By Dr Jason Ciril Kovacic

Journal articles

Iismaa SE; Hesselson S; McGrath-Cadell L; Muller DW; Fatkin D; Giannoulatou E; Kovacic J; Graham RM, 2021, 'Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia: Vasculopathies With a Predilection for Women', Heart Lung and Circulation, 30, pp. 27 - 35, http://dx.doi.org/10.1016/j.hlc.2020.05.110

Bax M; Junday K; Hesselson S; Iismaa S; Tarr I; McGrath-Cadell L; Dunwoodie S; Fatkin D; Kovacic J; Muller D; Giannoulatou E; Graham R, 2021, 'Modelling Spontaneous Coronary Artery Dissection With iPSC-Derived Vascular Cells', Heart, Lung and Circulation, 30, pp. S131 - S131, http://dx.doi.org/10.1016/j.hlc.2021.06.089

McGrath-Cadell L; Iismaa SE; Hesselson S; Muller DW; Fatkin D; Giannoulatou E; Kovacic JC; Graham RM, 2021, 'Recent Updates on Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia', International Journal of Integrative Cardiology, 3, http://dx.doi.org/10.47275/2690-862x-121

McGrath-Cadell L; Hesselson S; Tarr I; Iismaa S; Bax M; Junday K; Dunwoodie S; Fatkin D; Kovacic J; Muller D; Giannoulatou E; Graham B, 2021, 'Spontaneous Coronary Artery Dissection (SCAD) and a Family History of Aortic Artery Dissection—A Case Series', Heart, Lung and Circulation, 30, pp. S252 - S252, http://dx.doi.org/10.1016/j.hlc.2021.06.350

Beyhoff N; Cao D; Mehran R; Dangas G; Baber U; Sartori S; Blum M; Roumeliotis A; Chandiramani R; Goel R; Zhang Z; Kovacic J; Krishnan P; Barman N; Kapur V; Sweeny J; Sharma SK; Kini A, 2020, 'Prognostic Impact of High-Sensitivity C-Reactive Protein in Patients Undergoing Percutaneous Coronary Intervention According to BMI', Jacc Cardiovascular Interventions, 13, pp. 2882 - 2892, http://dx.doi.org/10.1016/j.jcin.2020.09.024

Trivieri MG; Spagnolo P; Birnie D; Liu P; Drake W; Kovacic JC; Baughman R; Fayad ZA; Judson MA, 2020, 'Challenges in Cardiac and Pulmonary Sarcoidosis: JACC State-of-the-Art Review', Journal of the American College of Cardiology, 76, pp. 1878 - 1901, http://dx.doi.org/10.1016/j.jacc.2020.08.042

Ma L; Chandel N; Ermel R; Sukhavasi K; Hao K; Ruusalepp A; Björkegren JLM; Kovacic JC, 2020, 'Multiple independent mechanisms link gene polymorphisms in the region of ZEB2 with risk of coronary artery disease', Atherosclerosis, 311, pp. 20 - 29, http://dx.doi.org/10.1016/j.atherosclerosis.2020.08.013

Aoi S; Baber U; Kovacic JC; Mehran R; Aquino M; Dangas G; Sweeny J; Vijay P; Shah S; Barman N; Moreno P; Kini AS; Sharma SK, 2020, 'Combined and independent impact of coronary artery calcification and inflammation on risk for adverse cardiovascular events after percutaneous coronary intervention: Results from a large single-center registry', Catheterization and Cardiovascular Interventions, 96, pp. E278 - E286, http://dx.doi.org/10.1002/ccd.28784

Plitt A; Claessen BE; Sartori S; Baber U; Chandrasekhar J; Aquino M; Vijay P; Elsayed S; Kovacic JC; Sweeny J; Barman N; Moreno P; Krishnan P; Demopoulos A; Dangas G; Kini AS; Mehran R; Sharma SK, 2020, 'Impact of stent diameter on outcomes following percutaneous coronary intervention with second-generation drug-eluting stents: Results from a large single-center registry', Catheterization and Cardiovascular Interventions, 96, pp. 558 - 564, http://dx.doi.org/10.1002/ccd.28488

Chandrasekhar J; Dangas G; Baber U; Sartori S; Qadeer A; Aquino M; Vogel B; Faggioni M; Vijay P; Claessen BE; Goel R; Moreno P; Krishnan P; Kovacic JC; Kini A; Mehran R; Sharma S, 2020, 'Impact of insulin treated and non-insulin-treated diabetes compared to patients without diabetes on 1-year outcomes following contemporary PCI', Catheterization and Cardiovascular Interventions, 96, pp. 298 - 308, http://dx.doi.org/10.1002/ccd.28841

Tang GHL; Lerakis S; Kini A; Khan JM; Kovacic JC, 2020, '4-Dimensional Transesophageal Echocardiographic Guidance During TAVR With BASILICA', Jacc Cardiovascular Imaging, 13, pp. 1601 - 1614, http://dx.doi.org/10.1016/j.jcmg.2019.11.022

Tang GHL; Zaid S; Fuchs A; Yamabe T; Yazdchi F; Gupta E; Ahmad H; Kofoed KF; Goldberg JB; Undemir C; Kaple RK; Shah PB; Kaneko T; Lansman SL; Khera S; Kovacic JC; Dangas GD; Lerakis S; Sharma SK; Kini A; Adams DH; Khalique OK; Hahn RT; Søndergaard L; George I; Kodali SK; De Backer O; Leon MB; Bapat VN, 2020, 'Alignment of Transcatheter Aortic-Valve Neo-Commissures (ALIGN TAVR): Impact on Final Valve Orientation and Coronary Artery Overlap', Jacc Cardiovascular Interventions, 13, pp. 1030 - 1042, http://dx.doi.org/10.1016/j.jcin.2020.02.005

del Monte-Nieto G; Fischer JW; Gorski DJ; Harvey RP; Kovacic JC, 2020, 'Basic Biology of Extracellular Matrix in the Cardiovascular System, Part 1/4: JACC Focus Seminar', Journal of the American College of Cardiology, 75, pp. 2169 - 2188, http://dx.doi.org/10.1016/j.jacc.2020.03.024

Frangogiannis NG; Kovacic JC, 2020, 'Extracellular Matrix in Ischemic Heart Disease, Part 4/4: JACC Focus Seminar', Journal of the American College of Cardiology, 75, pp. 2219 - 2235, http://dx.doi.org/10.1016/j.jacc.2020.03.020

Barallobre-Barreiro J; Loeys B; Mayr M; Rienks M; Verstraeten A; Kovacic JC, 2020, 'Extracellular Matrix in Vascular Disease, Part 2/4: JACC Focus Seminar', Journal of the American College of Cardiology, 75, pp. 2189 - 2203, http://dx.doi.org/10.1016/j.jacc.2020.03.018

Díez J; González A; Kovacic JC, 2020, 'Myocardial Interstitial Fibrosis in Nonischemic Heart Disease, Part 3/4: JACC Focus Seminar', Journal of the American College of Cardiology, 75, pp. 2204 - 2218, http://dx.doi.org/10.1016/j.jacc.2020.03.019

Zaid S; Sengupta A; Okoli K; Tsoi M; Khan A; Ahmad H; Goldberg JB; Undemir C; Rozenshtein A; Patel N; Khan M; Gupta E; Kovacic J; Lansman SL; Dangas GD; Sharma SK; Kini A; Tang GHL, 2020, 'Novel Anatomic Predictors of New Persistent Left Bundle Branch Block After Evolut Transcatheter Aortic Valve Implantation', American Journal of Cardiology, 125, pp. 1222 - 1229, http://dx.doi.org/10.1016/j.amjcard.2020.01.008

Santini MP; Malide D; Hoffman G; Pandey G; D'Escamard V; Nomura-Kitabayashi A; Rovira I; Kataoka H; Ochando J; Harvey RP; Finkel T; Kovacic JC, 2020, 'Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner', Cell Reports, 30, pp. 555 - 570.e7, http://dx.doi.org/10.1016/j.celrep.2019.12.045

Fernandez-Jimenez R; Jaslow R; Bansilal S; Diaz-Munoz R; Fatterpekar M; Santana M; Clarke-Littman A; Latina J; Soto AV; Hill CA; Al-Kazaz M; Samtani R; Vedanthan R; Giannarelli C; Kovacic JC; Bagiella E; Kasarskis A; Fayad ZA; Fuster V, 2020, 'Different Lifestyle Interventions in Adults From Underserved Communities: The FAMILIA Trial', Journal of the American College of Cardiology, 75, pp. 42 - 56, http://dx.doi.org/10.1016/j.jacc.2019.10.021

Olin JW; Di Narzo AF; D'Escamard V; Kadian-Dodov D; Cheng H; Georges A; King A; Thomas A; Barwari T; Michelis KC; Bouchareb R; Bander E; Anyanwu A; Stelzer P; Filsoufi F; Florman S; Civelek M; Debette S; Jeunemaitre X; Björkegren JLM; Mayr M; Bouatia-Naji N; Hao K; Kovacic JC, 2020, 'A plasma proteogenomic signature for fibromuscular dysplasia', Cardiovascular Research, 116, pp. 63 - 77, http://dx.doi.org/10.1093/cvr/cvz219

Sengupta A; Alexis SL; Kovacic JC; Tang GHL, 2020, 'Current challenges in TAVI: Neo-commissural alignment to mimic more physiologic valve implantation', Vessel Plus, 4, http://dx.doi.org/10.20517/2574-1209.2020.55

Haider N; Boscá L; Zandbergen HR; Kovacic JC; Narula N; González-Ramos S; Fernandez-Velasco M; Agrawal S; Paz-García M; Gupta S; DeLeon-Pennell K; Fuster V; Ibañez B; Narula J, 2019, 'Transition of Macrophages to Fibroblast-Like Cells in Healing Myocardial Infarction', Journal of the American College of Cardiology, 74, pp. 3124 - 3135, http://dx.doi.org/10.1016/j.jacc.2019.10.036

Fatkin D; Huttner IG; Kovacic JC; Seidman JG; Seidman CE, 2019, 'Precision Medicine in the Management of Dilated Cardiomyopathy: JACC State-of-the-Art Review', Journal of the American College of Cardiology, 74, pp. 2921 - 2938, http://dx.doi.org/10.1016/j.jacc.2019.10.011

Glicksberg BS; Amadori L; Akers NK; Sukhavasi K; Franzén O; Li L; Belbin GM; Ayers KL; Shameer K; Badgeley MA; Johnson KW; Readhead B; Darrow BJ; Kenny EE; Betsholtz C; Ermel R; Skogsberg J; Ruusalepp A; Schadt EE; Dudley JT; Ren H; Kovacic JC; Giannarelli C; Li SD; Björkegren JLM; Chen R, 2019, 'Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits (BMC Medical Genomics DOI: 10.1186/s12920-019-0542-3)', BMC Medical Genomics, 12, http://dx.doi.org/10.1186/s12920-019-0573-9

Hulshoff MS; Del Monte-Nieto G; Kovacic J; Krenning G, 2019, 'Non-coding RNA in endothelial-to-mesenchymal transition', Cardiovascular Research, 115, pp. 1716 - 1731, http://dx.doi.org/10.1093/cvr/cvz211

Tadros RO; Tang GHL; Barnes HJ; Mousavi I; Kovacic JC; Faries P; Olin JW; Marin ML; Adams DH, 2019, 'Optimal Treatment of Uncomplicated Type B Aortic Dissection: JACC Review Topic of the Week', Journal of the American College of Cardiology, 74, pp. 1494 - 1504, http://dx.doi.org/10.1016/j.jacc.2019.07.063

Glicksberg BS; Amadori L; Akers NK; Sukhavasi K; Franzén O; Li L; Belbin GM; Akers KL; Shameer K; Badgeley MA; Johnson KW; Readhead B; Darrow BJ; Kenny EE; Betsholtz C; Ermel R; Skogsberg J; Ruusalepp A; Schadt EE; Dudley JT; Ren H; Kovacic JC; Giannarelli C; Li SD; Björkegren JLM; Chen R, 2019, 'Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits', BMC Medical Genomics, 12, http://dx.doi.org/10.1186/s12920-019-0542-3

Guedeney P; Claessen BE; Kalkman DN; Aquino M; Sorrentino S; Giustino G; Farhan S; Vogel B; Sartori S; Montalescot G; Sweeny J; Kovacic JC; Krishnan P; Barman N; Dangas G; Kini A; Baber U; Sharma S; Mehran R, 2019, 'Residual Inflammatory Risk in Patients With Low LDL Cholesterol Levels Undergoing Percutaneous Coronary Intervention (vol 73, pg 2401, 2019)', JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 74, pp. 481 - 482, http://dx.doi.org/10.1016/j.jacc.2019.06.009

Tang GHL; Zaid S; Gupta E; Ahmad H; Khan A; Kovacic JC; Lansman SL; Dangas GD; Sharma SK; Kini A, 2019, 'Feasibility of Repeat TAVR After SAPIEN 3 TAVR: A Novel Classification Scheme and Pilot Angiographic Study', Jacc Cardiovascular Interventions, 12, pp. 1290 - 1292, http://dx.doi.org/10.1016/j.jcin.2019.02.020

Tang GHL; Zaid S; Gupta E; Ahmad H; Patel N; Khan M; Khan A; Kovacic JC; Lansman SL; Dangas GD; Sharma SK; Kini A, 2019, 'Impact of Initial Evolut Transcatheter Aortic Valve Replacement Deployment Orientation on Final Valve Orientation and Coronary Reaccess: A Pilot Study', Circulation Cardiovascular Interventions, 12, http://dx.doi.org/10.1161/CIRCINTERVENTIONS.119.008044

Zeng L; Talukdar HA; Koplev S; Giannarelli C; Ivert T; Gan LM; Ruusalepp A; Schadt EE; Kovacic JC; Lusis AJ; Michoel T; Schunkert H; Björkegren JLM, 2019, 'Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease', Journal of the American College of Cardiology, 73, pp. 2946 - 2957, http://dx.doi.org/10.1016/j.jacc.2019.03.520

Mahajan AM; Claessen BE; Chandrasekhar J; Sartori S; Aquino M; Baber U; Dangas G; Kovacic JC; Krishnan P; Moreno P; Sweeny J; Barman N; Vijay P; Kini A; Mehran R; Sharma S, 2019, 'Outcomes by Gender and Ethnicity After Percutaneous Coronary Intervention', American Journal of Cardiology, 123, pp. 1941 - 1948, http://dx.doi.org/10.1016/j.amjcard.2019.03.019

Guedeney P; Claessen BE; Baber U; Camaj A; Sorrentino S; Aquino M; Blum M; Chandiramani R; Goel R; Elsayed S; Kovacic JC; Sweeny J; Barman N; Moreno P; Dangas GD; Kini A; Sharma S; Mehran R, 2019, 'Temporal Trends in Statin Prescriptions and Residual Cholesterol Risk in Patients With Stable Coronary Artery Disease Undergoing Percutaneous Coronary Intervention', American Journal of Cardiology, 123, pp. 1788 - 1795, http://dx.doi.org/10.1016/j.amjcard.2019.03.005

Guedeney P; Claessen BE; Kalkman DN; Aquino M; Sorrentino S; Giustino G; Farhan S; Vogel B; Sartori S; Montalescot G; Sweeny J; Kovacic JC; Krishnan P; Barman N; Dangas G; Kini A; Baber U; Sharma S; Mehran R, 2019, 'Residual Inflammatory Risk in Patients With Low LDL Cholesterol Levels Undergoing Percutaneous Coronary Intervention', Journal of the American College of Cardiology, 73, pp. 2401 - 2409, http://dx.doi.org/10.1016/j.jacc.2019.01.077

Price LZ; Faries PL; McKinsey JF; Prakash K; Tang GH; Kovacic JC; Tadros RO, 2019, 'The Epidemiology, Pathophysiology, and Novel Treatment of Calcific Arterial Disease', Surgical technology international, 34, pp. 351 - 358

Fernandez-Jimenez R; Jaslow R; Bansilal S; Santana M; Diaz-Munoz R; Latina J; Soto AV; Vedanthan R; Al-Kazaz M; Giannarelli C; Kovacic JC; Bagiella E; Kasarskis A; Fayad ZA; Hajjar RJ; Fuster V, 2019, 'Child Health Promotion in Underserved Communities: The FAMILIA Trial', Journal of the American College of Cardiology, 73, pp. 2011 - 2021, http://dx.doi.org/10.1016/j.jacc.2019.01.057

Zhang Z; Cheng H; Hong X; DI Narzo AF; Franzen O; Peng S; Ruusalepp A; Kovacic JC; Bjorkegren JLM; Wang X; Hao K, 2019, 'EnsembleCNV: An ensemble machine learning algorithm to identify and genotype copy number variation using SNP array data', Nucleic Acids Research, 47, http://dx.doi.org/10.1093/nar/gkz068

Gornik HL; Persu A; Adlam D; Aparicio LS; Azizi M; Boulanger M; Bruno RM; de Leeuw P; Fendrikova-Mahlay N; Froehlich J; Ganesh SK; Gray BH; Jamison C; Januszewicz A; Jeunemaitre X; Kadian-Dodov D; Kim ESH; Kovacic JC; Mace P; Morganti A; Sharma A; Southerland AM; Touzé E; van der Niepen P; Wang J; Weinberg I; Wilson S; Olin JW; Plouin PF, 2019, 'First International Consensus on the diagnosis and management of fibromuscular dysplasia', Vascular Medicine United Kingdom, 24, pp. 164 - 189, http://dx.doi.org/10.1177/1358863X18821816

Kovacic JC; Dimmeler S; Harvey RP; Finkel T; Aikawa E; Krenning G; Baker AH, 2019, 'Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review', Journal of the American College of Cardiology, 73, pp. 190 - 209, http://dx.doi.org/10.1016/j.jacc.2018.09.089

Adlam D; Olson TM; Combaret N; Kovacic JC; Iismaa SE; Al-Hussaini A; O'Byrne MM; Bouajila S; Georges A; Mishra K; Braund PS; d'Escamard V; Huang S; Margaritis M; Nelson CP; de Andrade M; Kadian-Dodov D; Welch CA; Mazurkiewicz S; Jeunemaitre X; Wong CMY; Giannoulatou E; Sweeting M; Muller D; Wood A; McGrath-Cadell L; Fatkin D; Dunwoodie SL; Harvey R; Holloway C; Empana JP; Jouven X; Olin JW; Gulati RMD; Tweet MS; Hayes SN; Samani NJ; Graham RM; Motreff P; Bouatia-Naji N; Nikpay M; Goel A; Won HH; Hall LM; Willenborg C; Kanoni S; Saleheen D; Kyriakou T; Nelson CP; Hopewell JC; Webb TR; Zeng L; Dehghan A; Alver M; Armasu SM; Auro K; Bjonnes A; Chasman DI; Chen S; Ford I; Franceschini N; Gieger C; Grace C; Gustafsson S; Huang J; Hwang SJ; Kim YK; Kleber ME; Lau KW; Lu X; Lu Y; Lyytikäinen LP; Mihailov E; Morrison A; Pervjakova N; Qu L; Rose LM; Salfati E; Saxena R; Scholz M; Smith AV; Tikkanen E; Uitterlinden A; Yang X; Zhang W; Zhao W; de Andrade M; de Vries PS; van Zuydam NR; Anand SS; Bertram L; Beutner F; Dedoussis G; Frossard P; Gauguier D; Goodall AH; Gottesman O; Haber M; Han BG; Huang J, 2019, 'Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection', Journal of the American College of Cardiology, 73, pp. 58 - 66, http://dx.doi.org/10.1016/j.jacc.2018.09.085

Gornik HL; Persu A; Adlam D; Aparicio LS; Azizi M; Boulanger M; Bruno RM; De Leeuw P; Fendrikova-Mahlay N; Froehlich J; Ganesh SK; Gray BH; Jamison C; Januszewicz A; Jeunemaitre X; Kadian-Dodov D; Kim ESH; Kovacic JC; MacE P; Morganti A; Sharma A; Southerland AM; Touzé E; Van Der Niepen P; Wang J; Weinberg I; Wilson S; Olin JW; Plouin PF, 2019, 'First international consensus on the diagnosis and management of fibromuscular dysplasia', Journal of Hypertension, 37, pp. 229 - 252, http://dx.doi.org/10.1097/HJH.0000000000002019

Frades I; Readhead B; Amadori L; Koplev S; Talukdar HA; Crane HM; Crane PK; Kovacic JC; Dudley JT; Giannarelli C; Björkegren JLM; Peter I, 2019, 'Systems pharmacology identifies an arterial wall regulatory gene network mediating coronary artery disease side effects of antiretroviral therapy', Circulation Genomic and Precision Medicine, 12, pp. 262 - 272, http://dx.doi.org/10.1161/CIRCGEN.118.002390

Guedeney P; Baber U; Claessen B; Aquino M; Camaj A; Sorrentino S; Vogel B; Farhan S; Faggioni M; Chandrasekhar J; Kalkman DN; Kovacic JC; Sweeny J; Barman N; Moreno P; Vijay P; Shah S; Dangas G; Kini A; Sharma S; Mehran R, 2019, 'Temporal trends, determinants, and impact of high-intensity statin prescriptions after percutaneous coronary intervention: Results from a large single-center prospective registry', American Heart Journal, 207, pp. 10 - 18, http://dx.doi.org/10.1016/j.ahj.2018.09.001

Kalkman DN; Aquino M; Claessen BE; Baber U; Guedeney P; Sorrentino S; Vogel B; De Winter RJ; Sweeny J; Kovacic JC; Shah S; Vijay P; Barman N; Kini A; Sharma S; Dangas GD; Mehran R, 2018, 'Residual inflammatory risk and the impact on clinical outcomes in patients after percutaneous coronary interventions', European Heart Journal, 39, pp. 4101 - 4108, http://dx.doi.org/10.1093/eurheartj/ehy633

Peng S; Deyssenroth MA; Di Narzo AF; Cheng H; Zhang Z; Lambertini L; Rusualepp A; Kovacic JC; Bjorkegren JLM; Marsit CJ; Chen J; Hao K, 2018, 'Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity', Plos Genetics, 14, http://dx.doi.org/10.1371/journal.pgen.1007799

Robson PM; Trivieri MG; Karakatsanis NA; Padilla M; Abgral R; Dweck MR; Kovacic JC; Fayad ZA, 2018, 'Correction of respiratory and cardiac motion in cardiac PET/MR using MR-based motion modeling', Physics in Medicine and Biology, 63, http://dx.doi.org/10.1088/1361-6560/aaea97

Williams JW; Giannarelli C; Rahman A; Randolph GJ; Kovacic JC, 2018, 'Macrophage Biology, Classification, and Phenotype in Cardiovascular Disease: JACC Macrophage in CVD Series (Part 1)', Journal of the American College of Cardiology, 72, pp. 2166 - 2180, http://dx.doi.org/10.1016/j.jacc.2018.08.2148

Moore KJ; Koplev S; Fisher EA; Tabas I; Björkegren JLM; Doran AC; Kovacic JC, 2018, 'Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)', Journal of the American College of Cardiology, 72, pp. 2181 - 2197, http://dx.doi.org/10.1016/j.jacc.2018.08.2147

Fayad ZA; Swirski FK; Calcagno C; Robbins CS; Mulder W; Kovacic JC, 2018, 'Monocyte and Macrophage Dynamics in the Cardiovascular System: JACC Macrophage in CVD Series (Part 3)', Journal of the American College of Cardiology, 72, pp. 2198 - 2212, http://dx.doi.org/10.1016/j.jacc.2018.08.2150

Lavine KJ; Pinto AR; Epelman S; Kopecky BJ; Clemente-Casares X; Godwin J; Rosenthal N; Kovacic JC, 2018, 'The Macrophage in Cardiac Homeostasis and Disease: JACC Macrophage in CVD Series (Part 4)', Journal of the American College of Cardiology, 72, pp. 2213 - 2230, http://dx.doi.org/10.1016/j.jacc.2018.08.2149

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