By Dr Chantal Kopecky

Journal articles

Silvani G; Kopecky C; Romanazzo S; Rodríguez V; Das A; Pandzic E; Lock JG; Chaffer CL; Poole K; Kilian KA, 2025, 'Capillary constrictions prime cancer cell tumorigenicity through PIEZO1', Nature Communications, 16, http://dx.doi.org/10.1038/s41467-025-63374-6

Johnson KK; Koshy P; Kopecky C; Devadason M; Holst J; Kilian KA; Sorrell CC, 2025, 'Theranostic performance of EGFR-targeted ceria-based nanoparticles on EGFR-positive cancers', Journal of Biomaterials Applications, 40, pp. 454 - 469, http://dx.doi.org/10.1177/08853282251336556

Leinweber ME; Walter C; Assadian A; Kopecky C; Domenig O; Kovarik JJ; Hofmann AG, 2025, 'Angiotensin Dysregulation in Patients with Arterial Aneurysms', International Journal of Molecular Sciences, 26, http://dx.doi.org/10.3390/ijms26041502

Johnson KK; Koshy P; Kopecky C; Devadason M; Biazik J; Zheng X; Jiang Y; Wang X; Liu Y; Holst J; Yang JL; Kilian KA; Sorrell CC, 2024, 'ROS-mediated anticancer effects of EGFR-targeted nanoceria', Journal of Biomedical Materials Research Part A, 112, pp. 754 - 769, http://dx.doi.org/10.1002/jbm.a.37656

Kopecky C; Haug M; Reischl B; Deshpande N; Manandhar B; King TW; Lee V; Wilkins MR; Morris M; Polly P; Friedrich O; Rye KA; Cochran BJ, 2024, 'Effect of insulin insufficiency on ultrastructure and function in skeletal muscle', Journal of Cachexia Sarcopenia and Muscle, 15, pp. 112 - 123, http://dx.doi.org/10.1002/jcsm.13380

Liu Y; Nemec S; Kopecky C; Stenzel MH; Kilian KA, 2023, 'Hydrogel Microtumor Arrays to Evaluate Nanotherapeutics', Advanced Healthcare Materials, 12, http://dx.doi.org/10.1002/adhm.202201696

Molley TG; Jiang S; Ong L; Kopecky C; Ranaweera CD; Jalandhra GK; Milton L; Kardia E; Zhou Z; Rnjak-Kovacina J; Waters SA; Toh YC; Kilian KA, 2023, 'Gas-modulating microcapsules for spatiotemporal control of hypoxia', Proceedings of the National Academy of Sciences of the United States of America, 120, pp. e2217557120, http://dx.doi.org/10.1073/pnas.2217557120

Srivastava P; Romanazzo S; Kopecky C; Nemec S; Ireland J; Molley TG; Lin K; Jayathilaka PB; Pandzic E; Yeola A; Chandrakanthan V; Pimanda J; Kilian K, 2023, 'Defined Microenvironments Trigger In Vitro Gastrulation in Human Pluripotent Stem Cells', Advanced Science, 10, http://dx.doi.org/10.1002/advs.202203614

K. Johnson K; Kopecky C; Koshy P; Liu Y; Devadason M; Holst J; A. Kilian K; C. Sorrell C, 2023, 'Theranostic Activity of Ceria-Based Nanoparticles toward Parental and Metastatic Melanoma: 2D vs 3D Models', ACS Biomaterials Science and Engineering, 9, pp. 1053 - 1065, http://dx.doi.org/10.1021/acsbiomaterials.2c01258

Romanazzo S; Kopecky C; Jiang S; Doshi R; Mukund V; Srivastava P; Rnjak-Kovacina J; Kelly K; Kilian KA, 2022, 'Biomaterials directed activation of a cryostable therapeutic secretome in induced pluripotent stem cell derived mesenchymal stromal cells', Journal of Tissue Engineering and Regenerative Medicine, 16, pp. 1008 - 1018, http://dx.doi.org/10.1002/term.3347

Nemec S; Ganda S; Al Taief K; Kopecky C; Kuchel R; Lebhar H; Marquis CP; Thordarson P; Kilian KA, 2022, 'A Tunable Tumor Microenvironment through Recombinant Bacterial Collagen-Hyaluronic Acid Hydrogels', ACS Applied Bio Materials, 5, pp. 4581 - 4588, http://dx.doi.org/10.1021/acsabm.2c00186

Antlanger M; Domenig O; Kaltenecker CC; Kovarik JJ; Rathkolb V; Müller MM; Schwaiger E; Hecking M; Poglitsch M; Säemann MD; Kopecky C, 2022, 'Combined sodium glucose co-transporter-2 inhibitor and angiotensin-converting enzyme inhibition upregulates the renin-angiotensin system in chronic kidney disease with type 2 diabetes: Results of a randomized, double-blind, placebo-controlled exploratory trial', Diabetes Obesity and Metabolism, 24, pp. 816 - 826, http://dx.doi.org/10.1111/dom.14639

Kokkinos J; Sharbeen G; Haghighi KS; Ignacio RMC; Kopecky C; Gonzales-Aloy E; Youkhana J; Timpson P; Pereira BA; Ritchie S; Pandzic E; Boyer C; Davis TP; Butler LM; Goldstein D; McCarroll JA; Phillips PA, 2021, 'Ex vivo culture of intact human patient derived pancreatic tumour tissue', Scientific Reports, 11, pp. 1944, http://dx.doi.org/10.1038/s41598-021-81299-0

Kovarik JJ; Kaltenecker CC; Domenig O; Antlanger M; Poglitsch M; Kopecky C; Säemann MD, 2021, 'Effect of Mineralocorticoid Receptor Antagonism and ACE Inhibition on Angiotensin Profiles in Diabetic Kidney Disease: An Exploratory Study', Diabetes Therapy, 12, pp. 2485 - 2498, http://dx.doi.org/10.1007/s13300-021-01118-7

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496

Kokkinos J; Ignacio RM; Haghighi K; Kopecky C; Sharbeen G; Gonzales-Aloy E; Youkhana J; Butler L; Goldstein D; McCarroll J; Phillips P, 2021, 'Patient-derived pancreatic tumours in a dish: implications for real-time precision medicine', HPB, 23, pp. S235 - S235, http://dx.doi.org/10.1016/j.hpb.2020.11.590

Kaltenecker CC; Domenig O; Kopecky C; Antlanger M; Poglitsch M; Berlakovich G; Kain R; Stegbauer J; Rahman M; Hellinger R; Gruber C; Grobe N; Fajkovic H; Eskandary F; Böhmig GA; Säemann MD; Kovarik JJ, 2020, 'Critical Role of Neprilysin in Kidney Angiotensin Metabolism', Circulation Research, 127, pp. 593 - 606, http://dx.doi.org/10.1161/CIRCRESAHA.119.316151

Kovarik JJ; Kaltenecker CC; Kopecky C; Domenig O; Antlanger M; Werzowa J; Eskandary F; Kain R; Poglitsch M; Schmaldienst S; Böhmig GA; Säemann MD, 2019, 'Intrarenal Renin-Angiotensin-System Dysregulation after Kidney Transplantation', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-46114-x

Kopecky C; Lytvyn Y; Domenig O; Antlanger M; Kovarik JJ; Kaltenecker CC; Poglitsch M; Perkins BA; Rye KA; Cherney DZI; Säemann MD, 2019, 'Molecular regulation of the renin–angiotensin system by sodium–glucose cotransporter 2 inhibition in type 1 diabetes mellitus', Diabetologia, 62, pp. 1090 - 1093, http://dx.doi.org/10.1007/s00125-019-4871-8

Kopecky C; Pandzic E; Parmar A; Szajer J; Lee V; Dupuy A; Arthur A; Fok S; Whan R; Ryder WJ; Rye KA; Cochran BJ, 2019, 'Translocator protein localises to CD11b + macrophages in atherosclerosis', Atherosclerosis, 284, pp. 153 - 159, http://dx.doi.org/10.1016/j.atherosclerosis.2019.03.011

Schwaiger E; Burghart L; Signorini L; Ristl R; Kopecky C; Tura A; Pacini G; Wrba T; Antlanger M; Schmaldienst S; Werzowa J; Säemann MD; Hecking M, 2019, 'Empagliflozin in posttransplantation diabetes mellitus: A prospective, interventional pilot study on glucose metabolism, fluid volume, and patient safety', American Journal of Transplantation, 19, pp. 907 - 919, http://dx.doi.org/10.1111/ajt.15223

Raupachova J; Kopecky C; Cohen G, 2019, 'High-density lipoprotein from chronic kidney disease patients modulates polymorphonuclear leukocytes', Toxins, 11, http://dx.doi.org/10.3390/toxins11020073

Reinthaler EM; Graf E; Zrzavy T; Wieland T; Hotzy C; Kopecky C; Pferschy S; Schmied C; Leutmezer F; Keilani M; Lill CM; Hoffjan S; Epplen JT; Zettl UK; Hecker M; Deutschländer A; Meuth SG; Ahram M; Mustafa B; El-Khateeb M; Vilariño-Güell C; Dessa Sadovnick A; Zimprich F; Tomkinson B; Strom T; Kristoferitsch W; Lassmann H; Zimprich A, 2018, 'TPP2 mutation associated with sterile brain inflammation mimicking MS', Neurology Genetics, 4, http://dx.doi.org/10.1212/NXG.0000000000000285

Werzowa JM; Säemann MD; Mohl A; Bergmann M; Kaltenecker CC; Brozek W; Thomas A; Haidinger M; Antlanger M; Kovarik JJ; Kopecky C; Song PXK; Budde K; Pascual J; Hecking M, 2018, 'A randomized controlled trial-based algorithm for insulin-pump therapy in hyperglycemic patients early after kidney transplantation', Plos One, 13, http://dx.doi.org/10.1371/journal.pone.0193569

Sponder M; Kopecky C; Campean IA; Emich M; Fritzer-Szekeres M; Litschauer B; Graf S; Säemann MD; Strametz-Juranek J, 2017, 'Sports and HDL-quality reflected by serum amyloid A and surfactant protein B', International Journal of Medical Sciences, 14, pp. 1040 - 1048, http://dx.doi.org/10.7150/ijms.20388

Antlanger M; Bernhofer S; Kovarik JJ; Kopecky C; Kaltenecker CC; Domenig O; Poglitsch M; Säemann MD, 2017, 'Effects of direct renin inhibition versus angiotensin II receptor blockade on angiotensin profiles in non-diabetic chronic kidney disease', Annals of Medicine, 49, pp. 525 - 533, http://dx.doi.org/10.1080/07853890.2017.1313447

Sponder M; Kopecky C; Campean IA; Emich M; Bergler-Klein J; Graf S; Saeemann M; Strametz-Juranek J, 2017, 'P5311Influence of physical activity on hdl-quality reflected by serum amyloid a and surfactant protein b', European Heart Journal, 38, http://dx.doi.org/10.1093/eurheartj/ehx493.p5311

Kopecky C; Michlits G; Säemann MD; Weichhart T, 2017, 'Pro- versus Anti-inflammatory Actions of HDLs in Innate Immunity', Cell Metabolism, 26, pp. 2 - 3, http://dx.doi.org/10.1016/j.cmet.2017.04.007

Antlanger M; Aschauer S; Kopecky C; Hecking M; Kovarik JJ; Werzowa J; Mascherbauer J; Genser B; Säemann MD; Bonderman D, 2017, 'Heart failure with preserved and reduced ejection fraction in hemodialysis patients: Prevalence, disease prediction and prognosis', Kidney and Blood Pressure Research, 42, pp. 165 - 176, http://dx.doi.org/10.1159/000473868

Kovarik JJ; Kopecky C; Antlanger M; Domenig O; Kaltenecker CC; Werzowa J; Hecking M; Mahr S; Grömmer M; Wallner C; Aumayr K; Kain R; Zuckermann A; Poglitsch M; Säemann MD, 2017, 'Effects of angiotensin-converting-enzyme inhibitor therapy on the regulation of the plasma and cardiac tissue renin-angiotensin system in heart transplant patients', Journal of Heart and Lung Transplantation, 36, pp. 355 - 365, http://dx.doi.org/10.1016/j.healun.2016.08.022

Kopecky C; Ebtehaj S; Genser B; Drechsler C; Krane V; Antlanger M; Kovarik JJ; Kaltenecker CC; Parvizi M; Wanner C; Weichhart T; Säemann MD; Tietge UJF, 2017, 'HDL Cholesterol efflux does not predict cardiovascular risk in hemodialysis patients', Journal of the American Society of Nephrology, 28, pp. 769 - 775, http://dx.doi.org/10.1681/ASN.2016030262

Antlanger M; Domenig O; Kovarik JJ; Kaltenecker CC; Kopecky C; Poglitsch M; Säemann MD, 2017, 'Molecular remodeling of the renin-angiotensin system after kidney transplantation', JRAAS Journal of the Renin Angiotensin Aldosterone System, 18, http://dx.doi.org/10.1177/1470320317705

Kovarik JJ; Antlanger M; Domenig O; Kaltenecker CC; Hecking M; Haidinger M; Werzowa J; Kopecky C; Säemann MD, 2016, 'Erratum: Molecular regulation of the renin-angiotensin system in haemodialysis patients. (Nephrol. Dial. Transplant. (2015) 30 (1) (115-123)) doi: 10.1093/ndt/gfu265', Nephrology Dialysis Transplantation, 31, pp. 851, http://dx.doi.org/10.1093/ndt/gfw071

Ebtehaj S; Kopecky C; Genser B; Drechsler C; Krane V; Antlanger M; J. Kovarik J; C. Kaltenecker C; Parvizi M; Wanner C; Weichhart T; Säemann MD; Tietge UJ, 2016, 'Abstract 622: High-density Lipoprotein Cholesterol Efflux Does Not Predict Cardiovascular Risk in Hemodialysis Patients', Arteriosclerosis, Thrombosis, and Vascular Biology, 36, http://dx.doi.org/10.1161/atvb.36.suppl_1.622

Kopecky C; Ebtehaj S; Genser B; Wanner C; Saemann MD; Tietge U, 2016, 'HDL cholesterol efflux is not predictive of cardiovascular risk in diabetic patients on hemodialysis', Atherosclerosis, 252, pp. e107 - e107, http://dx.doi.org/10.1016/j.atherosclerosis.2016.07.594

Kovarik JJ; Kaltenecker CC; Domenig O; Kopecky C; Antlanger M; Poglitsch M; Kain R; Eskandary F; Böhmig GA; Säemann MD, 2016, 'MO020CHYMASE AND NEPRILYSIN ARE KEY REGULATORS OF THE CLASSICAL AND ALTERNATIVE RENIN ANGIOTENSIN SYSTEM (RAS) AFTER KIDNEY TRANSPLANTATION: IMPLICATIONS FOR RAS BLOCKINGTHERAPY', Nephrology Dialysis Transplantation, 31, pp. i36 - i36, http://dx.doi.org/10.1093/ndt/gfw133.02

Antlanger M; Domenig O; Kovarik JJ; Kaltenecker CC; Kopecky C; Poglitsch M; Säemann MD, 2016, 'MP012MOLECULAR REMODELING OF THE RENIN ANGIOTENSIN SYSTEM FOLLOWING RENAL TRANSPLANTATION', Nephrology Dialysis Transplantation, 31, pp. i347 - i347, http://dx.doi.org/10.1093/ndt/gfw181.12

Kopecky C; Ebtehaj S; Genser B; Wanner C; Säemann MD; Tietge U, 2016, 'SP479HDL CHOLESTEROL EFFLUX IS NOT PREDICTIVE OF CARDIOVASCULAR RISK IN DIABETIC PATIENTS ON HEMODIALYSIS', Nephrology Dialysis Transplantation, 31, pp. i253 - i253, http://dx.doi.org/10.1093/ndt/gfw172.19

Kopecky C; Tufaro C; Antlanger M; Säemann MD; Bonderman D, 2016, 'SP485HDL PROTEIN COMPOSITION IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION AND END STAGE RENAL DISEASE', Nephrology Dialysis Transplantation, 31, pp. i255 - i255, http://dx.doi.org/10.1093/ndt/gfw172.25

Holzer M; Schilcher G; Curcic S; Trieb M; Ljubojevic S; Stojakovic T; Scharnagl H; Kopecky CM; Rosenkranz AR; Heinemann A; Marsche G, 2015, 'Dialysis modalities and HDL composition and function', Journal of the American Society of Nephrology, 26, pp. 2267 - 2276, http://dx.doi.org/10.1681/ASN.2014030309

Kopecky C; Weichhart T; Säemann MD, 2015, 'HDL cholesterol efflux capacity and cardiovascular events [2]', New England Journal of Medicine, 372, pp. 1869, http://dx.doi.org/10.1056/NEJMc1503139

Haidinger M; Antlanger M; Kopecky C; Kovarik JJ; Säemann MD; Werzowa J, 2015, 'Post-transplantation diabetes mellitus: Evaluation of treatment strategies', Clinical Transplantation, 29, pp. 415 - 424, http://dx.doi.org/10.1111/ctr.12541

Kopecky C; Haidinger M; Birner-Grünberger R; Darnhofer B; Kaltenecker CC; Marsche G; Holzer M; Weichhart T; Antlanger M; Kovarik JJ; Werzowa J; Hecking M; Säemann MD, 2015, 'Restoration of renal function does not correct impairment of uremic HDL properties', Journal of the American Society of Nephrology, 26, pp. 565 - 575, http://dx.doi.org/10.1681/ASN.2013111219

Kopecky C; Genser B; März W; Wanner C; Säemann MD; Weichhart T, 2015, 'HDL proteins as predictors of cardiovascular risk and mortality in diabetic patients on hemodialysis', Nieren Und Hochdruckkrankheiten, 44, pp. 159 - 165, http://dx.doi.org/10.5414/NHX01694

Kopecky C; Genser B; Drechsler C; Krane V; Kaltenecker CC; Hengstschl€Ager M; M€Arz W; Wanner C; S€Aemann MD; Weichhart T, 2015, 'Quantification of HDL proteins, cardiac events, and mortality in patients with type 2 diabetes on hemodialysis', Clinical Journal of the American Society of Nephrology, 10, pp. 224 - 231, http://dx.doi.org/10.2215/CJN.06560714

Zewinger S; Drechsler C; Kleber ME; Dressel A; Riffel J; Triem S; Lehmann M; Kopecky C; Saemann MD; Lepper PM; Silbernagel G; Scharnagl H; Ritsch A; Thorand B; De Las Heras Gala T; Wagenpfeil S; Koenig W; Peters A; Laufs U; Wanner C; Fliser D; Speer T; Marz W, 2015, 'Serum amyloid A: High-density lipoproteins interaction and cardiovascular risk', European Heart Journal, 36, pp. 3007 - 3016, http://dx.doi.org/10.1093/eurheartj/ehv352

Kovarik JJ; Kaltenecker CC; Domenig O; Kopecky C; Antlanger M; Poglitsch M; Kain R; Eskandary F; Böhmig GA; Säemann MD, 2015, '8D.03', Journal of Hypertension, 33, pp. e113 - e114, http://dx.doi.org/10.1097/01.hjh.0000467657.23414.54

Zewinger S; Speer T; Drechsler C; Kleber ME; Dressel A; Riffel J; Lehmann M; Kopecky C; Säemann MD; Lepper PM; Silbernagel G; Scharnagl H; Ritsch A; Laufs U; Wanner C; Fliser D; März W, 2015, 'FO005SERUM AMYLOID A (SAA) AND HIGH DENSITY LIPOPROTEINS (HDL) INTERACTION AND CARDIOVASCULAR RISK IN RENAL PATIENTS', Nephrology Dialysis Transplantation, 30, pp. iii2 - iii2, http://dx.doi.org/10.1093/ndt/gfv135.05

Kovarik JJ; Kopecky C; Antlanger M; Domenig O; Kaltenecker CC; Werzowa J; Hecking M; Mahr S; Zuckermann A; Kain R; Poglitsch M; Säemann MD, 2015, 'FP274ACE-INDEPENDENT RAS ENZYME ACTIVITIES IN HEART TRANSPLANT PATIENTS WITH CHRONIC KIDNEY DISEASE (CKD)', Nephrology Dialysis Transplantation, 30, pp. iii158 - iii159, http://dx.doi.org/10.1093/ndt/gfv174.09

Antlanger M; Aschauer S; Kopecky C; Mascherbauer J; Bonderman D; Säemann M, 2015, 'FP608HEART FAILURE WITH PRESERVED AND REDUCED EJECTION FRACTION IN HEMODIALYSIS PATIENTS: DIAGNOSIS, PREVALENCE AND ASSOCIATED FACTORS', Nephrology Dialysis Transplantation, 30, pp. iii276 - iii276, http://dx.doi.org/10.1093/ndt/gfv181.01

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