By Dr Khawar Sohail Siddiqui

Journal articles

Clarke RA; Govindaraju H; Beretta M; Olzomer E; Lawther AJ; Walker AK; Fang Z; Eapen V; Hyams TC; Killingsworth M; Bridge W; Turner N; Siddiqui KS; Cohen Hyams T, 2024, 'Immp2l Enhances the Structure and Function of Mitochondrial Gpd2 Dehydrogenase', International Journal of Molecular Sciences, 25, pp. 990, http://dx.doi.org/10.3390/ijms25020990

Lawther AJ; Zieba J; Fang Z; Furlong TM; Conn I; Govindaraju H; Choong LLY; Turner N; Siddiqui KS; Bridge W; Merlin S; Hyams TC; Killingsworth M; Eapen V; Clarke RA; Walker AK; Cohen Hyams T, 2023, 'Antioxidant Behavioural Phenotype in the Immp2l Gene Knock-Out Mouse', Genes, 14, pp. 1717, http://dx.doi.org/10.3390/genes14091717

Hoque MZ; Alqahtani A; Sankaran S; Anand D; Musa MM; Nzila A; Guerriero G; Siddiqui KS; Ahmad I, 2023, 'Corrigendum: Enhanced biodegradation of phenanthrene and anthracene using a microalgal-bacterial consortium (Frontiers in Microbiology, (2023), 14, (1227210), 10.3389/fmicb.2023.1227210)', Frontiers in Microbiology, 14, http://dx.doi.org/10.3389/fmicb.2023.1303835

Hoque MZ; Sankaran S; Anand D; Musa MM; Nzila A; Guerriero G; Siddiqui KS; Ahmad I, 2023, 'Enhanced biodegradation of phenanthrene and anthracene using a microalgal-bacterial consortium', Frontiers in Microbiology, 14, pp. 1227210, http://dx.doi.org/10.3389/fmicb.2023.1227210

Siddiqui KS; Poljak A; Ertan H; Bridge W, 2022, 'The use of isothermal titration calorimetry for the assay of enzyme activity: Application in higher education practical classes', Biochemistry and Molecular Biology Education, 50, pp. 519 - 526, http://dx.doi.org/10.1002/bmb.21657

Siddiqui KS; Ertan H; Poljak A; Bridge WJ, 2022, 'Evaluating Enzymatic Productivity—The Missing Link to Enzyme Utility', International Journal of Molecular Sciences, 23, pp. 1 - 16, http://dx.doi.org/10.3390/ijms23136908

Shah SS; Qasem MAA; Berni R; Del Casino C; Cai G; Contal S; Ahmad I; Siddiqui KS; Gatti E; Predieri S; Hausman JF; Cambier S; Guerriero G; Aziz MA, 2021, 'Physico-chemical properties and toxicological effects on plant and algal models of carbon nanosheets from a nettle fibre clone', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-86426-5

Ang DL; Hoque MZ; Hossain MA; Guerriero G; Berni R; Hausman JF; Bokhari SA; Bridge WJ; Siddiqui KS, 2021, 'Computational analysis of thermal adaptation in extremophilic chitinases: The achilles’ heel in protein structure and industrial utilization', Molecules, 26, http://dx.doi.org/10.3390/molecules26030707

Mushtaq U; Bhat SS; Parray AA; Nabi S; Wani AH; Qurashi AH; Siddiqui KS; Khanday FA, 2021, 'A simple, economical and environmental-friendly method for staining protein gels using an extract from walnut-husk', Chemico Biological Interactions, 333, http://dx.doi.org/10.1016/j.cbi.2020.109310

Berni R; Piasecki E; Legay S; Hausman JF; Siddiqui KS; Cai G; Guerriero G, 2019, 'Identification of the laccase-like multicopper oxidase gene family of sweet cherry (Prunus avium L.) and expression analysis in six ancient Tuscan varieties', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-39151-z

Guerriero G; Deshmukh R; Sonah H; Sergeant K; Hausman JF; Lentzen E; Valle N; Siddiqui KS; Exley C, 2019, 'Identification of the aquaporin gene family in Cannabis sativa and evidence for the accumulation of silicon in its tissues', Plant Science, 287, http://dx.doi.org/10.1016/j.plantsci.2019.110167

Shemsi AM; Khanday FA; Qurashi A; Khalil A; Guerriero G; Siddiqui KS, 2019, 'Site-directed chemically-modified magnetic enzymes: fabrication, improvements, biotechnological applications and future prospects', Biotechnology Advances, 37, pp. 357 - 381, http://dx.doi.org/10.1016/j.biotechadv.2019.02.002

Berni R; Hoque MZ; Legay S; Cai G; Siddiqui KS; Hausman JF; Andre CM; Guerriero G, 2019, 'Tuscan varieties of sweet cherry are rich sources of ursolic and oleanolic acid: Protein modeling coupled to targeted gene expression and metabolite analyses', Molecules, 24, http://dx.doi.org/10.3390/molecules24081590

Saqib AAN; Siddiqui KS, 2018, 'How to calculate thermostability of enzymes using a simple approach', Biochemistry and Molecular Biology Education, 46, pp. 398 - 402, http://dx.doi.org/10.1002/bmb.21127

Guerriero G; Berni R; Muñoz-Sanchez JA; Apone F; Abdel-Salam EM; Qahtan AA; Alatar AA; Cantini C; Cai G; Hausman JF; Siddiqui KS; Hernández-Sotomayor SMT; Faisal M, 2018, 'Production of plant secondary metabolites: Examples, tips and suggestions for biotechnologists', Genes, 9, http://dx.doi.org/10.3390/genes9060309

Guerriero G; Sergeant K; Legay S; Hausman JF; Cauchie HM; Ahmad I; Siddiqui KS, 2018, 'Novel insights from comparative in silico analysis of green microalgal cellulases', International Journal of Molecular Sciences, 19, pp. 1782, http://dx.doi.org/10.3390/ijms19061782

Khan I; Khalil A; Khanday F; Shemsi AM; Qurashi A; Siddiqui KS, 2018, 'Synthesis, Characterization and Applications of Magnetic Iron Oxide Nanostructures', Arabian Journal for Science and Engineering, 43, pp. 43 - 61, http://dx.doi.org/10.1007/s13369-017-2835-1

Guerriero G; Mangeot-Peter L; Legay S; Behr M; Lutts S; Siddiqui KS; Hausman JF, 2017, 'Identification of fasciclin-like arabinogalactan proteins in textile hemp (Cannabis sativa L.): In silico analyses and gene expression patterns in different tissues', BMC Genomics, 18, http://dx.doi.org/10.1186/s12864-017-3970-5

Jayawardena MB; Yee LH; Poljak A; Cavicchioli R; Kjelleberg SJ; Siddiqui KS, 2017, 'Enhancement of lipase stability and productivity through chemical modification and its application to latex-based polymer emulsions', Process Biochemistry, 57, pp. 131 - 140, http://dx.doi.org/10.1016/j.procbio.2017.03.014

Siddiqui KS, 2017, 'Defying the activity–stability trade-off in enzymes: taking advantage of entropy to enhance activity and thermostability', Critical Reviews in Biotechnology, 37, pp. 309 - 322, http://dx.doi.org/10.3109/07388551.2016.1144045

Taha ; Siddiqui KS; Campanaro S; Najnin T; Deshpande N; Williams TJ; Aldrich-Wright J; Wilkins M; Curmi PMG; Cavicchioli R, 2016, 'Single TRAM domain RNA-binding proteins in Archaea: functional insight from Ctr3 from the Antarctic methanogen Methanococcoides burtonii', Environmental Microbiology, 18, pp. 2810 - 2824, http://dx.doi.org/10.1111/1462-2920.13229

Najnin T; Siddiqui KS; Taha ; Elkaid N; Kornfeld G; Curmi PMG; Cavicchioli R, 2016, 'Erratum: Characterization of a temperature-responsive two component regulatory system from the Antarctic archaeon, Methanococcoides burtonii (Scientific Reports (2016) 6 (24278) DOI: 10.1038/srep24278)', Scientific Reports, 6, pp. 27162, http://dx.doi.org/10.1038/srep27162

Najnin T; Siddiqui KS; Taha ; Elkaid N; Kornfeld G; Curmi PMG; Cavicchioli R, 2016, 'Characterization of a temperature-responsive two component regulatory system from the Antarctic archaeon, Methanococcoides burtonii', Scientific Reports, 6, pp. 24278, http://dx.doi.org/10.1038/srep24278

Guerriero G; Hausman JF; Strauss J; Ertan H; Siddiqui KS, 2016, 'Lignocellulosic biomass: Biosynthesis, degradation, and industrial utilization', Engineering in Life Sciences, 16, pp. 1 - 16, http://dx.doi.org/10.1002/elsc.201400196

Guerriero G; Hausman JF; Strauss J; Ertan H; Siddiqui KS, 2015, 'Destructuring plant biomass: Focus on fungal and extremophilic cell wall hydrolases', Plant Science, 234, pp. 180 - 193, http://dx.doi.org/10.1016/j.plantsci.2015.02.010

Ertan H; Cassel C; Verma A; Poljak A; Charlton T; Aldrich-Wright J; Omar SM; Siddiqui KS; Cavicchioli R, 2015, 'A new broad specificity alkaline metalloprotease from a Pseudomonas sp. isolated from refrigerated milk: Role of calcium in improving enzyme productivity', Journal of Molecular Catalysis B Enzymatic, 113, pp. 1 - 8, http://dx.doi.org/10.1016/j.molcatb.2014.12.010

Siddiqui KS, 2015, 'Some like it hot, some like it cold: Temperature dependent biotechnological applications and improvements in extremophilic enzymes', Biotechnology Advances, 33, pp. 1912 - 1922, http://dx.doi.org/10.1016/j.biotechadv.2015.11.001

Das T; Sehar S; Koop L; Wong YK; Ahmed S; Siddiqui KS; Manefield M, 2014, 'Influence of calcium in extracellular DNA mediated bacterial aggregation and biofilm formation', Plos One, 9, http://dx.doi.org/10.1371/journal.pone.0091935

Siddiqui KS; Ertan H; Charlton T; Poljakc A; Khaled AK; Yang X; Marshall G; Cavicchioli R; Poljak A, 2014, 'Versatile peroxidase degradation of humic substances: Use of isothermal titration calorimetry to assess kinetics, and applications to industrial wastes', Journal of Biotechnology, 178, pp. 1 - 11, http://dx.doi.org/10.1016/j.jbiotec.2014.03.002

Muenchhoff J; Siddiqui KS; Neilan BA, 2012, 'Identification of two residues essential for the stringent substrate specificity and active site stability of the prokaryotic l -arginine:glycine amidinotransferase CyrA', FEBS Journal, 279, pp. 805 - 815, http://dx.doi.org/10.1111/j.1742-4658.2012.08472.x

Muenchhoff J; Siddiqui KS; Poljak A; Raftery MJ; Barrow KD; Neilan BA, 2010, 'A novel prokaryotic L-arginine:glycine amidinotransferase is involved in cylindrospermopsin biosynthesis', FEBS Journal, 277, pp. 3844 - 3860

Siddiqui KS; Parkin DM; Curmi PM; De Francisci D; Poljak A; Barrow KD; Noble M; Trewhella J; Cavicchioli R, 2009, 'A novel approach for enhancing the catalytic efficiency of a protease at low temperature: Reduction in substrate inhibition by chemical modification', Biotechnology and Bioengineering, 103, pp. 676 - 686

Allen MA; Lauro FM; Williams TJ; Burg DW; Siddiqui KS; De Francisci D; Chong K; Pilak O; Chew H; De Maere M; Ting LL; Katrib M; Ng SC; Sowers KR; Galperin M; Anderson I; Ivanova N; Dalin E; Martinez MP; Lapidus A; Hauser L; Land MH; Thomas T; Cavicchioli R, 2009, 'The genome sequence of the psychrophilic archaeon, Methanococcoides burtonii: The role of genome evolution in cold adaptation', ISME Journal, 3, pp. 1012 - 1035

Afzal AJ; Bokhari SA; Siddiqui KS, 2008, 'Erratum: Kinetic and thermodynamic study of a chemically modified highly active xylanase from scopulariopsis sp (Applied Biochemistry and Biotechnology))', Applied Biochemistry and Biotechnology, 150, pp. 113, http://dx.doi.org/10.1007/s12010-008-8157-8

Afzal AJ; Bokhari SA; Siddiqui KS, 2007, 'Kinetic and thermodynamic study of a chemically modified highly active xylanase from Scopulariopsis sp.', Applied Biochemistry and Biotechnology, 141, pp. 273 - 297, http://dx.doi.org/10.1007/BF02729068

Afzal A; Bokhari S; Siddiqui KS, 2007, 'Kinetic and thermodynamic study of a chemically modified highly active xylanase from Scopulariopsis sp - Existence of an essential amino group', Applied Biochemistry and Biotechnology, 141, pp. 273 - 297

Giaquinto L; Curmi PM; Siddiqui KS; Poljak A; DeLong E; DasSarma S; Cavicchioli R, 2007, 'Structure and function of cold shock proteins in archaea', Journal of Bacteriology, 189, pp. 5738 - 5748

Siddiqui KS; Cavicchioli R, 2006, 'Cold-adapted enzymes', Annual Review of Biochemistry, 75, pp. 403 - 433

Siddiqui KS; Poljak A; Guilhaus M; De Francisci D; Curmi PM; Feller G; D Amico S; Gerday C; Uversky V; Cavicchioli R, 2006, 'Role of lysine versus arginine in enzyme cold-adaptation: Modifying lysine to homo-arginine stabilizes the cold-adapted alpha-amylase from Pseudoalteramonas haloplanktis', Proteins - Structure Function and Bioinformatics, 64, pp. 486 - 501

Siddiqui KS; Cavicchioli R, 2005, 'Improved thermal stability and activity in the cold-adapted lipase B from Candida antarctica following chemical modification with oxidized polysaccharides', Extremophiles, 9, pp. 471 - 476

Afzal A; Ali S; Latif F; Rajoka M; Siddiqui KS, 2005, 'Innovative kinetic and thermodynamic analysis of a purified superactivexylanase from Scopulariopsis sp', Applied Biochemistry and Biotechnology, 120, pp. 51 - 70

Siddiqui KS; Poljak A; Guilhaus M; Feller G; D Amico S; Gerday C; Cavicchioli R, 2005, 'Role of disulfide bridges in the activity and stability of a cold-active alpha-amylase', Journal of Bacteriology, 187, pp. 6206 - 6212

Siddiqui KS; Feller G; D Amico S; Gerday C; Giaquinto L; Cavicchioli R, 2005, 'The active site is the least stable structure in the unfolding pathway of a multidomain cold-adapted alpha-amylase', Journal of Bacteriology, 187, pp. 6197 - 6205

Siddiqui KS; Bokhari S; Afzal A; Singh S, 2004, 'A novel thermodynamic relationship based on Kramers Theory for study ingenzyme kinetics under high viscosity', IUBMB Life, 56, pp. 403 - 407

Siddiqui KS; Poljak A; Cavicchioli R, 2004, 'Improved activity and stability of alkaline phosphatases from psychrophilic and mesophilic organisms by chemically modifying aliphatic or amino groups using tetracarboxy-benzophenone derivatives', Cellular and Molecular Biology, 50, pp. 657 - 667

Bokhari SA; Afzal AJ; Rashid MH; Rajoka MI; Siddiqui KS, 2002, 'Coupling of surface carboxyls of carboxymethylcellulase with aniline via chemical modification: Extreme thermostabilization in aqueous and water-miscible organic mixtures', Biotechnology Progress, 18, pp. 276 - 281, http://dx.doi.org/10.1021/bp010146h

Cavicchioli R; Sowers KR; Siddiqui KS; Andrews D, 2002, 'Low-temperature extremophiles and their applications', Current Opinion in Biotechnology, 13, pp. 253 - 261

Siddiqui KS; Cavicchioli R; Thomas T, 2002, 'Thermodynamic activation properties of elongation factor 2 (EF-2) proteins from psychrotolerant and thermophilic Archaea', Extremophiles, 6, pp. 143 - 150

Siddiqui KS; Saqib AAN; Rashid MH; Rajoka MI, 2000, 'Carboxyl group modification significantly altered the kinetic properties of purified carboxymethylcellulase from Aspergillus niger', Enzyme and Microbial Technology, 27, pp. 467 - 474, http://dx.doi.org/10.1016/S0141-0229(00)00254-4

Afzal AJ; Bokhari SA; Ahmad W; Rashid MH; Rajoka MI; Siddiqui KS, 2000, 'Two simple and rapid methods for the detection of polymer-degrading enzymes on high-resolution, alkaline, cold, in situ-native (HiRACIN)-PAGE and high-resolution, in situ-inhibited native (HiRISIN)-PAGE', Biotechnology Letters, 22, pp. 957 - 960, http://dx.doi.org/10.1023/A:1005676824462

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