By Dr Shafagh Waters

Preprints

Umashankar B; Capraro A; Vijayan A; Wong SL; Nielsen BU; Zhong L; Raftery M; Allan K; Ooi CY; Sivam S; Visser S; Prentice BJ; Fawcett L; Kovacevic Z; Eliasson L; Faurholt-Jepsen D; Jaffe A; Shaw JAM; Vafaee F; Waters SA, 2025, Serum Exosomal Multi-Omic Signatures Stratify Glucose Tolerance in Cystic Fibrosis and Reveal Partial Therapeutic Reprogramming by CFTR Modulators, http://dx.doi.org/10.1101/2025.07.07.25331056

Fawcett L; Chew Z; Schneider-Futschik E; Allan K; Patel H; Jaffe A; Waters S, 2025, INTEGRATING GENOMIC AND FUNCTIONAL TESTING TO IMPROVE CFTR MODULATOR RESPONSE PREDICTION IN CHILDREN WITH CYSTIC FIBROSIS, http://dx.doi.org/10.1101/2025.07.09.25331152

Aggarwal A; Ognenovska S; Ison T; Fichter C; Milogiannakis V; Afzal M; Stella AO; Waters S; Esneau C; Bartlett N; Pöhlmann S; Hoffmann M; Burrell L; Patel S; Ellis S; Wehrhahn M; Martinez E; Ginn A; Churchill M; Angelovich T; Rawlinson W; Yeang M; Kok J; Sintchenkov V; Parry R; Sng J; Neely G; Moreno C; Loo L; Kelleher A; Brilot F; Khromykh A; Turville S, 2025, Replication of SARS-CoV-2 Omicron lineages is defined by TMPRSS2 use in environments where ACE2 is complexed with solute carriers SLC6A19 and SLC6A20, http://dx.doi.org/10.1101/2025.07.07.663433

Gödde N; O’Brien C; Vincan E; Vashi A; Olliff S; Tran B; Waters S; Goldie S; van Vuren PJ; Riddell S; Bruce M; Agarwal V; Athan E; Blasdell K; Chahal S; Creek D; Faheem ; Jain H; Kirkpatrick C; Kumar A; MacRaild C; Muzaffar-Ur-Rehman M; Sankaranarayanan M; Shah R; Styles I; Tachedjian M; Trevaskis N; Singanallur N; McAuley A; Vasan S, 2024, Use of Stem Cell-Derived Cardiomyocyte and Nasal Epithelium Models to Establish a Multi-Tissue Model Platform to Validate Repurposed Drugs Against SARS-CoV-2 Infection, http://dx.doi.org/10.1101/2024.05.22.595397

Chang JJ-Y; Grimley S; Tran BM; Deliyannis G; Tumpach C; Steinig E; Wong SL; Waters SA; Stinear TP; Pitt ME; Purcell D; Vincan E; Coin LJM, 2023, Uncovering strain- and age-dependent differences in innate immune response to SARS-CoV-2 infection in nasal epithelia using 10X single-cell sequencing, http://dx.doi.org/10.1101/2023.03.04.531075

McIntyre K; Waters S; Zhong L; Hart-Smith G; Raftery M; Graves JM; Waters P, 2023, Functional coherence of theXistandRSXprotein interactomes: X chromosome inactivation in marsupials, http://dx.doi.org/10.1101/2023.10.08.560959

Lister N; Milton A; Patel H; Waters S; Hanrahan B; McIntyre K; Livernois A; Wee LK; Ringel A; Mundlos S; Robson M; Shearwin-Whyatt L; Grützner F; Marshall Graves J; Ruiz-Herrera A; Waters P, 2023, Incomplete transcriptional dosage compensation of vertebrate sex chromosomes is balanced by post-transcriptional compensation, http://dx.doi.org/10.1101/2023.02.23.529605

Westhaus A; Cabanes-Creus M; Dilworth KL; Zhu E; Gómez DS; Navarro RG; Amaya AK; Scott S; Kwiatek M; McCorkindale AL; Hayman TE; Frahm S; Perocheau DP; Tran BM; Vincan E; Wong SL; Waters SA; Wilson LOW; Baruteau J; Diecke S; González-Aseguinolaza G; Santilli G; Thrasher AJ; Alexander IE; Lisowski L, 2022, Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors, http://dx.doi.org/10.1101/2022.09.28.510021

Poursani EM; Mercatelli D; Raninga P; Bell JL; Saletta F; Kohane FV; Zheng Y; Rouaen J; Jue TR; Michniewicz FT; Kasiou E; Tsoli M; Cirillo G; Waters S; Shai-Hee T; Valli E; Brettle M; Whan R; Vahadat L; Ziegler D; Lock JG; Giorgi FM; Khanna KK; Vittorio O, 2022, Copper chelation inhibits TGF-βpathways and suppresses epithelial-mesenchymal transition in cancer, http://dx.doi.org/10.1101/2022.10.03.510707

Wong S; Awatade N; Astore M; Allan K; Carnell M; Slapetova I; Chen P-C; Capraro A; Fawcett L; Whan R; Griffith R; Ooi C; Kuyucak S; Jaffe A; Waters S, 2021, In silicoand functional characterisation of an ultra-rareCFTRmutation identifies novel lasso motif interactions regulating channel gating, http://dx.doi.org/10.1101/2021.12.12.472297

Wong S; Awatade N; Astore M; Allan K; Carnell M; Slapetova I; Chen P-C; Setiadi J; Pandzic E; Fawcett L; Widger J; Whan R; Griffith R; Ooi C; Kuyucak S; Jaffe A; Waters S, 2021, Molecular dynamics and theratyping in airway and gut organoids reveal R352Q-CFTR conductance defect, http://dx.doi.org/10.1101/2021.08.11.456003

Azad AKM; Fatima S; Vafaee F, 2020, An Integrative Resource for Network-Based Investigation of COVID-19 Combinatorial Drug Repositioning and Mechanism of Action, http://dx.doi.org/10.26434/chemrxiv.13271096

Hewson C; Capraro A; Wong S; Pandzic E; Fernando BSM; Awatade N; Zhong L; Hart-Smith G; Whan R; Thomas S; Jaffe A; Bridge W; Waters S, 2020, Novel antioxidant therapy with the immediate precursor to glutathione, γ-glutamylcysteine (GGC), ameliorates LPS-induced cellular stress in anin vitrocystic fibrosis model, http://dx.doi.org/10.1101/2020.05.27.119990

Awatade N; Wong S; Pandzic E; Slapetova I; Capraro A; Zhong L; Turgutoglu N; Fawcett L; Whan R; Jaffe A; Waters S, 2020, Significant functional differences despite morphological and molecular similarity in fully differentiated matched Conditionally Reprogrammed (CRC) and Feeder free dual SMAD inhibited expanded human nasal epithelial cells, http://dx.doi.org/10.1101/2020.05.29.120006

Sprague D; Waters SA; Kirk JM; Wang JR; Samollow PB; Waters PD; Calabrese JM, 2019, Non-linear sequence similarity between the Xist and Rsx long noncoding RNAs suggests shared functions of tandem repeat domains, http://dx.doi.org/10.1101/630475

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