Biography
I am a Senior Research Fellow who transitioned from a decade of laboratory-based cardiovascular and cancer gene therapy research into clinical research. My PhD work was published in Nature Communications, with additional review articles in Lancet eBiomedicine, Advanced Functional Materials, and ACS Nano AU.
I was the project manager for the Hospital in the Home for Hip Fracture project at Liverpool Hospital, which was named a 2025 SWSLHD...view more
I am a Senior Research Fellow who transitioned from a decade of laboratory-based cardiovascular and cancer gene therapy research into clinical research. My PhD work was published in Nature Communications, with additional review articles in Lancet eBiomedicine, Advanced Functional Materials, and ACS Nano AU.
I was the project manager for the Hospital in the Home for Hip Fracture project at Liverpool Hospital, which was named a 2025 SWSLHD Quality Awards Finalist for Health Research. I now lead the "Rehabilitation in the Home" randomised controlled trial for hip fracture patients at Liverpool and Bankstown-Lidcombe Hospitals, where I coordinate multidisciplinary teams and oversee data analysis.
I also have extensive experience in community engagement, particularly with culturally and linguistically diverse populations in South West Sydney.
My Grants
Rehabilitation in the home (RITH) after hip fracture: right care, right time, right place, right choice (RITH4Hips) - HCF 2024 Health Services Research Grant Program - AUD $493,233.00
My Qualifications
BSc Biomedical Sciences - University of Manchester, UK
Doctor of Philosophy (PhD) in Physiology - University of Manchester, UK
Graduate Certificate in Higher Education Teaching and Learning, University of Technology Sydney
My Awards
SWSLHD Quality Awards Finalists in Health Research, 2025
President’s Doctoral Scholar Award, University of Manchester, UK, 2014-2018
Award for Excellence, Faculty of Life Sciences, University of Manchester, UK 2014
Outstanding Achievement Award, Faculty of Life Sciences, University of Manchester, UK, 2012
Silver Medal - 21st International Biology Olympiad 2010
First Prize - National Biology Olympiad, Vietnam 2010
My Research Activities
1. Bui, T.A*., Lestari, B.*, Nugroho, A.B.*, Nguyen, B., Stafford, N., Prehar, S., Zi, M., Potter, R. Triastuti, E., Baudoin, F.M., D’Souza, A., Wang, X., Cartwright, E.J, Oceandy, D. Nature Communications. 2025, 16, 1650
2. Naylor, J.M., Bùi, T.A., Frost, S., et al. Foundations for Developing a Hospital in the Home Pathway Following Low Trauma Hip Fracture: Using Data to Inform the Path. Home Health Care Management & Practice. 2025, 0, 0.
3. Wang, Y., Bui, T.A., Yang, X. et al. Advancements in gene therapies targeting mutant KRAS in cancers. Cancer Metastasis Rev. 2025; 44, 24
4. Bui, T.A.; Mei, H.; Sang, R.; Ortega, D.G.; Deng, W. Advancements and challenges in developing in vivo CAR T cell therapies for cancer treatment. EBioMedicine 2024, 106, 105266.
5. Bui, T.A.; Yang, X.; Mei, H.; Aksoy, Y.A.; Deng,F.; Hutvagner, G.; Deng., W. Exploring the Potential and Challenges of CRISPR Delivery and Therapeutics for Genetic Disease Treatment. Advanced Functional Materials 2024, 2402630.
6. Mehta, M.; Bui, T.A.;Care, A.; Deng, W. Targeted polymer lipid hybrid nanoparticles for in-vitro siRNA therapy in triple-negative breast cancer. Journal of Drug Delivery Science and Technology 2024, 98, 105911
7. Bui, T. A.; Stafford, N.; Oceandy, D., Genetic and Pharmacological YAP Activation Induces Proliferation and Improves Survival in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cells 2023, 12, 7.
8. Mehta, M.; Bui, T.A.;Yang, X.; Aksoy, Y.; Goldys, E. M.; Deng, W., Lipid-Based Nanoparticles for Drug/Gene Delivery: An Overview of the Production Techniques and Difficulties Encountered in Their Industrial Development. ACS Materials Au 2023.
9. Nugroho, A. B.; Stafford, N.;Zi, M.; Prehar,S.; Potter, R.;Kwon,D.; Kohar, Y. S.; Triastuti, E.; Bui,T. A.;Cartwright, E. J.; Oceandy, D., Micro RNA-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice. JACC Basic Transl Sci 2022, 7 (9), 859-875.
10. Pawitan, J. A.; Bui, T. A.;Mubarok, W.; Antarianto, R. D.; Nurhayati, R. W.; Dilogo, I. H.; Oceandy, D., Enhancement of the Therapeutic Capacity of Mesenchymal Stem Cells by Genetic Modification: A Systematic Review. Front Cell Dev Biol 2020,8, 587776.
11. Nguyen, B. Y.; Ruiz-Velasco, A.; Bui, T.;Collins, L.; Wang, X.; Liu, W., Mitochondrial function in the heart: the insight into mechanisms and therapeutic potentials. Br J Pharmacol 2019,176 (22), 4302-4318.
12. Triastuti, E.; Nugroho, A. B.; Zi, M.;Prehar, S.; Kohar, Y. S.; Bui, T.A.;Stafford, N.; Cartwright, E. J.; Abraham, S.; Oceandy, D., Pharmacological inhibition of Hippo pathway, with the novel kinase inhibitor XMU-MP-1, protects the heart against adverse effects during pressure overload. Br J Pharmacol 2019, 176 (20), 3956-3971.
13. Zi, M.;Stafford, N.; Prehar, S.; Baudoin, F.;Oceandy, D.; Wang, X.; Bui, T.;Shaheen, M.; Neyses, L.; Cartwright, E. J., Cardiac hypertrophy or failure? - A systematic evaluation of the transverse aortic constriction model in C57BL/6NTac and C57BL/6J substrains. Curr Res Physiol 2019,1, 1-10.
14. Robertson, A.; Mohamed, T. M.; El Maadawi, Z.; Stafford, N.; Bui, T.; Lim, D. S.; Cartwright, E. J.; Oceandy, D., Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival. Stem Cell Res 2017,20, 42-49
My Research Supervision
Supervision keywords
Areas of supervision
Available to supervise ILP, Honours, Master, and PhD students in:
-
Clinical trials in rehabilitation and musculoskeletal health
-
Health service research for culturally and linguistically diverse populations
-
Translational research bridging laboratory innovation to clinical application