By Dr Russell Pickford

Book Chapters

Pickford R, 2019, 'Mass Spectrometry-Based Metabolomic Analysis', in Encyclopedia of Bioinformatics and Computational Biology Abc of Bioinformatics, pp. 410 - 425, http://dx.doi.org/10.1016/B978-0-12-809633-8.20252-5

Pickford R, 2019, 'Mass Spectrometry-Based Metabolomic Analysis', in Encyclopedia of Bioinformatics and Computational Biology, Elsevier, pp. 478 - 494, http://dx.doi.org/10.1016/b978-0-323-95502-7.00322-5

Pickford R, 2018, 'Mass spectrometry-based metabolomic analysis', in Encyclopedia of Bioinformatics and Computational Biology Abc of Bioinformatics, pp. 410 - 425, http://dx.doi.org/10.1016/B978-0-12-809633-8.20252-5

Lim XY; Pickford R; Don AS, 2016, 'Assaying ceramide synthase activity in vitro and in living cells using liquid chromatography-mass spectrometry', in Lipid Signaling Protocols, pp. 11 - 22, http://dx.doi.org/10.1007/978-1-4939-3170-5_2

Journal articles

Thoms JAI; Yan F; Hampton HR; Davidson S; Joshi S; Saw J; Sarowar CH; Lim XY; Nunez AC; Kakadia PM; Bhuyan GS; Zou X; Nguyen M; Ghodousi ES; Koch FC; Vafaee F; Thompson IR; Karimi MM; Pickford R; Raftery MJ; Hough S; Buckland G; Bailey M; Ghodke Y; Absar N; Vaughan L; Pasalic L; Fong CY; Kenealy M; Hiwase DK; Stoddart RI; Mohammed S; Lee L; Passam FH; Larsen SR; Spring KJ; Skarratt KK; Rebeiro P; Presgrave P; Stevenson WS; Ling S; Tiley C; Fuller SJ; Roncolato F; Enjeti AK; Hoenemann D; Lemech C; Jolly CJ; Bohlander SK; Curtis DJ; Wong JWH; Unnikrishnan A; Hertzberg M; Olivier J; Polizzotto MN; Pimanda JE, 2025, 'Clinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs', Nature Communications, 16, http://dx.doi.org/10.1038/s41467-025-59796-x

Isik FI; Fu YH; Pickford R; Cheng Q; Yang Y; Lewis SJG; Dzamko N; Halliday GM; Kim WS, 2025, 'Dysregulation of Monounsaturated Fatty Acids is Related to α-Synuclein in Multiple System Atrophy', Movement Disorders, 40, pp. 1940 - 1950, http://dx.doi.org/10.1002/mds.30248

Isik FI; Galper J; Pickford R; Dzamko N; Fu YH; Kim WS, 2025, 'Dysregulation of SELENOI Is Associated with TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis', Cells, 14, http://dx.doi.org/10.3390/cells14181457

Fu YH; Pickford R; Galper J; Phan K; Wu P; Li H; Kim YB; Dzamko N; Halliday GM; Kim WS, 2024, 'A protective role of ABCA5 in response to elevated sphingomyelin levels in Parkinson’s disease', Npj Parkinson S Disease, 10, http://dx.doi.org/10.1038/s41531-024-00632-2

Galper J; Mori G; McDonald G; Ahmadi Rastegar D; Pickford R; Lewis SJG; Halliday GM; Kim WS; Dzamko N, 2024, 'Prediction of motor and non-motor Parkinson’s disease symptoms using serum lipidomics and machine learning: a 2-year study', Npj Parkinson S Disease, 10, http://dx.doi.org/10.1038/s41531-024-00741-y

Toscan CE; McCalmont H; Ashoorzadeh A; Lin X; Fu Z; Doculara L; Kosasih HJ; Cadiz R; Zhou A; Williams S; Evans K; Khalili F; Cai R; Yeats KL; Gifford AJ; Pickford R; Mayoh C; Xie J; Henderson MJ; Trahair TN; Patterson AV; Smaill JB; de Bock CE; Lock RB, 2024, 'The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia', Blood Cancer Journal, 14, pp. 192, http://dx.doi.org/10.1038/s41408-024-01180-x

Thoms JAI; Yan F; Hampton HR; Davidson S; Joshi S; Saw J; Sarowar CH; Lim XY; Nunez AC; Kakadia PM; Bhuyan GS; Zou X; Nguyen M; Ghodousi ES; Koch FC; Vafaee F; Thompson R; Karimi MM; Pickford R; Raftery MJ; Hough S; Buckland G; Bailey M; Ghodke Y; Absar N; Vaughan L; Pasalic L; Fong CY; Kenealy M; Hiwase D; Stoddart R; Mohammed S; Lee L; Passam FH; Larsen SR; Spring KJ; Skarratt KK; Ling S; Stevenson WS; Presgrave P; Rebeiro P; Tiley C; Fuller S; Roncolato F; Enjeti K; Hoenemann D; Lemech C; Jolly CJ; Bohlander SK; Curtis DJ; Wong J; Unnikrishnan A; Enjeti AK; Hertzberg MS; Olivier J; Polizzotto MN; Pimanda JE, 2024, 'Clinical Response to Azacitidine in Myelodysplastic Neoplasms Is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor Cells In Vivo', BLOOD, 144, pp. 3223 - 3225, http://dx.doi.org/10.1182/blood-2024-201216

Bhardwaj S; Lee M; O'Carroll D; McDonald J; Osborne K; Khan S; Pickford R; Coleman N; O'Farrell C; Richards S; Manefield MJ, 2024, 'Biotransformation of 6:2/4:2 fluorotelomer alcohols by Dietzia aurantiaca J3: Enzymes and proteomics', Journal of Hazardous Materials, 478, http://dx.doi.org/10.1016/j.jhazmat.2024.135510

Lawson EF; Ghosh A; Grupen C; Netherton J; Aitken RJ; Smith ND; Lim R; Drury HR; Pickford R; Gibb Z; Baker M; Tanwar PS; Swegen A, 2024, 'Investigations into the role of platelet-activating factor in the peri-conception period of the mare', Reproduction Cambridge England, 168, http://dx.doi.org/10.1530/REP-24-0049

Sun J; Yu TT; Mirabediny M; Lee M; Jones A; O'Carroll DM; Manefield MJ; Kumar PV; Pickford R; Ramadhan ZR; Bhattacharyya SK; Åkermark B; Das B; Kumar N, 2024, 'Soluble metal porphyrins - Zero-valent zinc system for effective reductive defluorination of branched per and polyfluoroalkyl substances (PFASs)', Water Research, 258, http://dx.doi.org/10.1016/j.watres.2024.121803

Lawson EF; Pickford R; Aitken RJ; Gibb Z; Grupen CG; Swegen A, 2024, 'Mapping the lipidomic secretome of the early equine embryo', Frontiers in Veterinary Science, 11, http://dx.doi.org/10.3389/fvets.2024.1439550

Ackerman Grunfeld D; Jones AM; Sun J; Le ST; Pickford R; Huang Q; Manefield M; Kumar N; Lee MJ; O'Carroll DM, 2023, 'Electrochemical degradation of a C6-perfluoroalkyl substance (PFAS) using a simple activated carbon cathode', Environmental Science Water Research and Technology, 10, pp. 272 - 287, http://dx.doi.org/10.1039/d3ew00543g

Moles E; Howard CB; Huda P; Karsa M; McCalmont H; Kimpton K; Duly A; Chen Y; Huang Y; Tursky ML; Ma D; Bustamante S; Pickford R; Connerty P; Omari S; Jolly CJ; Joshi S; Shen S; Pimanda JE; Dolnikov A; Cheung LC; Kotecha RS; Norris MD; Haber M; de Bock CE; Somers K; Lock RB; Thurecht KJ; Kavallaris M; Moles Meler E, 2023, 'Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia', Science translational medicine, 15, pp. eabm1262 - eabm1262, http://dx.doi.org/10.1126/scitranslmed.abm1262

Abomughaid M; Tay ESE; Pickford R; Malladi C; Read SA; Coorssen JR; Gloss BS; George J; Douglas MW, 2023, 'PEMT Mediates Hepatitis C Virus-Induced Steatosis, Explains Genotype-Specific Phenotypes and Supports Virus Replication', International Journal of Molecular Sciences, 24, http://dx.doi.org/10.3390/ijms24108781

Shrestha GS; Vijay AK; Stapleton F; White A; Pickford R; Carnt N, 2023, 'Human tear metabolites associated with nucleoside-signalling pathways in bacterial keratitis', Experimental Eye Research, 228, pp. 109409, http://dx.doi.org/10.1016/j.exer.2023.109409

Phan K; He Y; Bhatia S; Pickford R; Mcdonald G; Mazumder S; Timmins HC; Hodges JR; Piguet O; Dzamko N; Halliday GM; Kiernan MC; Kim WS, 2023, 'Multiple pathways of lipid dysregulation in amyotrophic lateral sclerosis', Brain Communications, 5, http://dx.doi.org/10.1093/braincomms/fcac340

Fu YH; He Y; Phan K; Bhatia S; Pickford R; Wu P; Dzamko N; Halliday GM; Kim WS, 2022, 'Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain', Acta Neuropathologica Communications, 10, http://dx.doi.org/10.1186/s40478-022-01469-7

Pimanda JE; Thoms JAI; Hampton HR; Davidson S; Joshi S; Sarowar CH; Lim XY; Nunez AC; Kakadia PM; Pickford R; Raftery M; Hough S; Buckland G; Bailey M; Ghodke Y; Absar N; Vaughan L; Pasalic L; Fong CY; Kenealy M; Hiwase D; Stoddart R; Mohammed S; Lee L; Passam FH; Spring K; Skarratt KK; Rebeiro P; Larsen SR; Presgrave P; Stevenson WS; Ling S; Tiley C; Fuller S; Roncolato F; Enjeti AK; Hoenemann D; Lemech C; Bohlander SK; Olivier J; Hertzberg M; Unnikrishnan A; Polizzotto MN, 2022, 'In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial', Blood, 140, pp. 6927 - 6929, http://dx.doi.org/10.1182/blood-2022-157634

Dyer CEF; Clarke NE; Nguyen DN; Dilrukshi Herath HMP; Hii SF; Pickford R; Traub RJ; Nery SV, 2022, 'Assessing the efficacy of albendazole against hookworm in Vietnam using quantitative PCR and sodium nitrate flotation', Plos Neglected Tropical Diseases, 16, http://dx.doi.org/10.1371/journal.pntd.0010767

Galper J; Dean NJ; Pickford R; Lewis SJG; Halliday GM; Kim WS; Dzamko N, 2022, 'Lipid pathway dysfunction is prevalent in patients with Parkinson's disease', Brain, 145, pp. 3472 - 3487, http://dx.doi.org/10.1093/brain/awac176

Zheng Z; Deletic A; Toe CY; Amal R; Zhang X; Pickford R; Zhou S; Zhang K, 2022, 'Photo-electrochemical oxidation herbicides removal in stormwater: Degradation mechanism and pathway investigation', Journal of Hazardous Materials, 436, http://dx.doi.org/10.1016/j.jhazmat.2022.129239

Méndez V; Holland S; Bhardwaj S; McDonald J; Khan S; O'Carroll D; Pickford R; Richards S; O'Farrell C; Coleman N; Lee M; Manefield MJ; Mendez V, 2022, 'Aerobic biotransformation of 6:2 fluorotelomer sulfonate by Dietzia aurantiaca J3 under sulfur-limiting conditions', Science of the Total Environment, 829, pp. 154587, http://dx.doi.org/10.1016/j.scitotenv.2022.154587

Soeriyadi AH; Ongley SE; Kehr JC; Pickford R; Dittmann E; Neilan BA, 2022, 'Tailoring Enzyme Stringency Masks the Multispecificity of a Lyngbyatoxin (Indolactam Alkaloid) Nonribosomal Peptide Synthetase', Chembiochem, 23, http://dx.doi.org/10.1002/cbic.202100574

Fu Y; He Y; Phan K; Pickford R; Kim YB; Dzamko N; Halliday GM; Kim WS, 2022, 'Sex-specific lipid dysregulation in the Abca7 knockout mouse brain', Brain Communications, 4, http://dx.doi.org/10.1093/braincomms/fcac120

He Y; Phan K; Bhatia S; Pickford R; Fu YH; Yang Y; Hodges JR; Piguet O; Halliday GM; Kim WS, 2021, 'Increased VLCFA-lipids and ELOVL4 underlie neurodegeneration in frontotemporal dementia', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-00870-x

Yadav S; Pickford R; Zammit RA; Ballard JWO, 2021, 'Metabolomics shows the Australian dingo has a unique plasma profile', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-84411-6

Liu Y; Thalamuthu A; Mather KA; Crawford J; Ulanova M; Wong MWK; Pickford R; Sachdev PS; Braidy N, 2021, 'Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes', Translational Psychiatry, 11, http://dx.doi.org/10.1038/s41398-021-01362-2

Wotton A; Yeung T; Jennepalli S; Teh ZL; Pickford R; Huang S; Conibeer G; Stride JA; Patterson RJ, 2021, 'Simultaneous Fe3O4Nanoparticle Formation and Catalyst-Driven Hydrothermal Cellulose Degradation', ACS Omega, 6, pp. 10790 - 10800, http://dx.doi.org/10.1021/acsomega.1c00393

Soeriyadi AH; Mazmouz R; Pickford R; Al‐Sinawi B; Kellmann R; Pearson LA; Neilan BA, 2021, 'Cover Feature: Heterologous Expression of an Unusual Ketosynthase, SxtA, Leads to Production of Saxitoxin Intermediates in Escherichia coli (5/2021)', ChemBioChem, 22, pp. 762 - 762, http://dx.doi.org/10.1002/cbic.202100062

Soeriyadi AH; Mazmouz R; Pickford R; Al-Sinawi B; Kellmann R; Pearson LA; Neilan BA, 2021, 'Heterologous Expression of an Unusual Ketosynthase, SxtA, Leads to Production of Saxitoxin Intermediates in Escherichia coli', Chembiochem, 22, pp. 845 - 849, http://dx.doi.org/10.1002/cbic.202000675

Jonkhout N; Cruciani S; Santos Vieira HG; Tran J; Liu H; Liu G; Pickford R; Kaczorowski D; Franco GR; Vauti F; Camacho N; Abedini SS; Najmabadi H; Ribas de Pouplana L; Christ D; Schonrock N; Mattick JS; Novoa EM, 2021, 'Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation', RNA Biology, 18, pp. 1905 - 1919, http://dx.doi.org/10.1080/15476286.2021.1881291

Phan K; He Y; Pickford R; Bhatia S; Katzeff JS; Hodges JR; Piguet O; Halliday GM; Kim WS, 2020, 'Uncovering pathophysiological changes in frontotemporal dementia using serum lipids', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-60457-w

Liew G; Tse B; Ho IV; Joachim N; White A; Pickford R; Maltby D; Gopinath B; Mitchell P; Crossett B, 2020, 'Acylcarnitine abnormalities implicate mitochondrial dysfunction in patients with neovascular age-related macular degeneration', Investigative Ophthalmology and Visual Science, 61, http://dx.doi.org/10.1167/IOVS.61.8.32

Wong MWK; Thalamuthu A; Braidy N; Mather KA; Liu Y; Ciobanu L; Baune BT; Armstrong NJ; Kwok J; Schofield P; Wright MJ; Ames D; Pickford R; Lee T; Poljak A; Sachdev PS, 2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older australian twins', Elife, 9, pp. 1 - 28, http://dx.doi.org/10.7554/eLife.58954

Shimabukuro Okuda L; Tallada Iborra R; Ramos Pinto P; Fabres Machado U; Corrêa-Giannella ML; Pickford R; Woods T; Brimble MA; Rye KA; Passarelli M, 2020, 'Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages', Mediators of Inflammation, 2020, http://dx.doi.org/10.1155/2020/6515401

Liu Y; Chan DKY; Thalamuthu A; Wen W; Jiang J; Paradise M; Lee T; Crawford J; Wai Kin Wong M; Hua Xu Y; Poljak A; Pickford R; Sachdev PS; Braidy N; Xu Y-H, 2020, 'Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia', Computational and Structural Biotechnology Journal, 18, pp. 1613 - 1624, http://dx.doi.org/10.1016/j.csbj.2020.06.001

Stayte S; Laloli KJ; Rentsch P; Lowth A; Li KM; Pickford R; Vissel B, 2020, 'The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain', Experimental Neurology, 323, http://dx.doi.org/10.1016/j.expneurol.2019.113062

Coffey MJ; Nielsen S; Wemheuer B; Kaakoush NO; Garg M; Needham B; Pickford R; Jaffe A; Thomas T; Ooi CY, 2019, 'Gut Microbiota in Children With Cystic Fibrosis: A Taxonomic and Functional Dysbiosis', Scientific Reports, 9, pp. 18593, http://dx.doi.org/10.1038/s41598-019-55028-7

Tetu SG; Sarker I; Schrameyer V; Pickford R; Elbourne LDH; Moore LR; Paulsen IT, 2019, 'Plastic leachates impair growth and oxygen production in Prochlorococcus, the ocean’s most abundant photosynthetic bacteria', Communications Biology, 2, http://dx.doi.org/10.1038/s42003-019-0410-x

Wong MWK; Braidy N; Pickford R; Sachdev PS; Poljak A, 2019, 'Comparison of Single Phase and Biphasic Extraction Protocols for Lipidomic Studies Using Human Plasma', Frontiers in Neurology, 10, pp. 1 - 11, http://dx.doi.org/10.3389/fneur.2019.00879

Wong MWK; Braidy N; Pickford R; Vafaee F; Crawford J; Muenchhoff J; Schofield P; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI', Plos One, 14, pp. e0214141, http://dx.doi.org/10.1371/journal.pone.0214141

D'Agostino PM; Woodhouse JN; Liew HT; Sehnal L; Pickford R; Wong HL; Burns BP; Neilan BA, 2019, 'Bioinformatic, phylogenetic and chemical analysis of the UV-absorbing compounds scytonemin and mycosporine-like amino acids from the microbial mat communities of Shark Bay, Australia', Environmental Microbiology, 21, pp. 702 - 715, http://dx.doi.org/10.1111/1462-2920.14517

Wong MWK; Braidy N; Crawford J; Pickford R; Song F; Mather KA; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health', Journal of Alzheimer S Disease, 72, pp. 703 - 716, http://dx.doi.org/10.3233/JAD-190524

Atashrazm F; Hammond D; Perera G; Dobson-Stone C; Mueller N; Pickford R; Kim WS; Kwok JB; Lewis SJG; Halliday GM; Dzamko N, 2018, 'Reduced glucocerebrosidase activity in monocytes from patients with Parkinson’s disease', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-33921-x

Giardina M; Cheong S; Marjo CE; Clode PL; Guagliardo P; Pickford R; Pernice M; Seymour JR; Raina JB, 2018, 'Quantifying inorganic nitrogen assimilation by synechococcus using bulk and single-cell mass spectrometry: A comparative study', Frontiers in Microbiology, 9, pp. 2847, http://dx.doi.org/10.3389/fmicb.2018.02847

Cullen A; D'Agostino PM; Mazmouz R; Pickford R; Wood S; Neilan BA, 2018, 'Insertions within the Saxitoxin Biosynthetic Gene Cluster Result in Differential Toxin Profiles', ACS Chemical Biology, 13, pp. 3107 - 3114, http://dx.doi.org/10.1021/acschembio.8b00608

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