By Professor David Thomas

Journal articles

Thomas D; Henshaw R; Skubitz K; Chawla S; Staddon A; Blay JY; Roudier M; Smith J; Ye Z; Sohn W; Dansey R; Jun S, 2010, 'Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study', Lancet Oncology, 11, pp. 275 - 280, http://dx.doi.org/10.1016/S1470-2045(10)70010-3

Thomas D, 2010, 'MRI of Bone and Soft Tissue Sarcomas and Tumorlike Lesions', CANCER FORUM, 34, pp. 61 - 61, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000213401900018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Thomas D; Carriere P; Jacobs I, 2010, 'Safety of denosumab in giant-cell tumour of bone', Lancet Oncology, 11, pp. 815, http://dx.doi.org/10.1016/S1470-2045(10)70170-4

Thomas DM; Wagner AJ, 2010, 'Specific targets in sarcoma and developmental therapeutics', Jnccn Journal of the National Comprehensive Cancer Network, 8, pp. 677 - 685, http://dx.doi.org/10.6004/jnccn.2010.0050

Thomas DM, 2010, 'Wnts, bone and cancer', Journal of Pathology, 220, pp. 1 - 4, http://dx.doi.org/10.1002/path.2635

Conyers R; Thomas D, 2010, 'Review of “Cancer – basic science and clinical aspects”', BioEssays, 32, pp. 914 - 916, http://dx.doi.org/10.1002/bies.201000084

Angoa-Pérez M; Kreipke CW; Thomas DM; Van Shura KE; Lyman M; McDonough JH; Kuhn DM, 2010, 'Soman increases neuronal COX-2 levels: possible link between seizures and protracted neuronal damage.', Neurotoxicology, 31, pp. 738 - 746, http://dx.doi.org/10.1016/j.neuro.2010.06.007

Thomas DM, 2010, 'The importance of molecular and anatomic pathology in cancer management', Pathology, 42, pp. S31 - S31, http://dx.doi.org/10.1097/01268031-201042001-00063

Thomas DM, 2010, 'The importance of molecular and anatomic pathology in cancer management', Pathology, 42, pp. S12 - S12, http://dx.doi.org/10.1097/01268031-201042001-00014

Thomas DM; Angoa Pérez M; Francescutti-Verbeem DM; Shah MM; Kuhn DM, 2010, 'The role of endogenous serotonin in methamphetamine-induced neurotoxicity to dopamine nerve endings of the striatum.', J Neurochem, 115, pp. 595 - 605, http://dx.doi.org/10.1111/j.1471-4159.2010.06950.x

Garsed DW; Holloway AJ; Thomas DM, 2009, 'Cancer-associated neochromosomes: A novel mechanism of oncogenesis', Bioessays, 31, pp. 1191 - 1200, http://dx.doi.org/10.1002/bies.200800208

Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ (Cancer Research (2009) 69, (7473-7479))', Cancer Research, 69, pp. 8832, http://dx.doi.org/10.1158/0008-5472.CAN-09-3870

Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ', Cancer Research, 69, pp. 7473 - 7479, http://dx.doi.org/10.1158/0008-5472.CAN-09-0194

Wood MA; Thomas DM; Simpson JC, 2009, 'SPH simulations of negative (nodal) superhumps: a parametric study', Monthly Notices of the Royal Astronomical Society, 398, pp. 2110 - 2121, http://dx.doi.org/10.1111/j.1365-2966.2009.15252.x

Thomas DM; O'Sullivan B; Gronchi A, 2009, 'Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management', Expert Review of Anticancer Therapy, 9, pp. 1145 - 1157, http://dx.doi.org/10.1586/ERA.09.77

Khamly KK; Thursfield VJ; Fay M; Desai J; Toner GC; Choong PFM; Ngan SYK; Powell GJ; Thomas DM, 2009, 'Gender-specific activity of chemotherapy correlates with outcomes in chemosensitive cancers of young adulthood', International Journal of Cancer, 125, pp. 426 - 431, http://dx.doi.org/10.1002/ijc.24376

Thomas DM; Skubitz KM, 2009, 'Giant cell tumour of bone', Current Opinion in Oncology, 21, pp. 338 - 344, http://dx.doi.org/10.1097/CCO.0b013e32832c951d

Soliman H; Ferrari A; Thomas D, 2009, 'Sarcoma in the Young Adult Population: An International View', Seminars in Oncology, 36, pp. 227 - 236, http://dx.doi.org/10.1053/j.seminoncol.2009.03.006

Thomas DM; Chawla S; Skubitz K; Staddon A; Henshaw R; Blay J; Smith J; Ye Z; Roudier M; Jun S, 2009, 'Denosumab for the treatment of giant cell tumor (GCT) of bone: Final results from a proof-of-concept, phase II study', Journal of Clinical Oncology, 27, pp. 10510 - 10510, http://dx.doi.org/10.1200/jco.2009.27.15_suppl.10510

Kansara M; Tsang M; Kodjabachian L; Sims NA; Trivett MK; Ehrich M; Dobrovic A; Slavin J; Choong PFM; Simmons PJ; Dawid IB; Thomas DM, 2009, 'Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice', Journal of Clinical Investigation, 119, pp. 837 - 851, http://dx.doi.org/10.1172/JCI37175

Thomas D; Whyte S; Choong P, 2009, 'Australian Sarcona Study Group: Development and outlook', Cancer Forum, 33, pp. 25 - 28

Pires de Camargo V; van de Rijn M; de Alava E; Madoz-Gúrpide J; Pilotti S; von Mehren M; Pedeutour F; Maki RG; Rutkowski P; Thomas DM, 2009, 'Other Targetable Sarcomas', Seminars in Oncology, 36, pp. 358 - 371, http://dx.doi.org/10.1053/j.seminoncol.2009.06.008

Thomas DM; Francescutti-Verbeem DM; Kuhn DM, 2009, 'Increases in cytoplasmic dopamine compromise the normal resistance of the nucleus accumbens to methamphetamine neurotoxicity.', J Neurochem, 109, pp. 1745 - 1755, http://dx.doi.org/10.1111/j.1471-4159.2009.06094.x

Newnham GM; Thomas DM; McLachlan SA; Wright G; Conron M, 2008, 'Molecular Profiling of Non-Small Cell Lung Cancer: Of What Value in Clinical Practice?', Heart Lung and Circulation, 17, pp. 451 - 462, http://dx.doi.org/10.1016/j.hlc.2007.11.144

Gutierrez GM; Kong E; Sabbagh Y; Brown NE; Lee JS; Demay MB; Thomas DM; Hinds PW, 2008, 'Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice', Proceedings of the National Academy of Sciences of the United States of America, 105, pp. 18402 - 18407, http://dx.doi.org/10.1073/pnas.0805925105

Alvaro F; Young A; Goldstein D; Thomas D; McJannett M; Dillon R, 2008, 'Clinical oncological society of Australia: Adolescent and young adult cancer forum', Cancer Forum, 32, pp. 116 - 119

Thomas D; Chawla SP; Skubitz K; Staddon AP; Henshaw R; Blay JY; Smith J; Ye Z; Roudier M; Jun S, 2008, 'Denosumab treatment of giant cell tumor of bone: Interim analysis of an open-label phase II study', Journal of Clinical Oncology, 26, pp. 10500 - 10500, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.10500

Thomas DM; Francescutti-Verbeem DM; Kuhn DM, 2008, 'The newly synthesized pool of dopamine determines the severity of methamphetamine-induced neurotoxicity', JOURNAL OF NEUROCHEMISTRY, 105, pp. 605 - 616, http://dx.doi.org/10.1111/j.1471-4159.2007.05155.x

Bleyer A; Barr R; Hayes-Lattin B; Thomas D; Ellis C; Anderson B, 2008, 'The distinctive biology of cancer in adolescents and young adults', Nature Reviews Cancer, 8, pp. 288 - 298, http://dx.doi.org/10.1038/nrc2349

Khamly KK; Hicks RJ; McArthur GA; Thomas DM, 2008, 'The promise of PET in clinical management and as a sensitive test for drug cytotoxicity in sarcomas', Expert Review of Molecular Diagnostics, 8, pp. 105 - 119, http://dx.doi.org/10.1586/14737159.8.1.105

Kuhn DM; Francescutti-Verbeem DM; Thomas DM, 2008, 'Dopamine disposition in the presynaptic process regulates the severity of methamphetamine-induced neurotoxicity.', Ann N Y Acad Sci, 1139, pp. 118 - 126, http://dx.doi.org/10.1196/annals.1432.026

Thomas DM; Francescutti-Verbeem DM; Kuhn DM, 2008, 'Methamphetamine-induced neurotoxicity and microglial activation are not mediated by fractalkine receptor signaling.', J Neurochem, 106, pp. 696 - 705, http://dx.doi.org/10.1111/j.1471-4159.2008.05421.x

Clark JCM; Thomas DM; Choong PFM; Dass CR, 2007, 'RECK - A newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer', Cancer and Metastasis Reviews, 26, pp. 675 - 683, http://dx.doi.org/10.1007/s10555-007-9093-8

Fon A; Mileshkin L; Slavin J; Twomey H; James P; Thomas DM, 2007, 'Synchronous diagnosis of Hodgkin lymphoma and osteosarcoma [1]', Internal Medicine Journal, 37, pp. 731 - 732, http://dx.doi.org/10.1111/j.1445-5994.2007.01465.x

Thomas DM, 2007, 'Adolescents and young adults with cancer: The challenge', Palliative and Supportive Care, 5, pp. 173 - 174, http://dx.doi.org/10.1017/S1478951507070253

Kansara M; Thomas DM, 2007, 'Molecular pathogenesis of osteosarcoma', DNA and Cell Biology, 26, pp. 1 - 18, http://dx.doi.org/10.1089/dna.2006.0505

Krypuy M; Newnham GM; Thomas DM; Conron M; Dobrovic A, 2006, 'High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer', BMC Cancer, 6, http://dx.doi.org/10.1186/1471-2407-6-295

Chaffer CL; Thomas DM; Thompson EW; Williams ED, 2006, 'PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma', BMC Cancer, 6, http://dx.doi.org/10.1186/1471-2407-6-53

Tan JZY; Schlicht SM; Powell GJ; Thomas D; Slavin JL; Smith PJ; Choong PFM, 2006, 'Multidisciplinary approach to diagnosis and management of osteosarcoma - A review of the St Vincent's Hospital experience', International Seminars in Surgical Oncology, 3, http://dx.doi.org/10.1186/1477-7800-3-38

Wernli KJ; Astrakianakis G; Camp JE; Ray RM; Chang CK; Li GD; Thomas DB; Checkoway H; Seixas NS, 2006, 'Development of a job exposure matrix (JEM) for the textile industry in Shanghai, China', Journal of Occupational and Environmental Hygiene, 3, pp. 521 - 529, http://dx.doi.org/10.1080/15459620600902166

Thomas D; Kansara M, 2006, 'Epigenetic modifications in osteogenic differentiation and transformation', Journal of Cellular Biochemistry, 98, pp. 757 - 769, http://dx.doi.org/10.1002/jcb.20850

Vamre TBA; Stalsberg H; Thomas DB; Berry G; Maclennan R; Shearman R; Jelihovsky T; Booth JC; Molina R; Martinez L; Salas O; Dabacens A; Zhiheng C; Yun T; Wei HY; Cuadros A; Aristizabal N; Ebeling K; Nishan P; Kunde D; Modan B; Ron E; Alfandary E; Mati JG; Kenya P; Kungu A; Gatei D; Cuevas HR; Salazar SB; Palet A; Ontiveros P; Apelo RA; De La Cruz JR; Baens J; Javier B; Silpisornkosol S; Pardthaisong T; Martin N; Theetranont C; Boosiri B; Chutivongse S; Virutamasen P; Wongsrichanalai C; Jimakorn P; Koetsawang S; Rachawat D; Chantarakul N; Ray RM; Noonan EA; Holck S, 2006, 'Extra-tumoral breast tissue in breast cancer patients: Variations with steroid contraceptive use', International Journal of Cancer, 118, pp. 2827 - 2831, http://dx.doi.org/10.1002/ijc.21697

Lee JS; Thomas DM; Gutierrez G; Carty SA; Yanagawa SI; Hinds PW, 2006, 'HES1 cooperates with pRb to activate RUNX2-dependent transcription', Journal of Bone and Mineral Research, 21, pp. 921 - 933, http://dx.doi.org/10.1359/jbmr.060303

Thomas DM; Seymour JF; O'Brien T; Sawyer SM; Ashley DM, 2006, 'Adolescent and young adult cancer: A revolution in evolution?', Internal Medicine Journal, 36, pp. 302 - 307, http://dx.doi.org/10.1111/j.1445-5994.2006.01062.x

Amukotuwa SA; Choong PFM; Smith PJ; Powell GJ; Thomas D; Schlicht SM, 2006, 'Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma', Skeletal Radiology, 35, pp. 311 - 318, http://dx.doi.org/10.1007/s00256-005-0044-6

Sakowski SA; Geddes TJ; Thomas DM; Levi E; Hatfield JS; Kuhn DM, 2006, 'Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies.', Brain Res, 1085, pp. 11 - 18, http://dx.doi.org/10.1016/j.brainres.2006.02.047

Slavin JL; Thomas D, 2006, 'Gene expression profiling of sarcomas', Pathology, 38, pp. 101 - 102, http://dx.doi.org/10.1080/00313020600595854

Gold LS; De Roos AJ; Ray RM; Wernli K; Fitzgibbons ED; Gao D-L; Astrakianakis G; Feng Z; Thomas D; Checkoway H, 2006, 'Brain tumors and occupational exposures in a cohort of female textile workers in Shanghai, China.', Scand J Work Environ Health, 32, pp. 178 - 184, http://dx.doi.org/10.5271/sjweh.996

Thomas DM; Francescutti-Verbeem DM; Kuhn DM, 2006, 'Gene expression profile of activated microglia under conditions associated with dopamine neuronal damage.', FASEB J, 20, pp. 515 - 517, http://dx.doi.org/10.1096/fj.05-4873fje

Cullinane C; Dorow DS; Kansara M; Conus N; Binns D; Hicks RJ; Ashman LK; McArthur GA; Thomas DM, 2005, 'An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development', Cancer Research, 65, pp. 9633 - 9636, http://dx.doi.org/10.1158/0008-5472.CAN-05-2285

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