By Professor Michelle Haber

Journal articles

Lau DT; Hesson LB; Norris MD; Haber M; Marshall GM; Ashton LJ, 2012, 'Prognostic significance of promoter DNA methylation in patients with neuroblastoma', CANCER RESEARCH, 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1425

Venn NC; Van der velden VHJ; De bie M; Waanders E; Giles JE; Law T; Kuiper RP; de Haas V; Mullighan CG; Haber M; Marshall GM; Norris MD; Van dongen JJM; Sutton R; Giles J; Law T, 2012, 'Highly sensitive MRD tests for ALL based on the IKZF1 Delta 3-6 microdeletion', Leukemia, 26, pp. 1414 - 1416, http://dx.doi.org/10.1038/leu.2011.348

Chenevix-Trench G; Lu Y; Johnatty S; Gamazon E; Beesley J; Chen X; Gao B; Harnett P; Stephanie Huang R; Despierre E; Heitz F; Hogdall E; Hogdall C; Brown R; Moyisch K; Fasching P; Goode E; Russell A; Henderson M; Haber M; Dolan E; Macgregor S; deFazio A, 2012, 'Identification of a genetic variant associated with treatment outcome in ovarian cancer: the potential role of cholesterol metabolism as a determinant of response to chemotherapy', Hereditary cancer in clinical practice, 10, pp. A36 - A36, http://dx.doi.org/10.1186/1897-4287-10-s2-a36

Fletcher JI; Gherardi S; Murray J; Burkhart C; Russell A; Valli E; Smith J; Oberthuer A; Ashton LJ; London WB; Marshall GM; Norris MD; Perini G; Haber M, 2012, 'N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma', Cancer Research, 72, pp. 845 - 853, http://dx.doi.org/10.1158/0008-5472.CAN-11-1885

Carpinteri S, 2012, 'Optimizing DNA Vaccines Against Nuclear Oncogenes', ImmunoGastroenterology, 1, pp. 108 - 108, http://dx.doi.org/10.7178/ig.19

Gamble LD; Hogarty MD; Liu X; Ziegler DS; Marshall GM; Norris MD; Haber M; Gamble L, 2012, 'Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma', Frontiers in Oncology, 2, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2012.00162

Lau DT; Hesson L; Norris MD; Marshall GM; Haber M; Ashton LJ, 2012, 'Prognostic Significance of Promoter DNA Methylation in Patients with Childhood Neuroblastoma', Clinical Cancer Research, 18, pp. 5690 - 5700, http://dx.doi.org/10.1158/1078-0432.CCR-12-0294

Schleiermacher G; Mosseri V; London WB; Maris JM; Brodeur GM; Attiyeh E; Haber M; Khan J; Nakagawara A; Speleman F; Noguera R; Tonini GP; Fischer M; Ambros I; Monclair T; Matthay KK; Ambros P; Cohn SL; Pearson ADJ, 2012, 'Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project', British Journal of Cancer, 107, pp. 1418 - 1422, http://dx.doi.org/10.1038/bjc.2012.375

Keating J; Tsoli M; Hallahan AR; Ingram WJ; Haber M; Ziegler DS, 2012, 'Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma', Molecular Cancer Therapeutics, 11, pp. 2654 - 2663, http://dx.doi.org/10.1158/1535-7163.MCT-12-0352

Cheung BB; Koach J; Tan O; Kim P; Bell J; D'andreti C; Sutton S; Malyukova A; Sekyere E; Norris MD; Haber M; Kavallaris M; Cunningham AM; Proby C; Leigh I; Wilmott J; Cooper C; Halliday GM; Scolyer RA; Marshall GM, 2012, 'The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro', Journal of Pathology, 226, pp. 451 - 462, http://dx.doi.org/10.1002/path.2986

Bailey HD; Armstrong BK; de Klerk NH; Fritschi L; Attia J; Scott RJ; Smibert E; Milne E, 2011, 'Exposure to professional pest control treatments and the risk of childhood acute lymphoblastic leukemia', INTERNATIONAL JOURNAL OF CANCER, 129, pp. 1678 - 1688, http://dx.doi.org/10.1002/ijc.25769

Bailey HD; Milne E; de Klerk NH; Fritschi L; Attia J; Cole C; Armstrong BK, 2011, 'Exposure to house painting and the use of floor treatments and the risk of childhood acute lymphoblastic leukemia', INTERNATIONAL JOURNAL OF CANCER, 128, pp. 2405 - 2414, http://dx.doi.org/10.1002/ijc.25572

Milne E; Royle JA; Bennett LC; de Klerk NH; Bailey HD; Bower C; Miller M; Attia J; Scott RJ; Kirby M; Armstrong BK, 2011, 'Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: results from an Australian case-control study', CANCER CAUSES & CONTROL, 22, pp. 207 - 218, http://dx.doi.org/10.1007/s10552-010-9688-1

Henderson M; Haber M; Porro A; Munoz M; Xue C; Murray JE; Flemming C; Smith J; Fletcher JI; Gherardi S; Kwek C; Russell AJ; Valli E; London WB; Buxton AB; Ashton LJ; Sartorelli AC; Cohn SL; Schwab M; Marshall GM; Perini G; Norris MD; Kwek C-K, 2011, 'ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux', Journal of the National Cancer Institute, 103, pp. 1236 - 1251, http://dx.doi.org/10.1093/jnci/djr256

Pajic M; Murray JE; Marshall GM; Cole SPC; Norris MD; Haber M, 2011, 'ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript', Pharmacogenetics and Genomics, 21, pp. 270 - 279, http://dx.doi.org/10.1097/FPC.00b013e328343dd5f

Porro A; Iraci N; Soverini S; Diolaiti D; Gherardi S; Terragna C; Durante S; Valli E; Kalebic T; Bernardoni R; Perrod C; Haber M; Norris MD; Baccarani M; Martinelli G; Perini G, 2011, 'c-MYC Oncoprotein Dictates Transcriptional Profiles of ATP-Binding Cassette Transporter Genes in Chronic Myelogenous Leukemia CD34(+) Hematopoietic Progenitor Cells', Molecular Cancer Research, 9, pp. 1054 - 1066, http://dx.doi.org/10.1158/1541-7786.MCR-10-0510

Lau DTT; Norris MD; Marshall GM; Haber M; Ashton LJ, 2011, 'HLA-G polymorphisms, genetic susceptibility, and clinical outcome in chidlhood neuroblastoma', Tissue Antigens, 78, pp. 421 - 427, http://dx.doi.org/10.1111/j.1399-0039.2011.01781.x

Marshall GM; Liu PY; Gherardi S; Scarlett CJ; Bedalov A; Xu N; Iraci N; Valli E; Ling D; Thomas W; Van bekkum M; Sekyere E; Jankowski K; Trahair T; Mackenzie K; Haber M; Norris MD; Biankin AV; Perini G; Liu T, 2011, 'SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability', PLOS Genetics, 7, pp. e1 - e14, http://dx.doi.org/10.1371/journal.pgen.1002135

Fletcher JI; Haber M; Henderson M; Norris MD, 2010, 'ABC transporters in cancer: more than just drug efflux pumps', Nature Reviews Cancer, 10, pp. 147 - 156, http://dx.doi.org/10.1038/nrc2789

Porro A; Haber M; Diolaiti D; Iraci N; Henderson M; Gherardi S; Valli E; Munoz M; Xue C; Flemming C; Schwab M; Wong JH; Marshall GM; Della valle G; Norris MD; Perini G, 2010, 'Direct and Coordinate Regulation of ATP-binding Cassette Transporter Genes by Myc Factors Generates Specific Transcription Signatures That Significantly Affect the Chemoresistance Phenotype of Cancer Cells', The Journal of Biological Chemistry, 285, pp. 19532 - 19543, http://dx.doi.org/10.1074/jbc.M109.078584

Bhadri V; McGregor MR; Venn NC; Hackenberg N; Russell SJ; Norris MD; Haber M; Sutton R; Marshall GM, 2010, 'Isolated testicular relapse after allo-SCT in boys with ALL: outcome without second transplant', Bone Marrow Transplantation, 45, pp. 397 - 399, http://dx.doi.org/10.1038/bmt.2009.138

Milne E; Royle JA; Miller M; Bower C; de klerk NH; Bailey HD; Van brockxmeer F; Attia J; Scott RJ; Norris MD; Haber M; Thompson JR; Fritschi L; Marshall GM; Armstrong B, 2010, 'Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspring', International Journal of Cancer, 126, pp. 2690 - 2699, http://dx.doi.org/10.1002/ijc.24969

Swarbrick A; Woods SL; Shaw A; Balakrishnan A; Phua Y; Nguyen A; Chanthery Y; Lim L; Ashton LJ; Judson RL; Blelloch R; Huskey N; Haber M; Norris MD; Lengyel P; Hackett CS; Preiss T; Chetcuti A; Sullivan CS; Marcusson EG; Weiss W; L''Etoile N; Goga A, 2010, 'miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma', Nature Medicine, 16, pp. 1134 - 1141, http://dx.doi.org/10.1038/nm.2227

Liu T, 2010, 'Opposing Effects of Two Tissue Transglutaminase Protein Isoforms in Neuroblastoma Cell Differentiation', The Journal of Biological Chemistry, 285, pp. 3561 - 3567, http://dx.doi.org/10.1074/jbc.M109.053041

Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair TN; Scarlett CJ; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Keating J; Sekyere E; Jonquieres G; Biankin AV; Stossi F; Katzenellenbogen BS; Perini G; Liu T, 2010, 'Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', Oncogene, 29, pp. 5957 - 5968, http://dx.doi.org/10.1038/onc.2010.332

Liu T; Bell J; Koach J; Malyukova A; Thomas W; Sekyere E; Cunningham A; Norris M; Haber M; Kavallaris M; Cheung B-B; Kim P; Tan O; marshall G, 2010, 'TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells', Oncogene, 29, pp. 6172 - 6183, http://dx.doi.org/10.1038/onc.2010.340

Bohlken A; Cheung B; Bell J; Koach J; Smith S; Sekyere E; Thomas WD; Norris MD; Haber M; Lovejoy DB; Richardson DR; Marshall GM, 2009, 'ATP7A is a novel target of retinoic acid receptor beta(2) in neuroblastoma cells', British Journal of Cancer, 100, pp. 96 - 105, http://dx.doi.org/10.1038/sj.bjc.6604833

Sutton R; Venn NC; Tolisano J; Bahar AY; Giles JE; Ashton LJ; Teague L; Rigutto G; Waters K; Marshall GM; Haber M; Norris MD; Giles J, 2009, 'Clinical significance of minimal residual disease at day 15 and at the end of therapy in childhood acute lymphoblastic leukaemia', British Journal of Haematology, 146, pp. 292 - 299, http://dx.doi.org/10.1111/j.1365-2141.2009.07744.x

Brisco MJ; Latham S; Sutton R; Hughes E; Wilczek V; Van Zanten K; Budgen B; Malec M; Sykes PJ; Kuss BJ; Waters K; Venn NC; Giles J; Haber M; Norris MD; Marshall GM; Morley AA; Bahar ; Giles J, 2009, 'Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia', Journal of Molecular Diagnostics, 11, pp. 194 - 200, http://dx.doi.org/10.2353/jmoldx.2009.080047

Ambros PF; Ambros IM; Brodeur GM; Haber M; Khan J; Nakagawara A; Schleiermacher G; Speleman F; Spitz R; London WB; Cohn SL; Pearson ADJ; Maris JM, 2009, 'International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee', British Journal of Cancer, 100, pp. 1471 - 1482, http://dx.doi.org/10.1038/sj.bjc.6605014

Ambros PF; Ambros IM; Brodeur GM; Haber M; Khan J; Nakagawara A; Schleiermacher G; Speleman F; Spitz R; London WB; Cohn SL; Pearson ADJ; Maris JM, 2009, 'International consensus for neuroblastoma molecular diagnostics: Report from the international neuroblastoma risk grouping (INRG) Biology committee', Klinische Pädiatrie, 221, http://dx.doi.org/10.1055/s-0029-1222622

Dilda P; Decollogne SM; Weerakoon L; Norris MD; Haber M; Allen JD; Hogg PJ, 2009, 'Optimization of the antitumor efficacy of a synthetic mitochondrial toxin by increasing the residence time in the cytosol', Journal of Medicinal Chemistry, 52, pp. 6209 - 6216, http://dx.doi.org/10.1021/jm9008339

Liu T, 2009, 'Over-expression of clusterin is a resistance factor to the anti-cancer effect of histone deacetylase inhibitors', European Journal of Cancer, 45, pp. 1846 - 1854, http://dx.doi.org/10.1016/j.ejca.2009.03.002

Thomas WD; Chen J; Gao YR; Cheung BB; Koach J; Sekyere E; Norris MD; Haber M; Ellis T; Wainwright B; Marshall GM, 2009, 'Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression', Oncogene, 28, pp. 1605 - 1615, http://dx.doi.org/10.1038/onc.2009.3

Ashton LJ; Gifford AJ; Kwan E; Lingwood A; Lau DTT; Marshall GM; Haber M; Norris MD, 2009, 'Reduced folate carrier and methylenetetrahydrofolate reductase gene polymorphisms: associations with clinical outcome in childhood acute lymphoblastic leukemia', Leukemia, 23, pp. 1348 - 1351, http://dx.doi.org/10.1038/leu.2009.67

Burkhart CA; Watt F; Murray J; Pajic M; Prokvolit A; Xue C; Flemming C; Smith J; Purmal A; Isachenko N; Komarov PG; Gurova KV; Sartorelli AC; Marshall GM; Norris MD; Gudkov AV; Haber M, 2009, 'Small-Molecule Multidrug Resistance-Associated Protein 1 Inhibitor Reversan Increases the Therapeutic Index of Chemotherapy in Mouse Models of Neuroblastoma', Cancer research, 69, pp. 6573 - 6580, http://dx.doi.org/10.1158/0008-5472.CAN-09-1075

Liu T, 2009, 'The cyclin-dependent kinase inhibitor, p21WAF1, promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells', Carcinogenesis, 30, pp. 1865 - 1871, http://dx.doi.org/10.1093/carcin/bgp225

Raif A; Marshall GM; Bell J; Koach J; Tan O; D'andreti C; Thomas WD; Sekyere E; Norris MD; Haber M; Kavallaris M; Cheung BB, 2009, 'The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation', Cancer Letters, 277, pp. 82 - 90, http://dx.doi.org/10.1016/j.canlet.2008.11.030

Henderson M; Choi S; Beesley A; Baker DL; Wright DC; Papa R; Murch A; Campbell L; Lock RB; Norris MD; Haber M; Kees UR, 2008, 'A xenograft model of infant leukaemia reveals a complex MLL translocation', British Journal of Haematology, 140, pp. 716 - 719, http://dx.doi.org/10.1111/j.1365-2141.2007.06966.x

Sutton R; Kwan EN; Giles JE; Venn NC; Tran S; Hackenberg N; Dalla Pozza L; Marshall GM; Haber M; van der Velden V; Norris MD; Bahar ; Giles J, 2008, 'Improving minimal residual disease detection in precursor B-ALL based on immunoglobulin-j and heavy-chain gene rearrangements', Leukemia, 22, pp. 2265 - 2267

Williams BB; Wall M; Miao RY; Williams B; Bertoncello I; Kershaw MH; Mantamadiotis T; Haber M; Norris MD; Gautam A; Darcy PK; Ramsay RG, 2008, 'Induction of T cell-mediated immunity using a c-Myb DNA vaccine in a mouse model of colon cancer', Cancer Immunology and Immunotherapy, 57, pp. 1635 - 1645

Smith DJ; Cossins LR; Hatzinisiriou I; Haber M; Nagley P, 2008, 'Lack of correlation between MYCN expression and the Warburg effect in neuroblastoma cell lines.', BMC Cancer, 8, pp. 259, http://dx.doi.org/10.1186/1471-2407-8-251

Henderson M; Choi S; Beesley A; Sutton R; Venn NC; Marshall GM; Kees UR; Haber M; Norris MD, 2008, 'Mechanism of relapse in pediatric acute lymphoblastic leukemia', Cell Cycle, 7, pp. 1315 - 1320

Hogarty MD; Norris MD; Davis K; Liu X; Evangeliou NF; Hayes CS; Pawel B; Guo R; Zhao H; Sekyere E; Keating J; Thomas WD; Cheng NC; Murray JE; Smith J; Sutton R; Venn NC; London WB; Buxton A; Gilmour SK; Marshall GM; Haber M, 2008, 'ODC1 Is a Critical Determinant of MYCN Oncogenesis and a Therapeutic Target in Neuroblastoma', Cancer research, 68, pp. 9735 - 9745

Sutton R; Lonergan MA; Tapp H; Venn NC; Haber M; O Brien T; Alvaro F; Revesz T; Norris MD, 2008, 'Two cases of hypereosinophilia and high-risk acute lymphoblastic leukemia', Leukemia, 22, pp. 1463 - 1465

Liu T; Tee AEL; Porro A; Smith SA; Dwarte T; Pei YL; Iraci N; Sekyere E; Haber M; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (Proceedings of the National Academy of Science of the United States of America (November 20, 2007) 104; 47, (18682-18687) DOI: 10.1073/pnas.0705524104)', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 21021, http://dx.doi.org/10.1073/pnas.0711060105

Liu T; Tee EL; Porro A; Smith SA; Dwarte T; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (vol 104, pg 18682, 2007)', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104, pp. 21021 - 21021, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000252077400076&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Liu T; Tee AEL; Porro A; Smith SA; Dwarte T; Pei YL; Iraci N; Sekyere E; Haber M; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM, 2007, 'Erratum: Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (Proceedings of the National Academy of Sciences of the United States of America (2007) 104 (18682-18687) DOI: 10.1073/pnas.0705524104)', Proceedings of the National Academy of Sciences of the United States of America, 120, http://dx.doi.org/10.1073/pnas.2220015120

Ambros PF; Ambros IM; Brodeur GM; Haber M; Khan J; Nakagawara A; Schleiermacher G; Speleman F; Spitz R; Maris JM, 2007, 'International consensus for neuroblastoma molecular diagnostics: report from the international neuroblastoma risk grouping (INRG) biology committee', EJC SUPPLEMENTS, 5, pp. 48 - 48, http://dx.doi.org/10.1016/S1359-6349(07)70295-1

Norris MD; Smith J; Kwek A; Flemming C; Cohn SL; London WB; Buxton A; Marshall GM; Haber M, 2007, 'Expression of the multidrug transporter genes ABCC1/MRP1, ABCC3/MRP3, and ABCC4/MRP4 are powerful predictors of clinical outcome in childhood neuroblastoma', Journal of Clinical Oncology, 25, pp. 9524 - 9524, http://dx.doi.org/10.1200/jco.2007.25.18_suppl.9524

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