By Associate Professor Mandy Ballinger

Journal articles

Mahendran K; Ballinger M; Kirk J; Thomas D; Tattersall M, 2012, 'Pathogenic germline TP53 mutations in adult sarcoma patients; implications for treatment and screening – description of an upcoming project', Hereditary cancer in clinical practice, 10, pp. A61 - A61, http://dx.doi.org/10.1186/1897-4287-10-s2-a61

Burch ML; Ballinger ML; Yang SNY; Getachew R; Itman C; Loveland K; Osman N; Little PJ, 2010, 'Thrombin stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by protease-activated receptor-1 transactivation of the transforming growth factor βtype I receptor', Journal of Biological Chemistry, 285, pp. 26798 - 26805, http://dx.doi.org/10.1074/jbc.M109.092767

Ballinger ML; Osman N; Hashimura K; Haan JBD; Jandeleit-Dahm K; Allen T; Tannock LR; Rutledge JC; Little PJ, 2010, 'Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo', Journal of Cellular and Molecular Medicine, 14, pp. 1408 - 1418, http://dx.doi.org/10.1111/j.1582-4934.2009.00902.x

Burch ML; Yang SNY; Ballinger ML; Getachew R; Osman N; Little PJ, 2010, 'TGF-β stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2', Cellular and Molecular Life Sciences, 67, pp. 2077 - 2090, http://dx.doi.org/10.1007/s00018-010-0315-9

Cardoso LEM; Little PJ; Ballinger ML; Chan CK; Braun KR; Potter-Perigo S; Bornfeldt KE; Kinsella MG; Wight TN, 2010, 'Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways', Journal of Biological Chemistry, 285, pp. 6987 - 6995, http://dx.doi.org/10.1074/jbc.M109.088674

Getachew R; Ballinger ML; Burch ML; Little PJ; Osman N, 2010, 'Characterisation of Ki11502 as a potent inhibitor of PDGF β receptor-mediated proteoglycan synthesis in vascular smooth muscle cells', European Journal of Pharmacology, 626, pp. 186 - 192, http://dx.doi.org/10.1016/j.ejphar.2009.09.066

Getachew R; Ballinger M; Burch M; Reid J; Khachigian LM, 2010, 'PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminologycan elongationon biglycan and increases binding to LDL.', Endocrinology, 151, pp. 4356 - 4367

Ballinger ML; Ivey ME; Osman N; Thomas WG; Little PJ, 2009, 'Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL', Atherosclerosis, 205, pp. 451 - 457, http://dx.doi.org/10.1016/j.atherosclerosis.2009.01.024

Yang SNY; Burch ML; Getachew R; Ballinger ML; Osman N; Little PJ, 2009, 'Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation', Archives of Physiology and Biochemistry, 115, pp. 147 - 154, http://dx.doi.org/10.1080/13813450903110754

Osman N; Ballinger ML; Dadlani HM; Getachew R; Burch ML; Little PJ, 2008, 'p38 MAP kinase mediated proteoglycan synthesis as a target for the prevention of atherosclerosis', Cardiovascular and Hematological Disorders Drug Targets, 8, pp. 287 - 292, http://dx.doi.org/10.2174/187152908786786205

Ballinger ML; Osman N; Wilks AF; Su S; Burns CJ; Bu X; Little PJ, 2008, 'Pyrido-pyrimidine derivative CYC10424 inhibits glycosaminoglycan changes on vascular smooth muscle-derived proteoglycans and reduces lipoprotein binding', Journal of Cardiovascular Pharmacology, 52, pp. 403 - 412, http://dx.doi.org/10.1097/FJC.0b013e31818a8907

Dadlani H; Osman N; Ballinger ML; Marasco S; Little PJ, 2008, 'Calcific aortic valve disease and hypertension', Current Hypertension Reviews, 4, pp. 107 - 113, http://dx.doi.org/10.2174/157340208784245884

Dadlani H; Ballinger ML; Osman N; Getachew R; Little PJ, 2008, 'Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle', Journal of Biological Chemistry, 283, pp. 7844 - 7852, http://dx.doi.org/10.1074/jbc.M703125200

Little PJ; Ballinger ML; Survase S; Osman N; Ogru E; Geytenbeek S; Bruemmer D; Nigro J, 2008, 'Phosphorylated troglitazone activates PPARγ and inhibits vascular smooth muscle cell proliferation and proteoglycan synthesis', Journal of Cardiovascular Pharmacology, 51, pp. 274 - 279, http://dx.doi.org/10.1097/FJC.0b013e3181626ce7

Little PJ; Ballinger ML; Burch ML; Osman N, 2008, 'Biosynthesis of natural and hyperelongated chondroitin sulfate glycosaminoglycans: new insights into an elusive process.', Open Biochem J, 2, pp. 135 - 142, http://dx.doi.org/10.2174/1874091X00802010135

Little PJ; Osman N; de Dios ST; Cemerlang N; Ballinger M; Nigro J, 2007, 'Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: Thiazolidinediones (glitazones) have enhanced activity under high glucose conditions', Cardiovascular Diabetology, 6, http://dx.doi.org/10.1186/1475-2840-6-33

Grande-Allen KJ; Osman N; Ballinger ML; Dadlani H; Marasco S; Little PJ, 2007, 'Glycosaminoglycan synthesis and structure as targets for the prevention of calcific aortic valve disease', Cardiovascular Research, 76, pp. 19 - 28, http://dx.doi.org/10.1016/j.cardiores.2007.05.014

Little PJ; Ballinger ML; Osman N, 2007, 'Vascular wall proteoglycan synthesis and structure as a target for the prevention of atherosclerosis', Vascular Health and Risk Management, 3, pp. 117 - 124

de Dios ST; Frontanilla KV; Nigro J; Ballinger ML; Ivey ME; Cawson EA; Little PJ, 2007, 'Regulation of the atherogenic properties of vascular smooth muscle proteoglycans by oral anti-hyperglycemic agents', Journal of Diabetes and Its Complications, 21, pp. 108 - 117, http://dx.doi.org/10.1016/j.jdiacomp.2006.03.003

Nigro J; Ballinger M; Osman N; Dart A; Little P, 2005, 'Anti-Atherogenic Role of Peroxisome Proliferator-Activated Receptor Ligands', Current Cardiology Reviews, 1, pp. 89 - 102, http://dx.doi.org/10.2174/1573403054021654

Ballinger ML; Thomas MC; Nigro J; Ivey ME; Dilley RJ; Little PJ, 2005, 'Glycated and carboxy-methylated proteins do not directly activate human vascular smooth muscle cells', Kidney International, 68, pp. 2756 - 2765, http://dx.doi.org/10.1111/j.1523-1755.2005.00746.x

Nigro J; Ballinger ML; Survase S; Osman N; Little PJ, 2005, 'New approaches to regulating the chondroitin/dermatan sulfate glycosaminoglycan component of the vascular extracellular matrix.', Thescientificworldjournal, 5, pp. 515 - 520, http://dx.doi.org/10.1100/tsw.2005.69

Nigro J; Ballinger ML; Dilley RJ; Jennings GLR; Wight TN; Little PJ, 2004, 'Fenofibrate modifies human vascular smooth muscle proteoglycans and reduces lipoprotein binding', Diabetologia, 47, pp. 2105 - 2113, http://dx.doi.org/10.1007/s00125-004-1588-z

Ballinger ML; Nigro J; Frontanilla KV; Dart AM; Little PJ, 2004, 'Regulation of glycosaminoglycan structure and atherogenesis', Cellular and Molecular Life Sciences, 61, pp. 1296 - 1306, http://dx.doi.org/10.1007/s00018-004-3389-4

Back to profile page