By Dr Jaesung Peter Choi

Book Chapters

Choi JP; Zheng X, 2020, 'Generation of cerebral cavernous malformation in neonatal mouse models using inducible Cre-loxP strategy', in Methods in Molecular Biology, pp. 253 - 258, http://dx.doi.org/10.1007/978-1-0716-0640-7_18

Journal articles

Suwal N; Thapa R; Bashyal S; Sugandhi VV; Subedi S; Panth N; Amorim N; Choi JP; Gupta M; Idrees S; Dua K; Paudel KR, 2025, 'Targeting oncogenic signaling pathways in lung Cancer: The emerging role of nobiletin, a flavonoid from citrus peel', Food Bioscience, 69, http://dx.doi.org/10.1016/j.fbio.2025.106887

Qian C; Zhou Y; Zhang T; Dong G; Song M; Tang Y; Wei Z; Yu S; Shen Q; Chen W; Choi JP; Yan J; Zhong C; Wan L; Li J; Wang A; Lu Y; Zhao Y, 2024, 'Targeting PKM2 signaling cascade with salvianic acid A normalizes tumor blood vessels to facilitate chemotherapeutic drug delivery', Acta Pharmaceutica Sinica B, 14, pp. 2077 - 2096, http://dx.doi.org/10.1016/j.apsb.2024.02.003

Chopra N; Menounos S; Choi JP; Hansbro PM; Diwan AD; Das A, 2022, 'Blood-Spinal Cord Barrier: Its Role in Spinal Disorders and Emerging Therapeutic Strategies', NEUROSCI, 3, pp. 1 - 27, http://dx.doi.org/10.3390/neurosci3010001

Wang R; Wu ST; Yang X; Qian Y; Choi JP; Gao R; Song S; Wang Y; Zhuang T; Wong JJL; Zhang Y; Han Z; Lu HA; Alexander SI; Liu R; Xia Y; Zheng X, 2021, 'Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting', Jci Insight, 6, http://dx.doi.org/10.1172/jci.insight.142838

Choi JP; Yang X; He S; Song R; Xu ZR; Foley M; Wong JJL; Xu CR; Zheng X, 2021, 'CCM2L (Cerebral Cavernous Malformation 2 Like) Deletion Aggravates Cerebral Cavernous Malformation Through Map3k3-KLF Signaling Pathway', Stroke, 52, pp. 1428 - 1436, http://dx.doi.org/10.1161/STROKEAHA.120.031523

Donovan C; Liu G; Shen S; Marshall JE; Kim RY; Alemao CA; Budden KF; Choi JP; Kohonen-Corish M; El-Omar EM; Yang IA; Hansbro PM, 2020, 'The role of the microbiome and the NLRP3 inflammasome in the gut and lung', Journal of Leukocyte Biology, 108, pp. 925 - 935, http://dx.doi.org/10.1002/JLB.3MR0720-472RR

Li J; Zhao Y; Choi J; Ting KK; Coleman P; Chen J; Cogger VC; Wan L; Shi Z; Moller T; Zheng X; Vadas MA; Gamble JR, 2020, 'Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice', Plos Biology, 18, http://dx.doi.org/10.1371/journal.pbio.3000734

Hong CC; Tang AT; Detter MR; Choi JP; Wang R; Yang X; Guerrero AA; Wittig CF; Hobson N; Girard R; Lightle R; Moore T; Shenkar R; Polster SP; Goddard LM; Ren AA; Leu NA; Sterling S; Yang J; Li L; Chen M; Mericko-Ishizuka P; Dow LE; Watanabe H; Schwaninger M; Min W; Marchuk DA; Zheng X; Awad IA; Kahn ML, 2020, 'Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican', Journal of Experimental Medicine, 217, http://dx.doi.org/10.1084/JEM.20200140

Li J; Zhao Y; Coleman P; Chen J; Ting KK; Choi JP; Zheng X; Vadas MA; Gamble JR, 2019, 'Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways', Biochimica Et Biophysica Acta Molecular Basis of Disease, 1865, http://dx.doi.org/10.1016/j.bbadis.2019.07.013

Choi JP; Wang R; Yang X; Wang X; Wang L; Ting KK; Foley M; Cogger V; Yang Z; Liu F; Han Z; Liu R; Baell J; Zheng X, 2018, 'Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations', Sci Adv, 4, pp. eaau0731, http://dx.doi.org/10.1126/sciadv.aau0731

Choi JP; Yang X; Foley M; Wang X; Zheng X, 2017, 'Induction and micro-CT imaging of cerebral cavernous malformations in mouse model', Journal of Visualized Experiments, 2017, http://dx.doi.org/10.3791/56476

Tang AT; Choi JP; Kotzin JJ; Yang Y; Hong CC; Hobson N; Girard R; Zeineddine HA; Lightle R; Moore T; Cao Y; Shenkar R; Chen M; Mericko P; Yang J; Li L; Tanes C; Kobuley D; Võsa U; Whitehead KJ; Li DY; Franke L; Hart B; Schwaninger M; Henao-Mejia J; Morrison L; Kim H; Awad IA; Zheng X; Kahn ML, 2017, 'Endothelial TLR4 and the microbiome drive cerebral cavernous malformations', Nature, 545, pp. 305 - 310, http://dx.doi.org/10.1038/nature22075

Choi JP; Foley M; Zhou Z; Wong WY; Gokoolparsadh N; Arthur JSC; Li DY; Zheng X, 2016, 'Micro-CT imaging reveals Mekk3 heterozygosity prevents cerebral cavernous malformations in Ccm2-deficient mice', Plos One, 11, http://dx.doi.org/10.1371/journal.pone.0160833

Choi JP; Zheng Y; Handelsman DJ; Simanainen U, 2016, 'Glandular epithelial AR inactivation enhances PTEN deletion-induced uterine pathology', Endocrine Related Cancer, 23, pp. 377 - 390, http://dx.doi.org/10.1530/ERC-16-0039

Choi JP; Zheng Y; Skulte KA; Handelsman DJ; Simanainen U, 2015, 'Development and characterization of uterine glandular epithelium specific androgen receptor knockout mouse model', Biology of Reproduction, 93, http://dx.doi.org/10.1095/biolreprod.115.132241

Choi J; Desai R; Zheng Y; Yao M; Dong Q; Watson G; Handelsman DJ; Simanainen U, 2015, 'Androgen actions via androgen receptor promote PTEN inactivation induced uterine cancer', Endocrine Related Cancer, 22, pp. 687 - 701, http://dx.doi.org/10.1530/ERC-15-0203

Choi J; Psarommatis B; Gao YR; Zheng Y; Handelsman DJ; Simanainen U, 2014, 'The role of androgens in experimental rodent mammary carcinogenesis', Breast Cancer Research, 16, http://dx.doi.org/10.1186/s13058-014-0483-x

Zhao B; Choi J; Jaehne M; Gao YR; Desai R; Tuckermann J; Zhou H; Handelsman DJ; Simanainen U, 2014, 'Glucocorticoid receptor in prostate epithelia is not required for corticosteroid-induced epithelial hyperproliferation in the mouse prostate', Prostate, 74, pp. 1068 - 1078, http://dx.doi.org/10.1002/pros.22825

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