Select Publications
Journal articles
, 2015, 'Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations', Science, 349, pp. 606 - 613, http://dx.doi.org/10.1126/science.aaa4282
, 2015, 'STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function', Journal of Experimental Medicine, 212, pp. 855 - 864, http://dx.doi.org/10.1084/jem.20141992
, 2015, 'T Follicular Helper Cells Have Distinct Modes of Migration and Molecular Signatures in Naive and Memory Immune Responses', Immunity, 42, pp. 704 - 718, http://dx.doi.org/10.1016/j.immuni.2015.03.002
, 2014, 'Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4', Science, 345, pp. 1623 - 1627, http://dx.doi.org/10.1126/science.1255904
, 2014, 'STAT3 is a central regulator of lymphocyte differentiation and function', Current Opinion in Immunology, 28, pp. 49 - 57, http://dx.doi.org/10.1016/j.coi.2014.01.015
, 2014, 'Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency', Nature Immunology, 15, pp. 88 - 97, http://dx.doi.org/10.1038/ni.2771
, 2014, 'Human T follicular helper (Tfh) cells and disease', Immunology and Cell Biology, 92, pp. 64 - 71, http://dx.doi.org/10.1038/icb.2013.55
, 2013, 'IL-21 signalling via STAT3 primes human näive B cells to respond to IL-2 to enhance their differentiation into plasmablasts', Blood, 122, pp. 3940 - 3950, http://dx.doi.org/10.1182/blood-2013-06-506865
, 2013, 'Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells', Journal of Experimental Medicine, 210, pp. 2739 - 2753, http://dx.doi.org/10.1084/jem.20130323
, 2013, 'Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function', Journal of Allergy and Clinical Immunology, 132, pp. 400 - 411.e9, http://dx.doi.org/10.1016/j.jaci.2013.05.029
, 2013, 'The good, the bad and the ugly-T FH cells in human health and disease', Nature Reviews Immunology, 13, pp. 412 - 426, http://dx.doi.org/10.1038/nri3447
, 2012, 'Functional STAT3 deficiency compromises the generation of human T follicular helper cells', Blood, 119, pp. 3997 - 4008, http://dx.doi.org/10.1182/blood-2011-11-392985
, 2012, 'T cell-B cell interactions in primary immunodeficiencies', Annals of the New York Academy of Sciences, 1250, pp. 1 - 13, http://dx.doi.org/10.1111/j.1749-6632.2011.06361.x
, 2011, 'Regulation of T follicular helper cell formation and function by antigen presenting cells', Current Opinion in Immunology, 23, pp. 111 - 118, http://dx.doi.org/10.1016/j.coi.2010.10.007
, 2011, 'The regulation and role of T follicular helper cells in immunity', Immunology, 134, pp. 361 - 367, http://dx.doi.org/10.1111/j.1365-2567.2011.03487.x
, 2011, 'The role of SAP and SLAM family molecules in the humoral immune response', Annals of the New York Academy of Sciences, 1217, pp. 32 - 44, http://dx.doi.org/10.1111/j.1749-6632.2010.05824.x
, 2010, 'Erratum: Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production (Nature Immunology (2009) 10 (1283-1291))', Nature Immunology, 11, pp. 644, http://dx.doi.org/10.1038/ni0710-644a
, 2010, 'c-Rel but not NF-κB1 is important for T regulatory cell development', European Journal of Immunology, 40, pp. 677 - 681, http://dx.doi.org/10.1002/eji.201040298
, 2010, 'c-Rel phenocopies PKCθ but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance', European Journal of Immunology, 40, pp. 867 - 877, http://dx.doi.org/10.1002/eji.200939445
, 2010, 'Sap is necessary for mediating antigen-specific effector functions of CD4+ AND CD8+ T cells', Pathology, 42, pp. S45 - S45, http://dx.doi.org/10.1097/01268031-201042001-00085
, 2009, 'Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production', Nature Immunology, 10, pp. 1283 - 1291, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19898472
, 2008, 'Autoimmunity: IL-21: A new player in Th17-cell differentiation (Immunology and Cell Biology (2007) 85, (503-505) DOI: 10.1038/sj.icb.7100114)', Immunology and Cell Biology, 86, pp. 478, http://dx.doi.org/10.1038/sj.icb.7100152
, 2007, 'The sound of silence: modulating anergy in T lymphocytes', Current Opinion in Immunology, 19, pp. 658 - 664, http://dx.doi.org/10.1016/j.coi.2007.08.005
, 2007, 'CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Cθ c-Rel, and protein kinase B', Journal of Immunology, 178, pp. 2932 - 2939, http://dx.doi.org/10.4049/jimmunol.178.5.2932
, 2006, 'Generation and characterization of B7-H4/B7S1/B7x-deficient mice', Molecular and Cellular Biology, 26, pp. 6403 - 6411, http://dx.doi.org/10.1128/MCB.00755-06
, 2005, 'Decision criteria for resolving isotype switching conflicts by B cells', European Journal of Immunology, 35, pp. 2949 - 2955, http://dx.doi.org/10.1002/eji.200425719
, 2004, 'TCR affinity and negative regulation limit autoimmunity', Nature Medicine, 10, pp. 1234 - 1239, http://dx.doi.org/10.1038/nm1114
, 2004, 'PKCθ Signals Activation versus Tolerance In Vivo', Journal of Experimental Medicine, 199, pp. 743 - 752, http://dx.doi.org/10.1084/jem.20031022
, 2003, 'Stochastic model of T cell proliferation: A calculus revealing IL-2 regulation of precursor frequencies, cell cycle time, and survival', Journal of Immunology, 170, pp. 4963 - 4972, http://dx.doi.org/10.4049/jimmunol.170.10.4963
, 2003, 'Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses', Journal of Immunology, 170, pp. 686 - 694, http://dx.doi.org/10.4049/jimmunol.170.2.686
, 1999, 'Quantitative analysis of lymphocyte differentiation and proliferation in vitro using carboxyfluorescein diacetate succinimidyl ester', Immunology and Cell Biology, 77, pp. 516 - 522, http://dx.doi.org/10.1046/j.1440-1711.1999.00874.x
, 1999, 'Switching to IgG3, IgG2b, and IgA is division linked and independent, revealing a stochastic framework for describing differentiation', Journal of Immunology, 163, pp. 4707 - 4714, http://dx.doi.org/10.4049/jimmunol.163.9.4707
Conference Papers
, 2021, 'Dissecting the cellular defects that lead to activated PI3K delta Syndrome (APDS)', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, pp. 110 - 110, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000753366400330&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2021, 'T cell dysfunction in Activated P13K delta Syndrome explained by cell intrinsic and extrinsic components', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000713665800408&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2014, 'Determining the Molecular Requirements for Generating Human T Follicular Helper (Tfh) Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S458 - S459, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100688&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2014, 'Dual Impairment of IL-17 and IFN-G Immunity Cause Infections by Candida and Mycobacterium in Humans with RORC Deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S485 - S486, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies (ESID), CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100745&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2014, 'Human CTLA4 Haploinsufficiency Causes Severe Immune Dysregulation', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S144 - S145, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2014, 'The Role of STAT3 in the Differentiation and Function of Unconventional T Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S441 - S441, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100651&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2012, 'PRIMARY IMMUNE DEFICIENCIES REVEAL THE ROLE OF STAT1 AND STAT3 IN THE ACTIVATION AND DIFFERENTIATION OF HUMAN CD8(+) T CELLS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 311 - 312, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900636&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2012, 'SP110 REGULATES NUCLEAR ORPHAN RECEPTOR NUR77-DRIVEN APOPTOSIS IN T CELLS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 20 - 21, presented at 15th Biennial Meeting of the European-Society-for-Primary-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900036&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2005, 'Signalling for activation versus anergy: The role of PKCI induced NF-KB activation', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 396 - 396, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700151&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2000, 'MSH2-deficiency reduces the rate of switching to all mouse isotypes without altering the regulation of switching by cell division number', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A1046 - A1046, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000086643100792&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Abstracts
, 2024, 'Mucosal-associated invariant T (MAIT) cells exhibit restricted T cell receptor β constant region usage, obfuscating assessment of T cell clonality', in Pathology, Elsevier, Vol. 56, pp. s114, http://dx.doi.org/10.1016/j.pathol.2023.12.376
, 2022, 'PATIENT PERCEPTIONS OF HEALTH-RELATED QUALITY OF LIFE IN AN AUSTRALIAN ADULT PRIMARY IMMUNODEFICIENCY COHORT', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 52, pp. 27 - 27, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000862654200072&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2020, 'A divergent transcriptional landscape underpins the development and functional branching of MAIT cells', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, HI, Honolulu, Vol. 204, presented at Annual Meeting of the American-Association-of-Immunologists - Immunology 2020, HI, Honolulu, 08 May 2020 - 12 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000589972402321&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2019, 'EVEROLIMUS-INDUCED REMISSION OF KAPOSI'S SARCOMA SECONDARY TO CRYPTIC CTLA4 SPLICING AND HAPLOINSUFFICIENCY', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 49, pp. 35 - 36, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488891400106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2016, 'Mutations underlying autosomal dominant hyper-IgE syndrome impair distinct stages of STAT3 signaling', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 139 - 140, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400280&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2016, 'Mycobacterial disease and myeloid dendritic cells defects in patients with SPPL2a deficiency', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 777 - 778, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610401757&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2016, 'STAT3 is a critical B-cell intrinsic regulator of functional antibody responses and IgE production', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 849 - 849, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2016, 'The role of STAT3 in B cells.', in Pathology, England, Vol. 48 Suppl 1, pp. S45, England, http://dx.doi.org/10.1016/j.pathol.2015.12.111