By Dr Charles Cox

Preprints

Lin Y; Zhou Z; Han Y; Cheng D; Wang H; Ju AL; Zhang Y; Cox CD; Corry B, 2025, TMEM63 proteins act as mechanically activated cholesterol modulated lipid scramblases contributing to membrane mechano-resilience, http://dx.doi.org/10.1101/2025.07.26.664997

Yu Z-Y; Guo Y; Kesteven S; Cheng D; Lei H; Wu J; Nadar E; Macdonald P; Xaymardan M; Cox C; Feneley M; Martinac B, 2025, Deletion of PIEZO1 in adult cardiomyocytes accelerates cardiac aging and causes premature death, http://dx.doi.org/10.1101/2025.01.20.633994

Ju L; Wang H; Vatankhah P; Wang Y; Russel B; Su Q; Zhou Z; Cox C; Jin J, 2023, Microscale geometrical modulation of PIEZO1 mediated cell mechanosensing via cytoskeletal redistribution buckle, http://dx.doi.org/10.21203/rs.3.rs-3218836/v1

Zhang Y; Jiang F; Zhao YC; Cho A-N; Fang G; Cox CD; Zreiqat H; Lu ZF; Lu H; Ju LA, 2022, 3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay, http://dx.doi.org/10.1101/2022.11.19.517181

Yang S; Miao X; Arnold S; Li B; Ly A; Wang H; Wang M; Guo X; Pathak M; Zhao W; Cox C; Shi Z, 2022, Membrane curvature governs the distribution of Piezo1 in live cells, http://dx.doi.org/10.1101/2022.06.22.497259

Yu Z-Y; Gong H; Kesteven S; Guo Y; Wu J; Li J; Iismaa S; Kaidonis X; Graham R; Cox C; Feneley M; Martinac B, 2021, Piezo1 is the cardiac mechanosensor that initiates the hypertrophic response to pressure overload, http://dx.doi.org/10.21203/rs.3.rs-895561/v1

Kuchel PW; Cox CD; Daners D; Shishmarev D; Galvosas P, 2021, Surface model of the human red blood cell simulating changes in membrane curvature under strain, http://dx.doi.org/10.21203/rs.3.rs-467222/v1

Cox CD; Zhang Y; Zhou Z; Walz T; Martinac B, 2021, Cyclodextrins increase membrane tension and are universal activators of mechanosensitive channels, http://dx.doi.org/10.1101/2021.03.08.434340

Li JV; Ng C-A; Cheng D; Yao M; Guo Y; Yu Z-Y; Ramaswamy Y; Ju LA; Kuchel PW; Feneley MP; Fatkin D; Cox CD, 2020, Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations, http://dx.doi.org/10.1101/2020.11.30.404962

Kuchel P; Romanenko K; Shishmarev D; Galvosas P; Cox C, 2020, Enhanced Ca2+ Influx in Mechanically Distorted Erythrocytes: Measurements with 19F Nuclear Magnetic Resonance Spectroscopy, http://dx.doi.org/10.21203/rs.3.rs-107038/v1

Pineda S; Nikolova-Krstevski V; Leimena C; Atkinson AJ; Altekoester A-K; Cox CD; Jacoby A; Huttner IG; Ju Y-K; Soka M; Ohanian M; Trivedi G; Kalvakuri S; Johnson R; Molenaar P; Kuchar D; Allen DG; van Helden DF; Harvey RP; Hill AP; Bodmer R; Vogler G; Dobrzynski H; Ocorr K; Fatkin D, 2020, Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, K_Ca1.1, in Sinus Node Function and Arrhythmia Risk, http://dx.doi.org/10.1101/2020.06.28.176495

Yao M; Tijore A; Cheng D; Li JV; Hariharan A; Martinac B; Van Nhieu GT; Cox CD; Sheetz M, 2020, Force-dependent recruitment of Piezo1 drives adhesion maturation and calcium entry in normal but not tumor cells, http://dx.doi.org/10.1101/2020.03.09.972307

Romanov V; Silvani G; Zhu H; Cox C; Martinac B, 2020, An acoustic platform for single-cell, high-throughput measurements of the viscoelastic properties of cells, http://dx.doi.org/10.1101/2020.09.07.286898

Silvani G; Romanov V; Cox C; Martinac B, 2020, Biomechanical characterization of endothelial cells exposed to shear stress using acoustic force spectroscopy, http://dx.doi.org/10.1101/2020.09.29.319772

Guo Y; Yu Z-Y; Wu J; Gong H; Kesteven S; Iismaa S; Chan A; Holman S; Pinto S; Pironet A; Cox C; Graham R; Vennekens R; Feneley M; Martinac B, 2020, The Ca²⁺-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy, http://dx.doi.org/10.1101/2020.12.21.423727

Xue F; Cox CD; Bavi N; Rohde PR; Nakayama Y; Martinac B, 2019, Membrane stiffness is a key determinant of E coli MscS channel mechanosensitivity, http://dx.doi.org/10.1101/790501

Ridone P; Pandzic E; Vassalli M; Cox CD; Macmillan A; Gottlieb PA; Martinac B, 2019, Disruption of membrane cholesterol organization impairs the concerted activity of PIEZO1 channel clusters, http://dx.doi.org/10.1101/604488

Buyan A; Cox C; Rae J; Barnoud J; Li J; Cvetovska J; Bastiani M; Chan HSM; Hodson M; Martinac B; Parton R; Marrink S; Corry B, 2019, Piezo1 Induces Local Curvature in a Mammalian Membrane and Forms Specific Protein-Lipid Interactions, http://dx.doi.org/10.1101/787531

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