By Professor Emad El-Omar

Journal articles

Watanabe O; Ando T; El-Omar EM; Shimada M; Ina K; Ishiguro K; Hasegawa M; Miyake N; Nakamura M; Miyahara R; Ohmiya N; Niwa Y; Goto H, 2009, 'Role of endoscopic ultrasonography in predicting the response to cyclosporin A in ulcerative colitis refractory to steroids', Digestive and Liver Disease, 41, pp. 735 - 739, http://dx.doi.org/10.1016/j.dld.2009.03.014

Shanks AM; El-Omar EM, 2009, 'Helicobacter pylori infection, host genetics and gastric cancer', Journal of Digestive Diseases, 10, pp. 157 - 164, http://dx.doi.org/10.1111/j.1751-2980.2009.00380.x

McLean MH; El-Omar EM, 2009, 'Genetic aspects of inflammation', Current Opinion in Pharmacology, 9, pp. 370 - 374, http://dx.doi.org/10.1016/j.coph.2009.06.003

Epstein D; Bojke L; Sculpher MJ; Atkin W; Bancewicz J; Darzi A; Heading R; Jankowski J; Krukowski Z; Lilford R; Martin I; Mowat A; Russell I; Thursz M, 2009, 'Laparoscopic fundoplication compared with medical management for gastro-oesophageal reflux disease: Cost effectiveness study', BMJ Online, 339, pp. 152 - 155, http://dx.doi.org/10.1136/bmj.b2576

Jeffery N; McLean MH; El-Omar EM; Murray GI, 2009, 'The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers', Histopathology, 54, pp. 820 - 828, http://dx.doi.org/10.1111/j.1365-2559.2009.03301.x

Hold GL; Rabkin CS; Gammon MD; Berry SH; Smith MG; Lissowska J; Risch HA; Chow WH; Ashley G Mowat N; Vaughan TL; El-Omar EM, 2009, 'CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations', European Journal of Cancer Prevention, 18, pp. 117 - 119, http://dx.doi.org/10.1097/CEJ.0b013e3283101292

Grant AM; Wileman SM; Ramsay CR; Mowat NA; Krukowski ZH; Heading RC; Thursz MR; Campbell MK; Mowat A; El-Omar E; Phull P; Sinclair T; Swan L; Clements B; Collins J; Kennedy A; Lawther H; Bennett D; Davies N; Toop S; Winwood P; Alderson D; Barham P; Green K; Mittal R; Asante M; El Hasani S; De Beaux A; Meekison L; Paterson-Brown S; Barkell H; Ferns G; Bailey M; Karanjia N; Rockall TA; Skelly L; Dakkak M; Royston C; Sedman P; Gordon K; Potts LF; Smith C; Zentler-Munro PL; Munro A; Dexter S; Moayeddi P; Lloyd DM; Loh V; Thursz M; Darzi A; Ahmed A; Greaves R; Sawyerr A; Wellwood J; Taylor T; Hosking S; Lowrey S; Snook J; Goggin P; Johns T; Quine A; Somers S; Toh S; Bancewicz J; Greenhalgh M; Rees W; Cheruvu CVN; Deakin M; Evans S; Green J; Leslie F; Baxter JN; Duane P; Rahman MM; Thomas M; Williams J; Maxton D; Sigurdsson A; Smith MSH; Townson G; Buckley C; Gore S; Kennedy RH; Khan ZH; Knight J; Alexander D; Miller G; Parker D; Turnbull A; Turvill J, 2009, 'Minimal access surgery compared with medical management for chronic gastro-oesophageal reflux disease: UK collaborative randomised trial', BMJ Online, 338, pp. 81 - 83, http://dx.doi.org/10.1136/bmj.a2664

Mbulaiteye SM; Hisada M; El-Omar EM, 2009, 'Helicobacter Pylori associated global gastric cancer burden', Frontiers in Bioscience, 14, pp. 1490 - 1504, http://dx.doi.org/10.2741/3320

Hansen R; El-Sakka NE; Berry SH; Thomson JM; Bisset WM; Mahdi G; Murray GI; Helms PJ; Hold G; El-Omar EM, 2009, 'W1180 Are Non-Pylori Helicobacter Organisms Associated with Paediatric Ulcerative Colitis? Retrospective Observational Study', Gastroenterology, 136, pp. A - 671, http://dx.doi.org/10.1016/s0016-5085(09)63093-6

Grant AM; Wileman SM; Ramsay CR; Mowat NA; Krukowski ZH; Heading RC; Thursz MR; Campbell MK; REFLUX Trial Group , 2008, 'Minimal access surgery compared with medical management for chronic gastro-oesophageal reflux disease: UK collaborative randomised trial.', BMJ, 337, pp. a2664, http://dx.doi.org/10.1136/bmj.a2664

Mahajan R; El-Omar EM; Lissowska J; Grillo P; Rabkin CS; Baccarelli A; Yeager M; Sobin LH; Zatonski W; Channock SJ; Chow WH; Hou L, 2008, 'Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a polish population', Japanese Journal of Clinical Oncology, 38, pp. 626 - 633, http://dx.doi.org/10.1093/jjco/hyn075

Argent RH; Hale JL; El-Omar EM; Atherton JC, 2008, 'Differences in Helicobacter pylori CagA tyrosine phosphorylation motif patterns between western and East Asian strains, and influences on interleukin-8 secretion', Journal of Medical Microbiology, 57, pp. 1062 - 1067, http://dx.doi.org/10.1099/jmm.0.2008/001818-0

Grant A; Wileman S; Ramsay C; Boike L; Epstein D; Sculpher M; Macran S; Kilonzo M; Vale L; Francis J; Mowat A; Krukowski Z; Heading R; Thursz M; Russell I; Campbell M, 2008, 'The effectiveness and cost-effectiveness of minimal access surgery amongst people with gastro-oesophageal reflux disease - a UK collaborative study. The REFLUX trial', HEALTH TECHNOLOGY ASSESSMENT, 12, pp. 1 - +, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000267608400001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McNamara D; El-Omar E, 2008, 'Helicobacter pylori infection and the pathogenesis of gastric cancer: A paradigm for host-bacterial interactions', Digestive and Liver Disease, 40, pp. 504 - 509, http://dx.doi.org/10.1016/j.dld.2008.02.031

McLean MH; Murray GI; Fyfe N; Hold GL; Mowat NAG; El-Omar EM, 2008, 'COX-2 expression in sporadic colorectal adenomatous polyps is linked to adenoma characteristics', Histopathology, 52, pp. 806 - 815, http://dx.doi.org/10.1111/j.1365-2559.2008.03038.x

Snaith A; El-Omar EM, 2008, 'Helicobacter pylori: Host genetics and disease outcomes', Expert Review of Gastroenterology and Hepatology, 2, pp. 577 - 585, http://dx.doi.org/10.1586/17474124.2.4.577

Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'A single nucleotide polymorphism in the TLR9 promoter (TLR9-1237T/C) increases the affinity of NF-kappa B protein binding and enhances transcriptional activity upon H-pylori infection', GASTROENTEROLOGY, 134, pp. A567 - A567, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101504189&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'Role of chronic inflammation in sporadic colorectal neoplasia', GASTROENTEROLOGY, 134, pp. A293 - A294, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101502155&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Argent RH; Thomas RJ; Aviles-Jimenez F; Letley DP; Limb MC; El-Omar EM; Atherton JC, 2008, 'Toxigenic Helicobacter pylori infection precedes gastric hypochlorhydria in cancer relatives, and H. pylori virulence evolves in these families', Clinical Cancer Research, 14, pp. 2227 - 2235, http://dx.doi.org/10.1158/1078-0432.CCR-07-2022

Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'Variable detection of entero-hepatic Helicobacter species in colonic mucosal pinch biopsies by different molecular techniques', GASTROENTEROLOGY, 134, pp. A655 - A655, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101504599&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lochhead P; El-Omar EM, 2008, 'Gastric cancer', British Medical Bulletin, 85, pp. 87 - 100, http://dx.doi.org/10.1093/bmb/ldn007

Hold GL; El-Omar EM, 2008, 'Genetic aspects of inflammation and cancer', Biochemical Journal, 410, pp. 225 - 235, http://dx.doi.org/10.1042/BJ20071341

Amieva MR; El-Omar EM, 2008, 'Host-Bacterial Interactions in Helicobacter pylori Infection', Gastroenterology, 134, pp. 306 - 323, http://dx.doi.org/10.1053/j.gastro.2007.11.009

Rugge M; Correa P; Di Mario F; El-Omar E; Fiocca R; Geboes K; Genta RM; Graham DY; Hattori T; Malfertheiner P; Nakajima S; Sipponen P; Sung J; Weinstein W; Vieth M, 2008, 'OLGA staging for gastritis: A tutorial', Digestive and Liver Disease, 40, pp. 650 - 658, http://dx.doi.org/10.1016/j.dld.2008.02.030

El-Omar EM; Ng MT; Hold GL, 2008, 'Polymorphisms in Toll-like receptor genes and risk of cancer', Oncogene, 27, pp. 244 - 252, http://dx.doi.org/10.1038/sj.onc.1210912

McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'S1996 Role of Chronic Inflammation in Sporadic Colorectal Neoplasia', Gastroenterology, 134, http://dx.doi.org/10.1016/s0016-5085(08)61366-9

Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'T1807 A Single Nucleotide Polymorphism in the TLR9 Promoter (TLR9 −1237T/C) Increases the Affinity of NF-κB Protein Binding and Enhances Transcriptional Activity Upon H. pylori Infection', Gastroenterology, 134, pp. A - 567, http://dx.doi.org/10.1016/s0016-5085(08)62648-7

Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'W1208 Variable Detection of Entero-Hepatic Helicobacter Species in Colonic Mucosal Pinch Biopsies By Different Molecular Techniques', Gastroenterology, 134, pp. A - 655, http://dx.doi.org/10.1016/s0016-5085(08)63058-9

El-Omar EM, 2007, 'The clinician's guide to acid/peptic disorders and motility disorders of the gastrointestinal tract', Gut, 56, pp. 1487 - 1487, http://dx.doi.org/10.1136/gut.2007.121418

McNamara D; El-Omar EM, 2007, 'How accurate are fecal tests for determination of cure after Helicobacter pylori eradication therapy?: Commentary', Nature Clinical Practice Gastroenterology and Hepatology, 4, pp. 248 - 249, http://dx.doi.org/10.1038/ncpgasthep0790

Malfertheiner P; Megraud F; O'Morain CO; Bazzoli F; El-Omar E; Graham D; Hunt R; Rokkas T; Vakil N; Kuipers EJ, 2007, 'Current concepts in the management of helicobacter pylori infection - The maastricht III consensus report', Chinese Journal of Gastroenterology, 12, pp. 159

Lochhead P; El-Omar EM, 2007, 'Helicobacter pylori infection and gastric cancer', Best Practice and Research Clinical Gastroenterology, 21, pp. 281 - 297, http://dx.doi.org/10.1016/j.bpg.2007.02.002

Ando T; Goto Y; Ishiguro K; Maeda O; Watanabe O; Ohmiya N; Niwa Y; Hamajima N; El-Omar E; Goto H, 2007, 'The interaction of host genetic factors and Helicobacter pylori infection', Inflammopharmacology, 15, pp. 10 - 14, http://dx.doi.org/10.1007/s10787-006-1556-y

Hold GL; Rabkin CS; Chow WH; Smith MG; Gammon MD; Risch HA; Vaughan TL; McColl KEL; Lissowska J; Zatonski W; Schoenberg JB; Blot WJ; Mowat NAG; Fraumeni JF; El-Omar EM, 2007, 'A Functional Polymorphism of Toll-Like Receptor 4 Gene Increases Risk of Gastric Carcinoma and Its Precursors', Gastroenterology, 132, pp. 905 - 912, http://dx.doi.org/10.1053/j.gastro.2006.12.026

Malfertheiner P; Mégraud F; O’Morain C; Bazzoli F; El-Omar E; Graham DY; Hunt R; Rokkas T; Vakil N; Kuipers EJ; Andersen L; Atherton J; Asaka M; Bytzer P; Chan F; Coelho LGV; De Wit N; Delchier JC; Di Mario F; Fock KM; Forman D; Fujioka T; Gasbarrini G; Genta R; Goh KL; Hirschl A; Hungin P; Isakov VA; Jones R; Kist M; Koletzko S; Kupcinskas L; Ladas S; Lanas A; Machado J; McColl KEL; Michetti P; Moayyedi P; Pilotto A; Quina M; Sharma P; Simsek Y; Sipponen P; Sollano J; Stockbrügger R; Sugano K; Vaira D; Vieth M; Xiao S, 2007, 'Current concepts in the management of helicobacter pylori infection: The maastricht III consensus report', Gut, 56, pp. 772 - 781, http://dx.doi.org/10.1136/gut.2006.101634

Hale JL; Argent RH; El-Omar EM; Atherton JC, 2007, 'Helicobacter pylori microevolution changing CagA tyrosine phosphorylation motif-C number affects the level of IL-8 release from gastric epithelial cells', ZOONOSES AND PUBLIC HEALTH, 54, pp. 90 - 91, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000250519200306&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hou L; El-Omar EM; Chen J; Grillo P; Rabkin CS; Baccarelli A; Yeager M; Chanock SJ; Zatonski W; Sobin LH; Lissowska J; Fraumeni JF; Chow WH, 2007, 'Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer', Carcinogenesis, 28, pp. 118 - 123, http://dx.doi.org/10.1093/carcin/bgl130

, 2007, '8th Advanced Medicine Symposium : Sultan Qaboos University, Sultanate of Oman5th - 8th March 2007', Sultan Qaboos University medical journal, 7, pp. 179 - 184

Hou L; El-Omar EM; Chen J; Grillo P; Rabkin CS; Baccarelli A; Yeager M; Chanock SJ; Zatonski W; Sobin LH; Lissowska J; Fraumeni JF; Chow WH, 2007, 'Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer', CARCINOGENESIS, 28, pp. 118 - 123, http://dx.doi.org/10.1093/carcin/bgl130

Derakhshan MH; El-Omar E; Oien K; Gillen D; Fyfe V; Crabtree JE; McColl KEL, 2006, 'Gastric histology, serological markers and age as predictors of gastric acid secretion in patients infected with Helicobacter pylori', Journal of Clinical Pathology, 59, pp. 1293 - 1299, http://dx.doi.org/10.1136/jcp.2005.036111

Baccarelli A; Hou L; Chen J; Lissowska J; El-Omar EM; Grillo P; Giacomini SM; Yaeger M; Bernig T; Zatonski W; Fraumeni JF; Chanock SJ; Chow WH, 2006, 'Mannose-binding lectin-2 genetic variation and stomach cancer risk', International Journal of Cancer, 119, pp. 1970 - 1975, http://dx.doi.org/10.1002/ijc.22075

Tseng FC; Brown EE; Maiese EM; Yeager M; Welch R; Gold BD; Owens M; Cranston B; Hanchard B; El-Omar E; Hisada M, 2006, 'Polymorphisms in cytokine genes and risk of Helicobacter pylori infection among Jamaican children', Helicobacter, 11, pp. 425 - 430, http://dx.doi.org/10.1111/j.1523-5378.2006.00433.x

El-Omar EM, 2006, 'Role of host genes in sporadic gastric cancer', Best Practice and Research Clinical Gastroenterology, 20, pp. 675 - 686, http://dx.doi.org/10.1016/j.bpg.2006.04.006

Smith MG; Hold GL; Tahara E; El-Omar EM, 2006, 'Cellular and molecular aspects of gastric cancer', World Journal of Gastroenterology, 12, pp. 2979 - 2990, http://dx.doi.org/10.3748/wjg.v12.i19.2979

McLeman L; McKinlay AW; El-Omar EM, 2006, 'GP management of dyspepsia', Practitioner, 250, pp. 134 - 146

El-Omar EM, 2006, 'What is the optimal therapy for the eradication of Helicobacter pylori? Commentary', Nature Clinical Practice Gastroenterology and Hepatology, 3, pp. 126 - 127, http://dx.doi.org/10.1038/ncpgasthep0422

Ando T; El-Omar EM; Goto Y; Nobata K; Watanabe O; Maeda O; Ishiguro K; Minami M; Hamajima N; Goto H, 2006, 'Interleukin 1B proinflammatory genotypes protect against gastro-oesophageal reflux disease through induction of corpus atrophy', Gut, 55, pp. 158 - 164, http://dx.doi.org/10.1136/gut.2005.072942

El-Omar EM, 2006, 'Mechanisms of increased acid secretion after eradication of Helicobacter pylori infection', Gut, 55, pp. 144 - 146, http://dx.doi.org/10.1136/gut.2005.071779

Goto Y; Ando T; Yamamoto K; Tamakoshi A; El-Omar E; Goto H; Hamajima N, 2006, 'Association between serum pepsinogens and polymorphism of PTPN11 encoding SHP-2 among Helicobacter pylori seropositive Japanese', International Journal of Cancer, 118, pp. 203 - 208, http://dx.doi.org/10.1002/ijc.21338

Ando T; Minami M; Mizuno T; Watanabe O; Ishiguro K; Ina K; Kusugami K; Nobata K; Nishiwaki T; Tsuzuki T; Shimada M; El-Omar E; Goto H, 2005, 'Long-term follow-up after eradication of Helicobacter pylori with omeprazole, clarithromycin, and tinidazole (OCT regimen) in a Japanese population', Helicobacter, 10, pp. 379 - 384, http://dx.doi.org/10.1111/j.1523-5378.2005.00344.x

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