By Professor Cynthia Shannon Weickert

Journal articles

Law A; Kleinman JE; Weinberger DR; Shannon-Weickert C, 2007, 'Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia', Human Molecular Genetics, 16, pp. 129 - 141

Shannon-Weickert C; Webster MA; Gondipalli P; Rothmond D; Fatula RJ; Herman M; Kleinman JE; Akil M, 2007, 'Postnatal alterations in dopaminergic markers in the human prefrontal cortex', Neuroscience, 144, pp. 1109 - 1119

Thompson M; Lauderdale S; Webster MA; Chong VZ; McClintock B; Saunders R; Shannon-Weickert C, 2007, 'Widespread expression of ErbB2, ErbB3 and ErbB4 in non-human primate brain', Brain Research, 1139, pp. 95 - 109

Eastwood SL; Weickert CS; Webster MJ; Herman MM; Kleinman JE; Harrison PJ, 2006, 'Synaptophysin protein and mRNA expression in the human hippocampal formation from birth to old age', Hippocampus, 16, pp. 645 - 654, http://dx.doi.org/10.1002/hipo.20194

Webster MJ; Herman MM; Kleinman JE; Shannon Weickert C, 2006, 'BDNF and trkB mRNA expression in the hippocampus and temporal cortex during the human lifespan', Gene Expression Patterns, 6, pp. 941 - 951, http://dx.doi.org/10.1016/j.modgep.2006.03.009

Lipska BK; Deep-Soboslay A; Weickert CS; Hyde TM; Martin CE; Herman MM; Kleinman JE, 2006, 'Critical Factors in Gene Expression in Postmortem Human Brain: Focus on Studies in Schizophrenia', Biological Psychiatry, 60, pp. 650 - 658, http://dx.doi.org/10.1016/j.biopsych.2006.06.019

Law AJ; Lipska BK; Weickert CS; Hyde TM; Straub RE; Hashimoto R; Harrison PJ; Kleinman JE; Weinberger DR, 2006, 'Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease', Proceedings of the National Academy of Sciences of the United States of America, 103, pp. 6747 - 6752, http://dx.doi.org/10.1073/pnas.0602002103

Lipska BK; Peters T; Hyde TM; Halim N; Horowitz C; Mitkus S; Weickert CS; Matsumoto M; Sawa A; Straub RE; Vakkalanka R; Herman MM; Weinberger DR; Kleinman JE, 2006, 'Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs', Human Molecular Genetics, 15, pp. 1245 - 1258, http://dx.doi.org/10.1093/hmg/ddl040

Law AJ; Lipska BK; Weickert CS; Hyde TM; Straub RE; Hashimoto R; Harrison PJ; Kleinman JE; Weinberger DR, 2006, 'Neuregulin 1 Transcripts Are Differentially Expressed in Schizophrenia and Regulated by 5′ SNPs Associated With the Disease', Focus, 4, pp. 350 - 359, http://dx.doi.org/10.1176/foc.4.3.350

Perlman WR; Tomaskovic-Crook E; Montague DM; Webster MJ; Rubinow DR; Kleinman JE; Weickert CS, 2005, 'Alteration in estrogen receptor α mRNA levels in frontal cortex and hippocampus of patients with major mental illness', Biological Psychiatry, 58, pp. 812 - 824, http://dx.doi.org/10.1016/j.biopsych.2005.04.047

Matsumoto M; Beltaifa S; Weickert CS; Herman MM; Hyde TM; Saunders RC; Lipska BK; Weinberger DR; Kleinman JE, 2005, 'A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain', Molecular Brain Research, 138, pp. 58 - 69, http://dx.doi.org/10.1016/j.molbrainres.2005.04.002

Perlman WR; Matsumoto M; Beltaifa S; Hyde TM; Saunders RC; Webster MJ; Rubinow DR; Kleinman JE; Weickert CS, 2005, 'Expression of estrogen receptor alpha exon-deleted mRNA variants in the human and non-human primate frontal cortex', Neuroscience, 134, pp. 81 - 95, http://dx.doi.org/10.1016/j.neuroscience.2005.03.055

Weickert CS; Ligons DL; Romanczyk T; Ungaro G; Hyde TM; Herman MM; Weinberger DR; Kleinman JE, 2005, 'Reductions in neurotrophin receptor mRNAs in the prefrontal cortex of patients with schizophrenia', Molecular Psychiatry, 10, pp. 637 - 650, http://dx.doi.org/10.1038/sj.mp.4001678

Webster MJ; O'Grady J; Kleinman JE; Weickert CS, 2005, 'Glial fibrillary acidic protein mRNA levels in the cingulate cortex of individuals with depression, bipolar disorder and schizophrenia', Neuroscience, 133, pp. 453 - 461, http://dx.doi.org/10.1016/j.neuroscience.2005.02.037

Beltaifa S; Webster MJ; Ligons DL; Fatula RJ; Herman MM; Kleinman JE; Weickert CS, 2005, 'Discordant changes in cortical TrkC mRNA and protein during the human lifespan', European Journal of Neuroscience, 21, pp. 2433 - 2444, http://dx.doi.org/10.1111/j.1460-9568.2005.04074.x

Weickert CS; Kittell DA; Saunders RC; Herman MM; Horlick RA; Kleinman JE; Hyde TM, 2005, 'Basic fibroblast growth factor and fibroblast growth factor receptor-1 in the human hippocampal formation', Neuroscience, 131, pp. 219 - 233, http://dx.doi.org/10.1016/j.neuroscience.2004.09.070

Perlman WR; Webster MJ; Kleinman JE; Weickert CS, 2004, 'Reduced glucocorticoid and estrogen receptor alpha messenger ribonucleic acid levels in the amygdala of patients with major mental illness', Biological Psychiatry, 56, pp. 844 - 852, http://dx.doi.org/10.1016/j.biopsych.2004.09.006

Egan MF; Straub RE; Goldberg TE; Yakub I; Callicott JH; Hariri AR; Mattay VS; Bertolino A; Hyde TM; Shannon-Weickert C; Akil M; Crook J; Vakkalanka RK; Balkissoon R; Gibbs RA; Kleinman JE; Weinberger DR, 2004, 'Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia', Proceedings of the National Academy of Sciences of the United States of America, 101, pp. 12604 - 12609, http://dx.doi.org/10.1073/pnas.0405077101

Law AJ; Shannon Weickert C; Hyde TM; Kleinman JE; Harrison PJ, 2004, 'Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain', Neuroscience, 127, pp. 125 - 136, http://dx.doi.org/10.1016/j.neuroscience.2004.04.026

Perlman WR; Weickert CS; Akil M; Kleinman JE, 2004, 'Postmortem investigations of the pathophysiology of schizophrenia: The role of susceptibility genes', Journal of Psychiatry and Neuroscience, 29, pp. 287 - 293

Halim ND; Weickert CS; McClintock BW; Weinberger DR; Lipska BK, 2004, 'Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus', Neuropsychopharmacology, 29, pp. 1063 - 1069, http://dx.doi.org/10.1038/sj.npp.1300422

Vawter MP; Weickert CS; Ferran E; Matsumoto M; Overman K; Hyde TM; Weinberger DR; Bunney WE; Kleinman JE, 2004, 'Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophrenia', Neurochemical Research, 29, pp. 1245 - 1255, http://dx.doi.org/10.1023/B:NERE.0000023611.99452.47

Weickert CS; Straub RE; McClintock BW; Matsumoto M; Hashimoto R; Hyde TM; Herman MM; Weinberger DR; Kleinman JE, 2004, 'Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain', Archives of General Psychiatry, 61, pp. 544 - 555, http://dx.doi.org/10.1001/archpsyc.61.6.544

Wang J; Cheng CM; Zhou J; Smith A; Weickert CS; Perlman WR; Becker KG; Powell D; Bondy CA, 2004, 'Estradiol Alters Transcription Factor Gene Expression in Primate Prefrontal Cortex', Journal of Neuroscience Research, 76, pp. 306 - 314, http://dx.doi.org/10.1002/jnr.20076

Hashimoto R; Straub RE; Weickert CS; Hyde TM; Kleinman JE; Weinberger DR, 2004, 'Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia', Molecular Psychiatry, 9, pp. 299 - 307, http://dx.doi.org/10.1038/sj.mp.4001434

Smith A; Wang J; Cheng CM; Zhou J; Weickert CS; Bondy CA, 2004, 'High-Level Expression of Dok-1 in Neurons of the Primate Prefrontal Cortex and Hippocampus', Journal of Neuroscience Research, 75, pp. 218 - 224, http://dx.doi.org/10.1002/jnr.10842

Ghose S; Weickert CS; Colvin SM; Coyle JT; Herman MM; Hyde TM; Kleinman JE, 2004, 'Glutamate Carboxypeptidase II Gene Expression in the Human Frontal and Temporal Lobe in Schizophrenia', Neuropsychopharmacology, 29, pp. 117 - 125, http://dx.doi.org/10.1038/sj.npp.1300304

Law AJ; Weickert CS; Hyde TM; Kleinman JE; Harrison PJ, 2004, 'Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: Molecular evidence for a pathology of dendritic spines', American Journal of Psychiatry, 161, pp. 1848 - 1855, http://dx.doi.org/10.1176/ajp.161.10.1848

Perlman WR; Weickert CS; Akil M; Kleinman JE, 2004, 'Postmortem investigations of the pathophysiology of schizophrenia: the role of susceptibility genes', Journal of Psychiatry and Neuroscience, 29, pp. 287 - 293, http://dx.doi.org/10.1139/jpn.0430

Shanon-Weickert C; Kozlovsky N; Tomaskovic-Crook E; Kleinman JE; Belmaker RH; Agam G; Shannon Weickert C, 2004, 'Reduced GSK-alpha mRNA levels in postmortem dorsolateral prefrontal cortex of schizophrenic patients.', Journal of Neural Transmission, 111, pp. 1583 - 1592, http://dx.doi.org/10.1007/s00702-004-0166-3

Halim ND; Weickert CS; McClintock BW; Hyde TM; Weinberger DR; Kleinman JE; Lipska BK, 2003, 'Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development', Molecular Psychiatry, 8, pp. 797 - 810, http://dx.doi.org/10.1038/sj.mp.4001319

Law AJ; Weickert CS; Webster MJ; Herman MM; Kleinman JE; Harrison PJ, 2003, 'Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation', European Journal of Neuroscience, 18, pp. 1197 - 1205, http://dx.doi.org/10.1046/j.1460-9568.2003.02850.x

Weickert CS; Hyde TM; Lipska BK; Herman MM; Weinberger DR; Kleinman JE, 2003, 'Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia', Molecular Psychiatry, 8, pp. 592 - 610, http://dx.doi.org/10.1038/sj.mp.4001308

Matsumoto M; Weickert CS; Beltaifa S; Kolachana B; Chen J; Hyde TM; Herman MM; Weinberger DR; Kleinman JE, 2003, 'Catechol O-methyltransferase (COMT) mRNA expression in the dorsolateral prefrontal cortex of patients with schizophrenia', Neuropsychopharmacology, 28, pp. 1521 - 1530, http://dx.doi.org/10.1038/sj.npp.1300218

Matsumoto M; Weickert CS; Akil M; Lipska BK; Hyde TM; Herman MM; Kleinman JE; Weinberger DR, 2003, 'Catechol O-methyltransferase mRNA expression in human and rat brain: Evidence for a role in cortical neuronal function', Neuroscience, 116, pp. 127 - 137, http://dx.doi.org/10.1016/S0306-4522(02)00556-0

Carrasco E; Blum M; Weickert CS; Casper D, 2003, 'Epidermal growth factor receptor expression is related to post-mitotic events in cerebellar development: Regulation by thyroid hormone', Developmental Brain Research, 140, pp. 1 - 13, http://dx.doi.org/10.1016/S0165-3806(02)00539-4

Law AJ; Weickert CS; Webster MJ; Herman MM; Kleinman JE; Harrison PJ, 2003, 'Changes in NMDA Receptor Subunit mRNAs and Cyclophilin mRNA during Development of the Human Hippocampus', Annals of the New York Academy of Sciences, 1003, pp. 426 - 430, http://dx.doi.org/10.1196/annals.1300.043

Lipska BK; Lerman DN; Khaing ZZ; Weickert CS; Weinberger DR, 2003, 'Gene expression in dopamine and GABA systems in an animal model of schizophrenia: Effects of antipsychotic drugs', European Journal of Neuroscience, 18, pp. 391 - 402, http://dx.doi.org/10.1046/j.1460-9568.2003.02738.x

Romanczyk TB; Weickert CS; Webster MJ; Herman MM; Akil M; Kleinman JE, 2002, 'Alterations in trkB mRNA in the human prefrontal cortex throughout the lifespan', European Journal of Neuroscience, 15, pp. 269 - 280, http://dx.doi.org/10.1046/j.0953-816x.2001.01858.x

Webster MJ; Weickert CS; Herman MM; Kleinman JE, 2002, 'BDNF mRNA expression during postnatal development, maturation and aging of the human prefrontal cortex', Developmental Brain Research, 139, pp. 139 - 150, http://dx.doi.org/10.1016/S0165-3806(02)00540-0

Webster MJ; Knable MB; O'Grady J; Orthmann J; Weickert CS, 2002, 'Regional specificity of brain glucocorticoid receptor mRNA alterations in subjects with schizophrenia and mood disorders', Molecular Psychiatry, 7, pp. 985 - 994, http://dx.doi.org/10.1038/sj.mp.4001139

Webster MJ; Shannon Weickert C; Herman MM; Hyde TM; Kleinman JE, 2001, 'Synaptophysin and GAP-43 mRNA levels in the hippocampus of subjects with schizophrenia', Schizophrenia Research, 49, pp. 89 - 98, http://dx.doi.org/10.1016/S0920-9964(00)00052-9

Al-Amin HA; Shannon Weickert C; Weinberger DR; Lipska BK, 2001, 'Delayed onset of enhanced MK-801-induced motor hyperactivity after neonatal lesions of the rat ventral hippocampus', Biological Psychiatry, 49, pp. 528 - 539, http://dx.doi.org/10.1016/S0006-3223(00)00968-9

Lipska BK; Khaing ZZ; Weickert CS; Weinberger DR, 2001, 'BDNF mRNA expression in rat hippocampus and prefrontal cortex: Effects of neonatal ventral hippocampal damage and antipsychotic drugs', European Journal of Neuroscience, 14, pp. 135 - 144, http://dx.doi.org/10.1046/j.1460-9568.2001.01633.x

Weickert CS; Webster MJ; Hyde TM; Herman MM; Bachus SE; Bali G; Weinberger DR; Kleinman JE, 2001, 'Reduced GAP-43 mRNA in dorsolateral prefrontal cortex of patients with schizophrenia', Cerebral Cortex, 11, pp. 136 - 147, http://dx.doi.org/10.1093/cercor/11.2.136

Khaing ZZ; Weickert CS; Weinberger DR; Lipska BK, 2000, 'Differential DNA damage in response to the neonatal and adult excitotoxic hippocampal lesion in rats', European Journal of Neuroscience, 12, pp. 4424 - 4433, http://dx.doi.org/10.1046/j.0953-816X.2000.01320.x

Weickert CS; Webster MJ; Colvin SM; Herman MM; Hyde TM; Weinberger DR; Kleinman JE, 2000, 'Localization of epidermal growth factor receptors and putative neuoblasts in human subependymal zone', Journal of Comparative Neurology, 423, pp. 359 - 372, http://dx.doi.org/10.1002/1096-9861(20000731)423:3<359::AID-CNE1>3.0.CO;2-0

Blum M; Weickert C; Carrasco E, 1999, 'The weaver GIRK2 mutation leads to decreased levels of serum thyroid hormone: Characterization of the effect on midbrain dopaminergic neuron survival', Experimental Neurology, 160, pp. 413 - 424, http://dx.doi.org/10.1006/exnr.1999.7231

Weickert CS; Weinberger DR, 1998, 'A candidate molecule approach to defining developmental pathology in schizophrenia', Schizophrenia Bulletin, 24, pp. 303 - 316, http://dx.doi.org/10.1093/oxfordjournals.schbul.a033327

Weickert CS; Kleinman JE, 1998, 'The neuroanatomy and neurochemistry of schizophrenia', Psychiatric Clinics of North America, 21, pp. 57 - 75, http://dx.doi.org/10.1016/S0193-953X(05)70361-0

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