By Professor David Thomas

Journal articles

Leung DH; Heltshe SL; Borowitz D; Gelfond D; Kloster M; Heubi JE; Stalvey M; Ramsey BW; Stecenko A; Schechter M; Hunter E; Hoover W; Hathorne H; Brand K; Filbrun A; Linn M; Borowitz D; Caci N; McWilliams B; Brazil I; Bushman M; McColley S; Bowen A; McCoy K; Sakellaris K; Sharma P; Cannon C; Hebert A; Sagel S; Anthony M; Dyson M; Urbanek H; Millard S; Gile C; Graff G; Allwein L; Hiatt P; Schaap N; Krupp N; Bendy L; Ahrens R; Teresi M; Berlinski A; Ramsey LL; McNamara J; Johnson M; Brown R; Berry P; Mehdi N; Royall J; Thomas D; Rubenstein R; Donnelly E; Weiner D; Hurban S; Hartigan E; Powers M; Simmons K; Chatfield B; Oldroyd H; Hoffman L; McNamara S; Wooldridge J; Cooper A; Faro A; Rodgers D; Fortner C; Suttmore V; Hocevar-Trnka J; Skalland M; Fowler A, 2017, 'Effects of diagnosis by newborn screening for cystic fibrosis on weight and length in the first year of life', JAMA Pediatrics, 171, pp. 546 - 554, http://dx.doi.org/10.1001/jamapediatrics.2017.0206

Peng G; Bojadzieva J; Ballinger ML; Li J; Blackford AL; Mai PL; Savage SA; Thomas DM; Strong LC; Wang W, 2017, 'Estimating TP53 mutation carrier probability in families with li-fraumeni syndrome using LFSPRO', Cancer Epidemiology Biomarkers and Prevention, 26, pp. 837 - 844, http://dx.doi.org/10.1158/1055-9965.EPI-16-0695

Lorgelly PK; Doble B; Rowen D; Brazier J; Thomas DM; Fox SB; Thorne H; Parisot JP; Doig K; Fellowes A; Dobrovic A; James PA; Lipton L; Ashley D; Hayes T; McMurrick P; Richardson G; Lucas M; McNeil JJ; John T, 2017, 'Condition-specific or generic preference-based measures in oncology? A comparison of the EORTC-8D and the EQ-5D-3L', Quality of Life Research, 26, pp. 1163 - 1176, http://dx.doi.org/10.1007/s11136-016-1443-y

Doble B; John T; Thomas D; Fellowes A; Fox S; Lorgelly P, 2017, 'Cost-effectiveness of precision medicine in the fourth-line treatment of metastatic lung adenocarcinoma: An early decision analytic model of multiplex targeted sequencing', Lung Cancer, 107, pp. 22 - 35, http://dx.doi.org/10.1016/j.lungcan.2016.05.024

Thway K; Noujaim J; Thomas DM; Fisher C; Jones RL, 2017, 'Myoepithelial Carcinoma of the Paracecal Mesentery: Aggressive Behavior of a Rare Neoplasm at an Unusual Anatomic Site.', Rare Tumors, 9, pp. 6504, http://dx.doi.org/10.4081/rt.2017.6504

Takeda K; Nakayama M; Hayakawa Y; Kojima Y; Ikeda H; Imai N; Ogasawara K; Okumura K; Thomas DM; Smyth MJ, 2017, 'IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting', Nature Communications, 8, http://dx.doi.org/10.1038/ncomms14607

Vargas AC; Selinger CI; Satgunaseelan L; Cooper WA; Gupta R; Stalley P; Brown W; Soper J; Schatz J; Boyle R; Thomas DM; Tattersall MHN; Bhadri VA; Maclean F; Bonar SF; Scolyer RA; Karim RZ; McCarthy SW; Mahar A; O'Toole SA, 2016, 'Atypical Ewing sarcoma breakpoint region 1 fluorescence in-situ hybridization signal patterns in bone and soft tissue tumours: diagnostic experience with 135 cases', Histopathology, 69, pp. 1000 - 1011, http://dx.doi.org/10.1111/his.13031

Lomax AJ; Beith J; Bhadri V; Boyer M; Grimison P; Horvath LG; Kao S; Tattersall M; Thomas D; McNeil C, 2016, 'Outcomes of patients with non-melanoma solid tumours receiving self-funded pembrolizumab at Chris O'Brien Lifehouse', Internal Medicine Journal, 46, pp. 1392 - 1398, http://dx.doi.org/10.1111/imj.13232

Ballinger ML; Thomas DM, 2016, 'Sarcoma and germ-line DICER1 mutations – Authors’ reply', Lancet Oncology, 17, pp. e471, http://dx.doi.org/10.1016/S1470-2045(16)30527-7

Ballinger ML; Goode DL; Ray-Coquard I; James PA; Mitchell G; Niedermayr E; Puri A; Schiffman JD; Dite GS; Cipponi A; Maki RG; Brohl AS; Myklebost O; Stratford EW; Lorenz S; Ahn SM; Ahn JH; Kim JE; Shanley S; Beshay V; Randall RL; Judson I; Seddon B; Campbell IG; Young MA; Sarin R; Blay JY; O'Donoghue SI; Thomas DM, 2016, 'Monogenic and polygenic determinants of sarcoma risk: an international genetic study', Lancet Oncology, 17, pp. 1261 - 1271, http://dx.doi.org/10.1016/S1470-2045(16)30147-4

Kager L; Whelan J; Dirksen U; Hassan B; Anninga J; Bennister L; Bovee JVMG; Brennan B; Broto JM; Brugieres L; Cleton-Jansen A-M; Copland C; Dutour A; Fagioli F; Ferrari S; Fiocco M; Fleuren E; Gaspar N; Gelderblom H; Gerrand C; Gerss J; Gonzato O; van der Graaf W; Hecker-Nolting S; Herrero-Martin D; Klco-Brosius S; Kovar H; Ladenstein R; Lancia C; LeDeley M-C; McCabe MG; Metzler M; Myklebost O; Nathrath M; Picci P; Potratz J; Redini F; Richter GHS; Reinke D; Rutkowski P; Scotlandi K; Strauss S; Thomas D; Tirado OM; Tirode F; Vassal G; Bielack SS, 2016, 'The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report', CLINICAL SARCOMA RESEARCH, 6, http://dx.doi.org/10.1186/s13569-016-0043-5

Lorgelly PK; Doble B; Knott RJ; Thomas DM; Fox SB; Thorne H; Parisot JP; Doig K; Fellowes A; Dobrovic A; Lipton L; Ashley D; Hayes T; McMurrick P; Richardson G; Lucas M; McNeil JJ; John T, 2016, 'Realising the Value of Linked Data to Health Economic Analyses of Cancer Care: A Case Study of Cancer 2015', Pharmacoeconomics, 34, pp. 139 - 154, http://dx.doi.org/10.1007/s40273-015-0343-2

Burgess A; Chia KM; Haupt S; Thomas D; Haupt Y; Lim E, 2016, 'Clinical overview of MDM2/X-targeted therapies', Frontiers in Oncology, 6, http://dx.doi.org/10.3389/fonc.2016.00007

Thomas DM; Ballinger ML, 2016, 'Diagnosis and management of hereditary sarcoma', Recent Results in Cancer Research, 205, pp. 169 - 189, http://dx.doi.org/10.1007/978-3-319-29998-3_10

Ngiow SF; Loi S; Thomas D; Smyth MJ, 2016, 'Mouse Models of Tumor Immunotherapy', Tumor immunology, 130, pp. 1 - 24, http://dx.doi.org/10.1016/bs.ai.2015.12.004

McBride KA; Hallowell N; Tattersall MHN; Kirk J; Ballinger ML; Thomas DM; Mitchell G; Young MA, 2016, 'Timing and context: important considerations in the return of genetic results to research participants', Journal of Community Genetics, 7, pp. 11 - 20, http://dx.doi.org/10.1007/s12687-015-0231-7

Gaston CL; Grimer RJ; Parry M; Stacchiotti S; Dei Tos AP; Gelderblom H; Ferrari S; Baldi GG; Jones RL; Chawla S; Casali P; LeCesne A; Blay J-Y; Dijkstra SPD; Thomas DM; Rutkowski P, 2016, 'Current status and unanswered questions on the use of Denosumab in giant cell tumor of bone', Clinical Sarcoma Research, 6, pp. 15, http://dx.doi.org/10.1186/s13569-016-0056-0

Thomas D, 2016, 'International survey of awareness of genetic risk in the clinical sarcoma community', Asia Pac J Clin Oncol, 12, pp. 133 - 142, http://dx.doi.org/10.1111/ajco.12457

Sampson JN; Wheeler WA; Yeager M; Panagiotou O; Wang Z; Berndt SI; Lan Q; Abnet CC; Amundadottir LT; Figueroa JD; Landi MT; Mirabello L; Savage SA; Taylor PR; De Vivo I; McGlynn KA; Purdue MP; Rajaraman P; Adami HO; Ahlbom A; Albanes D; Amary MF; An SJ; Andersson U; Andriole G; Andrulis IL; Angelucci E; Ansell SM; Arici C; Armstrong BK; Arslan AA; Austin MA; Baris D; Barkauskas DA; Bassig BA; Becker N; Benavente Y; Benhamou S; Berg C; Van Den Berg D; Bernstein L; Bertrand KA; Birmann BM; Black A; Boeing H; Boffetta P; Boutron-Ruault MC; Bracci PM; Brinton L; Brooks-Wilson AR; Bueno-De-Mesquita HB; Burdett L; Buring J; Butler MA; Cai Q; Cancel-Tassin G; Canzian F; Carrato A; Carreon T; Carta A; Chan JKC; Chang ET; Chang GC; Chang IS; Chang J; Chang-Claude J; Chen CJ; Chen CY; Chen C; Chen CH; Chen C; Chen H; Chen K; Chen KY; Chen KC; Chen Y; Chen YH; Chen YS; Chen YM; Chien LH; Chirlaque MD; Choi JE; Choi YY; Chow WH; Chung CC; Clavel J; Clavel-Chapelon F; Cocco P; Colt JS; Comperat E; Conde L; Connors JM; Conti D; Cortessis VK; Cotterchio M; Cozen W; Crouch S; Crous-Bou M; Cussenot O; Davis FG, 2015, 'Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types', Journal of the National Cancer Institute, 107, http://dx.doi.org/10.1093/jnci/djv279

Thomas DM; Fox S; Lorgelly PK; Ashley D; Richardson G; Lipton L; Parisot JP; Lucas M; McNeil J, 2015, 'Cancer 2015: A longitudinal whole-of-system study of genomic cancer medicine', Drug Discovery Today, 20, pp. 1429 - 1432, http://dx.doi.org/10.1016/j.drudis.2015.10.009

Martin JH; Phillips E; Thomas D; Somogyi AA, 2015, 'Adding the 'medicines' back into personalized medicine to improve cancer treatment outcomes', British Journal of Clinical Pharmacology, 80, pp. 929 - 931, http://dx.doi.org/10.1111/bcp.12690

Parisot JP; Thorne H; Fellowes A; Doig K; Lucas M; McNeil JJ; Doble B; Dobrovic A; John T; James PA; Lipton L; Ashley D; Hayes T; McMurrick P; Richardson G; Lorgelly P; Fox SB; Thomas DM, 2015, '“Cancer 2015”: A prospective, population-based cancer cohort—phase 1: Feasibility of genomics-guided precision medicine in the clinic', Journal of Personalized Medicine, 5, pp. 354 - 369, http://dx.doi.org/10.3390/jpm5040354

Papenfuss AT; Thomas DM, 2015, 'The life history of neochromosomes revealed', Molecular and Cellular Oncology, 2, http://dx.doi.org/10.1080/23723556.2014.1000698

Mirabello L; Koster R; Moriarity BS; Spector LG; Meltzer PS; Gary J; Machiela MJ; Pankratz N; Panagiotou OA; Largaespada D; Wang Z; Gastier-Foster JM; Gorlick R; Khanna C; de Toledo SRC; Petrilli AS; Patiño-Garcia A; Sierrasesúmaga L; Lecanda F; Andrulis IL; Wunder JS; Gokgoz N; Serra M; Hattinger C; Picci P; Scotlandi K; Flanagan AM; Tirabosco R; Amary MF; Halai D; Ballinger ML; Thomas DM; Davis S; Barkauskas DA; Marina N; Helman L; Otto GM; Becklin KL; Wolf NK; Weg MT; Tucker M; Wacholder S; Fraumeni JF; Caporaso NE; Boland JF; Hicks BD; Vogt A; Burdett L; Yeager M; Hoover RN; Chanock SJ; Savage SA, 2015, 'A genome-wide scan identifies variants in NFIB associated with metastasis in patients with osteosarcoma', Cancer Discovery, 5, pp. 920 - 931, http://dx.doi.org/10.1158/2159-8290.CD-15-0125

Thomas DM, 2015, 'The growing problem of benign connective tissue tumours', Lancet Oncology, 16, pp. 879 - 880, http://dx.doi.org/10.1016/S1470-2045(15)00147-3

Ballinger ML; Mitchell G; Thomas DM, 2015, 'Surveillance recommendations for patients with germline TP53 mutations', Current Opinion in Oncology, 27, pp. 332 - 337, http://dx.doi.org/10.1097/CCO.0000000000000200

Thomas DM; James PA; Ballinger ML, 2015, 'Clinical implications of genomics for cancer risk genetics', Lancet Oncology, 16, pp. e303 - e308, http://dx.doi.org/10.1016/S1470-2045(15)70026-4

Cassier PA; Maki RG; Wagner AJ; Bompas E; Gelderblom H; Kroep JR; Thomas DM; Italiano A; Seddon BM; Van Der Graaf WTA; Domont J; Blay J-Y; Stacchiotti S, 2015, 'Imatinib mesylate (IM) activity in patients (pts) with locally advanced tenosynovial giant cell tumor/pigmented villonodular synovitis (TGCT).', Journal of Clinical Oncology, 33, pp. 10561 - 10561, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.10561

Chantrill LA; Nagrial AM; Watson C; Johns AL; Martyn-Smith M; Simpson S; Mead S; Jones MD; Samra JS; Gill AJ; Watson N; Chin VT; Humphris JL; Chou A; Brown B; Morey A; Pajic M; Grimmond SM; Chang DK; Thomas D; Sebastian L; Sjoquist K; Yip S; Pavlakis N; Asghari R; Harvey S; Grimison P; Simes J; Biankin AV, 2015, 'Precision medicine for advanced pancreas cancer: The individualized molecular pancreatic cancer therapy (IMPaCT) Trial', Clinical Cancer Research, 21, pp. 2029 - 2037, http://dx.doi.org/10.1158/1078-0432.CCR-15-0426

Thomas DM; Wood MA, 2015, 'THE EMERGENCE OF NEGATIVE SUPERHUMPS IN CATACLYSMIC VARIABLES: SMOOTHED PARTICLE HYDRODYNAMICS SIMULATIONS', ASTROPHYSICAL JOURNAL, 803, http://dx.doi.org/10.1088/0004-637X/803/2/55

Wong SQ; Fellowes A; Doig K; Ellul J; Bosma TJ; Irwin D; Vedururu R; Tan AYC; Weiss J; Chan KS; Lucas M; Thomas DM; Dobrovic A; Parisot JP; Fox SB, 2015, 'Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients', British Journal of Cancer, 112, pp. 1411 - 1420, http://dx.doi.org/10.1038/bjc.2015.80

Thomas DM; Ballinger ML, 2015, 'Etiologic, environmental and inherited risk factors in sarcomas', Journal of Surgical Oncology, 111, pp. 490 - 495, http://dx.doi.org/10.1002/jso.23809

Ashley D; Thomas D; Gore L; Carter R; Zalcberg JR; Otmar R; Savulescu J, 2015, 'Accepting risk in the acceleration of drug development for rare cancers', Lancet Oncology, 16, pp. e190 - e194, http://dx.doi.org/10.1016/S1470-2045(14)71153-2

Tattersall MHN; Thomas DM, 2015, 'Distinguishing activity from progress', Lancet Oncology, 16, pp. 1586 - 1588, http://dx.doi.org/10.1016/S1470-2045(15)00466-0

Neuhaus SJ; Thomas D; Desai J; Vuletich C; Von Dincklage J; Olver I, 2015, 'Wiki-based clinical practice guidelines for the management of adult onset sarcoma: A new paradigm in sarcoma evidence', Sarcoma, 2015, http://dx.doi.org/10.1155/2015/614179

Lewin J; Khamly KK; Young RJ; Mitchell C; Hicks RJ; Toner GC; Ngan SYK; Chander S; Powell GJ; Herschtal A; Te Marvelde L; Desai J; Choong PFM; Stacker SA; Achen MG; Ferris N; Fox S; Slavin J; Thomas DM, 2014, 'A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma', British Journal of Cancer, 111, pp. 2254 - 2261, http://dx.doi.org/10.1038/bjc.2014.537

Wang Z; Zhu B; Zhang M; Parikh H; Jia J; Chung CC; Sampson JN; Hoskins JW; Hutchinson A; Burdette L; Ibrahim A; Hautman C; Raj PS; Abnet CC; Adjei AA; Ahlbom A; Albanes D; Allen NE; Ambrosone CB; Aldrich M; Amiano P; Amos C; Andersson U; Gerald Andriole GA; Andrulis IL; Arici C; Arslan AA; Austin MA; Baris D; Barkauskas DA; Bassig BA; Freeman LEB; Berg CD; Berndt SI; Bertazzi PA; Biritwum RB; Black A; Blot W; Boeing H; Boffetta P; Bolton K; Boutron-Ruault MC; Bracci PM; Brennan P; Brinton LA; Brotzman M; Bueno-de-Mesquita HB; Buring JE; Butler MA; Cai Q; Cancel-Tassin G; Canzian F; Cao G; Caporaso NE; Carrato A; Carreon T; Carta A; Chang GC; Chang IS; Chang-Claude J; Che X; Chen CJ; Chen CY; Chen CH; Chen C; Chen KY; Chen YM; Chokkalingam AP; Chu LW; Clavel-Chapelon F; Colditz GA; Colt JS; Conti D; Cook MB; Cortessis VK; Crawford ED; Cussenot O; Davis FG; De Vivo I; Deng X; Ding T; Dinney CP; Di Stefano AL; Diver WR; Duell EJ; Elena JW; Fan JH; Feigelson HS; Feychting M; Figueroa JD; Flanagan AM; Fraumeni JF; Freedman ND; Fridley BL; Fuchs CS; Gago-Dominguez M; Gallinger S; Gao YT; Gapstur SM; Garcia-Closas M, 2014, 'Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33', Human Molecular Genetics, 23, pp. 6616 - 6633, http://dx.doi.org/10.1093/hmg/ddu363

Garsed DW; Marshall OJ; Corbin VDA; Hsu A; DiStefano L; Schröder J; Li J; Feng ZP; Kim BW; Kowarsky M; Lansdell B; Brookwell R; Myklebost O; Meza-Zepeda L; Holloway AJ; Pedeutour F; Choo KHA; Damore MA; Deans AJ; Papenfuss AT; Thomas DM, 2014, 'The Architecture and Evolution of Cancer Neochromosomes', Cancer Cell, 26, pp. 653 - 667, http://dx.doi.org/10.1016/j.ccell.2014.09.010

Kansara M; Teng MW; Smyth MJ; Thomas DM, 2014, 'Translational biology of osteosarcoma', Nature Reviews Cancer, 14, pp. 722 - 735, http://dx.doi.org/10.1038/nrc3838

Gallagher* L; Li W; Ray R; Romano M; Wernli K; Gao D; Thomas D; Checkoway H, 2014, 'Occupational Exposures and Risk of Stomach and Esophageal Cancer among a Cohort of Female Textile Workers in Shanghai, China', ISEE Conference Abstracts, 2014, http://dx.doi.org/10.1289/isee.2014.p3-735

Wong SQ; Li J; Tan AYC; Vedururu R; Pang JMB; Do H; Ellul J; Doig K; Bell A; Macarthur GA; Fox SB; Thomas DM; Fellowes A; Parisot JP; Dobrovic A, 2014, 'Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing', BMC Medical Genomics, 7, http://dx.doi.org/10.1186/1755-8794-7-23

Pishas KI; Neuhaus SJ; Clayer MT; Schreiber AW; Lawrence DM; Perugini M; Whitfield RJ; Farshid G; Manavis J; Chryssidis S; Mayo BJ; Haycox RC; Ho K; Brown MP; D'Andrea RJ; Evdokiou A; Thomas DM; Desai J; Callen DF; Neilsen PM, 2014, 'Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling', Cancer Research, 74, pp. 921 - 931, http://dx.doi.org/10.1158/0008-5472.CAN-13-2424

Cox BM; Shah MM; Cichon T; Tancer ME; Galloway MP; Thomas DM; Perrine SA, 2014, 'Behavioral and neurochemical effects of repeated MDMA administration during late adolescence in the rat.', Prog Neuropsychopharmacol Biol Psychiatry, 48, pp. 229 - 235, http://dx.doi.org/10.1016/j.pnpbp.2013.09.021

McBride KA; Ballinger ML; Killick E; Kirk J; Tattersall MHN; Eeles RA; Thomas DM; Mitchell G, 2014, 'Li-Fraumeni syndrome: Cancer risk assessment and clinical management', Nature Reviews Clinical Oncology, 11, pp. 260 - 271, http://dx.doi.org/10.1038/nrclinonc.2014.41

Kansara M; Thomas DM, 2014, 'RB1-mediated cell-autonomous and hostdependent oncosuppressor mechanisms in radiation-induced osteosarcoma', Oncoimmunology, 3, http://dx.doi.org/10.4161/onci.27569

Cipponi A; Thomas DM, 2014, 'Stress-induced cellular adaptive strategies: Ancient evolutionarily conserved programs as new anticancer therapeutic targets', Bioessays, 36, pp. 552 - 560, http://dx.doi.org/10.1002/bies.201300170

Anninga JK; Cleton-Jansen A-M; Hassan B; Amary MF; Baumhoer D; Blay J-Y; Brugieres L; Ferrari S; Jurgens H; Kempf-Bielack B; Kovar H; Myklebost O; Nathrath M; Picci P; Riegman P; Schilham MW; Soliman R; Stark DP; Strauss S; Sydes M; Tarpey P; Thomas D; Whelan J; Wilhelm M; Zamzam M; Gelderblom H; Bielack SS, 2014, 'Workshop report on the 2nd Joint ENCCA/EuroSARC European bone sarcoma network meeting: integration of clinical trials with tumour biology', CLINICAL SARCOMA RESEARCH, 4, http://dx.doi.org/10.1186/2045-3329-4-4

Checkoway H; Lundin J; Costello S; Ray R; Li W; Eisen E; Astrakianakis G; Seixas N; Applebaum K; Li Gao D; Thomas D, 2014, '0347 Possible pro-carcinogenic effect of endotoxin on lung cancer in an extended follow-up of Shanghai women textile workers', Occupational and Environmental Medicine, 71, pp. A42.3 - A43, http://dx.doi.org/10.1136/oemed-2014-102362.131

Bandopadhayay P; Jabbour AM; Riffkin C; Salmanidis M; Gordon L; Popovski D; Rigby L; Ashley DM; Watkins DN; Thomas DM; Algar E; Ekert PG, 2013, 'The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts', BMC Cancer, 13, http://dx.doi.org/10.1186/1471-2407-13-585

Kansara M; Leong HS; Lin DM; Popkiss S; Pang P; Garsed DW; Walkley CR; Cullinane C; Ellul J; Haynes NM; Hicks R; Kuijjer ML; Cleton-Jansen AM; Hinds PW; Smyth MJ; Thomas DM, 2013, 'Immune response to rb1-Regulated senescence limits radiation-Induced osteosarcoma formation', Journal of Clinical Investigation, 123, pp. 5351 - 5360, http://dx.doi.org/10.1172/JCI70559

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