Researcher

My Expertise

My research investigates the genetic and transcriptomic changes associated with brain disorders, including neurodevelopmental and neurodegenerative disorders, and their underlying mechanisms. 

Keywords

Fields of Research (FoR)

Neurogenetics, Genomics, Animal cell and molecular biology

Biography

My PhD research investigated enhancers, which are non-coding genetic regulatory regions, in primary human astrocytes, a glial cell subtype in the brain. Enhancers harbour mutations for complex diseases, such as neurodevelopmental and neurodegenerative disorders, and often act in a cell-type specific manner. While enhancers and the genes they regulate can be predicted by biochemical signatures, many candidate enhancers do not act as enhancers...view more

Location

Level 3, Biological Sciences (E26)

Publications

by Dr Nicole Green