Keywords
Fields of Research (FoR)
Immunology, Virology, Immunogenetics (incl. genetic immunology), Cancer therapy (excl. chemotherapy and radiation therapy)Biography
David is a post-doctoral research scientist investigating the co-morbidities of viral infection. His primary interests are quantifying immune traits that lead to disease and quantifying how people react to pathogens including human immunodeficiency virus (HIV-1), papillomavirus (HPV) and tuberculosis either during natural infection or undergoing treatment.
My Grants
October (2024): Untangling the inherited and acquired host...view more
David is a post-doctoral research scientist investigating the co-morbidities of viral infection. His primary interests are quantifying immune traits that lead to disease and quantifying how people react to pathogens including human immunodeficiency virus (HIV-1), papillomavirus (HPV) and tuberculosis either during natural infection or undergoing treatment.
My Grants
October (2024): Untangling the inherited and acquired host determinants predicting progression and persistence of HPV-driven anal disease (St Vincent's Clinic Foundation Research Grant) - $50,000
October (2023): Assessment of proviral reservoir characteristics in early HIV infection (St Vincent's Clinic Foundation Research Grant) - $50,000
December (2021): Characterisation and therapeutic harnessing of CD8+ tissue resident memory T (TRM) cell response to high-risk human papillomavirus (HPV)-associated anal squamous intraepithelial lesions (SIL) in the setting of human immunodeficiency virus (HIV) co-infection (National Institutes of Health (NIH), Notification of Special Interest R21 grant) - $450,000AUD
My Qualifications
Bachelor of Biotechnology (Hons), PhD (St Vincent's Clinical School)
My Research Activities
Fundamental basic research and clinical application to address the effect of standard treatment and experimental immunotherapies for infections (and vaccinations) including HPV, HIV and tuberculosis. Extensive experience in the field of immunovirology, lead in the development and completion of multiple national/international clinical trial projects requiring precise laboratory investigations.
My Research Supervision
Supervision keywords
Areas of supervision
Supervision is available for HDR candidates through medical disciplines that include immunology, virology and translational clinical trial research. I have supervised candidates to the completion of PhD and honours programmes, through laboratory based studies and subequent analysis programmes. Areas where I am able to provide supervision to investigate the immunopathogenesis of pathogens include human immunodeficiency virus (HIV-1), human papillomavirus (HPV), tuberculosis and SARS-CoV-2. Specific streams of research within these models include natural history studies, application of immuno- and small-molecule therapies to treat the course of disease as well as treatment options for comorbidities generated as a result of infection.
Currently supervising
Currently, I am supervising an HDR candidate to completion within a programme to understand the determinants of HIV-1 viral reservoir dissemination during early and chronic infection. The model tested is testing the effect of integrase-inhibitor (INSTI) therapy upon seeding of the HIV-1 reservoir in treatment naïve participants.
Location
Publications
ORCID as entered in ROS
https://orcid.org/0000-0003-0048-5813