By Associate Professor David Anthony Jacques

Preprints

Mitic I; Michie K; Jacques D, 2024, Assessing the Validity of Leucine Zipper Constructs Predicted in AlphaFold2., http://dx.doi.org/10.1101/2024.10.14.618350

Yu R; Phalora P; Li N; Böcking T; Jacques DA, 2024, The Human T-cell Leukemia Virus capsid protein is a potential drug target, http://dx.doi.org/10.1101/2024.09.09.612167

Dickson CF; Hertel S; Ruan J; Ariotti N; Tuckwell A; Li N; Al-Izzi SC; Sierecki E; Gambin Y; Morris RG; Towers GJ; Böcking T; Jacques DA, 2023, Karyopherin mimicry explains how the HIV capsid penetrates nuclear pores, http://dx.doi.org/10.1101/2023.03.23.534032

Faysal KMR; Walsh JC; Renner N; Marquez CL; Shah V; Tuckwell AJ; Christie MP; Parker MW; Turville SG; James L; Towers GJ; Jacques DA; Boecking T, 2022, Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure, http://dx.doi.org/10.1101/2022.09.21.508807

Zuliani Alvarez L; Govasli ML; Rasaiyaah J; Monit C; Perry SO; Sumner RP; McAlpine-Scott S; Dickson C; Faysal KMR; Hilditch L; Miles RJ; Bibollet-Ruche F; Hahn BH; Boecking T; Pinotsis N; James LC; Jacques DA; Towers GJ, 2022, Macrophage activation of cGAS and TRIM5 distinguish pandemic and non-pandemic HIV, http://dx.doi.org/10.1101/2022.01.21.477263

Lau D; Walsh J; Dickson C; Tuckwell A; Stear J; Hunter D; Bhumkar A; Shah V; Turville S; Sierecki E; Gambin Y; Böcking T; Jacques D, 2020, Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy, http://dx.doi.org/10.1101/2020.11.13.382242

Moustaqil M; Ollivier E; Chiu H-P; Van Tol S; Rudolffi-Soto P; Stevens C; Bhumkar A; Hunter DJB; Freiberg A; Jacques D; Lee B; Sierecki E; Gambin Y, 2020, SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts, http://dx.doi.org/10.1101/2020.06.05.135699

Zeng J; Santos AF; Mukadam A; Osswald M; Luptak J; Jacques D; Dickson C; Renner N; Johnson C; Vaysburd M; McEwan W; Morais-de-Sá E; Clift D; James L, 2020, Substrate-induced clustering activates Trim-Away of pathogens and proteins, http://dx.doi.org/10.1101/2020.07.28.225359

Lau D; Walsh J; Peng W; Shah V; Turville S; Jacques D; Böcking T, 2019, Fluorescence biosensor for real-time interaction dynamics of host proteins with HIV-1 capsid tubes, http://dx.doi.org/10.1101/619841

Gupta M; Waltmann C; Renner N; Wang Y; James LC; Jacques DA; Böcking T; Voth GA, Mechanistic Insights into Lenacapavir-Induced Off-Pathway HIV-1 Capsid Assembly, http://dx.doi.org/10.1101/2025.08.13.670175

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