By Professor Christopher Carl Goodnow

Journal articles

De Sousa SMC; Haghighi KS; Qiu MR; Greenfield JR; Chen DLT, 2016, 'Synchronous Nesidioblastosis, Endocrine Microadenoma, and Intraductal Papillary Mucinous Neoplasia in a Man Presenting with Hyperinsulinemic Hypoglycemia', Pancreas, 45, pp. 154 - 159, http://dx.doi.org/10.1097/MPA.0000000000000430

Ellyard JI; Jerjen R; Martin JL; Lee A; Field MA; Jiang SH; Cappello J; Naumann SK; Andrews TD; Scott HS; Casarotto MG; Goodnow CC; Chaitow J; Pascual V; Hertzog P; Alexander SI; Cook MC; Vinuesa CG, 2016, 'Identification of a pathogenic variant in TREX1 in early-onset cerebral SLE by whole-exome sequencing', Pathology, 48, pp. S47 - S47, http://dx.doi.org/10.1016/j.pathol.2015.12.120

Wertz IE; Newton K; Seshasayee D; Kusam S; Lam C; Zhang J; Popovych N; Helgason E; Schoeffler A; Jeet S; Ramamoorthi N; Kategaya L; Newman RJ; Horikawa K; Dugger D; Sandoval W; Mukund S; Zindal A; Martin F; Quan C; Tom J; Fairbrother WJ; Townsend M; Warming S; Devoss J; Liu J; Dueber E; Caplazi P; Lee WP; Goodnow CC; Balazs M; Yu K; Kolumam G; Dixit VM, 2015, 'Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation', Nature, 528, pp. 370 - 375, http://dx.doi.org/10.1038/nature16165

Lee P; Greenfield JR, 2015, 'Non-pharmacological and pharmacological strategies of brown adipose tissue recruitment in humans', Molecular and Cellular Endocrinology, 418, pp. 184 - 190, http://dx.doi.org/10.1016/j.mce.2015.05.025

Chaudhuri R; Khoo PS; Tonks K; Junutula JR; Kolumam G; Modrusan Z; Samocha-Bonet D; Meoli CC; Hocking S; Fazakerley DJ; Stöckli J; Hoehn KL; Greenfield JR; Yang JYH; James DE; Milliken S; Goodnow C, 2015, 'Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity', Npj Systems Biology and Applications, 1, pp. 15010, http://dx.doi.org/10.1038/npjsba.2015.10

Chen DL; Liess C; Poljak A; Xu A; Zhang J; Thoma C; Trenell M; Milner B; Jenkins AB; Chisholm DJ; Samocha-Bonet D; Greenfield JR, 2015, 'Phenotypic characterization of insulin-resistant and insulin-sensitive obesity', Journal of Clinical Endocrinology and Metabolism, 100, pp. 4082 - 4091, http://dx.doi.org/10.1210/jc.2015-2712

Field MA; Cho V; Andrews TD; Goodnow CC, 2015, 'Reliably detecting clinically important variants requires both combined variant calls and optimized filtering strategies', Plos One, 10, http://dx.doi.org/10.1371/journal.pone.0143199

Kayagaki N; Stowe IB; Lee BL; O'Rourke K; Anderson K; Warming S; Cuellar T; Haley B; Roose-Girma M; Phung QT; Liu PS; Lill JR; Li H; Wu J; Kummerfeld S; Zhang J; Lee WP; Snipas SJ; Salvesen GS; Morris LX; Fitzgerald L; Zhang Y; Bertram EM; Goodnow CC; Dixit VM, 2015, 'Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling', Nature, 526, pp. 666 - 671, http://dx.doi.org/10.1038/nature15541

Ramiscal RR; Parish IA; Lee-Young RS; Babon JJ; Blagih J; Pratama A; Martin J; Hawley N; Cappello JY; Nieto PF; Ellyard JI; Kershaw NJ; Sweet RA; Goodnow CC; Jones RG; Febbraio MA; Vinuesa CG; Athanasopoulos V, 2015, 'Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation', Elife, 4, pp. 1 - 22, http://dx.doi.org/10.7554/eLife.08698

Greenfield JRF; Kuhn S; Mehler D; Puel F; Rommens PM, 2015, 'Biomechanical evaluation of a new treatment method for distal tibia fractures', COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 18, pp. 1952 - 1953, http://dx.doi.org/10.1080/10255842.2015.1069582

Fuchs S; Rensing-Ehl A; Pannicke U; Lorenz MR; Fisch P; Jeelall Y; Rohr J; Speckmann C; Vraetz T; Farmand S; Schmitt-Graeff A; Krüger M; Strahm B; Henneke P; Enders A; Horikawa K; Goodnow C; Schwarz K; Ehl S, 2015, 'Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency', Blood, 126, pp. 1658 - 1669, http://dx.doi.org/10.1182/blood-2015-03-631374

Miosge LA; Field MA; Sontani Y; Cho V; Johnson S; Palkova A; Balakishnan B; Liang R; Zhang Y; Lyon S; Beutler B; Whittle B; Bertram EM; Enders A; Goodnow CC; Andrewsa TD, 2015, 'Comparison of predicted and actual consequences of missense mutations', Proceedings of the National Academy of Sciences of the United States of America, 112, pp. E5189 - E5198, http://dx.doi.org/10.1073/pnas.1511585112

Tangye SG; Brink R; Goodnow CC; Phan TG, 2015, 'SnapShot: Interactions between B Cells and T Cells', Cell, 162, pp. 926 - 926.e1, http://dx.doi.org/10.1016/j.cell.2015.07.055

Williams RS; Heilbronn LK; Chen DL; Coster A; Greenfield JR; Samocha-Bonet D; Milliken S; Goodnow C; Chen D, 2015, 'Dietary acid load, metabolic acidosis and insulin resistance - Lessons from cross-sectional and overfeeding studies in humans', Clinical Nutrition, 35, pp. 1084 - 1090, http://dx.doi.org/10.1016/j.clnu.2015.08.002

Field MA; Cho V; Cook MC; Enders A; Vinuesa CG; Whittle B; Andrews TD; Goodnow CC, 2015, 'Reducing the search space for causal genetic variants with VASP', Bioinformatics, 31, pp. 2377 - 2379, http://dx.doi.org/10.1093/bioinformatics/btv135

Flesch IEA; Randall KL; Hollett NA; Di Law H; Miosge LA; Sontani Y; Goodnow CC; Tscharke DC, 2015, 'Delayed control of herpes simplex virus infection and impaired CD4+ T-cell migration to the skin in mouse models of DOCK8 deficiency', Immunology and Cell Biology, 93, pp. 517 - 521, http://dx.doi.org/10.1038/icb.2015.32

Rahimpour A; Koay HF; Enders A; Clanchy R; Eckle SBG; Meehan B; Chen Z; Whittle B; Liu L; Fairlie DP; Goodnow CC; McCluskey J; Rossjohn J; Uldrich AP; Pellicci DG; Godfrey DI, 2015, 'Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers', Journal of Experimental Medicine, 212, pp. 1095 - 1108, http://dx.doi.org/10.1084/jem.20142110

Sapkota S; Brien JAE; Greenfield JR; Aslani P; Brien J-A; Milliken S; Goodnow C, 2015, 'A systematic review of interventions addressing adherence to anti-diabetic medications in patients with type 2 diabetes - Components of interventions', Plos One, 10, pp. e0128581, http://dx.doi.org/10.1371/journal.pone.0128581

Sapkota S; Brien J-AE; Greenfield JR; Aslani P, 2015, 'A Systematic Review of Interventions Addressing Adherence to Anti-Diabetic Medications in Patients with Type 2 Diabetes—Components of Interventions', PLOS ONE, 10, pp. e0128581 - e0128581, http://dx.doi.org/10.1371/journal.pone.0128581

Johar AS; Mastronardi C; Rojas-Villarraga A; Patel HR; Chuah A; Peng K; Higgins A; Milburn P; Palmer S; Silva-Lara MF; Velez JI; Andrews D; Field M; Huttley G; Goodnow C; Anaya JM; Arcos-Burgos M, 2015, 'Novel and rare functional genomic variants in multiple autoimmune syndrome and Sjögren's syndrome', Journal of Translational Medicine, 13, http://dx.doi.org/10.1186/s12967-015-0525-x

Lee P; Swarbrick MM; Greenfield JR, 2015, 'The sum of all browning in FGF21 therapeutics', Cell Metabolism, 21, pp. 795 - 796, http://dx.doi.org/10.1016/j.cmet.2015.05.018

Samocha-Bonet D; Chisholm DJ; Holst JJ; Greenfield JR; Milliken S; Goodnow C, 2015, 'L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like peptide-1 in type 2 diabetes patients', Nutrients, 7, pp. 2101 - 2108, http://dx.doi.org/10.3390/nu7042101

Liu Y; DeBoer K; de Kretser DM; O’Donnell L; O’Connor AE; Merriner DJ; Okuda H; Whittle B; Jans DA; Efthymiadis A; McLachlan RI; Ormandy CJ; Goodnow CC; Jamsai D; O’Bryan MK, 2015, 'LRGUK-1 Is Required for Basal Body and Manchette Function during Spermatogenesis and Male Fertility', Plos Genetics, 11, http://dx.doi.org/10.1371/journal.pgen.1005090

Siggs OM; Miosge LA; Daley SR; Asquith K; Foster PS; Liston A; Goodnow CC, 2015, 'Quantitative reduction of the TCR adapter protein SLP-76 unbalances immunity and immune regulation', Journal of Immunology, 194, pp. 2587 - 2595, http://dx.doi.org/10.4049/jimmunol.1400326

Hillen KM; Gather R; Enders A; Pircher H; Aichele P; Fisch P; Blumenthal B; Schamel WW; Straub T; Goodnow CC; Ehl S, 2015, 'T cell expansion is the limiting factor of virus control in mice with attenuated TCR signaling: Implications for human immunodeficiency', Journal of Immunology, 194, pp. 2725 - 2734, http://dx.doi.org/10.4049/jimmunol.1400328

Johar AS; Anaya JM; Andrews D; Patel HR; Field M; Goodnow C; Arcos-Burgos M, 2015, 'Candidate gene discovery in autoimmunity by using extreme phenotypes, next generation sequencing and whole exome capture', Autoimmunity Reviews, 14, pp. 204 - 209, http://dx.doi.org/10.1016/j.autrev.2014.10.021

Taupin D; Lam W; Rangiah D; McCallum L; Whittle B; Zhang Y; Andrews D; Field M; Goodnow CC; Cook MC, 2015, 'A deleterious RNF43 germline mutation in a severely affected serrated polyposis kindred', Human Genome Variation, 2, http://dx.doi.org/10.1038/hgv.2015.13

Lim SL; Qu ZP; Kortschak RD; Lawrence DM; Geoghegan J; Hempfling AL; Bergmann M; Goodnow CC; Ormandy CJ; Wong L; Mann J; Scott HS; Jamsai D; Adelson DL; O’Bryan MK, 2015, 'HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse', Plos Genetics, 11, http://dx.doi.org/10.1371/journal.pgen.1005620

Duong JK; Kumar SS; Furlong TJ; Kirkpatrick CM; Graham GG; Greenfield JR; Williams KM; Day RO, 2015, 'The pharmacokinetics of metformin and concentrations of haemoglobin A1C and lactate in Indigenous and non-Indigenous Australians with type 2 diabetes mellitus', British Journal of Clinical Pharmacology, 79, pp. 617 - 623, http://dx.doi.org/10.1111/bcp.12525

Lim SL; Qu ZP; Kortschak RD; Lawrence DM; Geoghegan J; Hempfling A-L; Bergmann M; Goodnow CC; Ormandy CJ; Wong L; Mann J; Scott HS; Jamsai D; Adelson DL; O'Bryan MK, 2015, 'Correction: HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.', PLoS Genet, 11, pp. e1005782, http://dx.doi.org/10.1371/journal.pgen.1005782

Ellyard JI; Jerjen R; Martin JL; Lee AYS; Field MA; Jiang SH; Cappello J; Naumann SK; Andrews TD; Scott HS; Casarotto MG; Goodnow CC; Chaitow J; Pascual V; Hertzog P; Alexander SI; Cook MC; Vinuesa CG, 2014, 'Brief report: Identification of a pathogenic variant in trex1 in early-onset cerebral systemic lupus erythematosus by whole-exome sequencing', Arthritis and Rheumatology, 66, pp. 3382 - 3386, http://dx.doi.org/10.1002/art.38824

Lee CE; Fulcher DA; Whittle B; Chand R; Fewings N; Field M; Andrews D; Goodnow CC; Cook MC, 2014, 'Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100', Blood, 124, pp. 2964 - 2972, http://dx.doi.org/10.1182/blood-2014-06-578542

Han BY; Wu S; Foo CS; Horton RM; Jenne CN; Watson SR; Whittle B; Goodnow CC; Cyster JG, 2014, 'Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment', Elife, 3, pp. 1 - 28, http://dx.doi.org/10.7554/eLife.03549

Zammit NW; Malle EK; Walters SN; Goodnow CC; Grey ST, 2014, 'Functional genomics identifies tnfaip3/A20 as a diabetes protective gene', DIABETOLOGIA, 57, pp. S103 - S103, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344386100229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sabouri Z; Schofield P; Horikawa K; Spierings E; Kipling D; Randall KL; Langley D; Roome B; Vazquez-Lombardi R; Rouet R; Hermes J; Chan TD; Brink R; Dunn-Walters DK; Christ D; Goodnow CC, 2014, 'Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity', Proceedings of the National Academy of Sciences of the United States of America, 111, pp. E2567 - E2575, http://dx.doi.org/10.1073/pnas.1406974111

Enders A; Short A; Miosge LA; Bergmann H; Sontani Y; Bertram EM; Whittle B; Balakishnan B; Yoshida K; Sjollema G; Field MA; Andrews TD; Hagiwara H; Goodnow CC, 2014, 'Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes', Proceedings of the National Academy of Sciences of the United States of America, 111, pp. 4513 - 4518, http://dx.doi.org/10.1073/pnas.1402739111

Wang JQ; Jeelall YS; Beutler B; Horikawa K; Goodnow CC, 2014, 'Consequences of the recurrent MYD88L265P somatic mutation for B cell tolerance', Journal of Experimental Medicine, 211, pp. 413 - 426, http://dx.doi.org/10.1084/jem.20131424

Altin JA; Daley SR; Howitt J; Rickards HJ; Batkin AK; Horikawa K; Prasad SJ; Nelms KA; Kumar S; Wu LC; Tan SS; Cook MC; Goodnow CC, 2014, 'Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells', Proceedings of the National Academy of Sciences of the United States of America, 111, pp. 2067 - 2074, http://dx.doi.org/10.1073/pnas.1322739111

Siggs OM; Yates AL; Schlenner S; Liston A; Lesage S; Goodnow CC, 2014, 'A ZAP-70 kinase domain variant prevents thymocyte-positive selection despite signalling CD69 induction', Immunology, 141, pp. 587 - 595, http://dx.doi.org/10.1111/imm.12220

Bull KR; Mason T; Rimmer AJ; Crockford TL; Silver KL; Bouriez-Jones T; Hough TA; Chaudhry S; Roberts ISD; Goodnow CC; Cornall RJ, 2014, 'Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome', Journal of Pathology, 233, pp. 18 - 26, http://dx.doi.org/10.1002/path.4308

Cho V; Mei Y; Sanny A; Chan S; Enders A; Bertram EM; Tan A; Goodnow CC; Daniel Andrews T, 2014, 'The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA', Genome Biology, 15, http://dx.doi.org/10.1186/gb-2014-15-1-r26

Daley SR; Coakley KM; Hu DY; Randall KL; Jenne CN; Limnander A; Myers DR; Polakos NK; Enders A; Roots C; Balakishnan B; Miosge LA; Sjollema G; Bertram EM; Field MA; Shao Y; Daniel Andrews T; Whittle B; Whitney Barnes S; Walker JR; Cyster JG; Goodnow CC; Roose JP, 2013, 'Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies', Elife, 2013, http://dx.doi.org/10.7554/eLife.01020

Jamsai D; Clark BJ; Smith SJ; Whittle B; Goodnow CC; Ormandy CJ; O'Bryan MK, 2013, 'A Missense Mutation in the Transcription Factor ETV5 Leads to Sterility, Increased Embryonic and Perinatal Death, Postnatal Growth Restriction, Renal Asymmetry and Polydactyly in the Mouse', Plos One, 8, http://dx.doi.org/10.1371/journal.pone.0077311

O'Bryan MK; Clark BJ; McLaughlin EA; D'Sylva RJ; O'Donnell L; Wilce JA; Sutherland J; O'Connor AE; Whittle B; Goodnow CC; Ormandy CJ; Jamsai D, 2013, 'RBM5 Is a Male Germ Cell Splicing Factor and Is Required for Spermatid Differentiation and Male Fertility', Plos Genetics, 9, pp. e1003628, http://dx.doi.org/10.1371/journal.pgen.1003628

Teh CE; Horikawa K; Arnold CN; Beutler B; Kucharska EM; Vinuesa CG; Bertram EM; Goodnow CC; Enders A, 2013, 'Heterozygous mis-sense mutations in Prkcb as a critical determinant of anti-polysaccharide antibody formation', Genes and Immunity, 14, pp. 223 - 233, http://dx.doi.org/10.1038/gene.2013.11

Pratama A; Ramiscal RR; Silva DG; Das SK; Athanasopoulos V; Fitch J; Botelho NK; Chang PP; Hu X; Hogan JJ; Maña P; Bernal D; Korner H; Yu D; Goodnow CC; Cook MC; Vinuesa CG, 2013, 'Roquin-2 shares functions with its paralog roquin-1 in the repression of mrnas controlling t follicular helper cells and systemic inflammation', Immunity, 38, pp. 669 - 680, http://dx.doi.org/10.1016/j.immuni.2013.01.011

Andrews TD; Sjollema G; Goodnow CC, 2013, 'Understanding the immunological impact of the human mutation explosion', Trends in Immunology, 34, pp. 99 - 106, http://dx.doi.org/10.1016/j.it.2012.12.001

Daley SR; Hu DY; Goodnow CC, 2013, 'Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB', Journal of Experimental Medicine, 210, pp. 269 - 285, http://dx.doi.org/10.1084/jem.20121458

Bergmann H; Yabas M; Short A; Miosge L; Barthel N; Teh CE; Roots CM; Bull KR; Jeelall Y; Horikawa K; Whittle B; Balakishnan B; Sjollema G; Bertram EM; Mackay F; Rimmer AJ; Cornall RJ; Field MA; Andrews TD; Goodnow CC; Enders A, 2013, 'B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPl2A', Journal of Experimental Medicine, 210, pp. 31 - 40, http://dx.doi.org/10.1084/jem.20121076

Crawford G; Enders A; Gileadi U; Stankovic S; Zhang Q; Lambe T; Crockford TL; Lockstone HE; Freeman A; Arkwright PD; Smart JM; Ma CS; Tangye SG; Goodnow CC; Cerundolo V; Godfrey DI; Su HC; Randall KL; Cornall RJ, 2013, 'DOCK8 is critical for the survival and function of NKT cells', Blood, 122, pp. 2052 - 2061, http://dx.doi.org/10.1182/blood-2013-02-482331

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