By Professor Kate Louise Seib

Journal articles

Williams E; Low SJ; Pollock GL; Taouk ML; Prestedge J; Howden BP; Chow EPF; Fairley CK; Seib KL; McCarthy JS; Pasricha S; Williamson DA, 2025, 'Selecting candidate Neisseria gonorrhoeae strains for oropharyngeal gonorrhoea human challenge: a genomics-based analysis of clinical isolates', Lancet Microbe, 6, http://dx.doi.org/10.1016/j.lanmic.2025.101105

Ryan FJ; Clarke M; Lynn MA; Benson SC; McAlister S; Giles LC; Choo JM; Rossouw C; Ng YY; Semchenko EA; Richard A; Leong LEX; Taylor SL; Blake SJ; Mugabushaka JI; Walker M; Wesselingh SL; Licciardi PV; Seib KL; Tumes DJ; Richmond P; Rogers GB; Marshall HS; Lynn DJ, 2025, 'Bifidobacteria support optimal infant vaccine responses', Nature, 641, pp. 456 - 464, http://dx.doi.org/10.1038/s41586-025-08796-4

Ong JJ; Unemo M; Molina JM; Miranda AE; Seib KL; Brito de Mello M; Doherty M; Johnson CC; Delany-Moretlwe S; Fairley C, 2025, 'Beyond behavioural change: prioritising structural solutions to control bacterial sexually transmitted infections', Eclinicalmedicine, 83, http://dx.doi.org/10.1016/j.eclinm.2025.103198

Ngoo A; Semchenko EA; Atack A; Thomas PB; Seib KL; Vela I; Williams ED, 2025, 'Could Neisseria gonorrhoeae have carcinogenic potential? A critical review of current evidence', Critical Reviews in Microbiology, http://dx.doi.org/10.1080/1040841X.2024.2448166

Taha ; Eskandari S; Slesarenko VA; Haselhorst T; Semchenko EA; Seib KL, 2024, 'Refinement and optimisation of Neisseria gonorrhoeae NHBA and MetQ vaccine candidates', Vaccine, 42, http://dx.doi.org/10.1016/j.vaccine.2024.126416

Chow EPF; Stevens K; De Petra V; Chen MY; Bradshaw CS; Sherry NL; Barbee LA; Vodstrcil LA; Aguirre I; Seib KL; Maddaford K; Williamson DA; Howden BP; Fairley CK, 2024, 'Prevalence of Cefixime-Resistant Neisseria gonorrhoeae in Melbourne, Australia, 2021-2022', Journal of Infectious Diseases, 230, pp. e1121 - e1125, http://dx.doi.org/10.1093/infdis/jiae313

Gottlieb SL; Spielman E; Abu-Raddad L; Aderoba AK; Bachmann LH; Blondeel K; Chen XS; Crucitti T; Camacho GG; Godbole S; de Leon RGP; Gupta S; Hermez J; Ishikawa N; Klausner JD; Kurbonov F; Maatouk I; Mandil A; Mello MB; Miranda AE; Mosha FS; Okeibunor JC; Ong JJ; Peters RPH; Pérez F; Seguy N; Seib KL; Sharma M; Sladden T; Van Der Pol B; White PJ; Wi T; Broutet N, 2024, 'WHO global research priorities for sexually transmitted infections', Lancet Global Health, 12, pp. e1544 - e1551, http://dx.doi.org/10.1016/S2214-109X(24)00266-3

Wang B; Seib KL; Marshall H, 2024, 'The future role of vaccination in prevention of Neisseria gonorrhoeae', Microbiology Australia, 45, pp. 117 - 121, http://dx.doi.org/10.1071/MA24034

Padeniya TN; Hui BB; Wood JG; Regan DG; Seib KL, 2024, 'Review of mathematical models of Neisseria gonorrhoeae vaccine impact: Implications for vaccine development', Vaccine, 42, pp. S70 - S81, http://dx.doi.org/10.1016/j.vaccine.2024.03.068

Lyu Y; Choong A; Chow EPF; Seib KL; Marshall HS; Unemo M; de Voux A; Wang B; Miranda AE; Gottlieb SL; Mello MB; Wi T; Baggaley R; Marshall C; Abu-Raddad LJ; Abara WE; Chen XS; Ong JJ, 2024, 'Vaccine value profile for Neisseria gonorrhoeae', Vaccine, 42, pp. S42 - S69, http://dx.doi.org/10.1016/j.vaccine.2023.01.053

Seib KL; Donovan B; Thng C; Lewis DA; McNulty A; Fairley CK; Yeung B; Jin F; Fraser D; Bavinton BR; Law M; Chen MY; Chow EPF; Whiley DM; Mackie B; Jennings MP; Jennison AV; Lahra MM; Grulich AE, 2024, 'Multicentre double-blind randomised placebo-controlled trial evaluating the efficacy of the meningococcal B vaccine, 4CMenB (Bexsero), against Neisseria gonorrhoeae infection in men who have sex with men: the GoGoVax study protocol', BMJ Open, 14, http://dx.doi.org/10.1136/bmjopen-2023-081675

Williams E; Seib KL; Fairley CK; Pollock GL; Hocking JS; McCarthy JS; Williamson DA, 2024, 'Neisseria gonorrhoeae vaccines: a contemporary overview', Clinical Microbiology Reviews, 37, http://dx.doi.org/10.1128/cmr.00094-23

Thng C; Semchenko EA; Hughes I; O’Sullivan M; Seib KL, 2023, 'An open-label randomised controlled trial evaluating the efficacy of a meningococcal serogroup B (4CMenB) vaccine on Neisseria gonorrhoeae infection in gay and bisexual men: the MenGO study protocol', BMC Public Health, 23, http://dx.doi.org/10.1186/s12889-023-15516-y

Padeniya TN; Hui BB; Wood JG; Seib KL; Regan DG, 2023, 'The potential impact of a vaccine on Neisseria gonorrhoeae prevalence among heterosexuals living in a high prevalence setting', Vaccine, 41, pp. 5553 - 5561, http://dx.doi.org/10.1016/j.vaccine.2023.07.048

Branch AH; Stoudenmire JL; Seib KL; Cornelissen CN, 2022, 'Acclimation to Nutritional Immunity and Metal Intoxication Requires Zinc, Manganese, and Copper Homeostasis in the Pathogenic Neisseriae', Frontiers in Cellular and Infection Microbiology, 12, http://dx.doi.org/10.3389/fcimb.2022.909888

Hui BB; Padeniya TN; Rebuli N; Gray RT; Wood JG; Donovan B; Duan Q; Guy R; Hocking JS; Lahra MM; Lewis DA; Whiley DM; Regan DG; Seib KL, 2022, 'A Gonococcal Vaccine Has the Potential to Rapidly Reduce the Incidence of Neisseria gonorrhoeae Infection among Urban Men Who Have Sex with Men', Journal of Infectious Diseases, 225, pp. 983 - 993, http://dx.doi.org/10.1093/infdis/jiab581

Semchenko EA; Seib KL, 2022, 'Outer membrane vesicle vaccines for Neisseria gonorrhoeae', Nature Reviews Urology, 19, pp. 5 - 6, http://dx.doi.org/10.1038/s41585-021-00534-5

Evert BJ; Slesarenko VA; Punnasseril JMJ; Taha ; Zhan J; Zhou Y; Semchenko EA; Seib KL, 2022, 'Self-Inhibitory Peptides Targeting the Neisseria gonorrhoeae MtrCDE Efflux Pump Increase Antibiotic Susceptibility', Antimicrobial Agents and Chemotherapy, 66, http://dx.doi.org/10.1128/AAC.01542-21

Ruiz García Y; Sohn WY; Seib KL; Taha MK; Vázquez JA; de Lemos APS; Vadivelu K; Pizza M; Rappuoli R; Bekkat-Berkani R, 2021, 'Looking beyond meningococcal B with the 4CMenB vaccine: the Neisseria effect', Npj Vaccines, 6, http://dx.doi.org/10.1038/s41541-021-00388-3

Jen FEC; Ketterer MR; Semchenko EA; Day CJ; Jennings MP; Seib KL; Apicella MA, 2021, 'The lst sialyltransferase of neisseria gonorrhoeae can transfer keto-deoxyoctanoate as the terminal sugar of lipooligosaccharide: A glyco-achilles heel that provides a new strategy for vaccines to prevent gonorrhea', Mbio, 12, http://dx.doi.org/10.1128/mBio.03666-20

Semchenko EA; Chen X; Thng C; O’Sullivan M; Seib KL, 2020, 'Gonorrhoea: past, present and future', Microbiology Australia, 41, pp. 205 - 209, http://dx.doi.org/10.1071/ma20055

Jen FEC; Scott AL; Tan A; Seib KL; Jennings MP, 2020, 'Random Switching of the ModA11 Type III DNA Methyltransferase of Neisseria meningitidis Regulates Entner–Doudoroff Aldolase Expression by a Methylation Change in the eda Promoter Region', Journal of Molecular Biology, 432, pp. 5835 - 5842, http://dx.doi.org/10.1016/j.jmb.2020.08.024

Seib KL; Srikhanta YN; Atack JM; Jennings MP, 2020, 'Epigenetic Regulation of Virulence and Immunoevasion by Phase-Variable Restriction-Modification Systems in Bacterial Pathogens', Annual Review of Microbiology, 74, pp. 655 - 671, http://dx.doi.org/10.1146/annurev-micro-090817-062346

Gottlieb SL; Ndowa F; Hook EW; Deal C; Bachmann L; Abu-Raddad L; Chen XS; Jerse A; Low N; MacLennan CA; Petousis-Harris H; Seib KL; Unemo M; Vincent L; Giersing BK, 2020, 'Gonococcal vaccines: Public health value and preferred product characteristics; report of a WHO global stakeholder consultation, January 2019', Vaccine, 38, pp. 4362 - 4373, http://dx.doi.org/10.1016/j.vaccine.2020.02.073

Tan A; Blakeway LV; Taha ; Yang Y; Zhou Y; Atack JM; Peak IR; Seib KL, 2020, 'Moraxella catarrhalis phase-variable loci show differences in expression during conditions relevant to disease', Plos One, 15, http://dx.doi.org/10.1371/journal.pone.0234306

Semchenko EA; Day CJ; Seib KL, 2020, 'The neisseria gonorrhoeae vaccine candidate nhba elicits antibodies that are bactericidal, opsonophagocytic and that reduce gonococcal adherence to epithelial cells', Vaccines, 8, http://dx.doi.org/10.3390/vaccines8020219

Semchenko EA; Mubaiwa TD; Day CJ; Seib KL, 2020, 'Role of the Gonococcal Neisserial Heparin Binding Antigen in Microcolony Formation, and Serum Resistance and Adherence to Epithelial Cells', Journal of Infectious Diseases, 221, pp. 1612 - 1622, http://dx.doi.org/10.1093/infdis/jiz628

Blakeway LV; Tan A; Peak IR; Atack JM; Seib KL, 2020, 'Transcriptome RNA sequencing data set of gene expression in moraxella catarrhalis on- And off-phase variants of the type III DNA methyltransferase ModM3', Microbiology Resource Announcements, 9, http://dx.doi.org/10.1128/MRA.01559-19

Blakeway LV; Tan A; Peak IR; Atack JM; Seib KL, 2020, 'Proteome of a Moraxella catarrhalis Strain under Iron-Restricted Conditions', Microbiology Resource Announcements, 9, http://dx.doi.org/10.1128/MRA.00064-20

Blakeway LV; Tan A; Jurcisek JA; Bakaletz LO; Atack JM; Peak IR; Seib KL, 2019, 'The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media', BMC Microbiology, 19, http://dx.doi.org/10.1186/s12866-019-1660-y

Tan A; Li WS; Verderosa AD; Blakeway LV; D. Mubaiwa T; Totsika M; Seib KL, 2019, 'Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-39374-0

Atack JM; Murphy TF; Pettigrew MM; Seib KL; Jennings MP, 2019, 'Non-typeable Haemophilus influenzae isolates from patients with chronic obstructive pulmonary disease contain new phase-variable modA methyltransferase alleles controlling phasevarions', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-52429-6

Seib KL; Haag AF; Oriente F; Fantappiè L; Borghi S; Semchenko EA; Schulz BL; Ferlicca F; Taddei AR; Giuliani MM; Pizza M; Delany I, 2019, 'The meningococcal vaccine antigen GNA2091 is an analogue of YraP and plays key roles in outer membrane stability and virulence', FASEB Journal, 33, pp. 12324 - 12335, http://dx.doi.org/10.1096/fj.201900669R

Semchenko EA; Tan A; Borrow R; Seib KL, 2019, 'The Serogroup B Meningococcal Vaccine Bexsero Elicits Antibodies to Neisseria gonorrhoeae', Clinical Infectious Diseases, 69, pp. 1101 - 1111, http://dx.doi.org/10.1093/cid/ciy1061

Phillips ZN; Tram G; Seib KL; Atack JM, 2019, 'Phase-variable bacterial loci: How bacteria gamble to maximise fitness in changing environments', Biochemical Society Transactions, 47, pp. 1131 - 1141, http://dx.doi.org/10.1042/BST20180633

Atack JM; Murphy TF; Pettigrew MM; Seib KL; Jennings MP, 2019, 'Transcriptome sequencing data sets for determining gene expression changes mediated by phase-variable DNA methyltransferases in nontypeable haemophilus influenzae strains isolated from patients with chronic obstructive pulmonary disease', Microbiology Resource Announcements, 8, http://dx.doi.org/10.1128/MRA.00526-19

Semchenko EA; Everest-Dass AV; Jen FEC; Mubaiwa TD; Day CJ; Seib KL, 2019, 'Glycointeractome of neisseria gonorrhoeae: Identification of host glycans targeted by the gonococcus to facilitate adherence to cervical and urethral epithelial cells', Mbio, 10, http://dx.doi.org/10.1128/mBio.01339-19

Day CJ; Hartley-Tassell LE; Seib KL; Tiralongo J; Bovin N; Savino S; Masignani V; Jennings MP, 2019, 'Lectin activity of Pseudomonas aeruginosa vaccine candidates PSE17-1, PSE41-5 and PSE54', Biochemical and Biophysical Research Communications, 513, pp. 287 - 290, http://dx.doi.org/10.1016/j.bbrc.2019.03.092

Phillips ZN; Brizuela C; Jennison AV; Staples M; Grimwood K; Seib KL; Jennings MP; Atack JM, 2019, 'Analysis of invasive nontypeable Haemophilus influenzae isolates reveals selection for the expression state of particular phase-variable lipooligosaccharide biosynthetic genes', Infection and Immunity, 87, http://dx.doi.org/10.1128/IAI.00093-19

Jayasundara P; Regan DG; Seib KL; Jayasundara D; Wood JG, 2019, 'Modelling the in-host dynamics of Neisseria gonorrhoeae infection', Pathogens and Disease, 77, http://dx.doi.org/10.1093/femspd/ftz008

Hartley-Tassell LE; Awad MM; Seib KL; Scarselli M; Savino S; Tiralongo J; Lyras D; Day CJ; Jennings MP, 2019, 'Lectin activity of the TcdA and TcdB toxins of Clostridium difficile', Infection and Immunity, 87, http://dx.doi.org/10.1128/IAI.00676-18

Palmu AA; Ware RS; Lambert SB; Sarna M; Bialasiewicz S; Seib KL; Atack JM; Nissen MD; Grimwood K, 2019, 'Nasal swab bacteriology by PCR during the first 24-months of life: A prospective birth cohort study', Pediatric Pulmonology, 54, pp. 289 - 296, http://dx.doi.org/10.1002/ppul.24231

Hare KM; Seib KL; Chang AB; Harris TM; Spargo JC; Smith-Vaughan HC, 2019, 'Antimicrobial susceptibility and impact of macrolide antibiotics on moraxella catarrhalis in the upper and lower airways of children with chronic endobronchial suppuration', Journal of Medical Microbiology, 68, pp. 1140 - 1147, http://dx.doi.org/10.1099/jmm.0.001033

Brown P; Zhou Y; Tan AC; El-Esawi MA; Liehr T; Blanck O; Gladue DP; Almeida GMF; Cernava T; Sorzano CO; Yeung AWK; Engel MS; Chandrasekaran AR; Muth T; Staege MS; Daulatabad SV; Widera D; Zhang J; Meule A; Honjo K; Pourret O; Yin CC; Zhang Z; Cascella M; Flegel WA; Goodyear CS; van Raaij MJ; Bukowy-Bieryllo Z; Campana LG; Kurniawan NA; Lalaouna D; Hüttner FJ; Ammerman BA; Ehret F; Cobine PA; Tan EC; Han H; Xia W; McCrum C; Dings RPM; Marinello F; Nilsson H; Nixon B; Voskarides K; Yang L; Costa VD; Bengtsson-Palme J; Bradshaw W; Grimm DG; Kumar N; Martis E; Prieto D; Sabnis SC; Amer SEDR; Liew AWC; Perco P; Rahimi F; Riva G; Zhang C; Devkota HP; Ogami K; Basharat Z; Fierz W; Siebers R; Tan KH; Boehme KA; Brenneisen P; Brown JAL; Dalrymple BP; Harvey DJ; Ng G; Werten S; Bleackley M; Dai Z; Dhariwal R; Gelfer Y; Hartmann MD; Miotla P; Tamaian R; Govender P; Gurney-Champion OJ; Kauppila JH; Zhang X; Echeverría N; Subhash S; Sallmon H; Tofani M; Bae T; Bosch O; Cuív PO; Danchin A; Diouf B; Eerola T; Evangelou E; Filipp F; Klump H; Kurgan L; Smith SS; Terrier O; Tuttle N; Kohonen-Corish M; Lovell N; Webster R; Nakagawa-Lagisz M; Tahir N; Rouet R; Sharma S; Seib KL; Litfin T, 2019, 'Large expert-curated database for benchmarking document similarity detection in biomedical literature search', Database, 2019, pp. 1 - 67, http://dx.doi.org/10.1093/database/baz085

Phillips ZN; Husna AU; Jennings MP; Seib KL; Atack JM, 2019, 'Phasevarions of bacterial pathogens-phase-variable epigenetic regulators evolving from restriction-modification systems', Microbiology United Kingdom, 165, pp. 917 - 928, http://dx.doi.org/10.1099/mic.0.000805

Seib KL; Peak IR, 2019, 'Preface', Methods in Molecular Biology, 1969, pp. v - vii

Jen FEC; Seib KL; Tan A, 2019, 'Screening DNA repeat tracts of phase variable genes by fragment analysis', , 1969, pp. 93 - 104, http://dx.doi.org/10.1007/978-1-4939-9202-7_6

Zhan J; Jia H; Semchenko EA; Bian Y; Zhou AM; Li Z; Yang Y; Wang J; Sarkar S; Totsika M; Blanchard H; Jen FEC; Ye Q; Haselhorst T; Jennings MP; Seib KL; Zhou Y, 2019, 'Self-derived structure-disrupting peptides targeting methionine aminopeptidase in pathogenic bacteria: A new strategy to generate antimicrobial peptides', FASEB Journal, 33, pp. 2095 - 2104, http://dx.doi.org/10.1096/fj.201700613RR

Jen FEC; Semchenko EA; Day CJ; Seib KL; Jennings MP, 2019, 'The Neisseria gonorrhoeae methionine sulfoxide reductase (MsrA/B) is a surface exposed, immunogenic, vaccine candidate', Frontiers in Immunology, 10, http://dx.doi.org/10.3389/fimmu.2019.00137

Mubaiwa TD; Hartley-Tassell LE; Semchenko EA; Day CJ; Jennings MP; Seib KL, 2018, 'The Bexsero Neisseria meningitidis serogroup B vaccine antigen NHBA is a high-affinity chondroitin sulfate binding protein', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-24639-x

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