By Associate Professor Mandy Ballinger

Journal articles

Thomas DM; Ballinger ML, 2012, 'Inherited and de novo germline TP53 mutations in adult-onset sarcoma', Hereditary cancer in clinical practice, 10, pp. A26 - A26, http://dx.doi.org/10.1186/1897-4287-10-s2-a26

Mahendran K; Ballinger M; Kirk J; Thomas D; Tattersall M, 2012, 'Pathogenic germline TP53 mutations in adult sarcoma patients; implications for treatment and screening – description of an upcoming project', Hereditary cancer in clinical practice, 10, pp. A61 - A61, http://dx.doi.org/10.1186/1897-4287-10-s2-a61

Burch ML; Ballinger ML; Yang SNY; Getachew R; Itman C; Loveland K; Osman N; Little PJ, 2010, 'Thrombin stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by protease-activated receptor-1 transactivation of the transforming growth factor βtype I receptor', Journal of Biological Chemistry, 285, pp. 26798 - 26805, http://dx.doi.org/10.1074/jbc.M109.092767

Ballinger ML; Osman N; Hashimura K; Haan JBD; Jandeleit-Dahm K; Allen T; Tannock LR; Rutledge JC; Little PJ, 2010, 'Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo', Journal of Cellular and Molecular Medicine, 14, pp. 1408 - 1418, http://dx.doi.org/10.1111/j.1582-4934.2009.00902.x

Burch ML; Yang SNY; Ballinger ML; Getachew R; Osman N; Little PJ, 2010, 'TGF-β stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2', Cellular and Molecular Life Sciences, 67, pp. 2077 - 2090, http://dx.doi.org/10.1007/s00018-010-0315-9

Cardoso LEM; Little PJ; Ballinger ML; Chan CK; Braun KR; Potter-Perigo S; Bornfeldt KE; Kinsella MG; Wight TN, 2010, 'Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways', Journal of Biological Chemistry, 285, pp. 6987 - 6995, http://dx.doi.org/10.1074/jbc.M109.088674

Getachew R; Ballinger ML; Burch ML; Little PJ; Osman N, 2010, 'Characterisation of Ki11502 as a potent inhibitor of PDGF β receptor-mediated proteoglycan synthesis in vascular smooth muscle cells', European Journal of Pharmacology, 626, pp. 186 - 192, http://dx.doi.org/10.1016/j.ejphar.2009.09.066

Getachew R; Ballinger M; Burch M; Reid J; Khachigian LM, 2010, 'PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminologycan elongationon biglycan and increases binding to LDL.', Endocrinology, 151, pp. 4356 - 4367

Ballinger ML; Ivey ME; Osman N; Thomas WG; Little PJ, 2009, 'Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL', Atherosclerosis, 205, pp. 451 - 457, http://dx.doi.org/10.1016/j.atherosclerosis.2009.01.024

Yang SNY; Burch ML; Getachew R; Ballinger ML; Osman N; Little PJ, 2009, 'Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation', Archives of Physiology and Biochemistry, 115, pp. 147 - 154, http://dx.doi.org/10.1080/13813450903110754

Osman N; Ballinger ML; Dadlani HM; Getachew R; Burch ML; Little PJ, 2008, 'p38 MAP kinase mediated proteoglycan synthesis as a target for the prevention of atherosclerosis', Cardiovascular and Hematological Disorders Drug Targets, 8, pp. 287 - 292, http://dx.doi.org/10.2174/187152908786786205

Ballinger ML; Osman N; Wilks AF; Su S; Burns CJ; Bu X; Little PJ, 2008, 'Pyrido-pyrimidine derivative CYC10424 inhibits glycosaminoglycan changes on vascular smooth muscle-derived proteoglycans and reduces lipoprotein binding', Journal of Cardiovascular Pharmacology, 52, pp. 403 - 412, http://dx.doi.org/10.1097/FJC.0b013e31818a8907

Dadlani H; Osman N; Ballinger ML; Marasco S; Little PJ, 2008, 'Calcific aortic valve disease and hypertension', Current Hypertension Reviews, 4, pp. 107 - 113, http://dx.doi.org/10.2174/157340208784245884

Dadlani H; Ballinger ML; Osman N; Getachew R; Little PJ, 2008, 'Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle', Journal of Biological Chemistry, 283, pp. 7844 - 7852, http://dx.doi.org/10.1074/jbc.M703125200

Little PJ; Ballinger ML; Survase S; Osman N; Ogru E; Geytenbeek S; Bruemmer D; Nigro J, 2008, 'Phosphorylated troglitazone activates PPARγ and inhibits vascular smooth muscle cell proliferation and proteoglycan synthesis', Journal of Cardiovascular Pharmacology, 51, pp. 274 - 279, http://dx.doi.org/10.1097/FJC.0b013e3181626ce7

Little PJ; Ballinger ML; Burch ML; Osman N, 2008, 'Biosynthesis of natural and hyperelongated chondroitin sulfate glycosaminoglycans: new insights into an elusive process.', Open Biochem J, 2, pp. 135 - 142, http://dx.doi.org/10.2174/1874091X00802010135

Little PJ; Osman N; de Dios ST; Cemerlang N; Ballinger M; Nigro J, 2007, 'Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: Thiazolidinediones (glitazones) have enhanced activity under high glucose conditions', Cardiovascular Diabetology, 6, http://dx.doi.org/10.1186/1475-2840-6-33

Grande-Allen KJ; Osman N; Ballinger ML; Dadlani H; Marasco S; Little PJ, 2007, 'Glycosaminoglycan synthesis and structure as targets for the prevention of calcific aortic valve disease', Cardiovascular Research, 76, pp. 19 - 28, http://dx.doi.org/10.1016/j.cardiores.2007.05.014

Little PJ; Ballinger ML; Osman N, 2007, 'Vascular wall proteoglycan synthesis and structure as a target for the prevention of atherosclerosis', Vascular Health and Risk Management, 3, pp. 117 - 124

de Dios ST; Frontanilla KV; Nigro J; Ballinger ML; Ivey ME; Cawson EA; Little PJ, 2007, 'Regulation of the atherogenic properties of vascular smooth muscle proteoglycans by oral anti-hyperglycemic agents', Journal of Diabetes and Its Complications, 21, pp. 108 - 117, http://dx.doi.org/10.1016/j.jdiacomp.2006.03.003

Nigro J; Ballinger M; Osman N; Dart A; Little P, 2005, 'Anti-Atherogenic Role of Peroxisome Proliferator-Activated Receptor Ligands', Current Cardiology Reviews, 1, pp. 89 - 102, http://dx.doi.org/10.2174/1573403054021654

Ballinger ML; Thomas MC; Nigro J; Ivey ME; Dilley RJ; Little PJ, 2005, 'Glycated and carboxy-methylated proteins do not directly activate human vascular smooth muscle cells', Kidney International, 68, pp. 2756 - 2765, http://dx.doi.org/10.1111/j.1523-1755.2005.00746.x

Nigro J; Ballinger ML; Survase S; Osman N; Little PJ, 2005, 'New approaches to regulating the chondroitin/dermatan sulfate glycosaminoglycan component of the vascular extracellular matrix.', Thescientificworldjournal, 5, pp. 515 - 520, http://dx.doi.org/10.1100/tsw.2005.69

Nigro J; Ballinger ML; Dilley RJ; Jennings GLR; Wight TN; Little PJ, 2004, 'Fenofibrate modifies human vascular smooth muscle proteoglycans and reduces lipoprotein binding', Diabetologia, 47, pp. 2105 - 2113, http://dx.doi.org/10.1007/s00125-004-1588-z

Ballinger ML; Nigro J; Frontanilla KV; Dart AM; Little PJ, 2004, 'Regulation of glycosaminoglycan structure and atherogenesis', Cellular and Molecular Life Sciences, 61, pp. 1296 - 1306, http://dx.doi.org/10.1007/s00018-004-3389-4

Conference Papers

Hersch J; Butow P; Latin A; O’Hara L; Ballinger ML; Laidsaar-Powell R; Bartley N; Cockburn C; Mccaffery K; Juraskova I, 2024, '103 Coproducing a novel online intervention to support shared decision making about cancer genomic testing', in ISDM Conference – AMH Randomised Trial Abstract, BMJ Publishing Group Ltd, pp. A46.2 - A46, presented at 12th International Shared Decision Making Conference, http://dx.doi.org/10.1136/bmjebm-2024-sdc.102

Zaheed M; Napier CE; Cops EJ; Ferris N; Moodie K; Milner B; Moses D; Poplawski N; Dow EG; Harris M; Tucker K; Trainer A; James P; Thomas DM; Ballinger ML, 2023, 'Long-term clinical and psychosocial outcomes of surveillance in Li Fraumeni syndrome.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2023 - 06 June 2023

Bartley N; Best MC; Biesecker BB; Fisher A; Goldstein D; Meiser B; Thomas DM; Ballinger ML; Butow P, 2021, 'Effectively communicating comprehensive tumour genomic profiling results: Mitigating uncertainty for advanced cancer patients', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 180 - 180, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000717281500295&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Vatter S; Schlub TE; Napier CE; Best MC; Bartley N; Juraskova I; Meiser B; Ballinger ML; Biesecker BB; Goldstein D; Thomas DM; Butow P, 2021, 'Psychological outcomes in advanced cancer patients after receiving genomic tumour profiling results', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 198 - 198, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000717281500332&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ballinger M, 2021, 'Surveillance in multi-organ cancer predisposition', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 73 - 73, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000717281500053&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bartley N; Napier C; Butt Z; Schlub T; Best M; Biesecker B; Ballinger M; Butow P, 2021, 'Cancer patient experience of uncertainty while waiting for genome sequencing results', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 23 - 24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000693805000035&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Best M; Butow P; Davies G; Napier C; Bartley N; Ballinger M; Biesecker BB; Juraskova I; Meiser B; Schlub T; Thomas D; Goldstein D, 2020, 'How much do cancer patients value whole genome sequencing? A cross-sectional survey using the willingness-to-pay technique', in EUROPEAN JOURNAL OF HUMAN GENETICS, SPRINGERNATURE, pp. 790 - 790, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000598482602498&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Butow P; Best M; Davies G; Schlub T; Napier C; Bartley N; Ballinger M; Juraskova I; Meiser B; Goldstein D; Biesecker B; Thomas D, 2020, 'Psychological impact of comprehensive genomic profiling results to advanced cancer patients', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 92 - 92

Best M; Butow P; Jacobs C; Savard J; Biesecker B; Ballinger M; Bartley N; Davies G; Napier CE; Smit AE; Thomas D; Newson AJ, 2019, 'Who should access germline genome sequencing? A mixed methods study of patient views', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 92 - 93, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000493438400100&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Shin SJ; Dodd E; Peng G; Bojadzieva J; Chen J; Ning J; Mai PL; Savage SA; Ballinger ML; Thomas DM; Yuan Y; Strong LC; Wang W, 2019, 'Abstract 2434: Characterizing age-of-onset of multiple primary cancers and specific cancer types in families with Li-Fraumeni syndrome', in Prevention, Early Detection, and Interception, American Association for Cancer Research, pp. 2434 - 2434, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-2434

Best M; Butow P; Bartley N; Jacobs C; Juraskova I; Newson A; Goldstein D; Savard J; Meiser B; Ballinger M; Biesecker B; Thomas D, 2019, 'Advanced cancer patient perspectives on consenting to molecular tumour profiling', in EUROPEAN JOURNAL OF HUMAN GENETICS, NATURE PUBLISHING GROUP, SWEDEN, Gothenburg, pp. 1172 - 1173, presented at 52nd Conference of the European-Society-of-Human-Genetics (ESHG), SWEDEN, Gothenburg, 15 June 2019 - 18 June 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000489313900239&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Shin SJ; Dodd E; Peng G; Bojadzieva J; Chen J; Ning J; Mai PL; Savage SA; Ballinger ML; Thomas DM; Yuan Y; Strong LC; Wang W, 2019, 'Characterizing age-of-onset of multiple primary cancers and specific cancer types in families with Li-Fraumeni syndrome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), GA, Atlanta, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-2434

Ballinger ML; Pinese M; Thomas DM, 2019, 'Translating genomic risk into an early detection strategy for sarcoma', in Genes Chromosomes and Cancer, pp. 130 - 136, http://dx.doi.org/10.1002/gcc.22697

Best M; Bartley N; Jacobs C; Juraskova I; Newson A; Savard J; Meiser B; Ballinger M; Thomas D; Biesecker B; Butow P, 2018, 'Advanced cancer patient perspectives on consenting to molecular tumour profiling: A qualitative study', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 144 - 144, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449544200232&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Best M; Bartley N; Jacobs C; Juraskova I; Newson A; Savard J; Meiser B; Ballinger M; Thomas D; Biesecker B; Butow P, 2018, 'Young cancer patient perspectives on undertaking whole genome sequencing: A qualitative study', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 144 - 144, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449544200231&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Butow P; Bartley N; Jacobs C; Juraskova I; Newson A; Savard J; Meiser B; Ballinger M; Thomas D; Biesecker B, 2018, 'Young cancerpatient perspectives on undertaking whole genome sequencing: A qualitativestudy', in EUROPEAN JOURNAL OF HUMAN GENETICS, NATURE PUBLISHING GROUP, ITALY, Milan, pp. 722 - 723, presented at 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), ITALY, Milan, 16 June 2018 - 19 June 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000489313105208&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Koster R; Panagiotou OA; Wheeler WA; Karlins E; Gastier-Foster JM; Caminada de Toledo SR; Petrilli AS; Flanagan AM; Tirabosco R; Andrulis IL; Wunder JS; Gokgoz N; Patino-Garcia A; Lecanda F; Serra M; Hattinger C; Picci P; Scotlandi K; Thomas DM; Ballinger ML; Gorlick R; Barkauskas DA; Spector LG; Tucker M; Hicks B; Yeager M; Hoover R; Chanock SJ; Savage SA; Mirabello LJ, 2018, 'Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-2077

Pinese M; Ballinger M; Thomas D, 2018, 'Abstract IA03: Translating genomic risk into an early detection strategy for sarcoma', in Clinical Cancer Research, American Association for Cancer Research (AACR), pp. IA03 - IA03, http://dx.doi.org/10.1158/1557-3265.sarcomas17-ia03

Conference Posters

McBride KA; Schlub TE; Ballinger ML; Thomas DM; Tattersall MHN, 2016, 'International survey of awareness of genetic risk in the clinical sarcoma community', Vol. 12, pp. 133 - 142, http://dx.doi.org/10.1111/ajco.12457

McBride KA; Young M-A; Schlub TE; Ballinger ML; Kirk J; Tattersall MH; Thomas DM; Mitchell G, 2014, 'THE PSYCHOLOGICAL IMPACT OF A PILOT WHOLE-BODY SCREENING TRIAL (SMOC) ON INDIVIDUALS WITH LI-FRAUMENI SYNDROME', Vol. 10, pp. 166 - 167, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345350900277&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts

Pitiyarachchi O; Lin FP; Spooner A; Sharbeen G; Barker HP; Thornton K; Collignon E; Ballinger ML; Thomas DM; Magenau A; Porazinski S; Raina A; Sjoquist KM; Chantrill LA; Gebski V; Sowmya A; Timpson P; Pajic M; Goldstein D; Phillips PA, 2024, 'Impact of symptom and functional burden on survival in pancreatic ductal adenocarcinoma (PDAC)', in ANNALS OF ONCOLOGY, ELSEVIER, SPAIN, Barcelona, Vol. 35, pp. S925 - S925, presented at Annual Congress of the European-Society-for-Medical-Oncology (ESMO), SPAIN, Barcelona, 13 September 2024 - 17 September 2024, http://dx.doi.org/10.1016/j.annonc.2024.08.1576

Kong BY; Lin FP-Y; Espinoza D; Thavaneswaran S; Meniawy T; Desai J; Harrup R; Selva-Nayagam S; Charakidis M; Cuff K; Sebastian L; Lee CK; Chinchen S; Thomas DM; Ballinger ML; Simes J; Goldstein D, 2024, 'Tucatinib and trastuzumab in advanced cancers with HER2 mutations or amplification: A molecular screening and therapeutics (MoST) program substudy', in ANNALS OF ONCOLOGY, ELSEVIER, SPAIN, Barcelona, Vol. 35, pp. S505 - S505, presented at Annual Congress of the European-Society-for-Medical-Oncology (ESMO), SPAIN, Barcelona, 13 September 2024 - 17 September 2024, http://dx.doi.org/10.1016/j.annonc.2024.08.703

Zaheed M; Grady JP; Murrow B; Douglas B; Carpenter E; Mckay S; Liang S; Taylor N; Lin FP-Y; Goldstein D; Tucker K; Thomas DM; Ballinger ML, 2024, 'Translating potential germline findings from tumour profiling into routine clinical care.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, JAPAN, Yokohama, Vol. 42, pp. 105 - 105, presented at ASCO Breakthrough: A Global Summit for Oncology Innovators, JAPAN, Yokohama, 08 August 2024 - 10 August 2024, http://dx.doi.org/10.1200/JCO.2024.42.23_suppl.105

Nagabushan S; Fuentes-Bolanos N; Lau LMS; Rumford M; Warby M; Courtney E; Grant A; Rodriguez M; Solinas A; Ziegler DS; Kellie SJ; Heath J; Ballinger M; Tucker K, 2024, 'LOW GRADE GLIOMA CAUGHT IN TRANSFORMATION: UTILITY OF COMPREHENSIVE GENOMIC PROFILING IN PEDIATRIC LI FRAUMENI SYNDROME ASSOCIATED HIGH-GRADE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, PA, Philadelphia, Vol. 26, presented at International Symposium on Pediatric Neuro-Oncology (ISPNO), PA, Philadelphia, 29 June 2024 - 02 July 2024, http://dx.doi.org/10.1093/neuonc/noae064.334

Lin FP-Y; Grady JP; Napier CE; Callow M; Thavaneswaran S; Huang ML; Zaheed M; Kansara M; Sebastian L; Ballinger ML; Simes J; Thomas DM, 2024, 'Impact of artificial intelligence (AI) decision support on clinical trial participation: A before-after implementation study on a nationwide molecular tumor board.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 42, pp. 1557 - 1557, http://dx.doi.org/10.1200/jco.2024.42.16_suppl.1557

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