'Hypothalamic control of bone formation: Distinct actions of leptin and Y2 receptor pathways', Journal of Bone and Mineral Research, 20, pp. 1851 - 1857

Howell O; Doyle KL; Goodman J; Scharfman H; Herzog H; Pringle A; Beck-Sickinger A; Gray W, 2005, 'Neuropeptide Y stimulates neuronal precursor proliferation in the post-natal and adult dentate gyrus', Journal of Neurochemistry, 93, pp. 560 - 570

Brumovsky P; Stanic D; Shuster S; Herzog H; Villar M; Hokfelt T, 2005, 'Neuropeptide Y2 receptor protein is present in peptidergic and nonpeptidergic primary sensory neurons of the mouse', Journal of Comparative Neurology, 489, pp. 328 - 348

Lang R; Berger A; Santic R; Geisberger R; Hermann A; Herzog H; Kofler B, 2005, 'Pharmacological and functional characterization of galanin-like peptide fragments as potent galanin receptor agonists', Neuropeptides, 39, pp. 179 - 184

Wultsch T; Painsipp E; Peskar B; Sperk G; Herzog H; Holzer R, 2005, 'Selective increase of dark-phase water intake in NPY-Y2 and-Y4 receptor knockout mice', Behavioural Pharmacology, 16, pp. S68 - S68

El Bahh B; Balosso S; Hamilton T; Herzog H; Beck-Sickinger A; Sperk G; Gehlert D; Vezzani A; Colmers W, 2005, 'The anti-epileptic actions of neuropeptide Y in the hippocampus are mediated by Y-2 and not Y-5 receptors', European Journal of Neuroscience, 22, pp. 1417 - 1430

Wittmann W; Loacker S; Kapeller I; Herzog H; Schwarzer C, 2005, 'Y1-receptors regulate the expression of Y2-receptors in distinct mouse forebrain areas', Neuroscience, 136, pp. 241 - 250

Baldock P; Allison SJ; Sainsbury A; Enriquez R; Herzog H; Eisman JA; Gardiner EM, 2005, 'Y2 receptors and the central regulation of cortical bone: Reciprocal activity to leptin', Bone, 36, pp. S142 - S142

Batterham RL; Cowley MA; Small CJ; Herzog H; Cohen MA; Dakin CL; Wren AM; Brynes AE; Low MJ; Ghatei MA; Cone RD; Bloom SR, 2004, 'Physiology: Does gut hormone PYY3–36 decrease food intake in rodents?', Nature, 430, http://dx.doi.org/10.1038/nature02666a

Wheway JE; Herzog H; Mackay F, 2004, 'An important role for neuropeptide Y and receptors in regulating adaptive immune responses', Journal of Neuroimmunology, 154, pp. 126 - 126

Molero JC; Jensen T; Withers P; Couzens M; Herzog H; Thien C; Langdon WY; Walder K; Murphy M, 2004, 'c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action', Journal of Clinical Investigation, 114, pp. 1326 - 1333, http://www.sciencedirect.com/science/article/B6WVB-4DPKVPD-2S2/2/3e8b10f3525abc50c3927019a8a862ab

Redrobe J; Dumont Y; Herzog H; Quirion R, 2004, 'Characterization of neuropeptide Y,Y-2 receptor knockout mice in twoanimal models of learning and memory processing', Journal of Molecular Neuroscience, 22, pp. 159 - 166

Painsipp E; Wultsch T; Hetzenauer F; Singewald N; Sperk G; Herzog H; Holzer P, 2004, 'Differential changes in homecage activity, baseline temperature andstress-induced hyperthermia in neuropeptide-YY2 and Y-4 receptorknockout mice', Pharmacology, 72, pp. 136 - 136

Allison SJ; Baldock P; Sainsbury A; Enriquez R; Couzens M; Herzog H; Gardiner EM, 2004, 'Distinct Y-receptor effects on leptin antiosteogenic and adipogenic pathways', Journal of Bone and Mineral Research, 19, pp. S27 - S27

Batterham RL; Cowley MA; Small CJ; Herzog H; Cohen MA; Dakin CL; Wren AM; Brynes AE; Low MJ; Ghatei MA; Cone RD; Bloom SR, 2004, 'Does gut hormone PYY3–36 decrease food intake in rodents? (reply)', Nature, 430, pp. 3 - 4, http://dx.doi.org/10.1038/nature02666

Lin S; Boey D; Herzog H, 2004, 'NPY and Y receptors: lessons from transgenic and knockout models', Neuropeptides, 38, pp. 189 - 200, http://www.sciencedirect.com/science/article/B6WNR-4CS4M5B-2/2/709f0f5c8dc06f0a0cd386e61432678a

Baldock P; Allison SJ; Sainsbury A; Lin DE; Enriquez R; During M; Herzog H; Gardiner EM, 2004, 'Pleiotropic responses to hypothalamic neuropeptide Y1 receptor deletion are associated with a high bone mass phenotype', Journal of Bone and Mineral Research, 19, pp. S32 - S32

Herzog H, 2003, 'Neuropeptide Y and energy homeostasis: Insights from Y receptor knockout models', European Journal of Pharmacology, 480, pp. 21 - 29, http://dx.doi.org/10.1016/j.ejphar.2003.08.089

Chu DQ; Cox HM; Costa SKP; Herzog H; Brain SD, 2003, 'The ability of neuropeptide Y to mediate responses in the murine cutaneous microvasculature: An analysis of the contribution of Y 1 and Y 2 receptors', British Journal of Pharmacology, 140, pp. 422 - 430, http://dx.doi.org/10.1038/sj.bjp.0705452

Howell OW; Scharfman HE; Herzog H; Sundstrom LE; Beck-Sickinger A; Gray WP, 2003, 'Neuropeptide Y is neuroproliferative for post-natal hippocampal precursor cells', Journal of Neurochemistry, 86, pp. 646 - 659, http://dx.doi.org/10.1046/j.1471-4159.2003.01895.x

Sainsbury A; Baldock PA; Schwarzer C; Ueno N; Enriquez RF; Couzens M; Inui A; Herzog H; Gardiner EM, 2003, 'Synergistic effects of Y2 and Y4 receptors on adiposity and bone mass revealed in double knockout mice', Molecular and Cellular Biology, 23, pp. 5225 - 5233, http://dx.doi.org/10.1128/MCB.23.15.5225-5233.2003

Tschenett A; Singewald N; Carli M; Balducci C; Salchner P; Vezzani A; Herzog H; Sperk G, 2003, 'Reduced anxiety and improved stress coping ability in mice lacking NPY-Y2 receptors', European Journal of Neuroscience, 18, pp. 143 - 148, http://dx.doi.org/10.1046/j.1460-9568.2003.02725.x

Hyland NP; Sjöberg F; Tough IR; Herzog H; Cox HM, 2003, 'Functional consequences of neuropeptide Y Y 2 receptor knockout and Y 2 antagonism in mouse and human colonic tissues', British Journal of Pharmacology, 139, pp. 863 - 871, http://dx.doi.org/10.1038/sj.bjp.0705298

Redrobe JP; Dumont Y; Herzog H; Quirion R, 2003, 'Neuropeptide Y (NPY) Y2 receptors mediate behaviour in two animal models of anxiety: Evidence from Y2 receptor knockout mice', Behavioural Brain Research, 141, pp. 251 - 255, http://dx.doi.org/10.1016/S0166-4328(02)00374-1

Denton CP; Evans LA; Shiwen XU; Abraham DJ; De Crombrugghe B; Black CM, 2003, 'A Novel Transgenic Mouse Model for Systemic Sclerosis with Balanced Upregulation of Tgfβ Signalling Pathways', Clinical Science, 104, pp. 1P - 1P, http://dx.doi.org/10.1042/cs104001pa

Baldock P; Sainsbury A; Enriquez R; Couzens M; Herzog H; Gardiner EM, 2003, 'Gender dependent neuroregulation of bone mass: Evidence from theneuropeptide YY2/Y4 double knockout mouse', Journal of Bone and Mineral Research, 18, pp. S27 - S27

Sainsbury A; Schwarzer C; Couzens M; Herzog H, 2002, 'Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice', Diabetes, 51, pp. 3420 - 3427, http://dx.doi.org/10.2337/diabetes.51.12.3420

Herzog H, 2002, 'Hypothalamic Y2 receptors: Central coordination of energy homeostasis and bone mass regulation', Drug News and Perspectives, 15, pp. 506 - 510, http://dx.doi.org/10.1358/dnp.2002.15.8.740226

Blumenthal JB; Andersen RE; Mitchell BD; Seibert MJ; Yang H; Herzog H; Beamer BA; Franckowiak SC; Walston JD, 2002, 'Novel neuropeptide Y1 and Y5 receptor gene variants: Associations with serum triglyceride and high-density lipoprotein cholesterol levels', Clinical Genetics, 62, pp. 196 - 202, http://dx.doi.org/10.1034/j.1399-0004.2002.620302.x

Batterham RL; Cowley MA; Small CJ; Herzog H; Cohen MA; Dakin CL; Wren AM; Brynes AE; Low MJ; Ghatei MA; Cone RD; Bloom SR, 2002, 'Gut hormone PYY3-36 physiologically inhibits food intake', Nature, 418, pp. 650 - 654, http://dx.doi.org/10.1038/nature00887

Sainsbury A; Schwarzer C; Couzens M; Fetissov S; Furtinger S; Jenkins A; Cox HM; Sperk G; Hökfelt T; Herzog H, 2002, 'Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice', Proceedings of the National Academy of Sciences of the United States of America, 99, pp. 8938 - 8943, http://dx.doi.org/10.1073/pnas.132043299

Kopp J; Xu ZQ; Zhang X; Pedrazzini T; Herzog H; Kresse A; Wong H; Walsh JH; Hökfelt T, 2002, 'Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization', Neuroscience, 111, pp. 443 - 532, http://dx.doi.org/10.1016/S0306-4522(01)00463-8

Sainsbury A; Schwarzer C; Couzens M; Jenkins A; Oakes SR; Ormandy CJ; Herzog H, 2002, 'Y4 receptor knockout rescues fertility in ob/ob mice', Genes and Development, 16, pp. 1077 - 1088, http://dx.doi.org/10.1101/gad.979102

Hyland NP; Herzog H; Cox HM, 2002, 'Decreased sensitivity to pancreatic polypeptide in colonic mucosa from Y-2 receptor knockout mice', BRITISH JOURNAL OF PHARMACOLOGY, 135, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000174345200043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tough IR; De Souza RJ; Herzog H; Cox HM, 2002, 'Pancreatic polypeptide responses in colonic mucosal and smooth muscle preparations from wild type and Y-4 receptor knockout mice', BRITISH JOURNAL OF PHARMACOLOGY, 135, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000174345200044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sainsbury A; Cooney GJ; Herzog H, 2002, 'Hypothalamic regulation of energy homeostasis', Best Practice and Research Clinical Endocrinology and Metabolism, 16, pp. 623 - 637, http://dx.doi.org/10.1053/beem.2002.0230

Baldock PA; Sainsbury A; Couzens M; Enriquez RF; Thomas GP; Gardiner EM; Herzog H, 2002, 'Hypothalamic Y2 receptors regulate bone formation', Journal of Clinical Investigation, 109, pp. 915 - 921, http://dx.doi.org/10.1172/JCI0214588

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