By Dr Steven Thomas Leach

Journal articles

Lwin ZZK; Leach ST; Krishnan U, 2025, 'The Role of Vitamin D in Eosinophilic Esophagitis in Children', Journal of Paediatrics and Child Health, 61, pp. 1407 - 1414, http://dx.doi.org/10.1111/jpc.70126

O’Donnell JEM; Leach ST; Bowcock NL; Chen S; Gupta N; Jiang K; Lopez RN; Messenger R; Nahidi L; Shapiro A; Day AS; Lemberg DA, 2025, 'Correction: Daily Vitamin D3 Versus Stoss Vitamin D3 for Correction of 25OHD Deficiency in Children with Inflammatory Bowel Disease, a Randomised Controlled Trial (Digestive Diseases and Sciences, (2025), 70, 5, (1844-1853), 10.1007/s10620-025-08913-3)', Digestive Diseases and Sciences, 70, pp. 2549 - 2550, http://dx.doi.org/10.1007/s10620-025-09061-4

O’Donnell JEM; Leach ST; Bowcock NL; Chen S; Gupta N; Jiang K; Lopez RN; Messenger R; Nahidi L; Shapiro A; Day AS; Lemberg DA, 2025, 'Daily Vitamin D3 Versus Stoss Vitamin D3 for Correction of 25OHD Deficiency in Children with Inflammatory Bowel Disease, a Randomised Controlled Trial', Digestive Diseases and Sciences, 70, pp. 1844 - 1853, http://dx.doi.org/10.1007/s10620-025-08913-3

Little R; Jayawardana T; Zhang F; Houshyar Y; Koentgen S; Wu N; Ellepola A; Tavakoli P; Chung A; Ho A; Read S; Boussioutas A; Ward M; Sparrow M; Gibson P; Ghaly S; Corte C; Talley N; Leach S; Lemberg D; Dutt S; Paramsothy S; Leong R; Connor S; Hold G, 2025, 'Association of gut microbiota changes and disease activity in patients with Crohn's disease and ulcerative colitis: baseline data from the Australian IBD Microbiome study', JOURNAL OF CROHNS & COLITIS, 19, pp. i2425 - i2426, http://dx.doi.org/10.1093/ecco-jcc/jjae190.1519

Koentgen S; Cosier D; Tavakoli P; Leach ST; Dutt S; Ghaly S; Connor SJ; Lemberg DA; Lambert K; Hold GL, 2025, 'Fat rich dietary habits: Further increasing IBD risk in first degree relatives', JOURNAL OF CROHNS & COLITIS, 19, pp. i356 - i356, http://dx.doi.org/10.1093/ecco-jcc/jjae190.0192

Little R; Jayawardana T; Zhang F; Koentgen S; Wu N; Tavakoli P; Chung A; Ho A; Read S; Boussioutas A; Ward M; Sparrow M; Gibson P; Ghaly S; Corte C; Talley N; Leach S; Lemberg D; Dutt S; Paramsothy S; Leong R; Connor S; Hold G, 2025, 'Gut microbiota changes are associated with type of advanced therapy in patients with Inflammatory Bowel Disease: baseline data from the Australian IBD Microbiome study', JOURNAL OF CROHNS & COLITIS, 19, pp. i2413 - i2415, http://dx.doi.org/10.1093/ecco-jcc/jjae190.1514

Jayawardana T; Little RD; Zhang F; Koentgen S; Wu N; Houshyar Y; Tavakoli P; Boussioutas A; Ward MG; Sparrow MP; Gibson PR; Ghaly S; Corte C; Talley NJ; Leach S; Lemberg D; Dutt S; Paramsothy S; Leong R; Connor SJ; Hold G; Australia IBDMAIMS, 2025, 'Impaired health-related quality of life is associated with alterations in gut microbiota signatures in patients with Inflammatory Bowel Disease: baseline data from the Australian IBD Microbiome study', JOURNAL OF CROHNS & COLITIS, 19, pp. i2422 - i2424, http://dx.doi.org/10.1093/ecco-jcc/jjae190.1518

Jayawardana T; Little RD; Zhang F; Koentgen S; Wu N; Tavakoli P; Sidhu S; Le A; Boussioutas A; Ward MG; Miles S; Gibson PR; Ghaly S; Corte C; Talley NJ; Leach S; Lemberg D; Dutt S; Paramsothy S; Leong R; Connor SJ; Hold G; Australia IBDMAIMS, 2025, 'Microbial signatures associated with Inflammatory Bowel Disease in Australia: baseline data from the Australian IBD Microbiome study', JOURNAL OF CROHNS & COLITIS, 19, pp. i2391 - i2392, http://dx.doi.org/10.1093/ecco-jcc/jjae190.1501

Cosier D; Lambert K; Karen C; Batterham M; Little RD; Wu N; Tavakoli P; Ghaly S; Pipicella JL; Connor S; Leach S; Lemberg D; Houshyar Y; Jayawardana T; Koentgen S; Hold G, 2025, 'The interplay between dietary intake and disease activity in Australian adults with and without Inflammatory Bowel Disease', JOURNAL OF CROHNS & COLITIS, 19, pp. I1468 - I1468, http://dx.doi.org/10.1093/ecco-jcc/jjae190.0933

Ahmed T; Lemberg DA; Day AS; Leach ST, 2025, 'The Interplay Between Immunological Status and Gut Microbial Dysbiosis in the Development of the Symptoms of Irritable Bowel Syndrome: A Systematic Review with Meta-Analysis', Digestive Diseases and Sciences, http://dx.doi.org/10.1007/s10620-025-09360-w

Jayawardana TC; Little RD; Zhang F; Koentgen S; Wu N; Houshyar Y; Tavakoli P; Boussioutas A; Ward M; Sparrow M; Gibson PR; Ghaly S; Corte C; Talley NJ; Leach ST; Lemberg DA; Dutt S; Paramsothy S; Leong RW; Connor SJ; Hold GL, 2025, 'Mo1960: IMPAIRED HEALTH-RELATED QUALITY OF LIFE IS ASSOCIATED WITH ALTERATIONS IN GUT MICROBIOTA SIGNATURES IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: BASELINE DATA FROM THE AUSTRALIAN IBD MICROBIOME STUDY.', Gastroenterology, 169, pp. S - 1243, http://dx.doi.org/10.1016/s0016-5085(25)03747-3

Little RD; Jayawardana TC; Zhang F; Koentgen S; Wu N; Tavakoli P; Chung A; Ho A; Read S; Boussioutas A; Ward M; Sparrow M; Gibson PR; Ghaly S; Corte C; Talley NJ; Leach ST; Lemberg DA; Dutt S; Paramsothy S; Leong R; Connor SJ; Hold GL, 2025, 'Sa1795: GUT MICROBIOTA CHANGES ARE ASSOCIATED WITH TYPE OF ADVANCED THERAPY IN PATIENTS WITH IBD: BASELINE DATA FROM THE AUSTRALIAN IBD MICROBIOME STUDY', Gastroenterology, 169, pp. S - 532, http://dx.doi.org/10.1016/s0016-5085(25)02163-8

Little RD; Jayawardana TC; Zhang F; Houshyar Y; Koentgen S; Dutt S; Leach ST; Lemberg DA; Hold GL, 2025, 'Tu2093: DISTINCT MICROBIAL SIGNATURES ARE ASSOCIATED WITH PEDIATRIC INFLAMMATORY BOWEL DISEASE - BASELINE DATA FROM THE AUSTRALIAN IBD MICROBIOME STUDY', Gastroenterology, 169, http://dx.doi.org/10.1016/s0016-5085(25)04560-3

Cosier D; Lambert K; Charlton K; Batterham M; Little RD; Wu N; Tavakoli P; Ghaly S; Pipicella JL; Connor S; Leach S; Lemberg DA; Houshyar Y; Jayawardana T; Koentgen S; Hold GL, 2024, 'Dietary Patterns and Fibre Intake Are Associated with Disease Activity in Australian Adults with Inflammatory Bowel Disease: An Exploratory Dietary Pattern Analysis †', Nutrients, 16, http://dx.doi.org/10.3390/nu16244349

Krishnan U; Tang TC; Coffey MJ; Leach ST, 2024, 'Reply to “Proton pump inhibitors and esophageal atresia: Too early to change clinical practice”', Journal of Pediatric Gastroenterology and Nutrition, 79, pp. 1218 - 1220, http://dx.doi.org/10.1002/jpn3.12374

Chatterjee S; Leach ST; Lui K; Mishra A, 2024, 'Symbiotic symphony: Understanding host-microbiota dialogues in a spatial context', Seminars in Cell and Developmental Biology, 161-162, pp. 22 - 30, http://dx.doi.org/10.1016/j.semcdb.2024.03.001

Katsoudas N; Tavakoli P; Wu N; Shapiro A; Leach ST; Williams AJ; Paramsothy R; Ghaly S; Connor SJ; Samocha-Bonet D; Lambert K; Hold GL, 2024, 'Dietary Emulsifier Exposure in People with Inflammatory Bowel Disease Compared with Healthy Controls: Is There a Cause for Concern?', Inflammatory Bowel Diseases, 30, pp. 1241 - 1250, http://dx.doi.org/10.1093/ibd/izad318

Tang TC; Leach ST; Krishnan U, 2024, 'Proton pump inhibitors, antibiotics, and atopy increase the risk of eosinophilic esophagitis in children with esophageal atresia', Journal of Pediatric Gastroenterology and Nutrition, 78, pp. 1317 - 1328, http://dx.doi.org/10.1002/jpn3.12129

Zama D; Leach ST, 2024, 'Editorial: Health informatics in pediatric gastroenterology, hepatology & nutrition', Frontiers in Pediatrics, 12, http://dx.doi.org/10.3389/fped.2024.1458319

Traini I; Chan SY; Menzies J; Hughes J; Coffey MJ; McKay IR; Ooi CY; Leach ST; Krishnan U, 2024, 'Intestinal dysbiosis and inflammation in children with repaired esophageal atresia', Journal of Pediatric Gastroenterology and Nutrition, 78, pp. 43 - 51, http://dx.doi.org/10.1002/jpn3.12053

Leach ST, 2024, 'Role of Probiotics and Prebiotics in Gut Symbiosis', Nutrients, 16, http://dx.doi.org/10.3390/nu16020238

Dissanayake RY; Yuan H; Coffey MJ; Traini I; Chan SY; Menzies J; Hughes J; McKay I; van Dorst JM; Leach ST; Chee OY; Krishnan U, 2024, '343 ARE AIRWAY MICROBIOTA AND INFLAMMATION IN CHILDREN WITH ESOPHAGEAL ATRESIA RELATED TO REFLUX ASPIRATION?', Gastroenterology, 166, pp. S - 80, http://dx.doi.org/10.1016/s0016-5085(24)00681-4

Wong PY; Yip C; Lemberg DA; Day AS; Leach ST, 2023, 'Evolution of a Pathogenic Microbiome', Journal of Clinical Medicine, 12, http://dx.doi.org/10.3390/jcm12227184

Menzies J; Sundararaj A; Cardamone M; McHarg A; Leach S; Krishnan U, 2023, 'Ketogenic Diets in Children With Intractable Epilepsy and its Effects on Gastrointestinal Function, Gut Microbiome, Inflammation, and Quality of Life', Journal of Pediatric Gastroenterology and Nutrition, 77, pp. 679 - 685, http://dx.doi.org/10.1097/MPG.0000000000003928

Lopez RN; Leach ST; Bowcock N; Coker E; Shapiro AJ; Day AS; Lemberg DA, 2023, 'Differences in Gut Microbiome Profile between Healthy Children and Children with Inflammatory Bowel Disease and/or Autoimmune Liver Disease: A Case-Control Study', Pathogens, 12, http://dx.doi.org/10.3390/pathogens12040585

Mah C; Jayawardana T; Leong G; Koentgen S; Lemberg D; Connor SJ; Rokkas T; Grimm MC; Leach ST; Hold GL, 2023, 'Assessing the Relationship between the Gut Microbiota and Inflammatory Bowel Disease Therapeutics: A Systematic Review', Pathogens, 12, http://dx.doi.org/10.3390/pathogens12020262

Makeyeva Y; Leach ST; Ryugo DK, 2023, 'Mast cells in the Milieu: A comparative study in the tongue and liver', Proceedings of the Shevchenko Scientific Society Medical Sciences, 72, http://dx.doi.org/10.25040/NTSH2023.02.10

Tang T; Leach ST; Krishnan U, 2022, '283. DOES PROTON PUMP INHIBITOR EXPOSURE INCREASE THE RISK OF DEVELOPING EOSINOPHILIC ESOPHAGITIS IN CHILDREN WITH ESOPHAGEAL ATRESIA?', Diseases of the Esophagus, 35, http://dx.doi.org/10.1093/dote/doac051.283

Volkers AG; Appleton L; Gearry RB; Frampton CM; de Voogd FAE; Peters van Ton AM; Leach ST; Lemberg DA; Day AS, 2022, 'Fecal Calprotectin, Chitinase 3-Like-1, S100A12 and Osteoprotegerin as Markers of Disease Activity in Children with Crohn’s Disease', Gastrointestinal Disorders, 4, pp. 180 - 189, http://dx.doi.org/10.3390/gidisord4030017

Chandrasekar N; Dehlsen K; Leach ST; Krishnan U, 2022, 'Blenderised Tube Feeds vs. Commercial Formula: Which Is Better for Gastrostomy-Fed Children?', Nutrients, 14, http://dx.doi.org/10.3390/nu14153139

Traini I; Chan SY; Menzies J; Hughes J; Coffey MJ; Katz T; McKay IR; Ooi CY; Leach ST; Krishnan U, 2022, 'Evaluating the Dietary Intake of Children with Esophageal Atresia: A Prospective, Controlled, Observational Study', Journal of Pediatric Gastroenterology and Nutrition, 75, pp. 221 - 226, http://dx.doi.org/10.1097/MPG.0000000000003498

Wong E; Lui K; Day AS; Leach ST, 2022, 'Manipulating the neonatal gut microbiome: current understanding and future perspectives', Archives of Disease in Childhood Fetal and Neonatal Edition, 107, pp. F346 - F350, http://dx.doi.org/10.1136/archdischild-2021-321922

Lu LDW; Singh H; Castaño-Rodríguez N; Leach ST; Riordan SM; Tedla N; Krishnan U; Kaakoush NO, 2022, 'Changes to the upper gastrointestinal microbiotas of children with reflux oesophagitis and oesophageal metaplasia', Microbial Genomics, 8, http://dx.doi.org/10.1099/mgen.0.000870

McHarg AS; Leach S, 2022, 'The role of the gut microbiome in paediatric irritable bowel syndrome', Aims Microbiology, 8, pp. 454 - 469, http://dx.doi.org/10.3934/microbiol.2022030

MAKEYEVA Y; NICOL C; LEACH ST; De GRAAF SP; LEDGER WL; RYUGO DK, 2022, 'Immunolocalisation of Olfactory Signalling Molecules in Spermatozoa', Fertility & Reproduction, 04, pp. 196 - 196, http://dx.doi.org/10.1142/s2661318222741078

Chandrasekar N; Dehlsen K; Leach ST; Krishnan U, 2021, 'Exploring Clinical Outcomes and Feasibility of Blended Tube Feeds in Children', Journal of Parenteral and Enteral Nutrition, 45, pp. 685 - 698, http://dx.doi.org/10.1002/jpen.2062

Williams AJ; Paramsothy R; Wu N; Ghaly S; Leach S; Paramsothy S; Corte C; O'Brien C; Burke C; Wark G; Samocha-Bonet D; Lambert K; Ahlenstiel G; Wasinger V; Dutt S; Pavli P; Grimm M; Lemberg D; Connor S; Leong R; Hold G, 2021, 'Australia IBD Microbiome (AIM) Study: Protocol for a multicentre longitudinal prospective cohort study', BMJ Open, 11, http://dx.doi.org/10.1136/bmjopen-2020-042493

Krishnan U; Singh H; Tedla N; Leach ST; Kaakoush NO, 2020, 'Presence of gastric pepsinogen in the trachea is associated with altered inflammation and microbial composition', Infection and Immunity, 88, http://dx.doi.org/10.1128/IAI.00455-20

Ali F; Lui K; Wang A; Day AS; Leach ST, 2020, 'The perinatal period, the developing intestinal microbiome and inflammatory bowel diseases: What links early life events with later life disease?', Journal of the Royal Society of New Zealand, 50, pp. 371 - 383, http://dx.doi.org/10.1080/03036758.2019.1706586

Leach ST; Day AS; Messenger R; Walters TD; Navas-López VM; Sladek M; Brückner A; Yerushalmi B; Saeed S; Otley A; Mack D; Gavish M; Turner D; Griffiths AM; Lemberg DA, 2020, 'Fecal Markers of Inflammation and Disease Activity in Pediatric Crohn Disease: Results from the ImageKids Study', Journal of Pediatric Gastroenterology and Nutrition, 70, pp. 580 - 585, http://dx.doi.org/10.1097/MPG.0000000000002615

Traini I; Menzies J; Hughes J; Leach ST; Krishnan U, 2020, 'Oesophageal atresia: The growth gap', World Journal of Gastroenterology, 26, pp. 1262 - 1272, http://dx.doi.org/10.3748/WJG.V26.I12.1262

Upendran Y; Leach ST; Singh H; McBride J; Thomas PS; Belessis Y; Krishnan U, 2020, 'Pepsin as a Marker of Reflux Aspiration in Children With Esophageal Atresia: A Pilot Study', Frontiers in Pediatrics, 8, pp. 94, http://dx.doi.org/10.3389/fped.2020.00094

Traini I; Menzies J; Hughes J; Katz T; Coffey MJ; Ooi CY; Leach ST; Krishnan U; the EARTHRGOBO, 2020, '307 LOOKING BEYOND THE ESOPHAGUS: INVESTIGATING THE INTESTINAL MICROBIOTA AND INFLAMMATION IN CHILDREN WITH REPAIRED ESOPHAGEAL ATRESIA', Gastroenterology, 158, http://dx.doi.org/10.1016/s0016-5085(20)34438-3

Traini I; Menzies J; Hughes J; Katz T; Coffey MJ; Ooi CY; Leach ST; Krishnan U; Group EARTHR, 2020, 'Mo2000 FOOD FOR THOUGHT: DIET, DYSPHAGIA AND GROWTH IN CHILDREN WITH REPAIRED ESOPHAGEAL ATRESIA', Gastroenterology, 158, pp. S - 1575, http://dx.doi.org/10.1016/s0016-5085(20)34618-7

Lum A; Wakefield CE; Donnan B; Burns MA; Fardell JE; Jaffe A; Kasparian NA; Kennedy SE; Leach ST; Lemberg DA; Marshall GM, 2019, 'Facilitating engagement with school in students with chronic illness through positive education: A mixed-methods comparison study', School Psychology, 34, pp. 677 - 686, http://dx.doi.org/10.1037/spq0000315

Lum A; Wakefield CE; Donnan B; Burns MA; Fardell JE; Jaffe A; Kasparian NA; Kennedy SE; Leach ST; Lemberg DA; Marshall GM, 2019, 'School students with chronic illness have unmet academic, social, and emotional school needs', School Psychology, 34, pp. 627 - 636, http://dx.doi.org/10.1037/spq0000311

Thurgate LE; Lemberg DA; Day AS; Leach ST, 2019, 'An overview of inflammatory bowel disease unclassified in children', Inflammatory Intestinal Diseases, 4, pp. 97 - 103, http://dx.doi.org/10.1159/000501519

Krishnan U; Singh H; Kaakoush N; Leach S, 2019, 'DOZ047.18: Diagnosing reflux aspiration in esophageal atresia: role of microbiome and pepsin', Diseases of the Esophagus, 32, http://dx.doi.org/10.1093/dote/doz047.18

Day AS; Ho SSC; Leach ST, 2019, 'Letter to the Editor Re: Serum Calprotectin in Adolescents with Inflammatory Bowel Disease', Journal of Pediatric Gastroenterology and Nutrition, 68, pp. e109, http://dx.doi.org/10.1097/MPG.0000000000002345

Volkers A; Appleton L; Leach ST; Lemberg D; Day AS, 2019, 'Sa1761 – Chitinase 3-Like-1 Protein: A Novel Biomarker of Disease Activity and Risk of Relapse in Children with Inflammatory Bowel Disease', Gastroenterology, 156, pp. S - 391, http://dx.doi.org/10.1016/s0016-5085(19)37828-x

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