Select Publications
Journal articles
, 2025, 'Returning raw genomic data to research participants in a pediatric cancer precision medicine trial', Npj Genomic Medicine, 10, http://dx.doi.org/10.1038/s41525-025-00470-y
, 2025, 'Germline analysis of an international cohort of pediatric diffuse midline glioma patients', Neuro Oncology, 27, pp. 1849 - 1863, http://dx.doi.org/10.1093/neuonc/noaf061
, 2025, 'Psychosocial Outcomes in Parents of Children with Acute Lymphoblastic Leukaemia in Australia and New Zealand Through and Beyond Treatment', Cancers, 17, http://dx.doi.org/10.3390/cancers17071238
, 2025, 'Factors that influence the uptake of precision-guided treatment recommendations in paediatric cancer: a systematic review', British Journal of Cancer, http://dx.doi.org/10.1038/s41416-025-03171-6
, 2025, 'Pharmacogenomics in pediatric oncology: Australian adolescent or young adult and caregiver perspectives', Genetics in Medicine Open, 3, http://dx.doi.org/10.1016/j.gimo.2025.103452
, 2024, 'Second Opinion Seeking in Paediatric Oncology: Motivations and Predictors', Psycho Oncology, 33, http://dx.doi.org/10.1002/pon.70011
, 2024, 'Precision-guided treatment in high-risk pediatric cancers', Nature Medicine, 30, pp. 1913 - 1922, http://dx.doi.org/10.1038/s41591-024-03044-0
, 2024, 'Management of patients with diffuse intrinsic pontine glioma in Australia and New Zealand: Australian and New Zealand Children's Haematology/Oncology Group position statement', Medical Journal of Australia, 220, pp. 533 - 538, http://dx.doi.org/10.5694/mja2.52295
, 2024, 'Minimising Adverse Drug Reactions and Verifying Economic Legitimacy-Pharmacogenomics Implementation in Children (MARVEL- PIC): Protocol for a national randomised controlled trial of pharmacogenomics implementation', BMJ Open, 14, http://dx.doi.org/10.1136/bmjopen-2024-085115
, 2024, 'Down syndrome-associated leukaemias: current evidence and challenges', Therapeutic Advances in Hematology, 15, http://dx.doi.org/10.1177/20406207241257901
, 2023, 'A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer', Genome Medicine, 15, http://dx.doi.org/10.1186/s13073-023-01170-x
, 2023, 'Late effects in survivors of infant acute lymphoblastic leukaemia—a study of the Australian and New Zealand Children’s Haematology/Oncology Group', Blood Cancer Journal, 13, http://dx.doi.org/10.1038/s41408-023-00924-5
, 2023, 'Lessons learnt in the first year of an Australian pediatric cardio oncology clinic', Cardio Oncology, 9, http://dx.doi.org/10.1186/s40959-023-00194-x
, 2023, 'Hopes, concerns, satisfaction and regret in a precision medicine trial for childhood cancer: a mixed-methods study of parent and patient perspectives', British Journal of Cancer, 129, pp. 1634 - 1644, http://dx.doi.org/10.1038/s41416-023-02429-1
, 2023, 'Physician-defined severe toxicities occurring during and after cancer treatment: Modified consensus definitions and clinical applicability in the evaluation of cancer treatment', Frontiers in Pediatrics, 11, http://dx.doi.org/10.3389/fped.2023.1155449
, 2023, 'The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science', Neoplasia United States, 35, http://dx.doi.org/10.1016/j.neo.2022.100846
, 2022, 'Cardio-Oncology Recommendations for Pediatric Oncology Patients: An Australian and New Zealand Delphi Consensus', Jacc Advances, 1, http://dx.doi.org/10.1016/j.jacadv.2022.100155
, 2022, 'Prospective longitudinal evaluation of treatment-related toxicity and health-related quality of life during the first year of treatment for pediatric acute lymphoblastic leukemia', BMC Cancer, 22, pp. 985, http://dx.doi.org/10.1186/s12885-022-10072-x
, 2022, 'Acute central nervous system toxicity during treatment of pediatric acute lymphoblastic leukemia: phenotypes, risk factors and genotypes', Haematologica, 107, pp. 2318 - 2327, http://dx.doi.org/10.3324/haematol.2021.280016
, 2022, 'Developmental delay and progressive seizures in 2-month-old child with diffuse MRI abnormalities', Brain Pathology, 32, http://dx.doi.org/10.1111/bpa.13049
, 2022, 'Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia', Haematologica, 107, pp. 635 - 643, http://dx.doi.org/10.3324/haematol.2020.268565
, 2021, 'Severe toxicity free survival: physician-derived definitions of unacceptable long-term toxicities following acute lymphocytic leukaemia', Lancet Haematology, 8, pp. e513 - e523, http://dx.doi.org/10.1016/S2352-3026(21)00136-8
, 2021, 'A cost-effective approach to increasing participation in patient-reported outcomes research in cancer: A randomized trial of video invitations', International Journal of Cancer, 148, pp. 971 - 980, http://dx.doi.org/10.1002/ijc.33244
, 2021, 'The Australia and New Zealand Cardio-Oncology Registry: evaluation of chemotherapy-related cardiotoxicity in a national cohort of paediatric cancer patients', Internal Medicine Journal, 51, pp. 229 - 234, http://dx.doi.org/10.1111/imj.14719
, 2020, 'Genome-wide association meta-analysis of single-nucleotide polymorphisms and symptomatic venous thromboembolism during therapy for acute lymphoblastic leukemia and lymphoma in caucasian children', Cancers, 12, pp. 1285, http://dx.doi.org/10.3390/cancers12051285
, 2019, 'Risk factors for symptomatic venous thromboembolism during therapy for childhood acute lymphoblastic leukemia', Thrombosis Research, 178, pp. 132 - 138, http://dx.doi.org/10.1016/j.thromres.2019.04.011
, 2018, 'Health-related quality of life of survivors of childhood acute lymphoblastic leukemia: a systematic review', Quality of Life Research, 27, pp. 1431 - 1443, http://dx.doi.org/10.1007/s11136-018-1788-5
, 2017, 'Asparaginase-associated pancreatitis in childhood acute lymphoblastic leukaemia: an observational Ponte di Legno Toxicity Working Group study', Lancet Oncology, 18, pp. 1238 - 1248, http://dx.doi.org/10.1016/S1470-2045(17)30424-2
, 2017, 'Health-related quality of life of children on treatment for acute lymphoblastic leukemia: A systematic review', Pediatric Blood and Cancer, 64, http://dx.doi.org/10.1002/pbc.26489
, 2016, 'Asparaginase-Associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia: A Ponte Di Legno Toxicity Working Group Report on Clinical Presentation and Outcome', BLOOD, 128
, 2015, 'Down syndrome and leukemia: insights into leukemogenesis and translational targets', TRANSLATIONAL PEDIATRICS, 4, pp. 76 - 92, http://dx.doi.org/10.3978/j.issn.2224-4336.2015.03.03
, 2014, 'The prenatal origins of cancer', Nature Reviews Cancer, 14, pp. 277 - 289, http://dx.doi.org/10.1038/nrc3679
, 2013, 'Pharmacokinetic analysis of enoxaparin in a term neonate and review of literature', Thrombosis Research, 132, pp. 487 - 489, http://dx.doi.org/10.1016/j.thromres.2013.06.024
, 2013, 'Transplant-related mortality following allogeneic hematopoeitic stem cell transplantation for pediatric acute lymphoblastic leukemia: 25-year retrospective review', Pediatric Blood and Cancer, 60, pp. 1520 - 1527, http://dx.doi.org/10.1002/pbc.24559
Conference Papers
, 2011, 'IMPROVED SURVIVAL FOLLOWING ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) FOR PAEDIATRIC ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL): A RETROSPECTIVE REVIEW FROM 1984-2009', in PEDIATRIC BLOOD & CANCER, WILEY PERIODICALS, INC, pp. 817 - 817, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295239600446&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Abstracts
, 2024, 'Precision-guided treatment improves outcomes for children with high-risk cancers', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, Barcelona, Vol. 211, pp. S162 - S163, presented at 36th European-Organisation-for-Research-and-Treatment-of-Cancer / National-Cancer-Institute / American-Association-for-Cancer-Research Symposium on Molecular Targets and Cancer Therapeutics (EORTC/NCI/AACR), SPAIN, Barcelona, 23 October 2024 - 25 October 2024, http://dx.doi.org/10.1016/j.ejca.2024.114946
, 2024, 'Clinical utility of real-time comprehensive molecular profiling in childhood brain tumors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-B012
, 2024, 'Enhanced disease detection using single cell RNAseq in children with brain cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-A044
, 2024, 'Expanding therapeutic horizons: Unleashing the untapped potential of MEK inhibitor treatment in pediatric cancers', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-B003
, 2024, 'Implementing ultra-sensitive, ctDNA-based liquid biopsy for disease monitoring in paediatric tumours', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-A045
, 2024, 'NOVEL TRANSCRIPTS ASSOCIATE WITH SURVIVAL IN CHILDHOOD MEDULLOBLASTOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.513
, 2024, 'PEDIATRIC PATIENTS WITH DIFFUSE MIDLINE GLIOMA DEMONSTRATE AN UNEXPECTED PREVALENCE OF GERMLINE VARIANTS IN HOMOLOGOUS RECOMBINATION GENES', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.129
, 2021, 'Abstract 3044: The unexplored immune landscape of high-risk pediatric cancers', in Cancer Research, American Association for Cancer Research (AACR), Vol. 81, pp. 3044 - 3044, http://dx.doi.org/10.1158/1538-7445.am2021-3044
, 2021, 'The unexplored immune landscape of high-risk pediatric cancers.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, Vol. 81, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 10 April 2021 - 21 May 2021
, 2017, 'Clinical and Germline Risk Factors for the Occurrence of Multiple Treatment Toxicities during Childhood Acute Lymphoblastic Leukemia (ALL) Therapy', in BLOOD, AMER SOC HEMATOLOGY, GA, Atlanta, Vol. 130, presented at 59th Annual Meeting of the American-Society-of-Hematology (ASH), GA, Atlanta, 09 December 2017 - 12 December 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432419405157&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2016, 'Clinical Predictors of Venous Thromboembolism during Therapy for Childhood Acute Lymphoblastic Leukemia', in BLOOD, AMER SOC HEMATOLOGY, CA, San Diego, Vol. 128, presented at 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), CA, San Diego, 03 December 2016 - 06 December 2016, http://dx.doi.org/10.1182/blood.V128.22.1182.1182
, 2015, 'Age Adjusted Telomere Length Decreases Following Treatment for Pediatric Acute Lymphoblastic Leukemia, but Does Not Predict Toxicity', in BLOOD, AMER SOC HEMATOLOGY, FL, Orlando, Vol. 126, presented at 57th Annual Meeting of the American-Society-of-Hematology, FL, Orlando, 05 December 2015 - 08 December 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368021803287&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Preprints
, 2024, Integrated germline and somatic molecular profiling to detect cancer predisposition has a high clinical impact in poor-prognosis paediatric cancer, http://dx.doi.org/10.1101/2024.08.08.24311493
, 2023, Lessons Learnt in the First Year of an Australian Pediatric Cardio Oncology Clinic, http://dx.doi.org/10.21203/rs.3.rs-3281090/v1
, 2023, Precision-guided treatment improves outcomes for children with high-risk cancers, http://dx.doi.org/10.21203/rs.3.rs-3376668/v1